Publications:

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Recent Advances in Covalent Drug Discovery.

Pharmaceuticals (Basel, Switzerland)

Schaefer, Daniel D; Cheng, Xinlai X

Publication Date: 2023-04-28

Variant appearance in text: KRAS: Q99L

PubMed Link: 37242447

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• Main text
• pharmaceuticals-16-00663.pdf

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Direct GDP-KRASG12C inhibitors and mechanisms of resistance: the tip of the iceberg.

Therapeutic Advances In Medical Oncology

Rosen, Joshua C JC; Sacher, Adrian A; Tsao, Ming-Sound MS

Publication Date: 2023

Variant appearance in text: KRAS: Q99L

PubMed Link: 36950276

Variant Present in the following documents:

• Main text
• 10.1177_17588359231160141.pdf

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Targeted therapies for KRAS-mutant non-small cell lung cancer: from preclinical studies to clinical development-a narrative review.

Translational Lung Cancer Research

Santarpia, Mariacarmela M; Ciappina, Giuliana G; Spagnolo, Calogera Claudia CC; Squeri, Andrea A; Passalacqua, Maria Ilenia MI; Aguilar, Andrés A; Gonzalez-Cao, Maria M; Giovannetti, Elisa E; Silvestris, Nicola N; Rosell, Rafael R

Publication Date: 2023-02-28

Variant appearance in text: KRAS: Q99L

PubMed Link: 36895930

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• Main text
• tlcr-12-02-346.pdf

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KRAS Mutations in Solid Tumors: Characteristics, Current Therapeutic Strategy, and Potential Treatment Exploration.

Journal Of Clinical Medicine

Yang, Yunkai Y; Zhang, Huan H; Huang, Shanshan S; Chu, Qian Q

Publication Date: 2023-01-16

Variant appearance in text: KRAS: Q99L

PubMed Link: 36675641

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• Main text
• jcm-12-00709.pdf

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Targeting KRAS G12C mutations in colorectal cancer.

Gastroenterology Report

Zhao, Ming-He MH; Wu, Ai-Wen AW

Publication Date: 2023

Variant appearance in text: KRAS: Q99L

PubMed Link: 36632627

Variant Present in the following documents:

• Main text
• goac083.pdf

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Identification of Small GTPases That Phosphorylate IRF3 through TBK1 Activation Using an Active Mutant Library Screen.

Biomolecules & Therapeutics

Yu, Jae-Hyun JH; Moon, Eun-Yi EY; Kim, Jiyoon J; Koo, Ja Hyun JH

Publication Date: 2023-01-01

Variant appearance in text: KRAS: Q99L

PubMed Link: 36579460

Variant Present in the following documents:

• bt-31-1-48.pdf

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KRAS in NSCLC: State of the Art and Future Perspectives.

Cancers

Cascetta, Priscilla P; Marinello, Arianna A; Lazzari, Chiara C; Gregorc, Vanesa V; Planchard, David D; Bianco, Roberto R; Normanno, Nicola N; Morabito, Alessandro A

Publication Date: 2022-11-04

Variant appearance in text: KRAS: Q99L

PubMed Link: 36358848

Variant Present in the following documents:

• Main text
• cancers-14-05430.pdf

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Molecular Biology and Therapeutic Perspectives for K-Ras Mutant Non-Small Cell Lung Cancers.

Cancers

Cekani, Elona E; Epistolio, Samantha S; Dazio, Giulia G; Cefalì, Marco M; Wannesson, Luciano L; Frattini, Milo M; Froesch, Patrizia P

Publication Date: 2022-08-24

Variant appearance in text: KRAS: Q99L

PubMed Link: 36077640

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• Main text
• cancers-14-04103.pdf

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The current state of the art and future trends in RAS-targeted cancer therapies.

Nature Reviews. Clinical Oncology

Punekar, Salman R SR; Velcheti, Vamsidhar V; Neel, Benjamin G BG; Wong, Kwok-Kin KK

Publication Date: 2022-10

Variant appearance in text: KRAS: Q99L

PubMed Link: 36028717

Variant Present in the following documents:

• Main text
• 41571_2022_Article_671.pdf

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Conquering oncogenic KRAS and its bypass mechanisms.

