Variant ID: 12-25398284-C-A

NM_033360.2(KRAS):c.35G>T;(p.Gly12Val)

This variant was identified in 2125 publications




Publications:


Cells of origin of lung cancers: lessons from mouse studies.

Genes & Development
G Ferone, MC Lee, J Sage, A Berns
Publication Date: 2020-08-01

Variant appearance in text: KRAS: G12V
PMID: 32747478
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Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine
J Li, W Jiang, J Wei, J Zhang, L Cai, M Luo, Z Wang, W Sun, S Wang, C Wang, C Dai, J Liu, G Wang, J Wang, Q Xu, Y Deng
Publication Date: 2020-08-01

Variant appearance in text: KRAS: G12V
PMID: 32738923
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Recurrent Neoantigens in Colorectal Cancer as Potential Immunotherapy Targets.

Biomed Research International
C Chen, S Liu, R Qu, B Li
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32733937
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Protein Arginine Methyltransferase 5 as a Therapeutic Target for KRAS Mutated Colorectal Cancer.

Cancers
D Shifteh, T Sapir, M Pahmer, A Haimowitz, S Goel, R Maitra
Publication Date: 2020-07-28

Variant appearance in text: KRAS: G12V
PMID: 32731506
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Distinct Molecular Landscape of Epstein-Barr Virus Associated Pulmonary Lymphoepithelioma-Like Carcinoma Revealed by Genomic Sequencing.

Cancers
SL Chau, JH Tong, C Chow, JS Kwan, RW Lung, LY Chung, EK Tin, SS Wong, AH Cheung, RW Lau, CS Ng, TS Mok, KW Lo, KF To
Publication Date: 2020-07-27

Variant appearance in text: KRAS: G12V
PMID: 32726920
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Multitarget stool DNA test compared with fecal occult blood test for colorectal cancer screening.

Oncology Letters
C Yang, W Wu, Y Yang, X Yang, J Sun, W Zhang, K Liu, H Ying, S Jiang, X Yu, Y Shi, Y Zhou, S Zhu, Y Xu, Y Ding, L Xie, B Cai, X Xin, P Chen, R Zhao, Y Wu
Publication Date: 2020-08

Variant appearance in text: KRAS: Gly12Val
PMID: 32724359
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The decisive role of molecular pathology in presumed somatic metastases of type II testicular germ cell tumors: report of 2 cases.

Diagnostic Pathology
MEG Kranendonk, WM Hackeng, GJA Offerhaus, FHM Morsink, GN Jonges, G Groenewegen, PJ Krijtenburg, HJ Klümpen, WWJ de Leng, LHJ Looijenga, LAA Brosens
Publication Date: 2020-07-25

Variant appearance in text: KRAS: Gly12Val
PMID: 32711552
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Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer.

Nature Communications
L Aubert, N Nandagopal, Z Steinhart, G Lavoie, S Nourreddine, J Berman, MK Saba-El-Leil, D Papadopoli, S Lin, T Hart, G Macleod, I Topisirovic, L Gaboury, CJ Fahrni, D Schramek, S Meloche, S Angers, PP Roux
Publication Date: 2020-07-24

Variant appearance in text: KRAS: G12V
PMID: 32709883
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Study of Ras Mutations' Prognostic Value in Metastatic Colorectal Cancer: STORIA Analysis.

Cancers
A Ottaiano, N Normanno, S Facchini, A Cassata, A Nappi, C Romano, L Silvestro, A De Stefano, AM Rachiglio, C Roma, MR Maiello, S Scala, P Delrio, F Tatangelo, A Di Mauro, G Botti, A Avallone, G Nasti
Publication Date: 2020-07-16

Variant appearance in text: KRAS: G12V
PMID: 32708575
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Identification of a Clinical Cutoff Value for Multiplex KRASG12/G13 Mutation Detection in Colorectal Adenocarcinoma Patients Using Digital Droplet PCR, and Comparison with Sanger Sequencing and PNA Clamping Assay.

