KRAS c.175G>A ;(p.A59T)

Variant ID: 12-25380283-C-T

NM_004985.3(KRAS):c.175G>A;(p.A59T)

This variant was identified in 189 publications

View GRCh38 version.




Publications:


Is adagrasib just another sotorasib?-or, should we differentiate their usage according to patients' clinical presentation?

Translational Lung Cancer Research
Oya, Yuko Y; Mitsudomi, Tetsuya T
Publication Date: 2023-05-31

Variant appearance in text: KRAS: A59T
PubMed Link: 37323182
Variant Present in the following documents:
  • Main text
  • tlcr-12-05-940.pdf
View BVdb publication page



Recent Advances in Covalent Drug Discovery.

Pharmaceuticals (Basel, Switzerland)
Schaefer, Daniel D; Cheng, Xinlai X
Publication Date: 2023-04-28

Variant appearance in text: KRAS: A59T
PubMed Link: 37242447
Variant Present in the following documents:
  • Main text
  • pharmaceuticals-16-00663.pdf
View BVdb publication page



Targeting small GTPases: emerging grasps on previously untamable targets, pioneered by KRAS.

Signal Transduction And Targeted Therapy
Yin, Guowei G; Huang, Jing J; Petela, Johnny J; Jiang, Hongmei H; Zhang, Yuetong Y; Gong, Siqi S; Wu, Jiaxin J; Liu, Bei B; Shi, Jianyou J; Gao, Yijun Y
Publication Date: 2023-05-23

Variant appearance in text: KRAS: A59T
PubMed Link: 37221195
Variant Present in the following documents:
  • Main text
  • 41392_2023_Article_1441.pdf
View BVdb publication page



Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.

Biorxiv : The Preprint Server For Biology
Ratnasinghe, Brian D BD; Haque, Neshatul N; Wagenknecht, Jessica B JB; Jensen, Davin R DR; Esparza, Guadalupe V GV; Leverence, Elise N EN; De Assuncao, Thiago Milech TM; Mathison, Angela J AJ; Lomberk, Gwen G; Smith, Brian C BC; Volkman, Brian F BF; Urrutia, Raul R; Zimmermann, Michael T MT
Publication Date: 2023-04-28

Variant appearance in text: KRAS: A59T
PubMed Link: 37207265
Variant Present in the following documents:
  • Main text
  • nihpp-2023.04.28.536249v1.pdf
View BVdb publication page



Analysis of Circulating Tumor DNA in Synchronous Metastatic Colorectal Cancer at Diagnosis Predicts Overall Patient Survival.

International Journal Of Molecular Sciences
Sayagués, José María JM; Montero, Juan Carlos JC; Jiménez-Pérez, Andrea A; Del Carmen, Sofía S; Rodríguez, Marta M; Vidal Tocino, Rosario R; Montero, Enrique E; Sanz, Julia J; Abad, Mar M
Publication Date: 2023-05-08

Variant appearance in text: KRAS: A59T
PubMed Link: 37176143
Variant Present in the following documents:
  • ijms-24-08438.pdf
View BVdb publication page



Direct GDP-KRASG12C inhibitors and mechanisms of resistance: the tip of the iceberg.

Therapeutic Advances In Medical Oncology
Rosen, Joshua C JC; Sacher, Adrian A; Tsao, Ming-Sound MS
Publication Date: 2023

Variant appearance in text: KRAS: A59T
PubMed Link: 36950276
Variant Present in the following documents:
  • Main text
  • 10.1177_17588359231160141.pdf
View BVdb publication page



KRAS, NRAS, BRAF, HER2 and MSI Status in a Large Consecutive Series of Colorectal Carcinomas.

