Publications:

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Analysis of RAS and drug induced homo- and heterodimerization of RAF and KSR1 proteins in living cells using split Nanoluc luciferase.

Cell Communication And Signaling : Ccs

Rohrer, Lino L; Spohr, Corinna C; Beha, Carina C; Griffin, Ricarda R; Braun, Sandra S; Halbach, Sebastian S; Brummer, Tilman T

Publication Date: 2023-06-14

Variant appearance in text: KRAS: Q61R

PubMed Link: 37316874

Variant Present in the following documents:

• Main text

View BVdb publication page

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RAS-targeted cancer therapy: Advances in drugging specific mutations.

Medcomm

Liu, Cen C; Ye, Danyang D; Yang, Hongliu H; Chen, Xu X; Su, Zhijun Z; Li, Xia X; Ding, Mei M; Liu, Yonggang Y

Publication Date: 2023-06

Variant appearance in text: KRAS: Q61R

PubMed Link: 37250144

Variant Present in the following documents:

• Main text
• MCO2-4-e285.pdf

View BVdb publication page

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Targeting small GTPases: emerging grasps on previously untamable targets, pioneered by KRAS.

Signal Transduction And Targeted Therapy

Yin, Guowei G; Huang, Jing J; Petela, Johnny J; Jiang, Hongmei H; Zhang, Yuetong Y; Gong, Siqi S; Wu, Jiaxin J; Liu, Bei B; Shi, Jianyou J; Gao, Yijun Y

Publication Date: 2023-05-23

Variant appearance in text: KRAS: Q61R

PubMed Link: 37221195

Variant Present in the following documents:

• Main text

View BVdb publication page

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Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.

Biorxiv : The Preprint Server For Biology

Ratnasinghe, Brian D BD; Haque, Neshatul N; Wagenknecht, Jessica B JB; Jensen, Davin R DR; Esparza, Guadalupe V GV; Leverence, Elise N EN; De Assuncao, Thiago Milech TM; Mathison, Angela J AJ; Lomberk, Gwen G; Smith, Brian C BC; Volkman, Brian F BF; Urrutia, Raul R; Zimmermann, Michael T MT

Publication Date: 2023-04-28

Variant appearance in text: KRAS: Q61R

PubMed Link: 37207265

Variant Present in the following documents:

• Main text
• nihpp-2023.04.28.536249v1.pdf
• media-1.pdf

View BVdb publication page

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ErbB signalling is a potential therapeutic target for vascular lesions with fibrous component.

Elife

Jauhiainen, Suvi S; Ilmonen, Henna H; Vuola, Pia P; Rasinkangas, Heta H; Pulkkinen, Heidi H HH; Keränen, Sara S; Kiema, Miika M; Liikkanen, Jade J JJ; Laham Karam, Nihay N; Laidinen, Svetlana S; Beter, Mustafa M; Aavik, Einari E; Lappalainen, Kimmo K; Lohi, Jouko J; Aronniemi, Johanna J; Örd, Tiit T; Kaikkonen, Minna U MU; Salminen, Päivi P; Tukiainen, Erkki E; Ylä-Herttuala, Seppo S; Laakkonen, Johanna P JP

Publication Date: 2023-05-18

Variant appearance in text: KRAS: Q61R

PubMed Link: 37199488

Variant Present in the following documents:

• elife-82543.pdf

View BVdb publication page

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Correlation of gene expression profiles to identify pancreatic cancer cell lines that best model primary human tumors.

Translational Cancer Research

Hu, Yan Y; Gao, Peng P; Xu, Gaoqi G; Sun, Jiao J; Xin, Wenxiu W; Kong, Sisi S; Ding, Haiying H; Zhu, Junfeng J; Fang, Luo L

Publication Date: 2023-04-28

Variant appearance in text: KRAS: Q61R

PubMed Link: 37180676

Variant Present in the following documents:

• tcr-12-04-980-prf.pdf

View BVdb publication page

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The efficacy of immune checkpoint inhibitors in biliary tract cancer with KRAS mutation.

Therapeutic Advances In Gastroenterology

Jeong, Sun Young SY; Hong, Jung Yong JY; Park, Joon Oh JO; Park, Young Suk YS; Lim, Ho Yeong HY; Jang, Jae Yeon JY; Jeon, Youngkyung Y; Kim, Seung Tae ST

Publication Date: 2023

Variant appearance in text: KRAS: Q61R

PubMed Link: 37163165

Variant Present in the following documents:

• Main text
• 10.1177_17562848231170484.pdf

View BVdb publication page

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KRAS mutation: The booster of pancreatic ductal adenocarcinoma transformation and progression.