Journal Of Clinical Medicine
KH Lee, TH Lee, MK Choi, IS Kwon, GE Bae, MK Yeo
Publication Date: 2020-07-18

Variant appearance in text: KRAS: G12V
PMID: 32708359
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Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR.

Scientific Reports
Y Ono, A Hayashi, C Maeda, M Suzuki, R Wada, H Sato, H Kawabata, T Okada, T Goto, H Karasaki, Y Mizukami, T Okumura
Publication Date: 2020-07-23

Variant appearance in text: KRAS: G12V
PMID: 32704002
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AMPK activation overcomes anti-EGFR antibody resistance induced by KRAS mutation in colorectal cancer.

Cell Communication And Signaling : Ccs
H Ye, Y Liu, K Wu, H Luo, L Cui
Publication Date: 2020-07-23

Variant appearance in text: KRAS: G12V
PMID: 32703218
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Applied precision medicine in metastatic pancreatic ductal adenocarcinoma.

Therapeutic Advances In Medical Oncology
H Taghizadeh, L Müllauer, RM Mader, M Schindl, GW Prager
Publication Date: 2020

Variant appearance in text: KRAS: Gly12Val
PMID: 32699558
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KRAS(G12C)-AMG 510 interaction dynamics revealed by all-atom molecular dynamics simulations.

Scientific Reports
T Pantsar
Publication Date: 2020-07-20

Variant appearance in text: KRAS: G12V
PMID: 32686745
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KRAS-associated microRNAs in colorectal cancer.

Oncology Reviews
H Ibrahim, YC Lim
Publication Date: 2020-07-06

Variant appearance in text: KRAS: G12V
PMID: 32685110
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The prognostic value of a Methylome-based Malignancy Density Scoring System to predict recurrence risk in early-stage Lung Adenocarcinoma.

Theranostics
L Yang, J Zhang, G Yang, H Xu, J Lin, L Shao, J Li, C Guo, Y Du, L Guo, X Li, H Han-Zhang, C Wang, S Chuai, J Ye, Q Kang, H Liu, J Ying, Y Wang
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32685009
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miRNAs-Based Molecular Signature for KRAS Mutated and Wild Type Colorectal Cancer: An Explorative Study.

Journal Of Immunology Research
E Milanesi, M Dobre, AI Bucuroiu, V Herlea, TE Manuc, A Salvi, G De Petro, M Manuc, G Becheanu
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32676506
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Personalized post-surgical care?-possible strategies for NSCLCs with EGFR mutation.

Translational Lung Cancer Research
K Suda
Publication Date: 2020-06

Variant appearance in text: KRAS: G12V
PMID: 32676308
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Relevance of Regulatory T Cells during Colorectal Cancer Development.

Cancers
JE Olguín, I Medina-Andrade, T Rodríguez, M Rodríguez-Sosa, LI Terrazas
Publication Date: 2020-07-14

Variant appearance in text: KRAS: G12V
PMID: 32674255
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BRAF and KRAS mutations in metastatic colorectal cancer: future perspectives for personalized therapy.

Gastroenterology Report
ZN Li, L Zhao, LF Yu, MJ Wei
Publication Date: 2020-06

Variant appearance in text: KRAS: G12V
PMID: 32665851
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Genomic characterization of Chinese ovarian clear cell carcinoma identifies driver genes by whole exome sequencing.

Neoplasia (New York, N.Y.)
Q Yang, C Zhang, Y Ren, H Yi, T Luo, F Xing, X Bai, L Cui, L Zhu, J Ouyang, P Jiang, W Fan, J Qiu, F Wang, X Xing, Z Zhang, X Zhang, R Zhang
Publication Date: 2020-07-07

Variant appearance in text: KRAS: G12V
PMID: 32650224
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KRAS Mutation-Responsive miR-139-5p inhibits Colorectal Cancer Progression and is repressed by Wnt Signaling.