International Journal Of Molecular Sciences
Martianov, Aleksandr S AS; Mitiushkina, Natalia V NV; Ershova, Anastasia N AN; Martynenko, Darya E DE; Bubnov, Mikhail G MG; Amankwah, Priscilla P; Yanus, Grigory A GA; Aleksakhina, Svetlana N SN; Tiurin, Vladislav I VI; Venina, Aigul R AR; Anuskina, Aleksandra A AA; Gorgul, Yuliy A YA; Shestakova, Anna D AD; Maidin, Mikhail A MA; Belyaev, Alexey M AM; Baboshkina, Liliya S LS; Iyevleva, Aglaya G AG; Imyanitov, Evgeny N EN
Publication Date: 2023-03-02

Variant appearance in text: KRAS: A59T
PubMed Link: 36902296
Variant Present in the following documents:
  • Main text
  • ijms-24-04868.pdf
View BVdb publication page



Targeted therapies for KRAS-mutant non-small cell lung cancer: from preclinical studies to clinical development-a narrative review.

Translational Lung Cancer Research
Santarpia, Mariacarmela M; Ciappina, Giuliana G; Spagnolo, Calogera Claudia CC; Squeri, Andrea A; Passalacqua, Maria Ilenia MI; Aguilar, Andrés A; Gonzalez-Cao, Maria M; Giovannetti, Elisa E; Silvestris, Nicola N; Rosell, Rafael R
Publication Date: 2023-02-28

Variant appearance in text: KRAS: A59T
PubMed Link: 36895930
Variant Present in the following documents:
  • Main text
  • tlcr-12-02-346.pdf
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: KRAS: 175G>A; Ala59Thr
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



KRAS Mutations in Solid Tumors: Characteristics, Current Therapeutic Strategy, and Potential Treatment Exploration.

Journal Of Clinical Medicine
Yang, Yunkai Y; Zhang, Huan H; Huang, Shanshan S; Chu, Qian Q
Publication Date: 2023-01-16

Variant appearance in text: KRAS: A59T
PubMed Link: 36675641
Variant Present in the following documents:
  • Main text
  • jcm-12-00709.pdf
View BVdb publication page



Targeting KRAS G12C mutations in colorectal cancer.

Gastroenterology Report
Zhao, Ming-He MH; Wu, Ai-Wen AW
Publication Date: 2023

Variant appearance in text: KRAS: A59T
PubMed Link: 36632627
Variant Present in the following documents:
  • Main text
  • goac083.pdf
View BVdb publication page



Targeting of colorectal cancer organoids with zoledronic acid conjugated to the anti-EGFR antibody cetuximab.

Journal For Immunotherapy Of Cancer
Benelli, Roberto R; Costa, Delfina D; Salvini, Laura L; Tardito, Samuele S; Tosetti, Francesca F; Villa, Federico F; Zocchi, Maria Raffaella MR; Poggi, Alessandro A
Publication Date: 2022-12

Variant appearance in text: KRAS: A59T
PubMed Link: 36543375
Variant Present in the following documents:
  • jitc-2022-005660supp001.pdf
View BVdb publication page



Mutations matter: An observational study of the prognostic and predictive value of KRAS mutations in metastatic colorectal cancer.

Frontiers In Oncology
Lavacchi, Daniele D; Fancelli, Sara S; Roviello, Giandomenico G; Castiglione, Francesca F; Caliman, Enrico E; Rossi, Gemma G; Venturini, Jacopo J; Pellegrini, Elisa E; Brugia, Marco M; Vannini, Agnese A; Bartoli, Caterina C; Cianchi, Fabio F; Pillozzi, Serena S; Antonuzzo, Lorenzo L
Publication Date: 2022

Variant appearance in text: KRAS: A59T
PubMed Link: 36523988
Variant Present in the following documents:
  • Main text
  • fonc-12-1055019.pdf
View BVdb publication page



Whole-Exome Sequencing Among Chinese Patients With Hereditary Diffuse Gastric Cancer.