Frontiers In Cell And Developmental Biology

Zhang, Zining Z; Zhang, Heng H; Liao, Xiang X; Tsai, Hsiang-I HI

Publication Date: 2023

Variant appearance in text: KRAS: Q61R

PubMed Link: 37152291

Variant Present in the following documents:

• Main text
• fcell-11-1147676.pdf

View BVdb publication page

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Somatic and germline aberrations in homologous recombination repair genes in Chinese prostate cancer patients.

Frontiers In Oncology

Liu, Yixiao Y; Jin, Bo B; Shen, Cheng C; Gao, Xianshu X; Qi, Xin X; Ma, Mingwei M; Li, Hongzhen H; Hao, Han H; Tang, Qi Q; Yang, Kaiwei K; Mi, Yue Y; Guan, Jie J; Feng, Xuero X; He, Zhisong Z; Li, Haixia H; Yu, Wei W

Publication Date: 2023

Variant appearance in text: KRAS: 182A>G; Q61R

PubMed Link: 37064136

Variant Present in the following documents:

• Table_1.xlsx, sheet 1

View BVdb publication page

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Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.

Nature

Abbosh, Christopher C; Frankell, Alexander M AM; Harrison, Thomas T; Kisistok, Judit J; Garnett, Aaron A; Johnson, Laura L; Veeriah, Selvaraju S; Moreau, Mike M; Chesh, Adrian A; Chaunzwa, Tafadzwa L TL; Weiss, Jakob J; Schroeder, Morgan R MR; Ward, Sophia S; Grigoriadis, Kristiana K; Shahpurwalla, Aamir A; Litchfield, Kevin K; Puttick, Clare C; Biswas, Dhruva D; Karasaki, Takahiro T; Black, James R M JRM; Martínez-Ruiz, Carlos C; Bakir, Maise Al MA; Pich, Oriol O; Watkins, Thomas B K TBK; Lim, Emilia L EL; Huebner, Ariana A; Moore, David A DA; Godin-Heymann, Nadia N; L'Hernault, Anne A; Bye, Hannah H; Odell, Aaron A; Roberts, Paula P; Gomes, Fabio F; Patel, Akshay J AJ; Manzano, Elizabeth E; Hiley, Crispin T CT; Carey, Nicolas N; Riley, Joan J; Cook, Daniel E DE; Hodgson, Darren D; Stetson, Daniel D; Barrett, J Carl JC; Kortlever, Roderik M RM; Evan, Gerard I GI; Hackshaw, Allan A; Daber, Robert D RD; Shaw, Jacqui A JA; Aerts, Hugo J W L HJWL; Licon, Abel A; Stahl, Josh J; Jamal-Hanjani, Mariam M; , ; Birkbak, Nicolai J NJ; McGranahan, Nicholas N; Swanton, Charles C

Publication Date: 2023-04-13

Variant appearance in text: KRAS: Q61R

PubMed Link: 37055640

Variant Present in the following documents:

• EMS176197-supplement-Supplementary_Table_1.xlsx, sheet 18

View BVdb publication page

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Pretreatment Plasma Circulating Tumor DNA RAS/BRAF Mutational Status in Refractory Metastatic Colorectal Cancer Patients Who Are Candidates for Anti-EGFR Rechallenge Therapy: A Pooled Analysis of the CAVE and VELO Clinical Trials.

Cancers

Ciardiello, Davide D; Napolitano, Stefania S; Famiglietti, Vincenzo V; Esposito, Lucia L; De Falco, Vincenzo V; Di Liello, Alessandra A; Avallone, Antonio A; Maiello, Evaristo E; Pietrantonio, Filippo F; Cremolini, Chiara C; Zampino, Maria Giulia MG; Fazio, Nicola N; Troiani, Teresa T; Martinelli, Erika E; Ciardiello, Fortunato F; Martini, Giulia G

Publication Date: 2023-04-01

Variant appearance in text: KRAS: Q61R

PubMed Link: 37046778

Variant Present in the following documents:

• cancers-15-02117.pdf

View BVdb publication page

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: KRAS: Q61R

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 2
• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3
• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2

View BVdb publication page

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Pathogenic genomic alterations in Chinese pancreatic cancer patients and their therapeutical implications.