Theranostics
F Du, T Cao, H Xie, T Li, L Sun, H Liu, H Guo, X Wang, Q Liu, T Kim, JL Franklin, R Graves-Deal, W Han, Z Tian, M Ge, Y Nie, D Fan, RJ Coffey, Y Lu, X Zhao
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32641995
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Mutation profile of primary subungual melanomas in Caucasians.

Oncotarget
A Borkowska, A Szumera-Ciećkiewicz, M Spałek, P Teterycz, A Czarnecka, A Kowalik, P Rutkowski
Publication Date: 2020-06-23

Variant appearance in text: KRAS: 35G>T; G12V
PMID: 32637031
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Could Protons and Carbon Ions Be the Silver Bullets Against Pancreatic Cancer?

International Journal Of Molecular Sciences
C Huart, JW Chen, B Le Calvé, C Michiels, AC Wéra
Publication Date: 2020-07-04

Variant appearance in text: KRAS: G12V
PMID: 32635552
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T-Cell Gene Therapy in Cancer Immunotherapy: Why It Is No Longer Just CARs on The Road.

Cells
MD Crowther, IM Svane, Ö Met
Publication Date: 2020-06-30

Variant appearance in text: KRAS: G12V
PMID: 32630096
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Germline and Somatic Pharmacogenomics to Refine Rectal Cancer Patients Selection for Neo-Adjuvant Chemoradiotherapy.

Frontiers In Pharmacology
E De Mattia, R Roncato, E Palazzari, G Toffoli, E Cecchin
Publication Date: 2020

Variant appearance in text: KRAS: Gly12Val
PMID: 32625092
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Evaluation of circulating tumor DNA as a biomarker in pancreatic cancer with liver metastasis.

Plos One
Y Uesato, N Sasahira, M Ozaka, T Sasaki, M Takatsuki, H Zembutsu
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32614932
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Implementing cell-free DNA of pancreatic cancer patient-derived organoids for personalized oncology.

Jci Insight
Z Dantes, HY Yen, N Pfarr, C Winter, K Steiger, A Muckenhuber, A Hennig, S Lange, T Engleitner, R Öllinger, R Maresch, F Orben, I Heid, GA Kaissis, K Shi, GJ Topping, F Stögbauer, M Wirth, K Peschke, A Papargyriou, M Rezaee-Oghazi, K Feldmann, APG Schäfer, R Ranjan, C Lubeseder-Martellato, DE Stange, T Welsch, ME Martignoni, GO Ceyhan, H Friess, A Herner, L Liotta, M Treiber, G von Figura, M Abdelhafez, P Klare, C Schlag, H Algül, JT Siveke, RF Braren, G Weirich, W Weichert, D Saur, R Rad, R Schmid, G Schneider, M Reichert
Publication Date: 2020-07-02

Variant appearance in text: KRAS: G12V
PMID: 32614802
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Transgenic T-cell receptor immunotherapy for cancer: building on clinical success.

Therapeutic Advances In Vaccines And Immunotherapy
N Oppermans, G Kueberuwa, RE Hawkins, JS Bridgeman
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32613155
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Molecular matching and treatment strategies for advanced stage lung cancer at Dartmouth-Hitchcock Medical Center: A three-year review of a Molecular Tumor Board.

Practical Laboratory Medicine
EB Bernhardt, MD Chamberlin, IP Gorlov, FB de Abreu, KJ Bloch, JD Peterson, GJ Tsongalis, K Shirai, KH Dragnev, TW Miller, LJ Tafe
Publication Date: 2020-08

Variant appearance in text: KRAS: G12V
PMID: 32613070
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Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe.

