Variant ID: 12-25398281-C-T

NM_033360.2(KRAS):c.38G>A;(p.Gly13Asp)

This variant was identified in 1433 publications




Publications:


Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine
J Li, W Jiang, J Wei, J Zhang, L Cai, M Luo, Z Wang, W Sun, S Wang, C Wang, C Dai, J Liu, G Wang, J Wang, Q Xu, Y Deng
Publication Date: 2020-08-01

Variant appearance in text: KRAS: G13D
PMID: 32738923
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Protein Arginine Methyltransferase 5 as a Therapeutic Target for KRAS Mutated Colorectal Cancer.

Cancers
D Shifteh, T Sapir, M Pahmer, A Haimowitz, S Goel, R Maitra
Publication Date: 2020-07-28

Variant appearance in text: KRAS: G13D
PMID: 32731506
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Mcl-1 inhibition overcomes intrinsic and acquired regorafenib resistance in colorectal cancer.

Theranostics
X Song, L Shen, J Tong, C Kuang, S Zeng, RE Schoen, J Yu, H Pei, L Zhang
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32724460
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Multitarget stool DNA test compared with fecal occult blood test for colorectal cancer screening.

Oncology Letters
C Yang, W Wu, Y Yang, X Yang, J Sun, W Zhang, K Liu, H Ying, S Jiang, X Yu, Y Shi, Y Zhou, S Zhu, Y Xu, Y Ding, L Xie, B Cai, X Xin, P Chen, R Zhao, Y Wu
Publication Date: 2020-08

Variant appearance in text: KRAS: Gly13Asp
PMID: 32724359
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Study of Ras Mutations' Prognostic Value in Metastatic Colorectal Cancer: STORIA Analysis.

Cancers
A Ottaiano, N Normanno, S Facchini, A Cassata, A Nappi, C Romano, L Silvestro, A De Stefano, AM Rachiglio, C Roma, MR Maiello, S Scala, P Delrio, F Tatangelo, A Di Mauro, G Botti, A Avallone, G Nasti
Publication Date: 2020-07-16

Variant appearance in text: KRAS: G13D
PMID: 32708575
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Leukaemia Inhibitory Factor (LIF) Inhibits Cancer Stem Cells Tumorigenic Properties through Hippo Kinases Activation in Gastric Cancer.

Cancers
L Seeneevassen, J Giraud, S Molina-Castro, E Sifré, C Tiffon, C Beauvoit, C Staedel, F Mégraud, P Lehours, OCB Martin, H Boeuf, P Dubus, C Varon
Publication Date: 2020-07-22

Variant appearance in text: KRAS: 38G>A; Gly13Asp
PMID: 32707998
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Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR.

Scientific Reports
Y Ono, A Hayashi, C Maeda, M Suzuki, R Wada, H Sato, H Kawabata, T Okada, T Goto, H Karasaki, Y Mizukami, T Okumura
Publication Date: 2020-07-23

Variant appearance in text: KRAS: G13D
PMID: 32704002
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AMPK activation overcomes anti-EGFR antibody resistance induced by KRAS mutation in colorectal cancer.

Cell Communication And Signaling : Ccs
H Ye, Y Liu, K Wu, H Luo, L Cui
Publication Date: 2020-07-23

Variant appearance in text: KRAS: G13D
PMID: 32703218
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Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR.

Cell Reports
W Yan, E Markegard, S Dharmaiah, A Urisman, M Drew, D Esposito, K Scheffzek, DV Nissley, F McCormick, DK Simanshu
Publication Date: 2020-07-21

Variant appearance in text: KRAS: G13D
PMID: 32697994
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KRAS-associated microRNAs in colorectal cancer.

Oncology Reviews
H Ibrahim, YC Lim
Publication Date: 2020-07-06

Variant appearance in text: KRAS: G13D
PMID: 32685110
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miRNAs-Based Molecular Signature for KRAS Mutated and Wild Type Colorectal Cancer: An Explorative Study.

Journal Of Immunology Research
E Milanesi, M Dobre, AI Bucuroiu, V Herlea, TE Manuc, A Salvi, G De Petro, M Manuc, G Becheanu
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32676506
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BRAF and KRAS mutations in metastatic colorectal cancer: future perspectives for personalized therapy.