Jama Network Open
Liu, Ze-Xian ZX; Zhang, Xiao-Long XL; Zhao, Qi Q; Chen, Yungchang Y; Sheng, Hui H; He, Cai-Yun CY; Sun, Yu-Ting YT; Lai, Ming-Yu MY; Wu, Min-Qing MQ; Zuo, Zhi-Xiang ZX; Wang, Wei W; Zhou, Zhi-Wei ZW; Wang, Feng-Hua FH; Li, Yu-Hong YH; Xu, Rui-Hua RH; Qiu, Miao-Zhen MZ
Publication Date: 2022-12-01

Variant appearance in text: KRAS: A59T
PubMed Link: 36484990
Variant Present in the following documents:
  • jamanetwopen-e2245836-s002.xlsx, sheet 3
View BVdb publication page



How to manage KRAS G12C-mutated advanced non-small-cell lung cancer.

Drugs In Context
Ricciuti, Biagio B; Mira, Alessia A; Andrini, Elisa E; Scaparone, Pietro P; Michelina, Sandra Vietti SV; Pecci, Federica F; Cantini, Luca L; De Giglio, Andrea A; Lamberti, Giuseppe G; Ambrogio, Chiara C; Metro, Giulio G
Publication Date: 2022

Variant appearance in text: KRAS: A59T
PubMed Link: 36452878
Variant Present in the following documents:
  • Main text
  • dic-2022-7-4.pdf
View BVdb publication page



Transcriptome-based molecular subtypes and differentiation hierarchies improve the classification framework of acute myeloid leukemia.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Cheng, Wen-Yan WY; Li, Jian-Feng JF; Zhu, Yong-Mei YM; Lin, Xiang-Jie XJ; Wen, Li-Jun LJ; Zhang, Fan F; Zhang, Yu-Liang YL; Zhao, Ming M; Fang, Hai H; Wang, Sheng-Yue SY; Lin, Xiao-Jing XJ; Qiao, Niu N; Yin, Wei W; Zhang, Jia-Nan JN; Dai, Yu-Ting YT; Jiang, Lu L; Sun, Xiao-Jian XJ; Xu, Yi Y; Zhang, Tong-Tong TT; Chen, Su-Ning SN; Zhu, Hong-Hu HH; Chen, Zhu Z; Jin, Jie J; Wu, De-Pei DP; Shen, Yang Y; Chen, Sai-Juan SJ
Publication Date: 2022-12-06

Variant appearance in text: KRAS: 175G>A; Ala59Thr
PubMed Link: 36442087
Variant Present in the following documents:
  • pnas.2211429119.sd02.xlsx, sheet 1
View BVdb publication page



A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.

The Lancet. Haematology
,
Publication Date: 2022-11-24

Variant appearance in text: KRAS: 175G>A; A59T
PubMed Link: 36436542
Variant Present in the following documents:
  • mmc2.xlsx, sheet 1
View BVdb publication page



Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications
Boström, Martin M; Larsson, Erik E
Publication Date: 2022-11-17

Variant appearance in text: KRAS: A59T
PubMed Link: 36396655
Variant Present in the following documents:
  • 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Prevalence and patterns of mutations in RAS/RAF/MEK/ERK/MAPK signaling pathway in colorectal cancer in North Africa.

Bmc Cancer
Jafari, Meryem M; Laraqui, Abdelilah A; Baba, Walid W; Benmokhtar, Soukaina S; Zaitouni, Sara El SE; Ali, Abdelmounaim Ait AA; Bounaim, Ahmed A; Moujahid, Mountassir M; Tanz, Rachid R; Mahfoud, Tarik T; Sbitti, Yassir Y; Annaz, Hicham El HE; Abi, Rachid R; Tagajdid, Mohamed Rida MR; Kochri, Safae El SE; Lahlou, Idriss Amine IA; Hsaini, Houda El HE; Belayachi, Lamiae L; Benjouad, Abdelaziz A; Ichou, Mohammed M; En-Nya, Amina A; Ennibi, Khalid K
Publication Date: 2022-11-07

Variant appearance in text: KRAS: 175G>A; Ala59Thr
PubMed Link: 36344948
Variant Present in the following documents:
  • Main text
  • 12885_2022_Article_10235.pdf
View BVdb publication page



Analytical and clinical validation of a custom 15-gene next-generation sequencing panel for the evaluation of circulating tumor DNA mutations in patients with advanced non-small-cell lung cancer.

