Publications:

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Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications

Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI

Publication Date: 2023-02-08

Variant appearance in text: KRAS: G12E

PubMed Link: 36755027

Variant Present in the following documents:

• 41467_2023_36328_MOESM6_ESM.xlsx, sheet 1

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Identification of molecular subtypes in lung adenocarcinoma based on DNA methylation and gene expression profiling-a bioinformatic analysis.

Annals Of Translational Medicine

Wang, Shuying S; Liang, Xiaoxing X; Guo, Ruomi R; Gong, Jiao J; Zhong, Xiaolong X; Liu, Yulin Y; Wang, Deqing D; Hao, Yanmei Y; Hu, Bo B

Publication Date: 2022-08

Variant appearance in text: KRAS: G12E

PubMed Link: 36111050

Variant Present in the following documents:

• atm-10-16-882.pdf

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: KRAS: G12E

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

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Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA.

Ebiomedicine

Liu, Wenyang W; Li, Yifei Y; Tang, Yuan Y; Song, Qianqian Q; Wang, Jingjing J; Li, Ning N; Chen, Silin S; Shi, Jinming J; Wang, Shulian S; Li, Yexiong Y; Jiao, Yuchen Y; Zeng, Yixin Y; Jin, Jing J

Publication Date: 2022-04

Variant appearance in text: KRAS: G12E

PubMed Link: 35306340

Variant Present in the following documents:

• mmc3.xlsx, sheet 2

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Circulating tumor DNA predicts neoadjuvant immunotherapy efficacy and recurrence-free survival in surgical non-small cell lung cancer patients.

Translational Lung Cancer Research

Yue, Dongsheng D; Liu, Weiran W; Chen, Chen C; Zhang, Tao T; Ma, Yuchen Y; Cui, Longgang L; Gu, Yajun Y; Bei, Ting T; Zhao, Xiaochen X; Zhang, Bei B; Bai, Yuezong Y; Romero, Atocha A; Xu-Welliver, Meng M; Wang, Changli C; Zhang, Zhenfa Z; Zhang, Bin B

Publication Date: 2022-02

Variant appearance in text: KRAS: G12E

PubMed Link: 35280315

Variant Present in the following documents:

• tlcr-11-02-263-supplementary.pdf

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The landscape of driver mutations in cutaneous squamous cell carcinoma.

Npj Genomic Medicine

Chang, Darwin D; Shain, A Hunter AH

Publication Date: 2021-07-16

Variant appearance in text: KRAS: G12E

PubMed Link: 34272401

Variant Present in the following documents:

• 41525_2021_226_MOESM5_ESM.xlsx, sheet 1

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: KRAS: G12E

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

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Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non-small cell lung cancer: Analysis of over 8000 cases.

Cancer

Mack, Philip C PC; Banks, Kimberly C KC; Espenschied, Carin R CR; Burich, Rebekah A RA; Zill, Oliver A OA; Lee, Christine E CE; Riess, Jonathan W JW; Mortimer, Stefanie A SA; Talasaz, AmirAli A; Lanman, Richard B RB; Gandara, David R DR

Publication Date: 2020-07-15

Variant appearance in text: KRAS: G12E

PubMed Link: 32365229

Variant Present in the following documents:

• Main text
• CNCR-126-3219.pdf

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Precision medicine review: rare driver mutations and their biophysical classification.

Biophysical Reviews

Nussinov, Ruth R; Jang, Hyunbum H; Tsai, Chung-Jung CJ; Cheng, Feixiong F

Publication Date: 2019-02

Variant appearance in text: KRAS: G12E

PubMed Link: 30610579

Variant Present in the following documents:

• Main text
• 12551_2018_Article_496.pdf

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Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications

Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ

Publication Date: 2017-08-04

Variant appearance in text: KRAS: G12E

PubMed Link: 28775315

Variant Present in the following documents:

• 41467_2017_289_MOESM7_ESM.xlsx, sheet 1

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Circulating tumour DNA sequence analysis as an alternative to multiple myeloma bone marrow aspirates.

Nature Communications

Kis, Olena O; Kaedbey, Rayan R; Chow, Signy S; Danesh, Arnavaz A; Dowar, Mark M; Li, Tiantian T; Li, Zhihua Z; Liu, Jessica J; Mansour, Mark M; Masih-Khan, Esther E; Zhang, Tong T; Bratman, Scott V SV; Oza, Amit M AM; Kamel-Reid, Suzanne S; Trudel, Suzanne S; Pugh, Trevor J TJ

Publication Date: 2017-05-11

Variant appearance in text: KRAS: G12E

PubMed Link: 28492226

Variant Present in the following documents:

• ncomms15086-s3.xlsx, sheet 1

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Clinical applicability and cost of a 46-gene panel for genomic analysis of solid tumours: Retrospective validation and prospective audit in the UK National Health Service.