Gastroenterology Report
ZN Li, L Zhao, LF Yu, MJ Wei
Publication Date: 2020-06

Variant appearance in text: KRAS: G13D
PMID: 32665851
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A Pilot Study for the Feasibility of Exome-Sequencing in Circulating Tumor Cells Versus Single Metastatic Biopsies in Breast Cancer.

International Journal Of Molecular Sciences
P Kaur, D Campo, TB Porras, A Ring, J Lu, Y Chairez, Y Su, I Kang, JE Lang
Publication Date: 2020-07-08

Variant appearance in text: KRAS: G13D
PMID: 32650480
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Genomic characterization of Chinese ovarian clear cell carcinoma identifies driver genes by whole exome sequencing.

Neoplasia (New York, N.Y.)
Q Yang, C Zhang, Y Ren, H Yi, T Luo, F Xing, X Bai, L Cui, L Zhu, J Ouyang, P Jiang, W Fan, J Qiu, F Wang, X Xing, Z Zhang, X Zhang, R Zhang
Publication Date: 2020-07-07

Variant appearance in text: KRAS: G13D
PMID: 32650224
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Evaluation of molecular subtypes and clonal selection during establishment of patient-derived tumor xenografts from gastric adenocarcinoma.

Communications Biology
AL Peille, V Vuaroqueaux, SS Wong, J Ting, K Klinger, B Zeitouni, M Landesfeind, WH Kim, HJ Lee, SH Kong, I Wulur, S Bray, P Bronsert, N Zanella, G Donoho, HK Yang, HH Fiebig, C Reinhard, A Aggarwal
Publication Date: 2020-07-09

Variant appearance in text: KRAS: G13D
PMID: 32647357
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Impact of concurrent genomic alterations in epidermal growth factor receptor (EGFR)-mutated lung cancer.

Journal Of Thoracic Disease
B Gini, N Thomas, CM Blakely
Publication Date: 2020-05

Variant appearance in text: KRAS: G13D
PMID: 32642201
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KRAS Mutation-Responsive miR-139-5p inhibits Colorectal Cancer Progression and is repressed by Wnt Signaling.

Theranostics
F Du, T Cao, H Xie, T Li, L Sun, H Liu, H Guo, X Wang, Q Liu, T Kim, JL Franklin, R Graves-Deal, W Han, Z Tian, M Ge, Y Nie, D Fan, RJ Coffey, Y Lu, X Zhao
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32641995
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The role of mucin cell-free DNA detection as a new marker for the study of acellular pseudomyxoma peritonei of appendicular origin by liquid biopsy.

Therapeutic Advances In Medical Oncology
D García-Olmo, S Olmedillas-López, D Cortés-Guiral, P Villarejo, I López Rojo, H Guadalajara, S García Gómez-Heras, M García-Arranz
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32636940
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MEK activation drives glycolysis and supports suppressive myeloid cells in TNBC.

Jci Insight
DA Franklin, JT Sharick, PI Gonzalez-Ericsson, V Sanchez, P Dean, SR Opalenik, S Cairo, JG Judde, MT Lewis, JC Chang, ME Sanders, RS Cook, MC Skala, J Bordeaux, JO Bender, CA Vaupel, G Geiss, D Hinerfeld, JM Balko
Publication Date: 2020-07-07

Variant appearance in text: KRAS: G13D
PMID: 32634121
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Germline and Somatic Pharmacogenomics to Refine Rectal Cancer Patients Selection for Neo-Adjuvant Chemoradiotherapy.

Frontiers In Pharmacology
E De Mattia, R Roncato, E Palazzari, G Toffoli, E Cecchin
Publication Date: 2020

Variant appearance in text: KRAS: Gly13Asp
PMID: 32625092
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Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe.

Cell Death & Disease
B Gastl, K Klotz-Noack, B Klinger, S Ispasanie, KHF Salib, J Zuber, S Mamlouk, N Bublitz, N Blüthgen, D Horst, M Morkel, R Schäfer, C Sers
Publication Date: 2020-07-01

Variant appearance in text: KRAS: G13D
PMID: 32612138
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Targeting Altered Energy Metabolism in Colorectal Cancer: Oncogenic Reprogramming, the Central Role of the TCA Cycle and Therapeutic Opportunities.