Plos One
Chow, Yock Ping YP; Zainul Abidin, Norziha N; Kow, Ken Siong KS; Tho, Lye Mun LM; Wong, Chieh Lee CL
Publication Date: 2022

Variant appearance in text: KRAS: Ala59Thr
PubMed Link: 36256645
Variant Present in the following documents:
  • pone.0276161.s002.xlsx, sheet 1
View BVdb publication page



Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia.

Hemasphere
Pilheden, Mattias M; Ahlgren, Louise L; Hyrenius-Wittsten, Axel A; Gonzalez-Pena, Veronica V; Sturesson, Helena H; Hansen Marquart, Hanne Vibeke HV; Lausen, Birgitte B; Castor, Anders A; Pronk, Cornelis Jan CJ; Barbany, Gisela G; Pokrovskaja Tamm, Katja K; Fogelstrand, Linda L; Lohi, Olli O; Norén-Nyström, Ulrika U; Asklin, Johanna J; Chen, Yilun Y; Song, Guangchun G; Walsh, Michael M; Ma, Jing J; Zhang, Jinghui J; Saal, Lao H LH; Gawad, Charles C; Hagström-Andersson, Anna K AK
Publication Date: 2022-10

Variant appearance in text: KRAS: A59T
PubMed Link: 36204688
Variant Present in the following documents:
  • hs9-6-e785-s001.xlsx, sheet 6
View BVdb publication page



Molecular Biology and Therapeutic Perspectives for K-Ras Mutant Non-Small Cell Lung Cancers.

Cancers
Cekani, Elona E; Epistolio, Samantha S; Dazio, Giulia G; Cefalì, Marco M; Wannesson, Luciano L; Frattini, Milo M; Froesch, Patrizia P
Publication Date: 2022-08-24

Variant appearance in text: KRAS: 175G>A; A59T
PubMed Link: 36077640
Variant Present in the following documents:
  • cancers-14-04103.pdf
View BVdb publication page



Conquering oncogenic KRAS and its bypass mechanisms.

Theranostics
Hou, Pingping P; Wang, Y Alan YA
Publication Date: 2022

Variant appearance in text: KRAS: A59T
PubMed Link: 35966590
Variant Present in the following documents:
  • Main text
  • thnov12p5691.pdf
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: KRAS: 175G>A; A59T
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



Prognostic Value of KRAS Mutations in Colorectal Cancer Patients.

Cancers
Koulouridi, Asimina A; Karagianni, Michaela M; Messaritakis, Ippokratis I; Sfakianaki, Maria M; Voutsina, Alexandra A; Trypaki, Maria M; Bachlitzanaki, Maria M; Koustas, Evangelos E; Karamouzis, Michalis V MV; Ntavatzikos, Anastasios A; Koumarianou, Anna A; Androulakis, Nikolaos N; Mavroudis, Dimitrios D; Tzardi, Maria M; Souglakos, John J
Publication Date: 2022-07-07

Variant appearance in text: KRAS: A59T
PubMed Link: 35884381
Variant Present in the following documents:
  • cancers-14-03320.pdf
View BVdb publication page



Mucoepidermoid carcinoma (MEC) and adenosquamous carcinoma (ASC), the same or different entities?

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc
White, Valerie A VA; Hyrcza, Martin D MD; Lennerz, Jochen K JK; Thierauf, Julia J; Lokuhetty, Dilani D; Cree, Ian A IA; Indave, Blanca Iciar BI
Publication Date: 2022-10

Variant appearance in text: KRAS: 175G>A; A59T
PubMed Link: 35871081
Variant Present in the following documents:
  • 41379_2022_1100_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Analysis of KRAS, NRAS, and BRAF Mutations, Microsatellite Instability, and Relevant Prognosis Effects in Patients With Early Colorectal Cancer: A Cohort Study in East Asia.

