Publications:

---

KRAS Mutations Are Associated with Shortened Survival in Patients with Epithelioid Malignant Pleural Mesothelioma.

Cancers

Vannucchi, Margherita M; Pennati, Veronica V; Mencaroni, Clelia C; Defraia, Chiara C; Bardhi, Ledi L; Castiglione, Francesca F; Bellan, Cristiana C; Comin, Camilla Eva CE

Publication Date: 2023-03-30

Variant appearance in text: KRAS: D57N

PubMed Link: 37046732

Variant Present in the following documents:

• Main text
• cancers-15-02072.pdf

View BVdb publication page

---

A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Jang, H Josh HJ; Hostetter, Galen G; MacFarlane, Alexander W AW; Madaj, Zachary Z; Ross, Eric A EA; Hinoue, Toshinori T; Kulchycki, Justin R JR; Burgos, Ryan S RS; Tafseer, Mahvish M; Alpaugh, R Katherine RK; Schwebel, Candice L CL; Kokate, Rutika R; Geynisman, Daniel M DM; Zibelman, Matthew R MR; Ghatalia, Pooja P; Nichols, Peter W PW; Chung, Woonbok W; Madzo, Jozef J; Hahn, Noah M NM; Quinn, David I DI; Issa, Jean-Pierre J JJ; Topper, Michael J MJ; Baylin, Stephen B SB; Shen, Hui H; Campbell, Kerry S KS; Jones, Peter A PA; Plimack, Elizabeth R ER

Publication Date: 2023-03-16

Variant appearance in text: KRAS: D57N

PubMed Link: 36928921

Variant Present in the following documents:

• ccr-22-3642_supplementary_tables_1_suppts1.xlsx, sheet 3

View BVdb publication page

---

High prevalence of unusual KRAS, NRAS, and BRAF mutations in POLE-hypermutated colorectal cancers.

Molecular Oncology

Favre, Loetitia L; Cohen, Justine J; Calderaro, Julien J; Pécriaux, Adrien A; Nguyen, Cong-Trung CT; Bourgoin, Rémi R; Larnaudie, Laura L; Dupuy, Aurélie A; Ollier, Marie M; Lechapt, Emmanuèle E; Sloma, Ivan I; Tournigand, Christophe C; Rousseau, Benoit B; Pujals, Anaïs A

Publication Date: 2022-09

Variant appearance in text: KRAS: D57N

PubMed Link: 35624529

Variant Present in the following documents:

• Main text
• MOL2-16-3055.pdf

View BVdb publication page

---

Genetic Alterations Predict Long-Term Survival in Ductal Adenocarcinoma of the Pancreatic Head.

Cancers

Safi, Sami-Alexander SA; Haeberle, Lena L; Goering, Wolfgang W; Keitel, Verena V; Fluegen, Georg G; Stoecklein, Nikolas N; Rehders, Alexander A; Knoefel, Wolfram Trudo WT; Esposito, Irene I

Publication Date: 2022-02-08

Variant appearance in text: KRAS: D57N

PubMed Link: 35159117

Variant Present in the following documents:

• Main text
• cancers-14-00850.pdf

View BVdb publication page

---

Genetic Alterations Predict Long-Term Survival in Ductal Adenocarcinoma of the Pancreatic Head.

Cancers

Safi, Sami-Alexander SA; Haeberle, Lena L; Goering, Wolfgang W; Keitel, Verena V; Fluegen, Georg G; Stoecklein, Nikolas N; Rehders, Alexander A; Knoefel, Wolfram Trudo WT; Esposito, Irene I

Publication Date: 2022-02-08

Variant appearance in text: KRAS: D57N

PubMed Link: 35159117

Variant Present in the following documents:

• Main text
• cancers-14-00850.pdf

View BVdb publication page

---

Clinical and Functional Characterization of Atypical KRAS/NRAS Mutations in Metastatic Colorectal Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Loree, Jonathan M JM; Wang, Yucai Y; Syed, Muddassir A MA; Sorokin, Alexey V AV; Coker, Oluwadara O; Xiu, Joanne J; Weinberg, Benjamin A BA; Vanderwalde, Ari M AM; Tesfaye, Anteneh A; Raymond, Victoria M VM; Miron, Benjamin B; Tarcic, Gabi G; Zelichov, Ori O; Broaddus, Russell R RR; Ng, Patrick Kwok Shing PKS; Jeong, Kang Jin KJ; Tsang, Yiu Huen YH; Mills, Gordon B GB; Overman, Michael J MJ; Grothey, Axel A; Marshall, John L JL; Kopetz, Scott S

Publication Date: 2021-08-15

Variant appearance in text: KRAS: D57N

PubMed Link: 34117033

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Standardization of Somatic Variant Classifications in Solid and Haematological Tumours by a Two-Level Approach of Biological and Clinical Classes: An Initiative of the Belgian ComPerMed Expert Panel.

