Publications:

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Characteristics and prognosis of rrDLBCL with TP53 mutations and a high-risk subgroup represented by the co-mutations of DDX3X-TP53.

Cancer Medicine

Gao, Fan F; Hu, Kai K; Zheng, Peihao P; Shi, Hui H; Ke, Xiaoyan X

Publication Date: 2023-03-27

Variant appearance in text: KRAS: 119A>G; Y40C

PubMed Link: 36971051

Variant Present in the following documents:

• CAM4-12-10267-s001.xlsx, sheet 1

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Genetic landscapes and curative effect of CAR T-cell immunotherapy in relapse and refractory DLBCL patients.

Blood Advances

Shi, Hui H; Zheng, Peihao P; Liu, Rui R; Xu, Teng T; Yang, Fan F; Feng, Shaomei S; Guo, Yuelu Y; Ma, Lixia L; Liu, Haidi H; Lei, Yang Y; Li, Ruiting R; Deng, Biping B; Hou, Shuling S; Li, Yang Y; Zheng, Qinlong Q; Hu, Kai K; Ke, Xiaoyan X

Publication Date: 2022-07-28

Variant appearance in text: KRAS: 119A>G; Y40C

PubMed Link: 35901280

Variant Present in the following documents:

• BLOODA_ADV-2021-006845-mmc1.xlsx, sheet 2

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Genetic Landscape of Relapsed and Refractory Diffuse Large B-Cell Lymphoma: A Systemic Review and Association Analysis With Next-Generation Sequencing.

Frontiers In Genetics

Gao, Fan F; Tian, Lei L; Shi, Hui H; Zheng, Peihao P; Wang, Jing J; Dong, Fei F; Hu, Kai K; Ke, Xiaoyan X

Publication Date: 2021

Variant appearance in text: KRAS: 119A>G; Y40C

PubMed Link: 34925435

Variant Present in the following documents:

• DataSheet2.xlsx, sheet 1

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Siah2 integrates mitogenic and extracellular matrix signals linking neuronal progenitor ciliogenesis with germinal zone occupancy.

Nature Communications

Ong, Taren T; Trivedi, Niraj N; Wakefield, Randall R; Frase, Sharon S; Solecki, David J DJ

Publication Date: 2020-10-20

Variant appearance in text: KRAS: Y40C

PubMed Link: 33082319

Variant Present in the following documents:

• 41467_2020_Article_19063.pdf

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Membrane interactions of the globular domain and the hypervariable region of KRAS4b define its unique diffusion behavior.

Elife

Goswami, Debanjan D; Chen, De ; Yang, Yue Y; Gudla, Prabhakar R PR; Columbus, John J; Worthy, Karen K; Rigby, Megan M; Wheeler, Madeline M; Mukhopadhyay, Suman S; Powell, Katie K; Burgan, William W; Wall, Vanessa V; Esposito, Dominic D; Simanshu, Dhirendra K DK; Lightstone, Felice C FC; Nissley, Dwight V DV; McCormick, Frank F; Turbyville, Thomas T

Publication Date: 2020-01-20

Variant appearance in text: KRAS: Y40C

PubMed Link: 31958057

Variant Present in the following documents:

• Main text
• elife-47654.pdf

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Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling.

Journal Of Molecular Biology

Muratcioglu, Serena S; Aydin, Cihan C; Odabasi, Ezgi E; Ozdemir, E Sila ES; Firat-Karalar, Elif Nur EN; Jang, Hyunbum H; Tsai, Chung-Jung CJ; Nussinov, Ruth R; Kavakli, Ibrahim Halil IH; Gursoy, Attila A; Keskin, Ozlem O

Publication Date: 2020-02-14

Variant appearance in text: K-Ras4B: Y40C

PubMed Link: 31931009

Variant Present in the following documents:

• Main text

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Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.

Cancer Discovery

Hobbs, G Aaron GA; Baker, Nicole M NM; Miermont, Anne M AM; Thurman, Ryan D RD; Pierobon, Mariaelena M; Tran, Timothy H TH; Anderson, Andrew O AO; Waters, Andrew M AM; Diehl, J Nathaniel JN; Papke, Bjoern B; Hodge, Richard G RG; Klomp, Jennifer E JE; Goodwin, Craig M CM; DeLiberty, Jonathan M JM; Wang, Junning J; Ng, Raymond W S RWS; Gautam, Prson P; Bryant, Kirsten L KL; Esposito, Dominic D; Campbell, Sharon L SL; Petricoin, Emanuel F EF; Simanshu, Dhirendra K DK; Aguirre, Andrew J AJ; Wolpin, Brian M BM; Wennerberg, Krister K; Rudloff, Udo U; Cox, Adrienne D AD; Der, Channing J CJ

Publication Date: 2020-01

Variant appearance in text: KRAS: Y40C

PubMed Link: 31649109

Variant Present in the following documents:

• Main text

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Failure to detect functional transfer of active K-Ras protein from extracellular vesicles into recipient cells in culture.