Cancers
C Neitzel, P Demuth, S Wittmann, J Fahrer
Publication Date: 2020-06-29

Variant appearance in text: KRAS: G13D
PMID: 32610612
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Inhibition of lncRNA PART1 Chemosensitizes Wild Type but Not KRAS Mutant NSCLC Cells.

Cancer Management And Research
SC Chen, YZ Diao, ZH Zhao, XL Li
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32606939
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Promoter Methylation of Selected Genes in Non-Small-Cell Lung Cancer Patients and Cell Lines.

International Journal Of Molecular Sciences
V Sarne, S Huter, S Braunmueller, L Rakob, N Jacobi, M Kitzwögerer, C Wiesner, P Obrist, R Seeboeck
Publication Date: 2020-06-28

Variant appearance in text: KRAS: G13D
PMID: 32605217
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A potent KRAS macromolecule degrader specifically targeting tumours with mutant KRAS.

Nature Communications
N Bery, A Miller, T Rabbitts
Publication Date: 2020-06-26

Variant appearance in text: KRAS: G13D
PMID: 32591521
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Clinicopathological Characteristics and Mutation Spectrum of Colorectal Adenocarcinoma With Mucinous Component in a Chinese Cohort: Comparison With Classical Adenocarcinoma.

Frontiers In Oncology
J Chen, L Zhou, J Gao, T Lu, J Wang, H Wu, Z Liang
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32582557
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Active Compound of Pharbitis Semen (Pharbitis nil Seeds) Suppressed KRAS-Driven Colorectal Cancer and Restored Muscle Cell Function during Cancer Progression.

Molecules (Basel, Switzerland)
J Song, H Seo, MR Kim, SJ Lee, S Ahn, M Song
Publication Date: 2020-06-22

Variant appearance in text: KRAS: G13D
PMID: 32580297
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Optimization of a WGA-Free Molecular Tagging-Based NGS Protocol for CTCs Mutational Profiling.

International Journal Of Molecular Sciences
G De Luca, B Cardinali, L Del Mastro, S Lastraioli, F Carli, M Ferrarini, GA Calin, A Garuti, C Mazzitelli, S Zupo, M Dono
Publication Date: 2020-06-19

Variant appearance in text: KRAS: 38G>A; Gly13Asp
PMID: 32575430
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FAM83G Is a Novel Inducer of Apoptosis.

Molecules (Basel, Switzerland)
J Okada, N Sunaga, E Yamada, T Saito, A Ozawa, Y Nakajima, K Okada, JE Pessin, S Okada, M Yamada
Publication Date: 2020-06-18

Variant appearance in text: KRAS: G13D
PMID: 32570757
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Histology and its prognostic effect on KRAS-mutated colorectal carcinomas in Korea.

Oncology Letters
HS Lee, DY Hwang, HS Han
Publication Date: 2020-07

Variant appearance in text: KRAS: G13D
PMID: 32565990
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Mucinous borderline ovarian tumors with BRAFV600E mutation may have low risk for progression to invasive carcinomas.

Archives Of Gynecology And Obstetrics
K Ohnishi, K Nakayama, M Ishikawa, T Ishibashi, H Yamashita, K Nakamura, T Minamoto, K Iida, S Razia, N Ishikawa, S Kyo
Publication Date: 2020-06-16

Variant appearance in text: KRAS: G13D
PMID: 32556513
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Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers.

Cell Reports
I Ozkan-Dagliyan, JN Diehl, SD George, A Schaefer, B Papke, K Klotz-Noack, AM Waters, CM Goodwin, P Gautam, M Pierobon, S Peng, TSK Gilbert, KH Lin, O Dagliyan, K Wennerberg, EF Petricoin, NL Tran, SV Bhagwat, RV Tiu, SB Peng, LE Herring, LM Graves, C Sers, KC Wood, AD Cox, CJ Der
Publication Date: 2020-06-16

Variant appearance in text: KRAS: G13D
PMID: 32553168
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Application of targeted next generation sequencing for the mutational profiling of patients with acute lymphoblastic leukemia.