Frontiers In Oncology
Li, Yang Y; Xiao, Jun J; Zhang, Tiancheng T; Zheng, Yanying Y; Jin, Hailin H
Publication Date: 2022

Variant appearance in text: KRAS: A59T
PubMed Link: 35837115
Variant Present in the following documents:
  • Main text
  • fonc-12-897548.pdf
View BVdb publication page



IGH Translocations in Chinese Patients With Chronic Lymphocytic Leukemia: Clinicopathologic Characteristics and Genetic Profile.

Frontiers In Oncology
Li, Qinlu Q; Xing, Shugang S; Zhang, Heng H; Mao, Xiao X; Xiao, Min M; Wang, Ying Y
Publication Date: 2022

Variant appearance in text: rs121913528
PubMed Link: 35720006
Variant Present in the following documents:
  • Table_2.xlsx, sheet 1
View BVdb publication page



Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications
Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX
Publication Date: 2022-06-15

Variant appearance in text: KRAS: A59T
PubMed Link: 35705558
Variant Present in the following documents:
  • 41467_2022_30496_MOESM2_ESM.xls, sheet 1
View BVdb publication page



Rare presentation of multiple thromboses in Erdheim-Chester disease: a case-based review.

International Journal Of Hematology
Liu, Yongchang Y; Huang, Changpin C; Meng, Xiaohu X; Fang, Xin X; Xie, Xupin X; Wang, Changrong C; Wang, Meiyun M
Publication Date: 2022-11

Variant appearance in text: KRAS: A59T
PubMed Link: 35687294
Variant Present in the following documents:
  • Main text
  • 12185_2022_Article_3393.pdf
View BVdb publication page



High prevalence of unusual KRAS, NRAS, and BRAF mutations in POLE-hypermutated colorectal cancers.

Molecular Oncology
Favre, Loetitia L; Cohen, Justine J; Calderaro, Julien J; Pécriaux, Adrien A; Nguyen, Cong-Trung CT; Bourgoin, Rémi R; Larnaudie, Laura L; Dupuy, Aurélie A; Ollier, Marie M; Lechapt, Emmanuèle E; Sloma, Ivan I; Tournigand, Christophe C; Rousseau, Benoit B; Pujals, Anaïs A
Publication Date: 2022-09

Variant appearance in text: KRAS: A59T
PubMed Link: 35624529
Variant Present in the following documents:
  • Main text
  • MOL2-16-3055.pdf
View BVdb publication page



Performance of Idylla™ RAS-BRAF mutation test for formalin-fixed paraffin-embedded tissues of colorectal cancer.

International Journal Of Clinical Oncology
Makutani, Yusuke Y; Sakai, Kazuko K; Yamada, Masahiro M; Wada, Toshiaki T; Chikugo, Takaaki T; Satou, Takao T; Iwasa, Yoko Y; Yamamoto, Hidekazu H; de Velasco, Marco A MA; Nishio, Kazuto K; Kawamura, Junichiro J
Publication Date: 2022-07

Variant appearance in text: KRAS: 175G>A
PubMed Link: 35474548
Variant Present in the following documents:
  • 10147_2022_2167_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



A stop-gain mutation in GXYLT1 promotes metastasis of colorectal cancer via the MAPK pathway.

Cell Death & Disease
Peng, Lin L; Zhao, Min M; Liu, Tianqi T; Chen, Jiangbo J; Gao, Pin P; Chen, Lei L; Xing, Pu P; Wang, Zaozao Z; Di, Jiabo J; Xu, Qiang Q; Qu, Hong H; Jiang, Beihai B; Su, Xiangqian X
Publication Date: 2022-04-22

Variant appearance in text: KRAS: A59T
PubMed Link: 35459861
Variant Present in the following documents:
  • 41419_2022_4844_MOESM4_ESM.xlsx, sheet 3
View BVdb publication page



The prevalence and real-world therapeutic analysis of Chinese patients with KRAS-Mutant Non-Small Cell lung cancer.

