KRAS c.49A>T ;(p.S17C)

Variant ID: 12-25398270-T-A

NM_004985.3(KRAS):c.49A>T;(p.S17C)

This variant was identified in 13 publications

View GRCh38 version.




Publications:


Systematic analysis of the aberrances and functional implications of cuproptosis in cancer.

Iscience
Li, Jiangbing J; Li, Boyan B; Zhao, Rongrong R; Li, Gang G
Publication Date: 2023-04-21

Variant appearance in text: KRAS: S17C
PubMed Link: 36950125
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Loss of adipose TET proteins enhances β-adrenergic responses and protects against obesity by epigenetic regulation of β3-AR expression.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Byun, Seongjun S; Lee, Chan Hyeong CH; Jeong, Hyeongmin H; Kim, Hyejin H; Kwon, Hyug Moo HM; Park, Sungho S; Myung, Kyungjae K; An, Jungeun J; Ko, Myunggon M
Publication Date: 2022-06-28

Variant appearance in text: KRAS: S17C
PubMed Link: 35737830
Variant Present in the following documents:
  • pnas.2205626119.sapp.pdf
View BVdb publication page



Phasing analysis of lung cancer genomes using a long read sequencer.

Nature Communications
Sakamoto, Yoshitaka Y; Miyake, Shuhei S; Oka, Miho M; Kanai, Akinori A; Kawai, Yosuke Y; Nagasawa, Satoi S; Shiraishi, Yuichi Y; Tokunaga, Katsushi K; Kohno, Takashi T; Seki, Masahide M; Suzuki, Yutaka Y; Suzuki, Ayako A
Publication Date: 2022-06-16

Variant appearance in text: KRAS: S17c
PubMed Link: 35710642
Variant Present in the following documents:
  • 41467_2022_31133_MOESM1_ESM.pdf
View BVdb publication page



Efficacy and safety of first-line checkpoint inhibitors-based treatments for non-oncogene-addicted non-small-cell lung cancer: a systematic review and meta-analysis.

Esmo Open
Siciliano, M A MA; Caridà, G G; Ciliberto, D D; d'Apolito, M M; Pelaia, C C; Caracciolo, D D; Riillo, C C; Correale, P P; Galvano, A A; Russo, A A; Barbieri, V V; Tassone, P P; Tagliaferri, P P
Publication Date: 2022-06

Variant appearance in text: KRAS: S17C
PubMed Link: 35427835
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



High Grade of Amplification of Six Regions on Chromosome 2p in a Neuroblastoma Patient with Very Poor Outcome: The Putative New Oncogene TSSC1.

Cancers
Ognibene, Marzia M; Amoroso, Loredana L; Melchionda, Fraia F; Cangelosi, Davide D; Zara, Federico F; Parodi, Stefano S; Pezzolo, Annalisa A
Publication Date: 2021-11-18

Variant appearance in text: KRAS: S17C
PubMed Link: 34830942
Variant Present in the following documents:
  • Main text
  • cancers-13-05792.pdf
View BVdb publication page



The Q61H mutation decouples KRAS from upstream regulation and renders cancer cells resistant to SHP2 inhibitors.

Nature Communications
Gebregiworgis, Teklab T; Kano, Yoshihito Y; St-Germain, Jonathan J; Radulovich, Nikolina N; Udaskin, Molly L ML; Mentes, Ahmet A; Huang, Richard R; Poon, Betty P K BPK; He, Wenguang W; Valencia-Sama, Ivette I; Robinson, Claire M CM; Huestis, Melissa M; Miao, Jinmin J; Yeh, Jen Jen JJ; Zhang, Zhong-Yin ZY; Irwin, Meredith S MS; Lee, Jeffrey E JE; Tsao, Ming-Sound MS; Raught, Brian B; Marshall, Christopher B CB; Ohh, Michael M; Ikura, Mitsuhiko M
Publication Date: 2021-11-01

Variant appearance in text: KRAS: S17c
PubMed Link: 34725361
Variant Present in the following documents:
  • 41467_2021_26526_MOESM2_ESM.pdf
View BVdb publication page



An in vitro model of tumor heterogeneity resolves genetic, epigenetic, and stochastic sources of cell state variability.