Cancers

Froyen, Guy G; Le Mercier, Marie M; Lierman, Els E; Vandepoele, Karl K; Nollet, Friedel F; Boone, Elke E; Van der Meulen, Joni J; Jacobs, Koen K; Lambin, Suzan S; Vander Borght, Sara S; Van Valckenborgh, Els E; Antoniou, Aline A; Hébrant, Aline A

Publication Date: 2019-12-16

Variant appearance in text: KRAS: 169G>A; Asp57Asn

PubMed Link: 31888289

Variant Present in the following documents:

• Main text
• cancers-11-02030.pdf

View BVdb publication page

---

Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: KRAS: D57N

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 2
• pone.0196434.s001.xlsx, sheet 3
• pone.0196434.s001.xlsx, sheet 1

View BVdb publication page

---

Identification of Serine 119 as an Effective Inhibitor Binding Site of M. tuberculosis Ubiquitin-like Protein Ligase PafA Using Purified Proteins and M. smegmatis.

Ebiomedicine

Jiang, He-Wei HW; Czajkowsky, Daniel M DM; Wang, Tao T; Wang, Xu-De XD; Wang, Jia-Bin JB; Zhang, Hai-Nan HN; Liu, Cheng-Xi CX; Wu, Fan-Lin FL; He, Xiang X; Xu, Zhao-Wei ZW; Chen, Hong H; Guo, Shu-Juan SJ; Li, Yang Y; Bi, Li-Jun LJ; Deng, Jiao-Yu JY; Xie, Jin J; Pei, Jian-Feng JF; Zhang, Xian-En XE; Tao, Sheng-Ce SC

Publication Date: 2018-04

Variant appearance in text: KRAS: D57N

PubMed Link: 29622495

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

---

Integrating genomic alterations in diffuse large B-cell lymphoma identifies new relevant pathways and potential therapeutic targets.

Leukemia

Karube, K K; Enjuanes, A A; Dlouhy, I I; Jares, P P; Martin-Garcia, D D; Nadeu, F F; Ordóñez, G R GR; Rovira, J J; Clot, G G; Royo, C C; Navarro, A A; Gonzalez-Farre, B B; Vaghefi, A A; Castellano, G G; Rubio-Perez, C C; Tamborero, D D; Briones, J J; Salar, A A; Sancho, J M JM; Mercadal, S S; Gonzalez-Barca, E E; Escoda, L L; Miyoshi, H H; Ohshima, K K; Miyawaki, K K; Kato, K K; Akashi, K K; Mozos, A A; Colomo, L L; Alcoceba, M M; Valera, A A; Carrió, A A; Costa, D D; Lopez-Bigas, N N; Schmitz, R R; Staudt, L M LM; Salaverria, I I; López-Guillermo, A A; Campo, E E

Publication Date: 2018-03

Variant appearance in text: KRAS: 169G>A; D57N

PubMed Link: 28804123

Variant Present in the following documents:

• leu2017251x2.xlsx, sheet 3
• leu2017251x2.xlsx, sheet 4

View BVdb publication page

---

Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications

Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ

Publication Date: 2017-08-04

Variant appearance in text: KRAS: 169G>A; D57N

PubMed Link: 28775315

Variant Present in the following documents:

• 41467_2017_289_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

---

Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines.

Genome Medicine

Alfaro, Javier A JA; Ignatchenko, Alexandr A; Ignatchenko, Vladimir V; Sinha, Ankit A; Boutros, Paul C PC; Kislinger, Thomas T

Publication Date: 2017-07-18

Variant appearance in text: KRAS: D57N

PubMed Link: 28716134

Variant Present in the following documents:

• 13073_2017_454_MOESM7_ESM.xlsx, sheet 1
• 13073_2017_454_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

---

Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: KRAS: 169G>A

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

View BVdb publication page

---

Detection of oncogenic mutations in resected bronchial margins by next-generation sequencing indicates early relapse in stage IA lung adenocarcinoma patients.

