Publications:

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The CD73 immune checkpoint promotes tumor cell metabolic fitness.

Elife

Allard, David D; Cousineau, Isabelle I; Ma, Eric H EH; Allard, Bertrand B; Bareche, Yacine Y; Fleury, Hubert H; Stagg, John J

Publication Date: 2023-06-01

Variant appearance in text: KRAS: G12V

PubMed Link: 37261423

Variant Present in the following documents:

• elife-84508.pdf

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RAS-targeted cancer therapy: Advances in drugging specific mutations.

Medcomm

Liu, Cen C; Ye, Danyang D; Yang, Hongliu H; Chen, Xu X; Su, Zhijun Z; Li, Xia X; Ding, Mei M; Liu, Yonggang Y

Publication Date: 2023-06

Variant appearance in text: KRAS: G12V

PubMed Link: 37250144

Variant Present in the following documents:

• Main text
• MCO2-4-e285.pdf

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Effect of Secretion Efficiency of Mutant KRAS Neoantigen by Lactococcus lactis on the Immune Response of a Mucosal Vaccine Delivery Vehicle Targeting Colorectal Cancer.

International Journal Of Molecular Sciences

Alias, Nur Aqlili Riana NAR; Hoo, Winfrey Pui Yee WPY; Siak, Pui Yan PY; Othman, Siti Sarah SS; Mohammed Alitheen, Noorjahan Banu NB; In, Lionel Lian Aun LLA; Abdul Rahim, Raha R; Song, Adelene Ai-Lian AA

Publication Date: 2023-05-18

Variant appearance in text: KRAS: G12V

PubMed Link: 37240273

Variant Present in the following documents:

• Main text
• ijms-24-08928.pdf

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Clinicopathological Characteristics and Mutational Landscape of APC, HOXB13, and KRAS among Rwandan Patients with Colorectal Cancer.

Current Issues In Molecular Biology

Manirakiza, Felix F; Rutaganda, Eric E; Yamada, Hidetaka H; Iwashita, Yuji Y; Rugwizangoga, Belson B; Seminega, Benoit B; Dusabejambo, Vincent V; Ntakirutimana, Gervais G; Ruhangaza, Deogratias D; Uwineza, Annette A; Shinmura, Kazuya K; Sugimura, Haruhiko H

Publication Date: 2023-05-16

Variant appearance in text: KRAS: Gly12Val

PubMed Link: 37232746

Variant Present in the following documents:

• Main text
• cimb-45-00277.pdf

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Targeting small GTPases: emerging grasps on previously untamable targets, pioneered by KRAS.

Signal Transduction And Targeted Therapy

Yin, Guowei G; Huang, Jing J; Petela, Johnny J; Jiang, Hongmei H; Zhang, Yuetong Y; Gong, Siqi S; Wu, Jiaxin J; Liu, Bei B; Shi, Jianyou J; Gao, Yijun Y

Publication Date: 2023-05-23

Variant appearance in text: KRAS: G12V

PubMed Link: 37221195

Variant Present in the following documents:

• Main text
• 41392_2023_Article_1441.pdf

View BVdb publication page

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Determinants of tumor immune evasion: the role of T cell exposed motif frequency and mutant amino acid exposure.

Frontiers In Immunology

Homan, E Jane EJ; Bremel, Robert D RD

Publication Date: 2023

Variant appearance in text: KRAS: G12V

PubMed Link: 37215122

Variant Present in the following documents:

• Main text
• fimmu-14-1155679.pdf

View BVdb publication page

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Efficacy and safety of combined immunotherapy and antiangiogenic therapy for advanced non-small cell lung cancer: a real-world observation study.

Bmc Pulmonary Medicine

Ma, Ke K; Guo, Qianqian Q; Li, Xingya X

Publication Date: 2023-05-19

Variant appearance in text: KRAS: G12V

PubMed Link: 37208639

Variant Present in the following documents:

• Main text
• 12890_2023_Article_2470.pdf

View BVdb publication page

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Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.

Biorxiv : The Preprint Server For Biology

Ratnasinghe, Brian D BD; Haque, Neshatul N; Wagenknecht, Jessica B JB; Jensen, Davin R DR; Esparza, Guadalupe V GV; Leverence, Elise N EN; De Assuncao, Thiago Milech TM; Mathison, Angela J AJ; Lomberk, Gwen G; Smith, Brian C BC; Volkman, Brian F BF; Urrutia, Raul R; Zimmermann, Michael T MT

Publication Date: 2023-04-28

Variant appearance in text: KRAS: G12V

PubMed Link: 37207265

Variant Present in the following documents:

• Main text
• nihpp-2023.04.28.536249v1.pdf
• media-1.pdf

View BVdb publication page

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The role of molecular testing in pancreatic cancer.