Cancer Medicine
Chen, Hanxiao H; Huang, Dingzhi D; Lin, Gen G; Yang, Xue X; Zhuo, Minglei M; Chi, Yujia Y; Zhai, Xiaoyu X; Jia, Bo B; Wang, Jingjing J; Wang, Yuyan Y; Li, Jianjie J; An, Tongtong T; Wu, Meina M; Wang, Ziping Z; Zhao, Jun J
Publication Date: 2022-10

Variant appearance in text: KRAS: A59T
PubMed Link: 35394121
Variant Present in the following documents:
  • Main text
  • CAM4-11-3581.pdf
View BVdb publication page



Circulating Tumor DNA Mutations in Progressive Gastrointestinal Stromal Tumors Identify Biomarkers of Treatment Resistance and Uncover Potential Therapeutic Strategies.

Frontiers In Oncology
Ko, Tun Kiat TK; Lee, Elizabeth E; Ng, Cedric Chuan-Young CC; Yang, Valerie Shiwen VS; Farid, Mohamad M; Teh, Bin Tean BT; Chan, Jason Yongsheng JY; Somasundaram, Nagavalli N
Publication Date: 2022

Variant appearance in text: KRAS: 175G>A
PubMed Link: 35273917
Variant Present in the following documents:
  • Main text
  • fonc-12-840843.pdf
View BVdb publication page



Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine
Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R
Publication Date: 2022-05

Variant appearance in text: KRAS: 175G>A; Ala59Thr
PubMed Link: 35244186
Variant Present in the following documents:
  • Supplementary_Data2.xlsx, sheet 1
  • Supplementary_Data3.xlsx, sheet 1
View BVdb publication page



Dynamics of RAS/BRAF Mutations in cfDNA from Metastatic Colorectal Carcinoma Patients Treated with Polychemotherapy and Anti-EGFR Monoclonal Antibodies.

Cancers
Rachiglio, Anna Maria AM; Forgione, Laura L; Pasquale, Raffaella R; Barone, Carlo Antonio CA; Maiello, Evaristo E; Antonuzzo, Lorenzo L; Cassata, Antonino A; Tonini, Giuseppe G; Bordonaro, Roberto R; Rosati, Gerardo G; Zaniboni, Alberto A; Lonardi, Sara S; Ferrari, Daris D; Frassineti, Giovanni Luca GL; Tamberi, Stefano S; Pisconti, Salvatore S; Di Fabio, Francesca F; Roma, Cristin C; Orlandi, Armando A; Latiano, Tiziana T; Damato, Angela A; Tortora, Giampaolo G; Pinto, Carmine C; Normanno, Nicola N
Publication Date: 2022-02-18

Variant appearance in text: KRAS: A59T
PubMed Link: 35205799
Variant Present in the following documents:
  • cancers-14-01052.pdf
View BVdb publication page



The genetic landscape of pancreatic head ductal adenocarcinoma in China and prognosis stratification.

Bmc Cancer
Yang, Yefan Y; Ding, Ying Y; Gong, Yuxi Y; Zhao, Sha S; Li, Mingna M; Li, Xiao X; Song, Guoxin G; Zhai, Boya B; Liu, Jin J; Shao, Yang Y; Zhu, Liuqing L; Pang, Jiaohui J; Ma, Yutong Y; Ou, Qiuxiang Q; Wu, Xue X; Zhang, Zhihong Z
Publication Date: 2022-02-18

Variant appearance in text: KRAS: 175G>A; A59T
PubMed Link: 35180847
Variant Present in the following documents:
  • 12885_2022_9279_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.

Nature Biotechnology
Sánchez-Rivera, Francisco J FJ; Diaz, Bianca J BJ; Kastenhuber, Edward R ER; Schmidt, Henri H; Katti, Alyna A; Kennedy, Margaret M; Tem, Vincent V; Ho, Yu-Jui YJ; Leibold, Josef J; Paffenholz, Stella V SV; Barriga, Francisco M FM; Chu, Kevan K; Goswami, Sukanya S; Wuest, Alexandra N AN; Simon, Janelle M JM; Tsanov, Kaloyan M KM; Chakravarty, Debyani D; Zhang, Hongxin H; Leslie, Christina S CS; Lowe, Scott W SW; Dow, Lukas E LE
Publication Date: 2022-06

Variant appearance in text: KRAS: A59T
PubMed Link: 35165384
Variant Present in the following documents:
  • NIHMS1760571-supplement-Supplementary_Table_S2.xlsx, sheet 4
  • NIHMS1760571-supplement-Supplementary_Table_S2.xlsx, sheet 6
  • NIHMS1760571-supplement-Supplementary_Table_S7.xlsx, sheet 5
View BVdb publication page



Circulating tumor DNA (ctDNA) serial analysis during progression on PD-1 blockade and later CTLA-4 rescue in patients with mismatch repair deficient metastatic colorectal cancer.

