Publications:

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In PD-1+ human colon cancer cells NIVOLUMAB promotes survival and could protect tumor cells from conventional therapies.

Journal For Immunotherapy Of Cancer

Ieranò, Caterina C; Righelli, Dario D; D'Alterio, Crescenzo C; Napolitano, Maria M; Portella, Luigi L; Rea, Giuseppina G; Auletta, Federica F; Santagata, Sara S; Trotta, Anna Maria AM; Guardascione, Giuseppe G; Liotti, Federica F; Prevete, Nella N; Maiolino, Piera P; Luciano, Antonio A; Barbieri, Antonio A; Di Mauro, Annabella A; Roma, Cristin C; Esposito Abate, Riziero R; Tatangelo, Fabiana F; Pacelli, Roberto R; Normanno, Nicola N; Melillo, Rosa Marina RM; Scala, Stefania S

Publication Date: 2022-03

Variant appearance in text: KRAS: V14A

PubMed Link: 35246475

Variant Present in the following documents:

• jitc-2021-004032supp001.pdf

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Discovery of cell active macrocyclic peptides with on-target inhibition of KRAS signaling.

Chemical Science

Lim, Shuhui S; Boyer, Nicolas N; Boo, Nicole N; Huang, Chunhui C; Venkatachalam, Gireedhar G; Angela Juang, Yu-Chi YC; Garrigou, Michael M; Kaan, Hung Yi Kristal HYK; Duggal, Ruchia R; Peh, Khong Ming KM; Sadruddin, Ahmad A; Gopal, Pooja P; Yuen, Tsz Ying TY; Ng, Simon S; Kannan, Srinivasaraghavan S; Brown, Christopher J CJ; Verma, Chandra S CS; Orth, Peter P; Peier, Andrea A; Ge, Lan L; Yu, Xiang X; Bhatt, Bhavana B; Chen, Feifei F; Wang, Erjia E; Li, Nianyu Jason NJ; Gonzales, Raymond J RJ; Stoeck, Alexander A; Henry, Brian B; Sawyer, Tomi K TK; Lane, David P DP; Johannes, Charles W CW; Biswas, Kaustav K; Partridge, Anthony W AW

Publication Date: 2021-12-15

Variant appearance in text: KRAS: Val14Ala

PubMed Link: 35024121

Variant Present in the following documents:

• Main text
• SC-012-D1SC05187C.pdf
• SC-012-D1SC05187C-s001.pdf

View BVdb publication page

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Infrequent RAS mutation is not associated with specific histological phenotype in gliomas.

Bmc Cancer

Makino, Yasuhide Y; Arakawa, Yoshiki Y; Yoshioka, Ema E; Shofuda, Tomoko T; Minamiguchi, Sachiko S; Kawauchi, Takeshi T; Tanji, Masahiro M; Kanematsu, Daisuke D; Nonaka, Masahiro M; Okita, Yoshiko Y; Kodama, Yoshinori Y; Mano, Masayuki M; Hirose, Takanori T; Mineharu, Yohei Y; Miyamoto, Susumu S; Kanemura, Yonehiro Y

Publication Date: 2021-09-15

Variant appearance in text: KRAS: V14A

PubMed Link: 34525976

Variant Present in the following documents:

• Main text
• 12885_2021_Article_8733.pdf

View BVdb publication page

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Recent Updates on the Significance of KRAS Mutations in Colorectal Cancer Biology.

Cells

László, Loretta L; Kurilla, Anita A; Takács, Tamás T; Kudlik, Gyöngyi G; Koprivanacz, Kitti K; Buday, László L; Vas, Virag V

Publication Date: 2021-03-17

Variant appearance in text: KRAS: V14A

PubMed Link: 33802849

Variant Present in the following documents:

• Main text
• cells-10-00667.pdf

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Identification of relevant genetic alterations in cancer using topological data analysis.

Nature Communications

Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG

Publication Date: 2020-07-30

Variant appearance in text: KRAS: V14A

PubMed Link: 32732999

Variant Present in the following documents:

• 41467_2020_17659_MOESM3_ESM.xls, sheet 1

View BVdb publication page

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: KRAS: V14A

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 1
• pone.0196434.s001.xlsx, sheet 2

View BVdb publication page

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Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies.

Molecular Cancer

Berg, Kaja C G KCG; Eide, Peter W PW; Eilertsen, Ina A IA; Johannessen, Bjarne B; Bruun, Jarle J; Danielsen, Stine A SA; Bjørnslett, Merete M; Meza-Zepeda, Leonardo A LA; Eknæs, Mette M; Lind, Guro E GE; Myklebost, Ola O; Skotheim, Rolf I RI; Sveen, Anita A; Lothe, Ragnhild A RA

Publication Date: 2017-07-06

Variant appearance in text: KRAS: V14A

PubMed Link: 28683746

Variant Present in the following documents:

• Main text
• 12943_2017_691_MOESM1_ESM.xlsx, sheet 5
• 12943_2017_Article_691.pdf

View BVdb publication page

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KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese patients with colorectal cancer.

Plos One

Mao, Chen C; Zhou, Junhua J; Yang, Zuyao Z; Huang, Yafang Y; Wu, Xinyin X; Shen, Hong H; Tang, Jinling J; Chen, Qing Q

Publication Date: 2012

Variant appearance in text: KRAS: V14A

PubMed Link: 22586484

Variant Present in the following documents:

• Main text
• pone.0036653.pdf

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