Cell Death & Disease
B Gastl, K Klotz-Noack, B Klinger, S Ispasanie, KHF Salib, J Zuber, S Mamlouk, N Bublitz, N Blüthgen, D Horst, M Morkel, R Schäfer, C Sers
Publication Date: 2020-07-01

Variant appearance in text: KRAS: G12V
PMID: 32612138
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Targeting Altered Energy Metabolism in Colorectal Cancer: Oncogenic Reprogramming, the Central Role of the TCA Cycle and Therapeutic Opportunities.

Cancers
C Neitzel, P Demuth, S Wittmann, J Fahrer
Publication Date: 2020-06-29

Variant appearance in text: KRAS: G12V
PMID: 32610612
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Clinical characteristics and prognostic value of the KRAS G12C mutation in Chinese non-small cell lung cancer patients.

Biomarker Research
SY Liu, H Sun, JY Zhou, GL Jie, Z Xie, Y Shao, X Zhang, JY Ye, CX Chen, XC Zhang, Q Zhou, JJ Yang, YL Wu
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32607238
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Inhibition of lncRNA PART1 Chemosensitizes Wild Type but Not KRAS Mutant NSCLC Cells.

Cancer Management And Research
SC Chen, YZ Diao, ZH Zhao, XL Li
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32606939
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Undifferentiated carcinoma with osteoclast-like giant cells of the pancreas harboring KRAS and BRCA mutations: case report and whole exome sequencing analysis.

Bmc Gastroenterology
G Yang, J Yin, K Ou, Q Du, W Ren, Y Jin, L Peng, L Yang
Publication Date: 2020-06-26

Variant appearance in text: KRAS: G12V
PMID: 32590950
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Clinicopathological Characteristics and Mutation Spectrum of Colorectal Adenocarcinoma With Mucinous Component in a Chinese Cohort: Comparison With Classical Adenocarcinoma.

Frontiers In Oncology
J Chen, L Zhou, J Gao, T Lu, J Wang, H Wu, Z Liang
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32582557
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Genetic Tracing of Clonal Expansion and Progression of Pancreatic Ductal Adenocarcinoma: A Case Report and Multi-Region Sequencing Analysis.

Frontiers In Oncology
S Tachibana, Y Mizukami, Y Ono, Y Sugiyama, T Okada, A Kitazaki, J Sasajima, M Tominaga, J Sakamoto, K Kimura, Y Omori, T Furukawa, T Kimura, S Tanaka, K Nagashima, H Karasaki, T Ohta, T Okumura
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32582528
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Active Compound of Pharbitis Semen (Pharbitis nil Seeds) Suppressed KRAS-Driven Colorectal Cancer and Restored Muscle Cell Function during Cancer Progression.

Molecules (Basel, Switzerland)
J Song, H Seo, MR Kim, SJ Lee, S Ahn, M Song
Publication Date: 2020-06-22

Variant appearance in text: KRAS: G12V
PMID: 32580297
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Genome-wide DNA methylation analysis of KRAS mutant cell lines.

Scientific Reports
BY Tew, JK Durand, KL Bryant, TK Hayes, S Peng, NL Tran, GC Gooden, DN Buckley, CJ Der, AS Baldwin, B Salhia
Publication Date: 2020-06-23

Variant appearance in text: KRAS: G12V
PMID: 32576853
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Ex vivo modelling of drug efficacy in a rare metastatic urachal carcinoma.

Bmc Cancer
R Mäkelä, A Arjonen, V Härmä, N Rintanen, L Paasonen, T Paprotka, K Rönsch, T Kuopio, J Kononen, JK Rantala
Publication Date: 2020-06-23

Variant appearance in text: KRAS: G12V
PMID: 32576176
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FAM83G Is a Novel Inducer of Apoptosis.

Molecules (Basel, Switzerland)
J Okada, N Sunaga, E Yamada, T Saito, A Ozawa, Y Nakajima, K Okada, JE Pessin, S Okada, M Yamada
Publication Date: 2020-06-18

Variant appearance in text: KRAS: G12V
PMID: 32570757
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Resection for pancreatic cancer metastases contributes to survival: A case report with sequential tumor genotype profiling during the long-term postoperative course.