Journal For Immunotherapy Of Cancer
Kasi, Pashtoon Murtaza PM; Budde, Griffin G; Krainock, Michael M; Aushev, Vasily N VN; Koyen Malashevich, Allyson A; Malhotra, Meenakshi M; Olshan, Perry P; Billings, Paul R PR; Aleshin, Alexey A
Publication Date: 2022-01

Variant appearance in text: KRAS: A59T
PubMed Link: 35101943
Variant Present in the following documents:
  • Main text
View BVdb publication page



Circulating tumor DNA (ctDNA) serial analysis during progression on PD-1 blockade and later CTLA-4 rescue in patients with mismatch repair deficient metastatic colorectal cancer.

Journal For Immunotherapy Of Cancer
Kasi, Pashtoon Murtaza PM; Budde, Griffin G; Krainock, Michael M; Aushev, Vasily N VN; Koyen Malashevich, Allyson A; Malhotra, Meenakshi M; Olshan, Perry P; Billings, Paul R PR; Aleshin, Alexey A
Publication Date: 2022-01

Variant appearance in text: KRAS: A59T
PubMed Link: 35101943
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeting KRAS in Non-Small Cell Lung Cancer.

Frontiers In Oncology
Corral de la Fuente, Elena E; Olmedo Garcia, Maria Eugenia ME; Gomez Rueda, Ana A; Lage, Yolanda Y; Garrido, Pilar P
Publication Date: 2021

Variant appearance in text: KRAS: A59T
PubMed Link: 35083149
Variant Present in the following documents:
  • Main text
  • fonc-11-792635.pdf
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Sensitive Quantification of Cell-Free Tumor DNA for Early Detection of Recurrence in Colorectal Cancer.

Frontiers In Genetics
Stasik, Sebastian S; Mende, Marika M; Schuster, Caroline C; Mahler, Sandra S; Aust, Daniela D; Tannapfel, Andrea A; Reinacher-Schick, Anke A; Baretton, Gustavo G; Krippendorf, Claudia C; Bornhäuser, Martin M; Ehninger, Gerhard G; Folprecht, Gunnar G; Thiede, Christian C
Publication Date: 2021

Variant appearance in text: KRAS: 175G>A; Ala59Thr
PubMed Link: 35069704
Variant Present in the following documents:
  • Main text
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A Breakthrough Brought about by Targeting KRASG12C: Nonconformity Is Punished.

Cancers
Ning, Wenjuan W; Yang, Zhang Z; Kocher, Gregor J GJ; Dorn, Patrick P; Peng, Ren-Wang RW
Publication Date: 2022-01-13

Variant appearance in text: KRAS: A59T
PubMed Link: 35053550
Variant Present in the following documents:
  • Main text
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A Breakthrough Brought about by Targeting KRASG12C: Nonconformity Is Punished.

Cancers
Ning, Wenjuan W; Yang, Zhang Z; Kocher, Gregor J GJ; Dorn, Patrick P; Peng, Ren-Wang RW
Publication Date: 2022-01-13

Variant appearance in text: KRAS: A59T
PubMed Link: 35053550
Variant Present in the following documents:
  • Main text
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A Structure is Worth a Thousand Words: New Insights for RAS and RAF Regulation.

Cancer Discovery
Simanshu, Dhirendra K DK; Morrison, Deborah K DK
Publication Date: 2022-04-01

Variant appearance in text: KRAS: A59T
PubMed Link: 35046094
Variant Present in the following documents:
  • 899.pdf
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