Plos Biology
Hayford, Corey E CE; Tyson, Darren R DR; Robbins, C Jack CJ; Frick, Peter L PL; Quaranta, Vito V; Harris, Leonard A LA
Publication Date: 2021-06

Variant appearance in text: KRAS: S17C
PubMed Link: 34061819
Variant Present in the following documents:
  • pbio.3000797.s017.pdf
View BVdb publication page



Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor.

Molecular Systems Biology
Jaiswal, Alok A; Gautam, Prson P; Pietilä, Elina A EA; Timonen, Sanna S; Nordström, Nora N; Akimov, Yevhen Y; Sipari, Nina N; Tanoli, Ziaurrehman Z; Fleischer, Thomas T; Lehti, Kaisa K; Wennerberg, Krister K; Aittokallio, Tero T
Publication Date: 2021-03

Variant appearance in text: KRAS: S17C
PubMed Link: 33750001
Variant Present in the following documents:
  • Main text
  • MSB-17-e9526.pdf
View BVdb publication page



Spontaneous and frequent conformational dynamics induced by A…A mismatch in d(CAA)·d(TAG) duplex.

Scientific Reports
Ajjugal, Yogeeshwar Y; Tomar, Kripi K; Rao, D Krishna DK; Rathinavelan, Thenmalarchelvi T
Publication Date: 2021-02-11

Variant appearance in text: KRAS: S17C
PubMed Link: 33574412
Variant Present in the following documents:
  • 41598_2021_Article_82669.pdf
View BVdb publication page



Integrated analysis of whole genome and transcriptome sequencing in a young patient with gastric cancer provides insights for precision therapy.

Oncology Letters
Hu, Kongwang K; Yu, Weiqiang W; Ajayi, Olugbenga Emmanuel OE; Li, Longlong L; Huang, Zhiguo Z; Rong, Qiqi Q; Wang, Shuaili S; Wu, Qing-Fa QF
Publication Date: 2020-10

Variant appearance in text: KRAS: S17C
PubMed Link: 32863928
Variant Present in the following documents:
  • Main text
  • ol-20-04-11976.pdf
View BVdb publication page



Stromal Modulation and Treatment of Metastatic Pancreatic Cancer with Local Intraperitoneal Triple miRNA/siRNA Nanotherapy.

Acs Nano
Xie, Ying Y; Hang, Yu Y; Wang, Yazhe Y; Sleightholm, Richard R; Prajapati, Dipakkumar R DR; Bader, Johannes J; Yu, Ao A; Tang, Weimin W; Jaramillo, Lee L; Li, Jing J; Singh, Rakesh K RK; Oupický, David D
Publication Date: 2020-01-28

Variant appearance in text: KRAS: S17C
PubMed Link: 31927946
Variant Present in the following documents:
  • Main text
View BVdb publication page



NMR solution structure of an asymmetric intermolecular leaped V-shape G-quadruplex: selective recognition of the d(G2NG3NG4) sequence motif by a short linear G-rich DNA probe.

Nucleic Acids Research
Wan, Chanjuan C; Fu, Wenqiang W; Jing, Haitao H; Zhang, Na N
Publication Date: 2019-02-20

Variant appearance in text: KRAS: S17C
PubMed Link: 30445650
Variant Present in the following documents:
  • gky1167.pdf
View BVdb publication page



Failure to induce apoptosis via BCL-2 family proteins underlies lack of efficacy of combined MEK and PI3K inhibitors for KRAS-mutant lung cancers.

Cancer Research
Hata, Aaron N AN; Yeo, Alan A; Faber, Anthony C AC; Lifshits, Eugene E; Chen, Zhao Z; Cheng, Katherine A KA; Walton, Zandra Z; Sarosiek, Kristopher A KA; Letai, Anthony A; Heist, Rebecca S RS; Mino-Kenudson, Mari M; Wong, Kwok-Kin KK; Engelman, Jeffrey A JA
Publication Date: 2014-06-01

Variant appearance in text: KRAS: S17C
PubMed Link: 24675361
Variant Present in the following documents:
  • Main text
View BVdb publication page