Clinical and prognostic significance of detecting CEA, EGFR, LunX, c-met and EpCAM mRNA-positive cells in the peripheral blood, tumor-draining blood and bone marrow of non-small cell lung cancer patients.
Translational Lung Cancer Research
Rehulkova, Alona A; Chudacek, Josef J; Prokopova, Andrea A; Vidlarova, Monika M; Stranska, Jana J; Drabek, Jiri J; Potockova, Jana J; Trojanec, Radek R; Vrbkova, Jana J; Skarda, Josef J; Bohanes, Tomas T; Szkorupa, Marek M; Tolmaci, Benjamin B; Klein, Jiri J; Srovnal, Josef J; Hajduch, Marian M
RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia.
The Journal Of Clinical Investigation
Ren, Jian-Gang JG; Xing, Bowen B; Lv, Kaosheng K; O'Keefe, Rachel A RA; Wu, Mengfang M; Wang, Ruoxing R; Bauer, Kaylyn M KM; Ghazaryan, Arevik A; Burslem, George M GM; Zhang, Jing J; O'Connell, Ryan M RM; Pillai, Vinodh V; Hexner, Elizabeth O EO; Philips, Mark R MR; Tong, Wei W
Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.
Biorxiv : The Preprint Server For Biology
Ratnasinghe, Brian D BD; Haque, Neshatul N; Wagenknecht, Jessica B JB; Jensen, Davin R DR; Esparza, Guadalupe V GV; Leverence, Elise N EN; De Assuncao, Thiago Milech TM; Mathison, Angela J AJ; Lomberk, Gwen G; Smith, Brian C BC; Volkman, Brian F BF; Urrutia, Raul R; Zimmermann, Michael T MT
Analysis of Circulating Tumor DNA in Synchronous Metastatic Colorectal Cancer at Diagnosis Predicts Overall Patient Survival.
International Journal Of Molecular Sciences
Sayagués, José María JM; Montero, Juan Carlos JC; Jiménez-Pérez, Andrea A; Del Carmen, Sofía S; Rodríguez, Marta M; Vidal Tocino, Rosario R; Montero, Enrique E; Sanz, Julia J; Abad, Mar M
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Nature
Abbosh, Christopher C; Frankell, Alexander M AM; Harrison, Thomas T; Kisistok, Judit J; Garnett, Aaron A; Johnson, Laura L; Veeriah, Selvaraju S; Moreau, Mike M; Chesh, Adrian A; Chaunzwa, Tafadzwa L TL; Weiss, Jakob J; Schroeder, Morgan R MR; Ward, Sophia S; Grigoriadis, Kristiana K; Shahpurwalla, Aamir A; Litchfield, Kevin K; Puttick, Clare C; Biswas, Dhruva D; Karasaki, Takahiro T; Black, James R M JRM; Martínez-Ruiz, Carlos C; Bakir, Maise Al MA; Pich, Oriol O; Watkins, Thomas B K TBK; Lim, Emilia L EL; Huebner, Ariana A; Moore, David A DA; Godin-Heymann, Nadia N; L'Hernault, Anne A; Bye, Hannah H; Odell, Aaron A; Roberts, Paula P; Gomes, Fabio F; Patel, Akshay J AJ; Manzano, Elizabeth E; Hiley, Crispin T CT; Carey, Nicolas N; Riley, Joan J; Cook, Daniel E DE; Hodgson, Darren D; Stetson, Daniel D; Barrett, J Carl JC; Kortlever, Roderik M RM; Evan, Gerard I GI; Hackshaw, Allan A; Daber, Robert D RD; Shaw, Jacqui A JA; Aerts, Hugo J W L HJWL; Licon, Abel A; Stahl, Josh J; Jamal-Hanjani, Mariam M; , ; Birkbak, Nicolai J NJ; McGranahan, Nicholas N; Swanton, Charles C
Pretreatment Plasma Circulating Tumor DNA RAS/BRAF Mutational Status in Refractory Metastatic Colorectal Cancer Patients Who Are Candidates for Anti-EGFR Rechallenge Therapy: A Pooled Analysis of the CAVE and VELO Clinical Trials.
Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Deep genomic characterization highlights complexities and prognostic markers of pediatric acute myeloid leukemia.