Medicine
H Sato, J Sasajima, T Okada, A Hayashi, H Kawabata, T Goto, K Koizumi, N Tamamura, H Tanabe, M Fujiya, SI Chiba, M Tanino, Y Ono, Y Mizukami, T Okumura
Publication Date: 2020-06-19

Variant appearance in text: KRAS: G12V
PMID: 32569179
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Histology and its prognostic effect on KRAS-mutated colorectal carcinomas in Korea.

Oncology Letters
HS Lee, DY Hwang, HS Han
Publication Date: 2020-07

Variant appearance in text: KRAS: G12V
PMID: 32565990
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Evidence for endothelial-to-mesenchymal transition in human brain arteriovenous malformations.

Clinical And Translational Medicine
LD Shoemaker, AK McCormick, BM Allen, SD Chang
Publication Date: 2020-06-21

Variant appearance in text: KRAS: G12V
PMID: 32564509
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Isoprenylcysteine carboxylmethyltransferase is required for the impact of mutant KRAS on TAZ protein level and cancer cell self-renewal.

Oncogene
TF Chai, KA Manu, PJ Casey, M Wang
Publication Date: 2020-06-19

Variant appearance in text: KRAS: G12V
PMID: 32561852
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Targeting KRAS Mutant Non-Small-Cell Lung Cancer: Past, Present and Future.

International Journal Of Molecular Sciences
IZ Uras, HP Moll, E Casanova
Publication Date: 2020-06-17

Variant appearance in text: KRAS: G12V
PMID: 32560574
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Germline Mutation Enrichment in Pathways Controlling Endothelial Cell Homeostasis in Patients with Brain Arteriovenous Malformation: Implication for Molecular Diagnosis.

International Journal Of Molecular Sciences
C Scimone, F Granata, M Longo, E Mormina, C Turiaco, AA Caragliano, L Donato, A Sidoti, R D'Angelo
Publication Date: 2020-06-17

Variant appearance in text: KRAS: 35G>T; Gly12Val
PMID: 32560555
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Complex Oncological Decision-Making Utilizing Fast-and-Frugal Trees in a Community Setting-Role of Academic and Hybrid Modeling.

Journal Of Clinical Medicine
R Salgia, I Mambetsariev, T Tan, A Schwer, DP Pearlstein, H Chehabi, A Baroz, J Fricke, R Pharaon, H Romo, T Waddington, R Babikian, L Buck, P Kulkarni, M Cianfrocca, B Djulbegovic, SK Pal
Publication Date: 2020-06-16

Variant appearance in text: KRAS: G12V
PMID: 32560187
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Characterizing the Motility of Chemotherapeutics-Treated Acute Lymphoblastic Leukemia Cells by Time-Lapse Imaging.

Cells
HC Liu, EJ Gang, HN Kim, Y Ruan, H Ogana, Z Wan, H Bönig, KK Shung, YM Kim
Publication Date: 2020-06-16

Variant appearance in text: KRAS: G12V
PMID: 32560076
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A novel hotspot and rare somatic mutation p.A138V, at TP53 is associated with poor survival of pancreatic ductal and periampullary adenocarcinoma patients.

Molecular Medicine (Cambridge, Mass.)
G Saha, R Singh, A Mandal, S Das, E Chattopadhyay, P Panja, P Roy, N DeSarkar, S Gulati, S Ghatak, S Ghosh, S Banerjee, B Roy, S Ghosh, D Chaudhuri, N Arora, NK Biswas, N Sikdar
Publication Date: 2020-06-17

Variant appearance in text: KRAS: G12V
PMID: 32552660
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Somatic Gain of KRAS Function in the Endothelium is Sufficient to Cause Vascular Malformations that Require MEK but not PI3K Signaling.

