Structural bioinformatics enhances mechanistic interpretation of genomic variation, demonstrated through the analyses of 935 distinct RAS family mutations.
Bioinformatics (Oxford, England)
Tripathi, Swarnendu S; Dsouza, Nikita R NR; Urrutia, Raul R; Zimmermann, Michael T MT
Sharma, Yogita Y; Miladi, Milad M; Dukare, Sandeep S; Boulay, Karine K; Caudron-Herger, Maiwen M; Groß, Matthias M; Backofen, Rolf R; Diederichs, Sven S
Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.
Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Detection of somatic mutations by high-resolution DNA melting (HRM) analysis in multiple cancers.
Plos One
Gonzalez-Bosquet, Jesus J; Calcei, Jacob J; Wei, Jun S JS; Garcia-Closas, Montserrat M; Sherman, Mark E ME; Hewitt, Stephen S; Vockley, Joseph J; Lissowska, Jolanta J; Yang, Hannah P HP; Khan, Javed J; Chanock, Stephen S