Plos One

Luhtala, Natalie N; Hunter, Tony T

Publication Date: 2018

Variant appearance in text: KRAS: Y40C

PubMed Link: 30192821

Variant Present in the following documents:

• pone.0203290.pdf

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: KRAS: Y40C

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 1
• pone.0196434.s001.xlsx, sheet 3
• pone.0196434.s001.xlsx, sheet 2

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Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules.

Cell

Grabocka, Elda E; Bar-Sagi, Dafna D

Publication Date: 2016-12-15

Variant appearance in text: KRAS: Y40C

PubMed Link: 27984728

Variant Present in the following documents:

• Main text

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Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover.

The Embo Journal

Hong, Xin X; Nguyen, Hung Thanh HT; Chen, Qingfeng Q; Zhang, Rui R; Hagman, Zandra Z; Voorhoeve, P Mathijs PM; Cohen, Stephen M SM

Publication Date: 2014-11-03

Variant appearance in text: KRAS: Y40C

PubMed Link: 25180228

Variant Present in the following documents:

• embj0033-2447-sd1.pdf

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Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma.

Bmc Genomics

Castle, John C JC; Loewer, Martin M; Boegel, Sebastian S; de Graaf, Jos J; Bender, Christian C; Tadmor, Arbel D AD; Boisguerin, Valesca V; Bukur, Thomas T; Sorn, Patrick P; Paret, Claudia C; Diken, Mustafa M; Kreiter, Sebastian S; Türeci, Özlem Ö; Sahin, Ugur U

Publication Date: 2014-03-13

Variant appearance in text: KRAS: Y40C

PubMed Link: 24621249

Variant Present in the following documents:

• Main text

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Ras effector mutant expression suggest a negative regulator inhibits lung tumor formation.

Plos One

Vandal, Guillaume G; Geiling, Benjamin B; Dankort, David D

Publication Date: 2014

Variant appearance in text: KRAS: Y40C

PubMed Link: 24489653

Variant Present in the following documents:

• Main text
• pone.0084745.pdf

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Ras history: The saga continues.

Small Gtpases

Cox, Adrienne D AD; Der, Channing J CJ

Publication Date: 2010-07

Variant appearance in text: K-Ras4B: Y40C

PubMed Link: 21686117

Variant Present in the following documents:

• Main text

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Death pathways triggered by activated Ras in cancer cells.

Frontiers In Bioscience (Landmark Edition)

Overmeyer, Jean H JH; Maltese, William A WA

Publication Date: 2011-01-01

Variant appearance in text: K-Ras4B: Y40C

PubMed Link: 21196257

Variant Present in the following documents:

• Main text

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Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.

The Embo Journal

Drosten, Matthias M; Dhawahir, Alma A; Sum, Eleanor Y M EY; Urosevic, Jelena J; Lechuga, Carmen G CG; Esteban, Luis M LM; Castellano, Esther E; Guerra, Carmen C; Santos, Eugenio E; Barbacid, Mariano M

Publication Date: 2010-03-17

Variant appearance in text: K-Ras4B: Y40C

PubMed Link: 20150892

Variant Present in the following documents:

• Main text

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Activated Ras induces cytoplasmic vacuolation and non-apoptotic death in glioblastoma cells via novel effector pathways.

Cellular Signalling

Kaul, Aparna A; Overmeyer, Jean H JH; Maltese, William A WA

Publication Date: 2007-05

Variant appearance in text: K-Ras4B: Y40C

PubMed Link: 17210246

Variant Present in the following documents:

• Main text

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Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase.

Molecular And Cellular Biology

McFall, A A; Ulkü, A A; Lambert, Q T QT; Kusa, A A; Rogers-Graham, K K; Der, C J CJ

Publication Date: 2001-08

Variant appearance in text: K-Ras4B: Y40C

PubMed Link: 11463831

Variant Present in the following documents:

• Main text

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