Circulation Research
JE Fish, CP Flores-Suarez, E Boudreau, AM Herman, MC Gutierrez, D Gustafson, PV DiStefano, M Cui, Z Chen, K Berman De Ruiz, TS Schexnayder, CS Ward, I Radovanovic, JD Wythe
Publication Date: 2020-06-17

Variant appearance in text: KRAS: G12V
PMID: 32552404
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Application of targeted next generation sequencing for the mutational profiling of patients with acute lymphoblastic leukemia.

Journal Of Medical Biochemistry
D Janic, J Peric, T Karan-Djurasevic, T Kostic, I Marjanovic, B Stanic, N Pejanovic, L Dokmanovic, J Lazic, N Krstovski, M Virijevic, D Tomin, A Vidovic, N Suvajdzic-Vukovic, S Pavlovic, N Tosic
Publication Date: 2020-01-10

Variant appearance in text: KRAS: 35G>T; G12V; rs121913529
PMID: 32550823
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CUX1, A Controversial Player in Tumor Development.

Frontiers In Oncology
N Liu, Q Sun, L Wan, X Wang, Y Feng, J Luo, H Wu
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32547943
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The Diagnosis, Treatment, Prognosis and Molecular Pathology of Borderline Ovarian Tumors: Current Status and Perspectives.

Cancer Management And Research
Y Sun, J Xu, X Jia
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32547202
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Anti-PD-1 Therapy Achieved Disease Control After Multiline Chemotherapy in Unresectable KRAS-Positive Hepatoid Lung Adenocarcinoma: A Case Report and Literature Review.

Oncotargets And Therapy
L Chen, X Han, Y Gao, Q Zhao, Y Wang, Y Jiang, S Liu, X Wu, L Miao
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32547068
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A Driver Never Works Alone-Interplay Networks of Mutant p53, MYC, RAS, and Other Universal Oncogenic Drivers in Human Cancer.

Cancers
M Grzes, M Oron, Z Staszczak, A Jaiswar, M Nowak-Niezgoda, D Walerych
Publication Date: 2020-06-11

Variant appearance in text: KRAS: G12V
PMID: 32545208
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Peripheral type squamous cell carcinoma of the lung: clinicopathologic characteristics in comparison to the central type.

Journal Of Pathology And Translational Medicine
YE Sung, U Cho, KY Lee
Publication Date: 2020-06-17

Variant appearance in text: KRAS: 35G>T; Gly12Val
PMID: 32544984
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Mir34a constrains pancreatic carcinogenesis.

Scientific Reports
A Hidalgo-Sastre, C Lubeseder-Martellato, T Engleitner, K Steiger, S Zhong, J Desztics, R Öllinger, R Rad, RM Schmid, H Hermeking, JT Siveke, G von Figura
Publication Date: 2020-06-15

Variant appearance in text: KRAS: G12V
PMID: 32541781
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Traditional serrated adenoma has two distinct genetic pathways for molecular tumorigenesis with potential neoplastic progression.

Journal Of Gastroenterology
Y Tanaka, M Eizuka, N Uesugi, K Kawasaki, H Yamano, H Suzuki, T Matsumoto, T Sugai
Publication Date: 2020-06-13

Variant appearance in text: KRAS: G12V
PMID: 32535664
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MICA Allele Facilitates the Metastasis of KRAS-Mutant Colorectal Cancer.

Frontiers In Genetics
W Ding, Y Ma, W Zhu, W Pu, J Zhang, F Qian, Y Zhou, Y Deng, S Guo, J Wang, X Zhou
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32528529
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A novel sensitive detection method for DNA methylation in circulating free DNA of pancreatic cancer.

Plos One
K Shinjo, K Hara, G Nagae, T Umeda, K Katsushima, M Suzuki, Y Murofushi, Y Umezu, I Takeuchi, S Takahashi, Y Okuno, K Matsuo, H Ito, S Tajima, H Aburatani, K Yamao, Y Kondo
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32520974
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Detection of Colorectal Cancer and Advanced Adenoma by Liquid Biopsy (Decalib Study): The ddPCR Challenge.