Journal Of Medical Biochemistry
D Janic, J Peric, T Karan-Djurasevic, T Kostic, I Marjanovic, B Stanic, N Pejanovic, L Dokmanovic, J Lazic, N Krstovski, M Virijevic, D Tomin, A Vidovic, N Suvajdzic-Vukovic, S Pavlovic, N Tosic
Publication Date: 2020-01-10

Variant appearance in text: KRAS: 38G>A; G13D; rs112445441
PMID: 32550823
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Identification of Altered Genes in Gallbladder Cancer as Potential Driver Mutations for Diagnostic and Prognostic Purposes: A Computational Approach.

Cancer Informatics
V D'Afonseca, AD Arencibia, A Echeverría-Vega, L Cerpa, JP Cayún, NM Varela, M Salazar, LA Quiñones
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32546937
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BRAF Mutated Colorectal Cancer: New Treatment Approaches.

Cancers
J Molina-Cerrillo, M San Román, J Pozas, T Alonso-Gordoa, M Pozas, E Conde, M Rosas, E Grande, ML García-Bermejo, A Carrato
Publication Date: 2020-06-14

Variant appearance in text: KRAS: G13D
PMID: 32545884
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Traditional serrated adenoma has two distinct genetic pathways for molecular tumorigenesis with potential neoplastic progression.

Journal Of Gastroenterology
Y Tanaka, M Eizuka, N Uesugi, K Kawasaki, H Yamano, H Suzuki, T Matsumoto, T Sugai
Publication Date: 2020-06-13

Variant appearance in text: KRAS: G13D
PMID: 32535664
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MICA Allele Facilitates the Metastasis of KRAS-Mutant Colorectal Cancer.

Frontiers In Genetics
W Ding, Y Ma, W Zhu, W Pu, J Zhang, F Qian, Y Zhou, Y Deng, S Guo, J Wang, X Zhou
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32528529
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A novel sensitive detection method for DNA methylation in circulating free DNA of pancreatic cancer.

Plos One
K Shinjo, K Hara, G Nagae, T Umeda, K Katsushima, M Suzuki, Y Murofushi, Y Umezu, I Takeuchi, S Takahashi, Y Okuno, K Matsuo, H Ito, S Tajima, H Aburatani, K Yamao, Y Kondo
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32520974
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Detection of Colorectal Cancer and Advanced Adenoma by Liquid Biopsy (Decalib Study): The ddPCR Challenge.

Cancers
A Junca, G Tachon, C Evrard, C Villalva, E Frouin, L Karayan-Tapon, D Tougeron
Publication Date: 2020-06-06

Variant appearance in text: KRAS: G13D
PMID: 32517177
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Drug-Drug Interactions of Irinotecan, 5-Fluorouracil, Folinic Acid and Oxaliplatin and Its Activity in Colorectal Carcinoma Treatment.

Molecules (Basel, Switzerland)
M Zoetemelk, GM Ramzy, M Rausch, P Nowak-Sliwinska
Publication Date: 2020-06-04

Variant appearance in text: KRAS: G13D
PMID: 32512790
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An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development.

Nature Communications
S Shankar, JC Tien, RF Siebenaler, S Chugh, VL Dommeti, S Zelenka-Wang, XM Wang, IJ Apel, J Waninger, S Eyunni, A Xu, M Mody, A Goodrum, Y Zhang, JJ Tesmer, R Mannan, X Cao, P Vats, S Pitchiaya, SJ Ellison, J Shi, C Kumar-Sinha, HC Crawford, AM Chinnaiyan
Publication Date: 2020-06-04

Variant appearance in text: KRAS: G13D
PMID: 32499547
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A H-REV107 Peptide Inhibits Tumor Growth and Interacts Directly with Oncogenic KRAS Mutants.

Cancers
CW Han, MS Jeong, SC Ha, SB Jang
Publication Date: 2020-05-30

Variant appearance in text: KRAS: G13D
PMID: 32486141
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Targeting TRAF3IP2, Compared to Rab27, is More Effective in Suppressing the Development and Metastasis of Breast Cancer.