Cancer Medicine

Zhao, Zhiming Z; Li, Xiaomo X; Wang, Fei F; Xu, Yong Y; Liu, Si S; Han, Quanli Q; Yang, Zhiying Z; Huang, Weiwei W; Yin, Zhuzeng Z; Liu, Qu Q; Tan, Haidong H; Ma, Tonghui T; Si, Shuang S; Huang, Jia J; Yuan, Hongling H; Li, Wei W; Liu, Rong R

Publication Date: 2023-03-31

Variant appearance in text: KRAS: Q61R

PubMed Link: 36999792

Variant Present in the following documents:

• CAM4-12-11672.pdf

View BVdb publication page

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Non-Oncogene Addiction of KRAS-Mutant Cancers to IL-1β via Versican and Mononuclear IKKβ.

Cancers

Spella, Magda M; Ntaliarda, Giannoula G; Skiadas, Georgios G; Lamort, Anne-Sophie AS; Vreka, Malamati M; Marazioti, Antonia A; Lilis, Ioannis I; Bouloukou, Eleni E; Giotopoulou, Georgia A GA; Pepe, Mario A A MAA; Weiss, Stefanie A I SAI; Petrera, Agnese A; Hauck, Stefanie M SM; Koch, Ina I; Lindner, Michael M; Hatz, Rudolph A RA; Behr, Juergen J; Arendt, Kristina A M KAM; Giopanou, Ioanna I; Brunn, David D; Savai, Rajkumar R; Jenne, Dieter E DE; de Château, Maarten M; Yull, Fiona E FE; Blackwell, Timothy S TS; Stathopoulos, Georgios T GT

Publication Date: 2023-03-20

Variant appearance in text: KRAS: Q61R

PubMed Link: 36980752

Variant Present in the following documents:

• cancers-15-01866.pdf

View BVdb publication page

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RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer.

Nature

Jbara, Amina A; Lin, Kuan-Ting KT; Stossel, Chani C; Siegfried, Zahava Z; Shqerat, Haya H; Amar-Schwartz, Adi A; Elyada, Ela E; Mogilevsky, Maxim M; Raitses-Gurevich, Maria M; Johnson, Jared L JL; Yaron, Tomer M TM; Ovadia, Ofek O; Jang, Gun Ho GH; Danan-Gotthold, Miri M; Cantley, Lewis C LC; Levanon, Erez Y EY; Gallinger, Steven S; Krainer, Adrian R AR; Golan, Talia T; Karni, Rotem R

Publication Date: 2023-03-22

Variant appearance in text: KRAS: Q61R

PubMed Link: 36949200

Variant Present in the following documents:

• 41586_2023_5820_MOESM4_ESM.xlsx, sheet 3
• 41586_2023_5820_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Kras oncogene ablation prevents resistance in advanced lung adenocarcinoma.

The Journal Of Clinical Investigation

Salmón, Marina M; Álvarez-Díaz, Ruth R; Fustero-Torre, Coral C; Brehey, Oksana O; Lechuga, Carmen G CG; Sanclemente, Manuel M; Fernández-García, Fernando F; López-García, Alejandra A; Martín-Guijarro, María Carmen MC; Rodríguez-Perales, Sandra S; Bousquet-Mur, Emily E; Morales-Cacho, Lucía L; Mulero, Francisca F; Al-Shahrour, Fátima F; Martínez, Lola L; Domínguez, Orlando O; Caleiras, Eduardo E; Ortega, Sagrario S; Guerra, Carmen C; Musteanu, Monica M; Drosten, Matthias M; Barbacid, Mariano M

Publication Date: 2023-03-16

Variant appearance in text: KRAS: Q61R

PubMed Link: 36928090

Variant Present in the following documents:

• jci-133-164413.pdf

View BVdb publication page

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Recapitulating thyroid cancer histotypes through engineering embryonic stem cells.

Nature Communications

Veschi, Veronica V; Turdo, Alice A; Modica, Chiara C; Verona, Francesco F; Di Franco, Simone S; Gaggianesi, Miriam M; Tirrò, Elena E; Di Bella, Sebastiano S; Iacono, Melania Lo ML; Pantina, Vincenzo Davide VD; Porcelli, Gaetana G; Mangiapane, Laura Rosa LR; Bianca, Paola P; Rizzo, Aroldo A; Sciacca, Elisabetta E; Pillitteri, Irene I; Vella, Veronica V; Belfiore, Antonino A; Bongiorno, Maria Rita MR; Pistone, Giuseppe G; Memeo, Lorenzo L; Colarossi, Lorenzo L; Giuffrida, Dario D; Colarossi, Cristina C; Vigneri, Paolo P; Todaro, Matilde M; Stassi, Giorgio G

Publication Date: 2023-03-11

Variant appearance in text: KRAS: 182A>G; Q61R; rs121913240

PubMed Link: 36906579

Variant Present in the following documents:

• 41467_2023_36922_MOESM4_ESM.xls, sheet 2

View BVdb publication page

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Discovering Synergistic Compounds with BYL-719 in PI3K Overactivated Basal-like PDXs.