Therapeutic Advances In Gastroenterology

Zhen, David B DB; Safyan, Rachael A RA; Konick, Eric Q EQ; Nguyen, Ryan R; Prichard, Colin C CC; Chiorean, E Gabriela EG

Publication Date: 2023

Variant appearance in text: KRAS: G12V

PubMed Link: 37197396

Variant Present in the following documents:

• Main text
• 10.1177_17562848231171456.pdf

View BVdb publication page

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Intrinsic features of the cancer cell as drivers of immune checkpoint blockade response and refractoriness.

Frontiers In Immunology

Ursino, Chiara C; Mouric, Cécile C; Gros, Laurent L; Bonnefoy, Nathalie N; Faget, Julien J

Publication Date: 2023

Variant appearance in text: KRAS: G12V

PubMed Link: 37180110

Variant Present in the following documents:

• fimmu-14-1170321.pdf

View BVdb publication page

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Krüppel-like Factors 4 and 5 in Colorectal Tumorigenesis.

Cancers

Lee, Esther E; Cheung, Jacky J; Bialkowska, Agnieszka B AB

Publication Date: 2023-04-24

Variant appearance in text: KRAS: G12V

PubMed Link: 37173904

Variant Present in the following documents:

• Main text
• cancers-15-02430.pdf

View BVdb publication page

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The efficacy of immune checkpoint inhibitors in biliary tract cancer with KRAS mutation.

Therapeutic Advances In Gastroenterology

Jeong, Sun Young SY; Hong, Jung Yong JY; Park, Joon Oh JO; Park, Young Suk YS; Lim, Ho Yeong HY; Jang, Jae Yeon JY; Jeon, Youngkyung Y; Kim, Seung Tae ST

Publication Date: 2023

Variant appearance in text: KRAS: G12V

PubMed Link: 37163165

Variant Present in the following documents:

• Main text
• 10.1177_17562848231170484.pdf

View BVdb publication page

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KRAS mutation: The booster of pancreatic ductal adenocarcinoma transformation and progression.

Frontiers In Cell And Developmental Biology

Zhang, Zining Z; Zhang, Heng H; Liao, Xiang X; Tsai, Hsiang-I HI

Publication Date: 2023

Variant appearance in text: KRAS: G12V

PubMed Link: 37152291

Variant Present in the following documents:

• Main text
• fcell-11-1147676.pdf

View BVdb publication page

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Contribution of Somatic Ras/Raf/Mitogen-Activated Protein Kinase Variants in the Hippocampus in Drug-Resistant Mesial Temporal Lobe Epilepsy.

Jama Neurology

Khoshkhoo, Sattar S; Wang, Yilan Y; Chahine, Yasmine Y; Erson-Omay, E Zeynep EZ; Robert, Stephanie M SM; Kiziltug, Emre E; Damisah, Eyiyemisi C EC; Nelson-Williams, Carol C; Zhu, Guangya G; Kong, Wenna W; Huang, August Yue AY; Stronge, Edward E; Phillips, H Westley HW; Chhouk, Brian H BH; Bizzotto, Sara S; Chen, Ming Hui MH; Adikari, Thiuni N TN; Ye, Zimeng Z; Witkowski, Tom T; Lai, Dulcie D; Lee, Nadine N; Lokan, Julie J; Scheffer, Ingrid E IE; Berkovic, Samuel F SF; Haider, Shozeb S; Hildebrand, Michael S MS; Yang, Edward E; Gunel, Murat M; Lifton, Richard P RP; Richardson, R Mark RM; Blümcke, Ingmar I; Alexandrescu, Sanda S; Huttner, Anita A; Heinzen, Erin L EL; Zhu, Jidong J; Poduri, Annapurna A; DeLanerolle, Nihal N; Spencer, Dennis D DD; Lee, Eunjung Alice EA; Walsh, Christopher A CA; Kahle, Kristopher T KT

Publication Date: 2023-05-01

Variant appearance in text: KRAS: 35G>T; G12V

PubMed Link: 37126322

Variant Present in the following documents:

• Main text
• jamaneurol-e230473.pdf

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Establishment of patient-derived tumor organoids to functionally inform treatment decisions in metastatic colorectal cancer.