Scientific Reports
EU Alt, PM Wörner, A Pfnür, JE Ochoa, DJ Schächtele, Z Barabadi, LM Lang, S Srivastav, ME Burow, B Chandrasekar, R Izadpanah
Publication Date: 2020-06-01

Variant appearance in text: KRAS: G13D
PMID: 32483202
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Role of Clostridium perfringens Enterotoxin on YAP Activation in Colonic Sessile Serrated Adenoma/ Polyps with Dysplasia.

International Journal Of Molecular Sciences
R Fujiwara-Tani, K Fujii, S Mori, S Kishi, T Sasaki, H Ohmori, C Nakashima, I Kawahara, Y Nishiguchi, T Mori, M Sho, M Kondoh, Y Luo, H Kuniyasu
Publication Date: 2020-05-28

Variant appearance in text: KRAS: G13D
PMID: 32481659
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Loss of tyrosine phosphatase SHP2 activity promotes growth of colorectal carcinoma HCT-116 cells.

Signal Transduction And Targeted Therapy
X Chen, X Fu, W Zhao, WT Ho, S Xing, ZJ Zhao
Publication Date: 2020-05-29

Variant appearance in text: KRAS: G13D
PMID: 32467571
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A novel NGS-based microsatellite instability (MSI) status classifier with 9 loci for colorectal cancer patients.

Journal Of Translational Medicine
K Zheng, H Wan, J Zhang, G Shan, N Chai, D Li, N Fang, L Liu, J Zhang, R Du, Q Wu, X Li, C Zhang
Publication Date: 2020-05-28

Variant appearance in text: KRAS: G13D
PMID: 32466784
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Application of Next-Generation Sequencing for the Genomic Characterization of Patients with Smoldering Myeloma.

Cancers
M Manzoni, V Marchica, P Storti, B Ziccheddu, G Sammarelli, G Todaro, F Pelizzoni, S Salerio, L Notarfranchi, A Pompa, L Baldini, N Bolli, A Neri, N Giuliani, M Lionetti
Publication Date: 2020-05-23

Variant appearance in text: KRAS: G13D
PMID: 32456143
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Metformin selectively inhibits metastatic colorectal cancer with the KRAS mutation by intracellular accumulation through silencing MATE1.

Proceedings Of The National Academy Of Sciences Of The United States Of America
J Xie, L Xia, W Xiang, W He, H Yin, F Wang, T Gao, W Qi, Z Yang, X Yang, T Zhou, G Gao
Publication Date: 2020-05-22

Variant appearance in text: KRAS: G13D
PMID: 32444490
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Tissue gene mutation profiles in patients with colorectal cancer and their clinical implications.

Biomedical Reports
J Ye, M Lin, C Zhang, X Zhu, S Li, H Liu, J Yin, H Yu, K Zhu
Publication Date: 2020-07

Variant appearance in text: KRAS: G13D
PMID: 32440349
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Tumor Location Is Associated With the Prevalence of Braf And Pik3ca Mutations in Patients with Wild-Type Ras Colorectal Cancer: A Prospective Multi-Center Cohort Study in Japan.

Translational Oncology
H Taniguchi, K Uehara, G Nakayama, H Nakayama, T Aiba, N Hattori, M Kataoka, Y Nakano, Y Kawase, O Okochi, H Matsuoka, S Utsunomiya, E Sakamoto, Y Mori, S Umeda, T Shikano, K Komori, M Tajika, S Kadowaki, K Muro, Y Yatabe
Publication Date: 2020-05-16

Variant appearance in text: KRAS: G13D
PMID: 32428838
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NADPH oxidase 1 is highly expressed in human large and small bowel cancers.

Plos One
J Lu, G Jiang, Y Wu, S Antony, JL Meitzler, A Juhasz, H Liu, K Roy, H Makhlouf, R Chuaqui, D Butcher, MM Konaté, JH Doroshow
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32428030
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Proteomic Characterization of Colorectal Cancer Cells versus Normal-Derived Colon Mucosa Cells: Approaching Identification of Novel Diagnostic Protein Biomarkers in Colorectal Cancer.