Cancers

Boyd, David C DC; Zboril, Emily K EK; Olex, Amy L AL; Leftwich, Tess J TJ; Hairr, Nicole S NS; Byers, Holly A HA; Valentine, Aaron D AD; Altman, Julia E JE; Alzubi, Mohammad A MA; Grible, Jacqueline M JM; Turner, Scott A SA; Ferreira-Gonzalez, Andrea A; Dozmorov, Mikhail G MG; Harrell, J Chuck JC

Publication Date: 2023-03-03

Variant appearance in text: KRAS: 182A>G

PubMed Link: 36900375

Variant Present in the following documents:

• cancers-15-01582.pdf

View BVdb publication page

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Characterization of clonal immunoglobulin heavy V-D-J gene rearrangements in Chinese patients with chronic lymphocytic leukemia: Clinical features and molecular profiles.

Frontiers In Oncology

Deng, Xinyue X; Zhang, Meilan M; Wang, Jiachen J; Zhou, Xiaoxi X; Xiao, Min M

Publication Date: 2023

Variant appearance in text: KRAS: Q61R

PubMed Link: 36874132

Variant Present in the following documents:

• Table_1.xlsx, sheet 1

View BVdb publication page

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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery

Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI

Publication Date: 2023-03-02

Variant appearance in text: KRAS: 182A>G; Gln61Arg; rs121913240

PubMed Link: 36862804

Variant Present in the following documents:

• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 10
• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 6

View BVdb publication page

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High-risk multiple myeloma predicted by circulating plasma cells and its genetic characteristics.

Frontiers In Oncology

Xia, Yuan Y; Shen, Na N; Zhang, Run R; Wu, Yujie Y; Shi, Qinglin Q; Li, Jianyong J; Chen, Lijuan L; Xu, Min M; Jin, Yuanyuan Y

Publication Date: 2023

Variant appearance in text: rs121913240

PubMed Link: 36845679

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: KRAS: 182A>G; Gln61Arg

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Pan-cancer clinical impact of latent drivers from double mutations.

Communications Biology

Yavuz, Bengi Ruken BR; Tsai, Chung-Jung CJ; Nussinov, Ruth R; Tuncbag, Nurcan N

Publication Date: 2023-02-20

Variant appearance in text: KRAS: Q61R

PubMed Link: 36808143

Variant Present in the following documents:

• 42003_2023_4519_MOESM3_ESM.xlsx, sheet 3

View BVdb publication page

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Significance of logistic regression scoring model based on natural killer cell-mediated cytotoxic pathway in the diagnosis of colon cancer.

Frontiers In Immunology

Ye, Zhen Z; Zhang, Huanhuan H; Liang, Jianwei J; Yi, Shuying S; Zhan, Xianquan X

Publication Date: 2023

Variant appearance in text: KRAS: Q61R; rs121913240

PubMed Link: 36742322

Variant Present in the following documents:

• Table_7.xlsx, sheet 1

View BVdb publication page

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Whole-cell energy modeling reveals quantitative changes of predicted energy flows in RAS mutant cancer cell lines.

Iscience

Sevrin, Thomas T; Strasser, Lisa L; Ternet, Camille C; Junk, Philipp P; Caffarini, Miriam M; Prins, Stella S; D'Arcy, Cian C; Catozzi, Simona S; Oliviero, Giorgio G; Wynne, Kieran K; Kiel, Christina C; Luthert, Philip J PJ

Publication Date: 2023-02-17

Variant appearance in text: KRAS: Q61R

PubMed Link: 36711246

Variant Present in the following documents:

• mmc1.pdf

View BVdb publication page

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Case report: Acquired neurotrophic tyrosine receptor kinase inhibitor resistance in a patient with pancreatic neuroendocrine carcinoma receiving entrectinib.

Frontiers In Oncology

Wu, Wen-Chi WC; Chen, Ming-Huang MH

Publication Date: 2022

Variant appearance in text: KRAS: Q61R

PubMed Link: 36703785

Variant Present in the following documents:

• Main text
• fonc-12-1031396.pdf

View BVdb publication page

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Evolution of acquired resistance in a ROS1+ KRAS G12C+ NSCLC through the MAPK pathway.