Theranostics

Hou, Pingping P; Wang, Y Alan YA

Publication Date: 2022

Variant appearance in text: KRAS: Q99L

PubMed Link: 35966590

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• Main text
• thnov12p5691.pdf

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Targeting KRAS G12C-Mutated Advanced Colorectal Cancer: Research and Clinical Developments.

Oncotargets And Therapy

Ji, Jingran J; Wang, Chongkai C; Fakih, Marwan M

Publication Date: 2022

Variant appearance in text: KRAS: Q99L

PubMed Link: 35837349

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• Main text
• ott-15-747.pdf

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Targeting KRAS Mutant in Non-Small Cell Lung Cancer: Novel Insights Into Therapeutic Strategies.

Frontiers In Oncology

Désage, Anne-Laure AL; Léonce, Camille C; Swalduz, Aurélie A; Ortiz-Cuaran, Sandra S

Publication Date: 2022

Variant appearance in text: KRAS: Q99L

PubMed Link: 35251972

Variant Present in the following documents:

• Main text
• fonc-12-796832.pdf

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Targeting KRAS in Non-Small Cell Lung Cancer.

Frontiers In Oncology

Corral de la Fuente, Elena E; Olmedo Garcia, Maria Eugenia ME; Gomez Rueda, Ana A; Lage, Yolanda Y; Garrido, Pilar P

Publication Date: 2021

Variant appearance in text: KRAS: Q99L

PubMed Link: 35083149

Variant Present in the following documents:

• Main text
• fonc-11-792635.pdf

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A Breakthrough Brought about by Targeting KRASG12C: Nonconformity Is Punished.

Cancers

Ning, Wenjuan W; Yang, Zhang Z; Kocher, Gregor J GJ; Dorn, Patrick P; Peng, Ren-Wang RW

Publication Date: 2022-01-13

Variant appearance in text: KRAS: Q99L

PubMed Link: 35053550

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• Main text

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A Breakthrough Brought about by Targeting KRASG12C: Nonconformity Is Punished.

Cancers

Ning, Wenjuan W; Yang, Zhang Z; Kocher, Gregor J GJ; Dorn, Patrick P; Peng, Ren-Wang RW

Publication Date: 2022-01-13

Variant appearance in text: KRAS: Q99L

PubMed Link: 35053550

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• Main text

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Resistance to KRASG12C Inhibitors in Non-Small Cell Lung Cancer.

Frontiers In Oncology

Blaquier, Juan Bautista JB; Cardona, Andrés Felipe AF; Recondo, Gonzalo G

Publication Date: 2021

Variant appearance in text: KRAS: Q99L

PubMed Link: 35004309

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• Main text

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KRAS mutation: from undruggable to druggable in cancer.

Signal Transduction And Targeted Therapy

Huang, Lamei L; Guo, Zhixing Z; Wang, Fang F; Fu, Liwu L

Publication Date: 2021-11-15

Variant appearance in text: KRAS: Q99L

PubMed Link: 34776511

Variant Present in the following documents:

• Main text
• 41392_2021_Article_780.pdf

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KRAS G12C Mutations in NSCLC: From Target to Resistance.

Cancers

Addeo, Alfredo A; Banna, Giuseppe Luigi GL; Friedlaender, Alex A

Publication Date: 2021-05-21

Variant appearance in text: KRAS: Q99L

PubMed Link: 34064232

Variant Present in the following documents:

• Main text
• cancers-13-02541.pdf

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Therapeutic effects of the novel Leucyl-tRNA synthetase inhibitor BC-LI-0186 in non-small cell lung cancer.

Therapeutic Advances In Medical Oncology

Kim, Eun Young EY; Lee, Jin Gu JG; Lee, Jung Mo JM; Kim, Arum A; Yoo, Hee Chan HC; Kim, Kibum K; Lee, Minji M; Lee, Chulho C; Han, Gyoonhee G; Han, Jung Min JM; Chang, Yoon Soo YS

Publication Date: 2019

Variant appearance in text: KRAS: Q99L

PubMed Link: 31205503

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• Main text

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