International Journal Of Molecular Sciences
M Ludvigsen, L Thorlacius-Ussing, H Vorum, MP Moyer, MT Stender, O Thorlacius-Ussing, B Honoré
Publication Date: 2020-05-14

Variant appearance in text: KRAS: G13D
PMID: 32422974
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Detection of Fusion Genes Using a Targeted RNA Sequencing Panel in Gastrointestinal and Rare Cancers.

Journal Of Oncology
SJ Lee, JY Hong, K Kim, KM Kim, SY Kang, T Lee, ST Kim, SH Park, YS Park, HY Lim, WK Kang, J Lee, JO Park
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32411236
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Dynamic alterations of genome and transcriptome in KRAS G13D mutant CRC PDX model treated with cetuximab.

Bmc Cancer
H Zhang, L Yuan, L Liu, C Yan, J Cheng, Q Fu, Z Tong, W Jiang, Y Zheng, P Zhao, G Zhang, W Fang
Publication Date: 2020-05-13

Variant appearance in text: KRAS: G13D
PMID: 32404198
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Liquid biopsy-based tumor profiling for metastatic colorectal cancer patients with ultra-deep targeted sequencing.

Plos One
JK Kang, S Heo, HP Kim, SH Song, H Yun, SW Han, GH Kang, D Bang, TY Kim
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32379795
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Comparative effects of oncogenic mutations G12C, G12V, G13D, and Q61H on local conformations and dynamics of K-Ras.

Computational And Structural Biotechnology Journal
S Vatansever, B Erman, ZH Gümüş
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32373288
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Mutation-Associated Phenotypic Heterogeneity in Novel and Canonical PIK3CA Helical and Kinase Domain Mutants.

Cells
AA Ghodsinia, JMT Lego, RL Garcia
Publication Date: 2020-04-30

Variant appearance in text: KRAS: G13D
PMID: 32365913
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Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non-small cell lung cancer: Analysis of over 8000 cases.

Cancer
PC Mack, KC Banks, CR Espenschied, RA Burich, OA Zill, CE Lee, JW Riess, SA Mortimer, A Talasaz, RB Lanman, DR Gandara
Publication Date: 2020-05-04

Variant appearance in text: KRAS: G13D
PMID: 32365229
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RAS Mutational Status Detection in Tissue, Plasma, and Stool Samples for Colorectal Cancer.

Biomed Research International
L Zhu, Y Wang, Y Zhou, Q Dong, Y Liu, J Zhang
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32351996
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Application of a Biphasic Mathematical Model of Cancer Cell Drug Response for Formulating Potent and Synergistic Targeted Drug Combinations to Triple Negative Breast Cancer Cells.

Cancers
J Shen, L Li, NG Howlett, PS Cohen, G Sun
Publication Date: 2020-04-27

Variant appearance in text: KRAS: G13D
PMID: 32349331
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A sporadic gastric-type endocervical adenocarcinoma with endometrial involvement and bilateral ovarian metastasis, a case report.

Gynecologic Oncology Reports
O Saglam, DI Lin, CB Steele, JK Killian, RM Wenham
Publication Date: 2020-05

Variant appearance in text: KRAS: G13D
PMID: 32346591
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The Clinical Relevance of Frequent Germline Genetic Variants Detected by Targeted Sequencing in Patients With Rectal Adenocarcinoma (READ).

Cancer Genomics & Proteomics
KC Huang, SF Chiang, TW Ke, WT Chen, TW Chen, KC Chao
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32345670
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Molecular Diagnostic of Solid Tumor Using a Next Generation Sequencing Custom-Designed Multi-Gene Panel.

Diagnostics (Basel, Switzerland)
D de Biase, G Acquaviva, M Visani, V Sanza, CM Argento, A De Leo, T Maloberti, A Pession, G Tallini
Publication Date: 2020-04-23

Variant appearance in text: KRAS: 38G>A; G13D
PMID: 32340363
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Improvement of digital PCR conditions for direct detection of KRAS mutations.

Journal Of Clinical Laboratory Analysis
J Lee, JH Kim, SH Kang, HM Yoo
Publication Date: 2020-04-24

Variant appearance in text: KRAS: 38G>A; G13D
PMID: 32329932
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Single-Center Experience With Epigenetic Treatment for Juvenile Myelomonocytic Leukemia.