Cancers
A Junca, G Tachon, C Evrard, C Villalva, E Frouin, L Karayan-Tapon, D Tougeron
Publication Date: 2020-06-06

Variant appearance in text: KRAS: G12V
PMID: 32517177
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Drug-Drug Interactions of Irinotecan, 5-Fluorouracil, Folinic Acid and Oxaliplatin and Its Activity in Colorectal Carcinoma Treatment.

Molecules (Basel, Switzerland)
M Zoetemelk, GM Ramzy, M Rausch, P Nowak-Sliwinska
Publication Date: 2020-06-04

Variant appearance in text: KRAS: G12V
PMID: 32512790
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Metabolic Heterogeneity in Patient Tumor-Derived Organoids by Primary Site and Drug Treatment.

Frontiers In Oncology
JT Sharick, CM Walsh, CM Sprackling, CA Pasch, DL Pham, K Esbona, A Choudhary, R Garcia-Valera, ME Burkard, SM McGregor, KA Matkowskyj, AA Parikh, IM Meszoely, MC Kelley, S Tsai, DA Deming, MC Skala
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32500020
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An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development.

Nature Communications
S Shankar, JC Tien, RF Siebenaler, S Chugh, VL Dommeti, S Zelenka-Wang, XM Wang, IJ Apel, J Waninger, S Eyunni, A Xu, M Mody, A Goodrum, Y Zhang, JJ Tesmer, R Mannan, X Cao, P Vats, S Pitchiaya, SJ Ellison, J Shi, C Kumar-Sinha, HC Crawford, AM Chinnaiyan
Publication Date: 2020-06-04

Variant appearance in text: KRAS: G12V
PMID: 32499547
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Blood-based Genomic Profiling of Circulating Tumor DNA from Patients with Advanced Pancreatic Cancer and its Value to Guide Clinical Treatment.

Journal Of Cancer
H Li, Y Di, J Li, Y Jiang, H He, L Yao, J Gu, J Lu, J Song, S Chen, S Cai, C Jin, Z Yuan, D Fu
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32489450
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Metabolic Escape Routes of Cancer Stem Cells and Therapeutic Opportunities.

Cancers
A Turdo, G Porcelli, C D'Accardo, SD Franco, F Verona, S Forte, D Giuffrida, L Memeo, M Todaro, G Stassi
Publication Date: 2020-05-31

Variant appearance in text: KRAS: G12V
PMID: 32486505
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A H-REV107 Peptide Inhibits Tumor Growth and Interacts Directly with Oncogenic KRAS Mutants.

Cancers
CW Han, MS Jeong, SC Ha, SB Jang
Publication Date: 2020-05-30

Variant appearance in text: KRAS: G12V
PMID: 32486141
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A novel NGS-based microsatellite instability (MSI) status classifier with 9 loci for colorectal cancer patients.

Journal Of Translational Medicine
K Zheng, H Wan, J Zhang, G Shan, N Chai, D Li, N Fang, L Liu, J Zhang, R Du, Q Wu, X Li, C Zhang
Publication Date: 2020-05-28

Variant appearance in text: KRAS: G12V
PMID: 32466784
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New insights into classification and risk stratification of encapsulated thyroid tumors with a predominantly papillary architecture.

Journal Of Pathology And Translational Medicine
CK Jung, SY Park, JH Kim, K Kakudo
Publication Date: 2020-05

Variant appearance in text: KRAS: G12V
PMID: 32460473
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Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses.