Npj Precision Oncology

Priest, Katherine K; Le, Anh A; Gebregzabheir, Amanuail A; Nijmeh, Hala H; Reis, Gregory B GB; Mandell, Melanie M; Davies, Kurtis D KD; Lawrence, Carolyn C; O'Donnell, Emily E; Doebele, Robert C RC; Bao, Liming L; Aisner, Dara L DL; Schenk, Erin L EL

Publication Date: 2023-01-23

Variant appearance in text: KRAS: Q61R

PubMed Link: 36690705

Variant Present in the following documents:

• Main text
• 41698_2023_Article_349.pdf

View BVdb publication page

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A phase II trial of GSK2256098 and trametinib in patients with advanced pancreatic ductal adenocarcinoma.

Journal Of Gastrointestinal Oncology

Aung, Kyaw L KL; McWhirter, Elaine E; Welch, Stephen S; Wang, Lisa L; Lovell, Sophia S; Stayner, Lee-Anne LA; Ali, Saara S; Malpage, Anne A; Makepeace, Barbara B; Ramachandran, Makilpriya M; Jang, Gun Ho GH; Gallinger, Steven S; Zhang, Tong T; Stockley, Tracy L TL; Fischer, Sandra E SE; Dhani, Neesha N; Hedley, David D; Knox, Jennifer J JJ; Siu, Lillian L LL; Goodwin, Rachel R; Bedard, Philippe L PL

Publication Date: 2022-12

Variant appearance in text: KRAS: Q61R

PubMed Link: 36636049

Variant Present in the following documents:

• Main text
• jgo-13-06-3216.pdf

View BVdb publication page

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Dynamic regulation of RAS and RAS signaling.

The Biochemical Journal

Kolch, Walter W; Berta, Dénes D; Rosta, Edina E

Publication Date: 2023-01-13

Variant appearance in text: KRAS: Q61R

PubMed Link: 36607281

Variant Present in the following documents:

• Main text
• BCJ-480-1.pdf

View BVdb publication page

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Preclinical Models of Follicular Cell-Derived Thyroid Cancer: An Overview from Cancer Cell Lines to Mouse Models.

Endocrinology And Metabolism (Seoul, Korea)

Jeon, Min Ji MJ; Haugen, Bryan R BR

Publication Date: 2022-12

Variant appearance in text: KRAS: Q61R

PubMed Link: 36604954

Variant Present in the following documents:

• enm-2022-1636.pdf

View BVdb publication page

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Clinical utility of Todai OncoPanel in the setting of approved comprehensive cancer genomic profiling tests in Japan.

Cancer Science

Kage, Hidenori H; Shinozaki-Ushiku, Aya A; Ishigaki, Kazunaga K; Sato, Yusuke Y; Tanabe, Masahiko M; Tanaka, Shota S; Tanikawa, Michihiro M; Watanabe, Kousuke K; Kato, Shingo S; Akagi, Kiwamu K; Uchino, Keita K; Mitani, Kinuko K; Takahashi, Shunji S; Miura, Yuji Y; Ikeda, Sadakatsu S; Kojima, Yasushi Y; Watanabe, Kiyotaka K; Mochizuki, Hitoshi H; Yamaguchi, Hironori H; Kawazoe, Yoshimasa Y; Kashiwabara, Kosuke K; Kohsaka, Shinji S; Tatsuno, Kenji K; Ushiku, Tetsuo T; Ohe, Kazuhiko K; Yatomi, Yutaka Y; Seto, Yasuyuki Y; Aburatani, Hiroyuki H; Mano, Hiroyuki H; Miyagawa, Kiyoshi K; Oda, Katsutoshi K

Publication Date: 2023-01-05

Variant appearance in text: KRAS: 182A>G; Q61R

PubMed Link: 36601953

Variant Present in the following documents:

• CAS-114-1710-s001.xlsx, sheet 1

View BVdb publication page

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Prognostic value of KRAS subtype in patients with PDAC undergoing radical resection.

Frontiers In Oncology

Dai, Manxiong M; Jahanzaib, Raja R; Liao, Yan Y; Yao, Fengxuan F; Li, Jia J; Teng, Xiong X; Chen, Kang K; Cheng, Wei W

Publication Date: 2022

Variant appearance in text: KRAS: Q61R

PubMed Link: 36582783

Variant Present in the following documents:

• Main text
• fonc-12-1074538.pdf

View BVdb publication page

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Tumor genomic profiling and personalized tracking of circulating tumor DNA in Vietnamese colorectal cancer patients.