Esmo Open

Martini, G G; Belli, V V; Napolitano, S S; Ciaramella, V V; Ciardiello, D D; Belli, A A; Izzo, F F; Avallone, A A; Selvaggi, F F; Menegon Tasselli, F F; Santaniello, W W; Franco, R R; Puig, I I; Ramirez, L L; Chicote, I I; Mancuso, F F; Caratu, G G; Serres, X X; Fasani, R R; Jimenez, J J; Ros, J J; Baraibar, I I; Mulet, N N; Della Corte, C M CM; Troiani, T T; Vivancos, A A; Dienstmann, R R; Elez, E E; Palmer, H G HG; Tabernero, J J; Martinelli, E E; Ciardiello, F F; Argilés, G G

Publication Date: 2023-04-26

Variant appearance in text: KRAS: G12V

PubMed Link: 37119788

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Planning adaptive treatment by longitudinal response assessment implementing MR imaging, liquid biopsy and analysis of microenvironment during neoadjuvant treatment of rectal cancer (PRIMO).

Medicine

Wurschi, Georg W GW; Güllmar, Daniel D; Gaßler, Nikolaus N; Clement, Joachim J; Kesselmeier, Miriam M; Müller-Wurschi, Julia J JJ; Settmacher, Utz U; Mothes, Henning H; Helfritzsch, Herry H; Liebe, Yves Y; Franiel, Tobias T; Mäurer, Matthias A MA; Ernst, Thomas T; Nicolay, Nils H NH; Wittig, Andrea A

Publication Date: 2023-04-25

Variant appearance in text: KRAS: G12V

PubMed Link: 37115093

Variant Present in the following documents:

• Main text
• medi-102-e33575.pdf

View BVdb publication page

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CodeBreak 200: Sotorasib Has Not Broken the KRASG12C Enigma Code.

Lung Cancer (Auckland, N.Z.)

Zhang, Shannon S SS; Lee, Alexandria A; Nagasaka, Misako M

Publication Date: 2023

Variant appearance in text: KRAS: G12V

PubMed Link: 37101895

Variant Present in the following documents:

• Main text
• lctt-14-27.pdf

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Combining the amplification refractory mutation system and high-resolution melting analysis for KRAS mutation detection in clinical samples.

Analytical And Bioanalytical Chemistry

Oliveira, Beatriz B BB; Costa, Beatriz B; Morão, Barbara B; Faias, Sandra S; Veigas, Bruno B; Pereira, Lucília Pebre LP; Albuquerque, Cristina C; Maio, Rui R; Cravo, Marília M; Fernandes, Alexandra R AR; Baptista, Pedro Viana PV

Publication Date: 2023-04-25

Variant appearance in text: KRAS: G12V

PubMed Link: 37097304

Variant Present in the following documents:

• Main text
• 216_2023_Article_4696.pdf

View BVdb publication page

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Genomic profiling of idiopathic peri-hilar cholangiocarcinoma reveals new targets and mutational pathways.

Scientific Reports

Quinn, Leonard M LM; Haldenby, Sam S; Antzcak, Philip P; Fowler, Anna A; Bullock, Katie K; Kenny, John J; Gilbert, Timothy T; Andrews, Timothy T; Diaz-Nieto, Rafael R; Fenwick, Stephen S; Jones, Robert R; Costello-Goldring, Eithne E; Poston, Graeme G; Greenhalf, William W; Palmer, Daniel D; Malik, Hassan H; Goldring, Chris C

Publication Date: 2023-04-24

Variant appearance in text: KRAS: Gly12Val

PubMed Link: 37095160

Variant Present in the following documents:

• Main text

View BVdb publication page

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Durable Response after Repeat Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in a Patient with Extensive Mucinous Adenocarcinoma of the Appendix.

Diseases (Basel, Switzerland)

Kaakour, Dalia D; Ward, Garrett G; Senthil, Maheswari M; Dayyani, Farshid F

Publication Date: 2023-04-06

Variant appearance in text: KRAS: G12V

PubMed Link: 37092442

Variant Present in the following documents:

• Main text
• diseases-11-00060.pdf

View BVdb publication page

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Guidance for clinicians and patients with non-small cell lung cancer in the time of precision medicine.

Frontiers In Oncology

Villaruz, Liza C LC; Socinski, Mark A MA; Weiss, Jared J

Publication Date: 2023

Variant appearance in text: KRAS: G12V

PubMed Link: 37077826

Variant Present in the following documents:

• Main text
• fonc-13-1124167.pdf

View BVdb publication page

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Combination CDC-like kinase inhibition (CLK)/Dual-specificity tyrosine-regulated kinase (DYRK) and taxane therapy in CTNNB1 -mutated endometrial cancer.