Frontiers In Oncology
A Marcu, A Colita, LE Radu, CG Jercan, AM Bica, M Asan, D Coriu, AD Tanase, CC Diaconu, C Mambet, A Botezatu, S Pasca, P Teodorescu, G Anton, P Gurban, A Colita
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32328464
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Integrated data analysis reveals significant associations of KEAP1 mutations with DNA methylation alterations in lung adenocarcinomas.

Aging
M Elshaer, AI ElManawy, A Hammad, A Namani, XJ Wang, X Tang
Publication Date: 2020-04-23

Variant appearance in text: KRAS: G13D
PMID: 32327612
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Non-Coding RNAs in Lung Tumor Initiation and Progression.

International Journal Of Molecular Sciences
RM Santos, C Moreno, WC Zhang
Publication Date: 2020-04-16

Variant appearance in text: KRAS: G13D
PMID: 32316322
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BRAF and KRAS mutations in papillary thyroid carcinoma in the United Arab Emirates.

Plos One
S Al-Salam, C Sharma, B Afandi, K Al Dahmani, AS Al-Zahrani, A Al Shamsi, J Al Kaabi
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32315324
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Selective targeting of the oncogenic KRAS G12S mutant allele by CRISPR/Cas9 induces efficient tumor regression.

Theranostics
Q Gao, W Ouyang, B Kang, X Han, Y Xiong, R Ding, Y Li, F Wang, L Huang, L Chen, D Wang, X Dong, Z Zhang, Y Li, B Ze, Y Hou, H Yang, Y Ma, Y Gu, CC Chao
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32308773
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Use of an Integrated Pan-Cancer Oncology Enrichment Next-Generation Sequencing Assay to Measure Tumour Mutational Burden and Detect Clinically Actionable Variants.

Molecular Diagnosis & Therapy
V Pestinger, M Smith, T Sillo, JM Findlay, JF Laes, G Martin, G Middleton, P Taniere, AD Beggs
Publication Date: 2020-04-18

Variant appearance in text: KRAS: G13D
PMID: 32306292
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Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines.

Metabolomics : Official Journal Of The Metabolomic Society
D Varshavi, D Varshavi, N McCarthy, K Veselkov, HC Keun, JR Everett
Publication Date: 2020-04-16

Variant appearance in text: KRAS: G13D
PMID: 32300895
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Comprehensive review of targeted therapy for colorectal cancer.

Signal Transduction And Targeted Therapy
YH Xie, YX Chen, JY Fang
Publication Date: 2020-03-20

Variant appearance in text: KRAS: G13D
PMID: 32296018
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Ovarian mucinous tumors with mural nodules: immunohistochemical and molecular analysis of 3 cases.

Diagnostic Pathology
Y Shao, Q Liu, H Shi, B Lu
Publication Date: 2020-04-14

Variant appearance in text: KRAS: G13D
PMID: 32290854
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RAS/RAF mutations in tumor samples and cell-free DNA from plasma and bone marrow aspirates in multiple myeloma patients.

Journal Of Cancer
Q Li, HJ Huang, J Ma, Y Wang, Z Cao, G Karlin-Neumann, F Janku, Z Liu
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32284750
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Secondary Metabolites from the Culture of the Marine-derived Fungus Paradendryphiella salina PC 362H and Evaluation of the Anticancer Activity of Its Metabolite Hyalodendrin.

Marine Drugs
A Dezaire, CH Marchand, M Vallet, N Ferrand, S Chaouch, E Mouray, AK Larsen, M Sabbah, SD Lemaire, S Prado, AE Escargueil
Publication Date: 2020-04-03

Variant appearance in text: KRAS: G13D
PMID: 32260204
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Comprehensive genomic profile of cholangiocarcinomas in China.

Oncology Letters
W Tian, W Hu, X Shi, P Liu, X Ma, W Zhao, L Qu, S Zhang, W Shi, A Liu, J Cao
Publication Date: 2020-04

Variant appearance in text: KRAS: G13D
PMID: 32256810
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The Inhibition of Wnt Restrain KRASG12V-Driven Metastasis in Non-Small-Cell Lung Cancer.

