KRAS c.109G>A ;(p.E37K)

Variant ID: 12-25398210-C-T

NM_004985.3(KRAS):c.109G>A;(p.E37K)

This variant was identified in 12 publications

View GRCh38 version.




Publications:


Correlation of changes in subclonal architecture with progression in the MMRF CoMMpass study.

Translational Oncology
Kaur, Gurvinder G; Jena, Lingaraja L; Gupta, Ritu R; Farswan, Akanksha A; Gupta, Anubha A; Sriram, K K
Publication Date: 2022-06-28

Variant appearance in text: KRAS: 109G>A; Glu37Lys
PubMed Link: 35777247
Variant Present in the following documents:
  • mmc5.xls, sheet 3
View BVdb publication page



A scalable high-throughput targeted next-generation sequencing assay for comprehensive genomic profiling of solid tumors.

Plos One
Conroy, Jeffrey M JM; Pabla, Sarabjot S; Glenn, Sean T ST; Seager, R J RJ; Van Roey, Erik E; Gao, Shuang S; Burgher, Blake B; Andreas, Jonathan J; Giamo, Vincent V; Mallon, Melissa M; Lee, Yong Hee YH; DePietro, Paul P; Nesline, Mary M; Wang, Yirong Y; Lenzo, Felicia L FL; Klein, Roger R; Zhang, Shengle S
Publication Date: 2021

Variant appearance in text: KRAS: 109G>A; E37K
PubMed Link: 34855780
Variant Present in the following documents:
  • pone.0260089.s001.xlsx, sheet 12
View BVdb publication page



A scalable high-throughput targeted next-generation sequencing assay for comprehensive genomic profiling of solid tumors.

Plos One
Conroy, Jeffrey M JM; Pabla, Sarabjot S; Glenn, Sean T ST; Seager, R J RJ; Van Roey, Erik E; Gao, Shuang S; Burgher, Blake B; Andreas, Jonathan J; Giamo, Vincent V; Mallon, Melissa M; Lee, Yong Hee YH; DePietro, Paul P; Nesline, Mary M; Wang, Yirong Y; Lenzo, Felicia L FL; Klein, Roger R; Zhang, Shengle S
Publication Date: 2021

Variant appearance in text: KRAS: 109G>A; E37K
PubMed Link: 34855780
Variant Present in the following documents:
  • pone.0260089.s001.xlsx, sheet 12
View BVdb publication page



Whole-exome sequencing in eccrine porocarcinoma indicates promising therapeutic strategies.

Cancer Gene Therapy
Denisova, Evgeniya E; Westphal, Dana D; Surowy, Harald M HM; Meier, Friedegund F; Hutter, Barbara B; Reifenberger, Julia J; Rütten, Arno A; Schulz, Alexander A; Sergon, Mildred M; Ziemer, Mirjana M; Brors, Benedikt B; Betz, Regina C RC; Redler, Silke S
Publication Date: 2022-06

Variant appearance in text: KRAS: E37K
PubMed Link: 34045664
Variant Present in the following documents:
  • 41417_2021_347_MOESM4_ESM.xls, sheet 7
View BVdb publication page



Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One
Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS
Publication Date: 2018

Variant appearance in text: KRAS: E37K
PubMed Link: 29698444
Variant Present in the following documents:
  • pone.0196434.s001.xlsx, sheet 2
  • pone.0196434.s001.xlsx, sheet 3
View BVdb publication page



Mutational landscape reflects the biological continuum of plasma cell dyscrasias.

Blood Cancer Journal
Rossi, A A; Voigtlaender, M M; Janjetovic, S S; Thiele, B B; Alawi, M M; März, M M; Brandt, A A; Hansen, T T; Radloff, J J; Schön, G G; Hegenbart, U U; Schönland, S S; Langer, C C; Bokemeyer, C C; Binder, M M
Publication Date: 2017-02-24

Variant appearance in text: KRAS: E37K
PubMed Link: 28234344
Variant Present in the following documents:
  • Main text
  • bcj201719a.pdf
View BVdb publication page



Drugging Ras GTPase: a comprehensive mechanistic and signaling structural view.