Frontiers In Oncology

Nguyen, Huu Thinh HT; Nguyen, Trieu Vu TV; Nguyen Hoang, Van-Anh VA; Tran, Duc Huy DH; Le Trinh, Ngoc An NA; Le, Minh Triet MT; Nguyen Tran, Tuan-Anh TA; Pham, Thanh Huyen TH; Dinh, Thi Cuc TC; Nguyen, Tien Sy TS; Nguyen The, Ky Cuong KC; Mai, Hoa H; Chu, Minh Tuan MT; Pham, Dinh Hoang DH; Nguyen, Xuan Chi XC; Ngo Ha, Thien My TM; Nguyen, Duy Sinh DS; Nguyen, Du Quyen DQ; Lu, Y-Thanh YT; Do Thi, Thanh Thuy TT; Truong, Dinh Kiet DK; Nguyen, Quynh Tho QT; Nguyen, Hoai-Nghia HN; Giang, Hoa H; Tu, Lan N LN

Publication Date: 2022

Variant appearance in text: KRAS: Q61R

PubMed Link: 36578946

Variant Present in the following documents:

• DataSheet_1.pdf

View BVdb publication page

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Metastatic colorectal cancer treatment response evaluation by ultra-deep sequencing of cell-free DNA and matched white blood cells.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

van 't Erve, Iris I; Medina, Jamie E JE; Leal, Alessandro A; Papp, Eniko E; Phallen, Jillian J; Adleff, Vilmos V; Chiao, Elaine Jiayuee EJ; Arun, Adith S AS; Bolhuis, Karen K; Simmons, John K JK; Karandikar, Aanavi A; Valkenburg, Kenneth C KC; Sausen, Mark M; Angiuoli, Samuel V SV; Scharpf, Robert B RB; Punt, Cornelis J A CJA; Meijer, Gerrit A GA; Velculescu, Victor E VE; Fijneman, Remond J A RJA

Publication Date: 2022-12-19

Variant appearance in text: KRAS: Q61R

PubMed Link: 36534496

Variant Present in the following documents:

• ccr-22-2538_supplementary_tables_s1-s15_suppts1-ts15.xlsx, sheet 7

View BVdb publication page

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Advantages and Limitations of Monitoring Circulating Tumor DNA Levels to Predict the Prognosis of Patients Diagnosed With Gastric Cancer.

Biomarker Insights

He, Wan W; Yang, Jingxin J; Sun, Xiao X; Jiang, Shunda S; Jiang, Jinchan J; Liu, Ming M; Mu, Tianhao T; Li, Yingmei Y; Zhang, Xiaoni X; Duan, Jingxian J; Xu, Ruilian R

Publication Date: 2022

Variant appearance in text: KRAS: 182A>G; Q61R

PubMed Link: 36533271

Variant Present in the following documents:

• sj-xlsx-2-bmi-10.1177_11772719221141525.xlsx, sheet 1

View BVdb publication page

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Implantation of sigmoid colon cancer into the endoscopic resection site of intramucosal rectal cancer: A case report.

Den Open

Nishino, Kyohei K; Hongo, Masanori M; Mori, Naoko N; Shimamoto, Kazumi K; Kobayashi, Yu Y; Nakamura, Fumiyasu F; Hino, Michiko M; Togawa, Takeshi T; Andoh, Akira A; Ban, Hiromitsu H

Publication Date: 2023-04

Variant appearance in text: KRAS: Q61R

PubMed Link: 36514801

Variant Present in the following documents:

• Main text
• DEO2-3-e193.pdf

View BVdb publication page

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: KRAS: 182A>G; Q61R

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 3
• Table_2.xlsx, sheet 2

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Concordance Between Recommendations From Multidisciplinary Molecular Tumor Boards and Central Consensus for Cancer Treatment in Japan.

Jama Network Open

Naito, Yoichi Y; Sunami, Kuniko K; Kage, Hidenori H; Komine, Keigo K; Amano, Toraji T; Imai, Mitsuho M; Koyama, Takafumi T; Ennishi, Daisuke D; Kanai, Masashi M; Kenmotsu, Hirotsugu H; Maeda, Takahiro T; Morita, Sachi S; Sakai, Daisuke D; Watanabe, Kousuke K; Shirota, Hidekazu H; Kinoshita, Ichiro I; Yoshioka, Masashiro M; Mamesaya, Nobuaki N; Ito, Mamoru M; Kohsaka, Shinji S; Saigusa, Yusuke Y; Yamamoto, Kouji K; Hirata, Makoto M; Tsuchihara, Katsuya K; Yoshino, Takayuki T

Publication Date: 2022-12-01

Variant appearance in text: KRAS: Q61R

PubMed Link: 36469316

Variant Present in the following documents:

• Main text

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Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Cheng, Wen-Yan WY; Li, Jian-Feng JF; Zhu, Yong-Mei YM; Lin, Xiang-Jie XJ; Wen, Li-Jun LJ; Zhang, Fan F; Zhang, Yu-Liang YL; Zhao, Ming M; Fang, Hai H; Wang, Sheng-Yue SY; Lin, Xiao-Jing XJ; Qiao, Niu N; Yin, Wei W; Zhang, Jia-Nan JN; Dai, Yu-Ting YT; Jiang, Lu L; Sun, Xiao-Jian XJ; Xu, Yi Y; Zhang, Tong-Tong TT; Chen, Su-Ning SN; Zhu, Hong-Hu HH; Chen, Zhu Z; Jin, Jie J; Wu, De-Pei DP; Shen, Yang Y; Chen, Sai-Juan SJ

Publication Date: 2022-12-06

Variant appearance in text: KRAS: Q61R

PubMed Link: 36442087

Variant Present in the following documents:

• pnas.2211429119.sd02.xlsx, sheet 1
• pnas.2211429119.sapp.pdf

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Proteogenomic insights into the biology and treatment of pancreatic ductal adenocarcinoma.

Journal Of Hematology & Oncology

Tong, Yexin Y; Sun, Mingjun M; Chen, Lingli L; Wang, Yunzhi Y; Li, Yan Y; Li, Lingling L; Zhang, Xuan X; Cai, Yumeng Y; Qie, Jingbo J; Pang, Yanrui Y; Xu, Ziyan Z; Zhao, Jiangyan J; Zhang, Xiaolei X; Liu, Yang Y; Tian, Sha S; Qin, Zhaoyu Z; Feng, Jinwen J; Zhang, Fan F; Zhu, Jiajun J; Xu, Yifan Y; Lou, Wenhui W; Ji, Yuan Y; Zhao, Jianyuan J; He, Fuchu F; Hou, Yingyong Y; Ding, Chen C

Publication Date: 2022-11-25

Variant appearance in text: KRAS: Q61R

PubMed Link: 36434634

Variant Present in the following documents:

• Main text
• 13045_2022_1384_MOESM4_ESM.pdf
• 13045_2022_Article_1384.pdf

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: KRAS: Q61R

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

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KRAS mutation predict response and outcome in advanced non-small cell lung carcinoma without driver alterations receiving PD-1 blockade immunotherapy combined with platinum-based chemotherapy: a retrospective cohort study from China.

Translational Lung Cancer Research

Li, Qianni Q; Zhou, Qi Q; Zhao, Shicai S; Wu, Peng P; Shi, Ping P; Zeng, Jia J; Xiong, Xiaomin X; Chen, Haiwen H; Kittaneh, Muaiad M; Bravaccini, Sara S; Zanoni, Michele M; Zhou, Chengzhi C; Zhang, Jiexia J

Publication Date: 2022-10

Variant appearance in text: KRAS: Q61R

PubMed Link: 36386464

Variant Present in the following documents:

• Main text
• tlcr-11-10-2136.pdf

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Mitomycin C in Homologous Recombination Deficient Metastatic Pancreatic Cancer after Disease Progression on Platinum-Based Chemotherapy and Olaparib.

Biomedicines

Botrus, Gehan G; Roe, Denise D; Jameson, Gayle S GS; Junior, Pedro Luiz Serrano Uson PLSU; Korn, Ronald Lee RL; Caldwell, Lana L; Bargenquast, Taylor T; Miller, Max M; Borazanci, Erkut Hasan EH

Publication Date: 2022-10-26

Variant appearance in text: KRAS: Q61R

PubMed Link: 36359225

Variant Present in the following documents:

• Main text
• biomedicines-10-02705.pdf

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NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.

Cell Reports

Ramakrishnan, Gopalakrishnan G; Parajuli, Parash P; Singh, Pura P; Friend, Creighton C; Hurwitz, Eric E; Prunier, Celine C; Razzaque, Mohammed S MS; Xu, Keli K; Atfi, Azeddine A

Publication Date: 2022-11-08

Variant appearance in text: KRAS: 182A>G; Q61R

PubMed Link: 36351408

Variant Present in the following documents:

• NIHMS1848910-supplement-2.xlsx, sheet 1
• NIHMS1848910-supplement-2.xlsx, sheet 3

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Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa.