Plos Medicine

Hamblin, Angela A; Wordsworth, Sarah S; Fermont, Jilles M JM; Page, Suzanne S; Kaur, Kulvinder K; Camps, Carme C; Kaisaki, Pamela P; Gupta, Avinash A; Talbot, Denis D; Middleton, Mark M; Henderson, Shirley S; Cutts, Anthony A; Vavoulis, Dimitrios V DV; Housby, Nick N; Tomlinson, Ian I; Taylor, Jenny C JC; Schuh, Anna A

Publication Date: 2017-02

Variant appearance in text: KRAS: G12E

PubMed Link: 28196074

Variant Present in the following documents:

• pmed.1002230.s004.xlsx, sheet 2

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Genome-wide chemical mutagenesis screens allow unbiased saturation of the cancer genome and identification of drug resistance mutations.

Genome Research

Brammeld, Jonathan S JS; Petljak, Mia M; Martincorena, Inigo I; Williams, Steven P SP; Alonso, Luz Garcia LG; Dalmases, Alba A; Bellosillo, Beatriz B; Robles-Espinoza, Carla Daniela CD; Price, Stacey S; Barthorpe, Syd S; Tarpey, Patrick P; Alifrangis, Constantine C; Bignell, Graham G; Vidal, Joana J; Young, Jamie J; Stebbings, Lucy L; Beal, Kathryn K; Stratton, Michael R MR; Saez-Rodriguez, Julio J; Garnett, Mathew M; Montagut, Clara C; Iorio, Francesco F; McDermott, Ultan U

Publication Date: 2017-04

Variant appearance in text: KRAS: G12E

PubMed Link: 28179366

Variant Present in the following documents:

• supp_gr.213546.116_Supplemental_Table_S7.xlsx, sheet 1

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Genetic alterations of triple negative breast cancer by targeted next-generation sequencing and correlation with tumor morphology.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc

Weisman, Paul S PS; Ng, Charlotte K Y CK; Brogi, Edi E; Eisenberg, Rachel E RE; Won, Helen H HH; Piscuoglio, Salvatore S; De Filippo, Maria R MR; Ioris, Rafael R; Akram, Muzaffar M; Norton, Larry L; Weigelt, Britta B; Berger, Michael F MF; Reis-Filho, Jorge S JS; Wen, Hannah Y HY

Publication Date: 2016-05

Variant appearance in text: KRAS: G12E

PubMed Link: 26939876

Variant Present in the following documents:

• NIHMS752475-supplement-3.xlsx, sheet 1

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Deciphering Seed Sequence Based Off-Target Effects in a Large-Scale RNAi Reporter Screen for E-Cadherin Expression.

Plos One

Adams, Robert R; Nicke, Barbara B; Pohlenz, Hans-Dieter HD; Sohler, Florian F

Publication Date: 2015

Variant appearance in text: KRAS: G12E

PubMed Link: 26361354

Variant Present in the following documents:

• Main text

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BRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection.

British Journal Of Cancer

Schirripa, M M; Bergamo, F F; Cremolini, C C; Casagrande, M M; Lonardi, S S; Aprile, G G; Yang, D D; Marmorino, F F; Pasquini, G G; Sensi, E E; Lupi, C C; De Maglio, G G; Borrelli, N N; Pizzolitto, S S; Fasola, G G; Bertorelle, R R; Rugge, M M; Fontanini, G G; Zagonel, V V; Loupakis, F F; Falcone, A A

Publication Date: 2015-06-09

Variant appearance in text: KRAS: G12E

PubMed Link: 25942399

Variant Present in the following documents:

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Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets.

Nature Communications

Witkiewicz, Agnieszka K AK; McMillan, Elizabeth A EA; Balaji, Uthra U; Baek, GuemHee G; Lin, Wan-Chi WC; Mansour, John J; Mollaee, Mehri M; Wagner, Kay-Uwe KU; Koduru, Prasad P; Yopp, Adam A; Choti, Michael A MA; Yeo, Charles J CJ; McCue, Peter P; White, Michael A MA; Knudsen, Erik S ES

Publication Date: 2015-04-09

Variant appearance in text: KRAS: G12E

PubMed Link: 25855536

Variant Present in the following documents:

• ncomms7744-s2.xlsx, sheet 1

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A virtual pyrogram generator to resolve complex pyrosequencing results.

The Journal Of Molecular Diagnostics : Jmd

Chen, Guoli G; Olson, Matthew Theodore MT; O'Neill, Alan A; Norris, Alexis A; Beierl, Katie K; Harada, Shuko S; Debeljak, Marija M; Rivera-Roman, Keila K; Finley, Samantha S; Stafford, Amanda A; Gocke, Christopher David CD; Lin, Ming-Tseh MT; Eshleman, James Richard JR

Publication Date: 2012

Variant appearance in text: N/A

PubMed Link: 22316529

Variant Present in the following documents:

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High sensitivity of both sequencing and real-time PCR analysis of KRAS mutations in colorectal cancer tissue.

Journal Of Cellular And Molecular Medicine

Tol, Jolien J; Dijkstra, Jeroen R JR; Vink-Börger, Marianne E ME; Nagtegaal, Iris D ID; Punt, Cornelis J A CJ; Van Krieken, Johan H J M JH; Ligtenberg, Marjolijn J L MJ

Publication Date: 2010-08

Variant appearance in text: KRAS: 35_36delinsAG

PubMed Link: 19453520

Variant Present in the following documents:

• Main text
• jcmm0014-2122.pdf

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