Biorxiv : The Preprint Server For Biology

Corr, Bradley R BR; Moroney, Marisa R MR; Woodruff, Elizabeth E; Watson, Zachary L ZL; Jordan, Kimberly R KR; Danhorn, Thomas T; Bailey, Courtney C; Wolsky, Rebecca J RJ; Bitler, Benjamin G BG

Publication Date: 2023-04-06

Variant appearance in text: KRAS: G12V

PubMed Link: 37066339

Variant Present in the following documents:

• media-2.xlsx, sheet 1

View BVdb publication page

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Somatic and germline aberrations in homologous recombination repair genes in Chinese prostate cancer patients.

Frontiers In Oncology

Liu, Yixiao Y; Jin, Bo B; Shen, Cheng C; Gao, Xianshu X; Qi, Xin X; Ma, Mingwei M; Li, Hongzhen H; Hao, Han H; Tang, Qi Q; Yang, Kaiwei K; Mi, Yue Y; Guan, Jie J; Feng, Xuero X; He, Zhisong Z; Li, Haixia H; Yu, Wei W

Publication Date: 2023

Variant appearance in text: KRAS: 35G>T; G12V

PubMed Link: 37064136

Variant Present in the following documents:

• Table_1.xlsx, sheet 1

View BVdb publication page

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Adoptive neoantigen-reactive T cell therapy: improvement strategies and current clinical researches.

Biomarker Research

Huang, Ruichen R; Zhao, Bi B; Hu, Shi S; Zhang, Qian Q; Su, Xiaoping X; Zhang, Wei W

Publication Date: 2023-04-17

Variant appearance in text: KRAS: G12V

PubMed Link: 37062844

Variant Present in the following documents:

• Main text
• 40364_2023_Article_478.pdf

View BVdb publication page

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Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.

Nature

Abbosh, Christopher C; Frankell, Alexander M AM; Harrison, Thomas T; Kisistok, Judit J; Garnett, Aaron A; Johnson, Laura L; Veeriah, Selvaraju S; Moreau, Mike M; Chesh, Adrian A; Chaunzwa, Tafadzwa L TL; Weiss, Jakob J; Schroeder, Morgan R MR; Ward, Sophia S; Grigoriadis, Kristiana K; Shahpurwalla, Aamir A; Litchfield, Kevin K; Puttick, Clare C; Biswas, Dhruva D; Karasaki, Takahiro T; Black, James R M JRM; Martínez-Ruiz, Carlos C; Bakir, Maise Al MA; Pich, Oriol O; Watkins, Thomas B K TBK; Lim, Emilia L EL; Huebner, Ariana A; Moore, David A DA; Godin-Heymann, Nadia N; L'Hernault, Anne A; Bye, Hannah H; Odell, Aaron A; Roberts, Paula P; Gomes, Fabio F; Patel, Akshay J AJ; Manzano, Elizabeth E; Hiley, Crispin T CT; Carey, Nicolas N; Riley, Joan J; Cook, Daniel E DE; Hodgson, Darren D; Stetson, Daniel D; Barrett, J Carl JC; Kortlever, Roderik M RM; Evan, Gerard I GI; Hackshaw, Allan A; Daber, Robert D RD; Shaw, Jacqui A JA; Aerts, Hugo J W L HJWL; Licon, Abel A; Stahl, Josh J; Jamal-Hanjani, Mariam M; , ; Birkbak, Nicolai J NJ; McGranahan, Nicholas N; Swanton, Charles C

Publication Date: 2023-04-13

Variant appearance in text: KRAS: G12V

PubMed Link: 37055640

Variant Present in the following documents:

• EMS176197-supplement-Supplementary_Table_1.xlsx, sheet 18

View BVdb publication page

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Molecular profiling of colorectal cancer in a genetically admixed Hispanic population.

Cancer Medicine

Montes-Rodríguez, Ingrid M IM; Centeno-Girona, Hilmaris H; Rivera-Lynch, Camila C; Rivera, Noridza N; Cruz-Correa, Marcia M

Publication Date: 2023-04-11

Variant appearance in text: KRAS: G12V

PubMed Link: 37039257

Variant Present in the following documents:

• Main text
• CAM4-12-11686.pdf

View BVdb publication page

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Genomic landscape and clinical features of rare subtypes of pancreatic cancer: analysis with the national database of Japan.

Journal Of Gastroenterology

Sakakida, Tomoki T; Ishikawa, Takeshi T; Doi, Toshifumi T; Morita, Ryuichi R; Kataoka, Seita S; Miyake, Hayato H; Yamaguchi, Kanji K; Moriguchi, Michihisa M; Sogame, Yoshio Y; Yasuda, Hiroaki H; Iwasaku, Masahiro M; Konishi, Hideyuki H; Takayama, Koichi K; Itoh, Yoshito Y

Publication Date: 2023-04-07

Variant appearance in text: KRAS: G12V

PubMed Link: 37029223

Variant Present in the following documents:

• Main text
• 535_2023_Article_1986.pdf

View BVdb publication page

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Design, Synthesis, In Vitro and In Vivo Characterization of CDC42 GTPase Interaction Inhibitors for the Treatment of Cancer.