Communications Biology
Cheng, Chi-Keung CK; Yung, Yuk-Lin YL; Chan, Hoi-Yun HY; Leung, Kam-Tong KT; Chan, Kathy Y Y KYY; Leung, Alex W K AWK; Cheng, Frankie W T FWT; Li, Chi-Kong CK; Wan, Thomas S K TSK; Luo, Xi X; Pitts, Herbert-Augustus HA; Cheung, Joyce S JS; Chan, Natalie P H NPH; Ng, Margaret H L MHL
KRAS mutations and endometriosis burden of disease.
The Journal Of Pathology. Clinical Research
Orr, Natasha L NL; Albert, Arianne A; Liu, Yang Doris YD; Lum, Amy A; Hong, JooYoon J; Ionescu, Catalina L CL; Senz, Janine J; Nazeran, Tayyebeh M TM; Lee, Anna F AF; Noga, Heather H; Lawrenson, Kate K; Allaire, Catherine C; Williams, Christina C; Bedaiwy, Mohamed A MA; Anglesio, Michael S MS; Yong, Paul J PJ
Neuroblastoma arises in early fetal development and its evolutionary duration predicts outcome.
Nature Genetics
Körber, Verena V; Stainczyk, Sabine A SA; Kurilov, Roma R; Henrich, Kai-Oliver KO; Hero, Barbara B; Brors, Benedikt B; Westermann, Frank F; Höfer, Thomas T
Publication Date: 2023-03-27
Variant appearance in text: KRAS: G12A; rs121913529
Prognostic Mutational Signatures of NSCLC Patients treated with chemotherapy, immunotherapy and chemoimmunotherapy.
Npj Precision Oncology
Smith, Margaret R MR; Wang, Yuezhu Y; D'Agostino, Ralph R; Liu, Yin Y; Ruiz, Jimmy J; Lycan, Thomas T; Oliver, George G; Miller, Lance D LD; Topaloglu, Umit U; Pinkney, Jireh J; Abdulhaleem, Mohammed N MN; Chan, Michael D MD; Farris, Michael M; Su, Jing J; Mileham, Kathryn F KF; Xing, Fei F
Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non-small Cell Lung Cancer.
Cancer Research Communications
Frank, Malene S MS; Andersen, Christina S A CSA; Ahlborn, Lise B LB; Pallisgaard, Niels N; Bodtger, Uffe U; Gehl, Julie J
RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer.
Nature
Jbara, Amina A; Lin, Kuan-Ting KT; Stossel, Chani C; Siegfried, Zahava Z; Shqerat, Haya H; Amar-Schwartz, Adi A; Elyada, Ela E; Mogilevsky, Maxim M; Raitses-Gurevich, Maria M; Johnson, Jared L JL; Yaron, Tomer M TM; Ovadia, Ofek O; Jang, Gun Ho GH; Danan-Gotthold, Miri M; Cantley, Lewis C LC; Levanon, Erez Y EY; Gallinger, Steven S; Krainer, Adrian R AR; Golan, Talia T; Karni, Rotem R
Distribution and prognostic impact of EGFR and KRAS mutations according to histological subtype and tumor invasion status in pTis-3N0M0 lung adenocarcinoma.
Bmc Cancer
Ito, Masaoki M; Miyata, Yoshihiro Y; Kushitani, Kei K; Ueda, Daisuke D; Takeshima, Yukio Y; Okada, Morihito M
Discovery of decreased ferroptosis in male colorectal cancer patients with KRAS mutations.
Biorxiv : The Preprint Server For Biology
Yan, Hong H; Talty, Ronan R; Jain, Abhishek A; Cai, Yuping Y; Zheng, Jie J; Shen, Xinyi X; Muca, Engjel E; Paty, Philip B PB; Bosenberg, Marcus W MW; Khan, Sajid A SA; Johnson, Caroline H CH
Mimicking tumor cell heterogeneity of colorectal cancer in a patient-derived organoid-fibroblast model.
Cellular And Molecular Gastroenterology And Hepatology
Atanasova, Velina S VS; de Jesus Cardona, Crhistian C; Hejret, Václav V; Tiefenbacher, Andreas A; Mair, Theresia T; Tran, Loan L; Pfneissl, Janette J; Draganić, Kristina K; Binder, Carina C; Kabiljo, Julijan J; Clement, Janik J; Woeran, Katharina K; Neudert, Barbara B; Wohlhaupter, Sabrina S; Haase, Astrid A; Domazet, Sandra S; Hengstschläger, Markus M; Mitterhauser, Markus M; Müllauer, Leonhard L; Tichý, Boris B; Bergmann, Michael M; Schweikert, Gabriele G; Hartl, Markus M; Dolznig, Helmut H; Egger, Gerda G