Cancers
PS Hung, MH Huang, YY Kuo, JC Yang
Publication Date: 2020-03-31

Variant appearance in text: KRAS: G13D
PMID: 32244355
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Exosomal KRAS mutation promotes the formation of tumor-associated neutrophil extracellular traps and causes deterioration of colorectal cancer by inducing IL-8 expression.

Cell Communication And Signaling : Ccs
A Shang, C Gu, C Zhou, Y Yang, C Chen, B Zeng, J Wu, W Lu, W Wang, Z Sun, D Li
Publication Date: 2020-03-30

Variant appearance in text: KRAS: G13D
PMID: 32228650
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Harmonization of Next-Generation Sequencing Procedure in Italian Laboratories: A Multi-Institutional Evaluation of the SiRe® Panel.

Frontiers In Oncology
U Malapelle, F Pepe, P Pisapia, R Sgariglia, M Nacchio, C De Luca, R Lacalamita, S Tommasi, R Pinto, G Palomba, G Palmieri, D Vacirca, M Barberis, I Bottillo, P Grammatico, LR Grillo, V Costa, R Smeraglio, D Bruzzese, G Troncone
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32219061
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Comprehensive review of targeted therapy for colorectal cancer.

Signal Transduction And Targeted Therapy
YH Xie, YX Chen, JY Fang
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32219002
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An enzymatic on/off switch-mediated assay for KRAS hotspot point mutation detection of circulating tumor DNA.

Journal Of Clinical Laboratory Analysis
QL Wang, CL Zhou, YF Yin, L Xiao, Y Wang, K Li
Publication Date: 2020-03-24

Variant appearance in text: KRAS: G13D
PMID: 32207862
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Targeted sequencing analysis of cell-free DNA from metastatic non-small-cell lung cancer patients: clinical and biological implications.

Translational Lung Cancer Research
R Pasquale, L Forgione, C Roma, F Fenizia, F Bergantino, AM Rachiglio, A De Luca, M Gallo, MR Maiello, G Palumbo, A Morabito, R Azzaro, N Normanno
Publication Date: 2020-02

Variant appearance in text: KRAS: G13D
PMID: 32206554
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Analysis of tumor microenvironmental features to refine prognosis by T, N risk group in patients with stage III colon cancer (NCCTG N0147) (Alliance).

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology
H Lee, D Sha, NR Foster, Q Shi, SR Alberts, TC Smyrk, FA Sinicrope
Publication Date: 2020-01-25

Variant appearance in text: KRAS: 38G>A; G13D
PMID: 32165096
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IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models.

Plos One
A Gasilina, G Premnauth, P Gurjar, J Biesiada, S Hegde, D Milewski, G Ma, TV Kalin, E Merino, J Meller, W Seibel, JA Cancelas, LP Vinnedge, NN Nassar
Publication Date: 2020

Variant appearance in text: KRAS: G13D
PMID: 32163428
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Whole exome sequencing analysis of urine trans-renal tumour DNA in metastatic colorectal cancer patients.

Esmo Open
G Crisafulli, B Mussolin, A Cassingena, M Montone, A Bartolini, L Barault, A Martinetti, F Morano, F Pietrantonio, A Sartore-Bianchi, S Siena, F Di Nicolantonio, S Marsoni, A Bardelli, G Siravegna
Publication Date: 2019-11

Variant appearance in text: KRAS: G13D
PMID: 32149725
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Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000256078.4 c.38G>A p.Gly13Asp missense_variant 2/6 -
ENST00000311936.3 c.38G>A p.Gly13Asp missense_variant 2/5 -
ENST00000556131.1 c.38G>A p.Gly13Asp missense_variant 2/3 -
ENST00000557334.1 c.38G>A p.Gly13Asp missense_variant 2/3 -
NM_001369786.1 c.38G>A p.Gly13Asp missense_variant 2/6 -
NM_001369787.1 c.38G>A p.Gly13Asp missense_variant 2/5 -
NM_004985.5 c.38G>A p.Gly13Asp missense_variant 2/5 -
NM_033360.4 c.38G>A p.Gly13Asp missense_variant 2/6 -