Journal Of Medicinal Chemistry

Brindani, Nicoletta N; Vuong, Linh M LM; Acquistapace, Isabella Maria IM; La Serra, Maria Antonietta MA; Ortega, José Antonio JA; Veronesi, Marina M; Bertozzi, Sine Mandrup SM; Summa, Maria M; Girotto, Stefania S; Bertorelli, Rosalia R; Armirotti, Andrea A; Ganesan, Anand K AK; De Vivo, Marco M

Publication Date: 2023-04-07

Variant appearance in text: KRAS: Gly12Val

PubMed Link: 37026468

Variant Present in the following documents:

• Main text
• jm3c00276.pdf

View BVdb publication page

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: KRAS: G12V

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 4
• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 2
• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3

View BVdb publication page

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Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer

Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J

Publication Date: 2023-03-31

Variant appearance in text: KRAS: Gly12Val

PubMed Link: 37004022

Variant Present in the following documents:

• Main text
• 12885_2023_Article_10674.pdf

View BVdb publication page

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Deep genomic characterization highlights complexities and prognostic markers of pediatric acute myeloid leukemia.

Communications Biology

Cheng, Chi-Keung CK; Yung, Yuk-Lin YL; Chan, Hoi-Yun HY; Leung, Kam-Tong KT; Chan, Kathy Y Y KYY; Leung, Alex W K AWK; Cheng, Frankie W T FWT; Li, Chi-Kong CK; Wan, Thomas S K TSK; Luo, Xi X; Pitts, Herbert-Augustus HA; Cheung, Joyce S JS; Chan, Natalie P H NPH; Ng, Margaret H L MHL

Publication Date: 2023-03-31

Variant appearance in text: KRAS: 35G>T; G12V; rs121913529

PubMed Link: 37002311

Variant Present in the following documents:

• 42003_2023_4732_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes.

Nature Communications

Li, Lingling L; Jiang, Dongxian D; Liu, Hui H; Guo, Chunmei C; Zhao, Rui R; Zhang, Qiao Q; Xu, Chen C; Qin, Zhaoyu Z; Feng, Jinwen J; Liu, Yang Y; Wang, Haixing H; Chen, Weijie W; Zhang, Xue X; Li, Bin B; Bai, Lin L; Tian, Sha S; Tan, Subei S; Yu, Zixiang Z; Chen, Lingli L; Huang, Jie J; Zhao, Jian-Yuan JY; Hou, Yingyong Y; Ding, Chen C

Publication Date: 2023-03-29

Variant appearance in text: KRAS: G12V; rs121913529

PubMed Link: 36991000

Variant Present in the following documents:

• 41467_2023_37221_MOESM5_ESM.xlsx, sheet 3

View BVdb publication page

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The Use of Liquid Biopsy in the Molecular Analysis of Plasma Compared to the Tumour Tissue from a Patient with Brain Metastasis: A Case Report.

Medicina (Kaunas, Lithuania)

Aran, Veronica V; Zogbi, Vinicius Mansur VM; Miranda, Renan Lyra RL; Andreiuolo, Felipe F; Silva Canedo, Nathalie Henriques NH; Nazaré, Carolina Victor CV; Niemeyer Filho, Paulo P; Neto, Vivaldo Moura VM

Publication Date: 2023-02-25

Variant appearance in text: KRAS: G12V

PubMed Link: 36984460

Variant Present in the following documents:

• Main text
• medicina-59-00459.pdf

View BVdb publication page

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KRAS mutations and endometriosis burden of disease.

The Journal Of Pathology. Clinical Research

Orr, Natasha L NL; Albert, Arianne A; Liu, Yang Doris YD; Lum, Amy A; Hong, JooYoon J; Ionescu, Catalina L CL; Senz, Janine J; Nazeran, Tayyebeh M TM; Lee, Anna F AF; Noga, Heather H; Lawrenson, Kate K; Allaire, Catherine C; Williams, Christina C; Bedaiwy, Mohamed A MA; Anglesio, Michael S MS; Yong, Paul J PJ

Publication Date: 2023-03-28

Variant appearance in text: KRAS: 35G>T; G12V

PubMed Link: 36977195

Variant Present in the following documents:

• CJP2-9-302.pdf

View BVdb publication page

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