Bmc Cancer

Jafari, Meryem M; Laraqui, Abdelilah A; Baba, Walid W; Benmokhtar, Soukaina S; Zaitouni, Sara El SE; Ali, Abdelmounaim Ait AA; Bounaim, Ahmed A; Moujahid, Mountassir M; Tanz, Rachid R; Mahfoud, Tarik T; Sbitti, Yassir Y; Annaz, Hicham El HE; Abi, Rachid R; Tagajdid, Mohamed Rida MR; Kochri, Safae El SE; Lahlou, Idriss Amine IA; Hsaini, Houda El HE; Belayachi, Lamiae L; Benjouad, Abdelaziz A; Ichou, Mohammed M; En-Nya, Amina A; Ennibi, Khalid K

Publication Date: 2022-11-07

Variant appearance in text: KRAS: 182A>G; Q61R

PubMed Link: 36344948

Variant Present in the following documents:

• Main text
• 12885_2022_Article_10235.pdf

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Integrated proteogenomic characterization of medullary thyroid carcinoma.

Cell Discovery

Shi, Xiao X; Sun, Yaoting Y; Shen, Cenkai C; Zhang, Yan Y; Shi, Rongliang R; Zhang, Fan F; Liao, Tian T; Lv, Guojun G; Zhu, Zhengcai Z; Jiao, Lianghe L; Li, Peng P; Xu, Tiansheng T; Qu, Ning N; Huang, Naisi N; Hu, Jiaqian J; Zhang, Tingting T; Gu, Yanzi Y; Qin, Guangqi G; Guan, Haixia H; Pu, Weilin W; Li, Yuan Y; Geng, Xiang X; Zhang, Yan Y; Chen, Tongzhen T; Huang, Shenglin S; Zhang, Zhikang Z; Ge, Shuting S; Wang, Wu W; Xu, Weibo W; Yu, Pengcheng P; Lu, Zhongwu Z; Wang, Yulong Y; Guo, Liang L; Wang, Yu Y; Guo, Tiannan T; Ji, Qinghai Q; Wei, Wenjun W

Publication Date: 2022-11-08

Variant appearance in text: KRAS: Q61R; rs121913240

PubMed Link: 36344509

Variant Present in the following documents:

• 41421_2022_479_MOESM4_ESM.xlsx, sheet 2

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Uterine lavage identifies cancer mutations and increased TP53 somatic mutation burden in individuals with ovarian cancer.

Cancer Research Communications

Ghezelayagh, Talayeh S TS; Kohrn, Brendan F BF; Fredrickson, Jeanne J; Manhardt, Enna E; Radke, Marc R MR; Katz, Ronit R; Gray, Heidi J HJ; Urban, Renata R RR; Pennington, Kathryn P KP; Liao, John B JB; Doll, Kemi M KM; Simons, Elise J EJ; Burzawa, Jennifer K JK; Goff, Barbara A BA; Speiser, Paul P; Swisher, Elizabeth M EM; Norquist, Barbara M BM; Risques, Rosa Ana RA

Publication Date: 2022-10

Variant appearance in text: KRAS: 182A>G; Q61R

PubMed Link: 36311816

Variant Present in the following documents:

• crc-22-0314-s02.xlsx, sheet 6

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Genomic characterization reveals distinct mutation landscapes and therapeutic implications in neuroendocrine carcinomas of the gastrointestinal tract.

Cancer Communications (London, England)

Wu, Huanwen H; Yu, Zicheng Z; Liu, Yueping Y; Guo, Lei L; Teng, Lianghong L; Guo, Lingchuan L; Liang, Li L; Wang, Jing J; Gao, Jie J; Li, Ruiyu R; Yang, Ling L; Nie, Xiu X; Su, Dan D; Liang, Zhiyong Z

Publication Date: 2022-10-20

Variant appearance in text: KRAS: 182A>G; Q61R; rs121913240

PubMed Link: 36264285

Variant Present in the following documents:

• CAC2-42-1367-s002.xlsx, sheet 3

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Molecular targeted therapy for anticancer treatment.

Experimental & Molecular Medicine

Min, Hye-Young HY; Lee, Ho-Young HY

Publication Date: 2022-10

Variant appearance in text: KRAS: Q61R

PubMed Link: 36224343

Variant Present in the following documents:

• Main text
• 12276_2022_Article_864.pdf

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Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma.

Blood

Ansari-Pour, Naser N; Samur, Mehmet K MK; Flynt, Erin E; Gooding, Sarah S; Towfic, Fadi F; Stong, Nicholas N; Ortiz Estevez, Maria M; Mavrommatis, Konstantinos K; Walker, Brian A BA; Morgan, Gareth J GJ; Munshi, Nikhil C NC; Avet Loiseau, Herve H; Thakurta, Anjan A

Publication Date: 2022-10-12

Variant appearance in text: KRAS: Q61R

PubMed Link: 36223594

Variant Present in the following documents:

• BLOOD_BLD-2022-017010-mmc2.xlsx, sheet 1

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