Oncotarget

Lv, Tangfeng T; Zou, Jiawei J; Liu, Hongbing H; Shen, Qin Q; Lu, Zhenfeng Z; Zhou, XiaoJun X; Wang, Xiaonan X; Song, Yong Y

Publication Date: 2017-06-20

Variant appearance in text: KRAS: D57N

PubMed Link: 28380452

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Exome Sequencing Identifies Potentially Druggable Mutations in Nasopharyngeal Carcinoma.

Scientific Reports

Chow, Yock Ping YP; Tan, Lu Ping LP; Chai, San Jiun SJ; Abdul Aziz, Norazlin N; Choo, Siew Woh SW; Lim, Paul Vey Hong PV; Pathmanathan, Rajadurai R; Mohd Kornain, Noor Kaslina NK; Lum, Chee Lun CL; Pua, Kin Choo KC; Yap, Yoke Yeow YY; Tan, Tee Yong TY; Teo, Soo Hwang SH; Khoo, Alan Soo-Beng AS; Patel, Vyomesh V

Publication Date: 2017-03-03

Variant appearance in text: KRAS: D57N

PubMed Link: 28256603

Variant Present in the following documents:

• srep42980-s2.xls, sheet 9

View BVdb publication page

---

Mutational landscape reflects the biological continuum of plasma cell dyscrasias.

Blood Cancer Journal

Rossi, A A; Voigtlaender, M M; Janjetovic, S S; Thiele, B B; Alawi, M M; März, M M; Brandt, A A; Hansen, T T; Radloff, J J; Schön, G G; Hegenbart, U U; Schönland, S S; Langer, C C; Bokemeyer, C C; Binder, M M

Publication Date: 2017-02-24

Variant appearance in text: KRAS: 169G>A; D57N

PubMed Link: 28234344

Variant Present in the following documents:

• Main text

View BVdb publication page

---

LowMACA: exploiting protein family analysis for the identification of rare driver mutations in cancer.

Bmc Bioinformatics

Melloni, Giorgio E M GE; de Pretis, Stefano S; Riva, Laura L; Pelizzola, Mattia M; Céol, Arnaud A; Costanza, Jole J; Müller, Heiko H; Zammataro, Luca L

Publication Date: 2016-02-09

Variant appearance in text: KRAS: D57N

PubMed Link: 26860319

Variant Present in the following documents:

• 12859_2016_935_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

Compound EGFR mutation is frequently detected with co-mutations of actionable genes and associated with poor clinical outcome in lung adenocarcinoma.

Cancer Biology & Therapy

Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS

Publication Date: 2016

Variant appearance in text: KRAS: 169G>A

PubMed Link: 26785607

Variant Present in the following documents:

• kcbt-17-03-1139235.pdf

View BVdb publication page

---

Genetic heterogeneity of actionable genes between primary and metastatic tumor in lung adenocarcinoma.

Bmc Cancer

Kim, Eun Young EY; Cho, Eun Na EN; Park, Heae Surng HS; Kim, Arum A; Hong, Ji Young JY; Lim, Seri S; Youn, Jong Pil JP; Hwang, Seung Yong SY; Chang, Yoon Soo YS

Publication Date: 2016-01-18

Variant appearance in text: KRAS: 169G>A

PubMed Link: 26782967

Variant Present in the following documents:

• 12885_2016_2049_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

---

Protein domain-level landscape of cancer-type-specific somatic mutations.

Plos Computational Biology

Yang, Fan F; Petsalaki, Evangelia E; Rolland, Thomas T; Hill, David E DE; Vidal, Marc M; Roth, Frederick P FP

Publication Date: 2015-03

Variant appearance in text: KRAS: D57N

PubMed Link: 25794154

Variant Present in the following documents:

• pcbi.1004147.s001.xlsx, sheet 1

View BVdb publication page

---

Increased detection rates of EGFR and KRAS mutations in NSCLC specimens with low tumour cell content by 454 deep sequencing.

Virchows Archiv : An International Journal Of Pathology

Moskalev, Evgeny A EA; Stöhr, Robert R; Rieker, Ralf R; Hebele, Simone S; Fuchs, Florian F; Sirbu, Horia H; Mastitsky, Sergey E SE; Boltze, Carsten C; König, Helmut H; Agaimy, Abbas A; Hartmann, Arndt A; Haller, Florian F

Publication Date: 2013-04

Variant appearance in text: KRAS: 169G>A; D57N

PubMed Link: 23468066

Variant Present in the following documents:

• Main text
• 428_2013_Article_1376.pdf

View BVdb publication page

---