Chemical Society Reviews
Lu, Shaoyong S; Jang, Hyunbum H; Gu, Shuo S; Zhang, Jian J; Nussinov, Ruth R
Publication Date: 2016-09-21

Variant appearance in text: K-Ras4B: E37K
PubMed Link: 27396271
Variant Present in the following documents:
  • Main text
View BVdb publication page



Comparison of the Conformations of KRAS Isoforms, K-Ras4A and K-Ras4B, Points to Similarities and Significant Differences.

The Journal Of Physical Chemistry. B
Chakrabarti, Mayukh M; Jang, Hyunbum H; Nussinov, Ruth R
Publication Date: 2016-02-04

Variant appearance in text: K-Ras4B: E37K
PubMed Link: 26761128
Variant Present in the following documents:
  • Main text
View BVdb publication page



High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site.

Biophysical Journal
Chavan, Tanmay S TS; Jang, Hyunbum H; Khavrutskii, Lyuba L; Abraham, Sherwin J SJ; Banerjee, Avik A; Freed, Benjamin C BC; Johannessen, Liv L; Tarasov, Sergey G SG; Gaponenko, Vadim V; Nussinov, Ruth R; Tarasova, Nadya I NI
Publication Date: 2015-12-15

Variant appearance in text: K-Ras4B: E37K
PubMed Link: 26682817
Variant Present in the following documents:
  • Main text
View BVdb publication page



Next-generation sequencing of tyrosine kinase inhibitor-resistant non-small-cell lung cancers in patients harboring epidermal growth factor-activating mutations.

Bmc Cancer
Masago, Katsuhiro K; Fujita, Shiro S; Muraki, Miho M; Hata, Akito A; Okuda, Chiyuki C; Otsuka, Kyoko K; Kaji, Reiko R; Takeshita, Jumpei J; Kato, Ryoji R; Katakami, Nobuyuki N; Hirata, Yukio Y
Publication Date: 2015-11-16

Variant appearance in text: KRAS: E37K
PubMed Link: 26572169
Variant Present in the following documents:
  • Main text
  • 12885_2015_Article_1925.pdf
View BVdb publication page



GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site.

The Journal Of Biological Chemistry
Lu, Shaoyong S; Banerjee, Avik A; Jang, Hyunbum H; Zhang, Jian J; Gaponenko, Vadim V; Nussinov, Ruth R
Publication Date: 2015-11-27

Variant appearance in text: K-Ras4B: E37K
PubMed Link: 26453300
Variant Present in the following documents:
  • Main text
View BVdb publication page



Application of whole genome and RNA sequencing to investigate the genomic landscape of common variable immunodeficiency disorders.

Clinical Immunology (Orlando, Fla.)
van Schouwenburg, Pauline A PA; Davenport, Emma E EE; Kienzler, Anne-Kathrin AK; Marwah, Ishita I; Wright, Benjamin B; Lucas, Mary M; Malinauskas, Tomas T; Martin, Hilary C HC; , ; Lockstone, Helen E HE; Cazier, Jean-Baptiste JB; Chapel, Helen M HM; Knight, Julian C JC; Patel, Smita Y SY
Publication Date: 2015-10

Variant appearance in text: KRAS: 109G>A
PubMed Link: 26122175
Variant Present in the following documents:
  • emss-64345.pdf
View BVdb publication page



Applicability of next-generation sequencing to decalcified formalin-fixed and paraffin-embedded chronic myelomonocytic leukaemia samples.

International Journal Of Clinical And Experimental Pathology
Bernard, Veronica V; Gebauer, Niklas N; Dinh, Thomas T; Stegemann, Judith J; Feller, Alfred C AC; Merz, Hartmut H
Publication Date: 2014

Variant appearance in text: KRAS: E37K
PubMed Link: 24817963
Variant Present in the following documents:
  • Main text
View BVdb publication page