KRAS c.110A>G ;(p.E37G)

Variant ID: 12-25398209-T-C

NM_004985.3(KRAS):c.110A>G;(p.E37G)

This variant was identified in 14 publications

View GRCh38 version.




Publications:


Siah2 integrates mitogenic and extracellular matrix signals linking neuronal progenitor ciliogenesis with germinal zone occupancy.

Nature Communications
Ong, Taren T; Trivedi, Niraj N; Wakefield, Randall R; Frase, Sharon S; Solecki, David J DJ
Publication Date: 2020-10-20

Variant appearance in text: KRAS: E37G
PubMed Link: 33082319
Variant Present in the following documents:
  • 41467_2020_Article_19063.pdf
View BVdb publication page



Atypical KRASG12R Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer.

Cancer Discovery
Hobbs, G Aaron GA; Baker, Nicole M NM; Miermont, Anne M AM; Thurman, Ryan D RD; Pierobon, Mariaelena M; Tran, Timothy H TH; Anderson, Andrew O AO; Waters, Andrew M AM; Diehl, J Nathaniel JN; Papke, Bjoern B; Hodge, Richard G RG; Klomp, Jennifer E JE; Goodwin, Craig M CM; DeLiberty, Jonathan M JM; Wang, Junning J; Ng, Raymond W S RWS; Gautam, Prson P; Bryant, Kirsten L KL; Esposito, Dominic D; Campbell, Sharon L SL; Petricoin, Emanuel F EF; Simanshu, Dhirendra K DK; Aguirre, Andrew J AJ; Wolpin, Brian M BM; Wennerberg, Krister K; Rudloff, Udo U; Cox, Adrienne D AD; Der, Channing J CJ
Publication Date: 2020-01

Variant appearance in text: KRAS: E37G
PubMed Link: 31649109
Variant Present in the following documents:
  • Main text
View BVdb publication page



Active K-RAS induces the coherent rotation of epithelial cells: A model for collective cell invasion in vitro.

Cancer Science
Hirata, Eishu E; Ichikawa, Takehiko T; Horike, Shin-Ichi SI; Kiyokawa, Etsuko E
Publication Date: 2018-12

Variant appearance in text: KRAS: E37G
PubMed Link: 30281889
Variant Present in the following documents:
  • CAS-109-4045.pdf
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: E37G
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 3
  • pone.0196434.s001.xlsx, sheet 1
  • pone.0196434.s001.xlsx, sheet 2
View BVdb publication page



Molecular characterization of circulating colorectal tumor cells defines genetic signatures for individualized cancer care.

Oncotarget
Kong, Say Li SL; Liu, Xingliang X; Suhaimi, Nur-Afidah Mohamed NM; Koh, Kenneth Jia Hao KJH; Hu, Min M; Lee, Daniel Yoke San DYS; Cima, Igor I; Phyo, Wai Min WM; Lee, Esther Xing Wei EXW; Tai, Joyce A JA; Foong, Yu Miin YM; Vo, Jess Honganh JH; Koh, Poh Koon PK; Zhang, Tong T; Ying, Jackie Y JY; Lim, Bing B; Tan, Min-Han MH; Hillmer, Axel M AM
Publication Date: 2017-09-15

Variant appearance in text: KRAS: E37G
PubMed Link: 28978093
Variant Present in the following documents:
  • oncotarget-08-68026-s002.xlsx, sheet 3
View BVdb publication page



Mutant KRAS Enhances Tumor Cell Fitness by Upregulating Stress Granules.

Cell
Grabocka, Elda E; Bar-Sagi, Dafna D
Publication Date: 2016-12-15

Variant appearance in text: KRAS: E37G
PubMed Link: 27984728
Variant Present in the following documents:
  • Main text
View BVdb publication page



Opposing activities of the Ras and Hippo pathways converge on regulation of YAP protein turnover.

The Embo Journal
Hong, Xin X; Nguyen, Hung Thanh HT; Chen, Qingfeng Q; Zhang, Rui R; Hagman, Zandra Z; Voorhoeve, P Mathijs PM; Cohen, Stephen M SM
Publication Date: 2014-11-03

Variant appearance in text: KRAS: E37G
PubMed Link: 25180228
Variant Present in the following documents:
  • embj0033-2447-sd1.pdf
View BVdb publication page



Ras effector mutant expression suggest a negative regulator inhibits lung tumor formation.

Plos One
Vandal, Guillaume G; Geiling, Benjamin B; Dankort, David D
Publication Date: 2014

Variant appearance in text: KRAS: E37G
PubMed Link: 24489653
Variant Present in the following documents:
  • Main text
  • pone.0084745.pdf
View BVdb publication page



Defective K-Ras oncoproteins overcome impaired effector activation to initiate leukemia in vivo.

Blood
Shieh, Angell A; Ward, Ashley F AF; Donlan, Kegan L KL; Harding-Theobald, Emily R ER; Xu, Jin J; Mullighan, Charles G CG; Zhang, Chao C; Chen, Shann-Ching SC; Su, Xiaoping X; Downing, James R JR; Bollag, Gideon E GE; Shannon, Kevin M KM
Publication Date: 2013-06-13

Variant appearance in text: KRAS: E37G
PubMed Link: 23637129
Variant Present in the following documents:
  • Main text
View BVdb publication page



Ras history: The saga continues.

Small Gtpases
Cox, Adrienne D AD; Der, Channing J CJ
Publication Date: 2010-07

Variant appearance in text: K-Ras4B: E37G
PubMed Link: 21686117
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival.

The Embo Journal
Drosten, Matthias M; Dhawahir, Alma A; Sum, Eleanor Y M EY; Urosevic, Jelena J; Lechuga, Carmen G CG; Esteban, Luis M LM; Castellano, Esther E; Guerra, Carmen C; Santos, Eugenio E; Barbacid, Mariano M
Publication Date: 2010-03-17

Variant appearance in text: K-Ras4B: E37G
PubMed Link: 20150892
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Ras-association domain family (RASSF) members and their role in human tumourigenesis.

Biochimica Et Biophysica Acta
van der Weyden, Louise L; Adams, David J DJ
Publication Date: 2007-09

Variant appearance in text: KRAS: E37G
PubMed Link: 17692468
Variant Present in the following documents:
  • Main text
View BVdb publication page



Activated Ras induces cytoplasmic vacuolation and non-apoptotic death in glioblastoma cells via novel effector pathways.

Cellular Signalling
Kaul, Aparna A; Overmeyer, Jean H JH; Maltese, William A WA
Publication Date: 2007-05

Variant appearance in text: K-Ras4B: E37G
PubMed Link: 17210246
Variant Present in the following documents:
  • Main text
View BVdb publication page



Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase.

Molecular And Cellular Biology
McFall, A A; Ulkü, A A; Lambert, Q T QT; Kusa, A A; Rogers-Graham, K K; Der, C J CJ
Publication Date: 2001-08

Variant appearance in text: K-Ras4B: E37G
PubMed Link: 11463831
Variant Present in the following documents:
  • Main text
View BVdb publication page