Ebiomedicine
G Raimondi, A Mato-Berciano, S Pascual-Sabater, M Rovira-Rigau, M Cuatrecasas, C Fondevila, S Sánchez-Cabús, H Begthel, SF Boj, H Clevers, C Fillat
Publication Date: 2020-05-24

Variant appearance in text: KRAS: G12V
PMID: 32460166
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The Quest for Improving Treatment of Cancer of Unknown Primary (CUP) Through Molecularly-Driven Treatments: A Systematic Review.

Frontiers In Oncology
R Lombardo, F Tosi, A Nocerino, K Bencardino, V Gambi, R Ricotta, F Spina, S Siena, A Sartore-Bianchi
Publication Date: 2020

Variant appearance in text: KRAS: G12V
PMID: 32457826
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Small Molecule KRAS Inhibitors: The Future for Targeted Pancreatic Cancer Therapy?

Cancers
J Gillson, Y Ramaswamy, G Singh, AA Gorfe, N Pavlakis, J Samra, A Mittal, S Sahni
Publication Date: 2020-05-24

Variant appearance in text: KRAS: G12V
PMID: 32456277
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Application of Next-Generation Sequencing for the Genomic Characterization of Patients with Smoldering Myeloma.

Cancers
M Manzoni, V Marchica, P Storti, B Ziccheddu, G Sammarelli, G Todaro, F Pelizzoni, S Salerio, L Notarfranchi, A Pompa, L Baldini, N Bolli, A Neri, N Giuliani, M Lionetti
Publication Date: 2020-05-23

Variant appearance in text: KRAS: G12V
PMID: 32456143
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Experimental Treatment of Mucinous Peritoneal Metastases Using Patient-Derived Xenograft Models.

Translational Oncology
KG Fleten, C Lund-Andersen, S Waagene, TW Abrahamsen, Y Mørch, K Boye, A Torgunrud, K Flatmark
Publication Date: 2020-05-21

Variant appearance in text: KRAS: G12V
PMID: 32447231
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Metformin selectively inhibits metastatic colorectal cancer with the KRAS mutation by intracellular accumulation through silencing MATE1.

Proceedings Of The National Academy Of Sciences Of The United States Of America
J Xie, L Xia, W Xiang, W He, H Yin, F Wang, T Gao, W Qi, Z Yang, X Yang, T Zhou, G Gao
Publication Date: 2020-05-22

Variant appearance in text: KRAS: G12V
PMID: 32444490
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Molecular testing on bronchial washings for the diagnosis and predictive assessment of lung cancer.

Molecular Oncology
R Roncarati, L Lupini, E Miotto, E Saccenti, S Mascetti, L Morandi, C Bassi, D Rasio, E Callegari, V Conti, R Rinaldi, G Lanza, R Gafà, A Papi, A Frassoldati, S Sabbioni, F Ravenna, GL Casoni, M Negrini
Publication Date: 2020-05-22

Variant appearance in text: KRAS: G12V
PMID: 32441866
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Azasteroid Alkylators as Dual Inhibitors of AKT and ERK Signaling for the Treatment of Ovarian Carcinoma.

Cancers
P Dalezis, E Geromichalou, A Polonifi, S Sagredou, N Nikoleousakos, M Nikolaou, V Sarli, MI Panayiotidis, DT Trafalis
Publication Date: 2020-05-16

Variant appearance in text: KRAS: G12V
PMID: 32429466
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Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000256078.4 c.35G>T p.Gly12Val missense_variant 2/6 -
ENST00000311936.3 c.35G>T p.Gly12Val missense_variant 2/5 -
ENST00000556131.1 c.35G>T p.Gly12Val missense_variant 2/3 -
ENST00000557334.1 c.35G>T p.Gly12Val missense_variant 2/3 -
NM_001369786.1 c.35G>T p.Gly12Val missense_variant 2/6 -
NM_001369787.1 c.35G>T p.Gly12Val missense_variant 2/5 -
NM_004985.5 c.35G>T p.Gly12Val missense_variant 2/5 -
NM_033360.4 c.35G>T p.Gly12Val missense_variant 2/6 -