KRAS c.34_35delinsTT ;(p.G12F)

Variant ID: 12-25398284-CC-AA

NM_004985.3(KRAS):c.34_35delinsTT;(p.G12F)

This variant was identified in 169 publications

View GRCh38 version.




Publications:


Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape.

Biorxiv : The Preprint Server For Biology
Ratnasinghe, Brian D BD; Haque, Neshatul N; Wagenknecht, Jessica B JB; Jensen, Davin R DR; Esparza, Guadalupe V GV; Leverence, Elise N EN; De Assuncao, Thiago Milech TM; Mathison, Angela J AJ; Lomberk, Gwen G; Smith, Brian C BC; Volkman, Brian F BF; Urrutia, Raul R; Zimmermann, Michael T MT
Publication Date: 2023-04-28

Variant appearance in text: KRAS: G12F
PubMed Link: 37207265
Variant Present in the following documents:
  • Main text
  • nihpp-2023.04.28.536249v1.pdf
View BVdb publication page



Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer
Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J
Publication Date: 2023-03-31

Variant appearance in text: KRAS: Gly12Phe
PubMed Link: 37004022
Variant Present in the following documents:
  • Main text
View BVdb publication page



An absolute approach to using whole exome DNA and RNA workflow for cancer biomarker testing.

Frontiers In Oncology
Malhotra, Richa R; Javle, Vyomesh V; Tanwar, Nishtha N; Gowda, Pooja P; Varghese, Linu L; K, Anju A; Madhusudhan, Nandhitha N; Jaiswal, Nupur N; K S, Bhargavi B; Chatterjee, Manjima M; Prabhash, Kumar K; Sreekanthreddy, Peddagangannagari P; Rishi, Kshitij D KD; Goswami, Hitesh M HM; Veldore, Vidya H VH
Publication Date: 2023

Variant appearance in text: KRAS: G12F
PubMed Link: 36994199
Variant Present in the following documents:
  • Main text
  • fonc-13-1002792.pdf
View BVdb publication page



KRAS, NRAS, BRAF, HER2 and MSI Status in a Large Consecutive Series of Colorectal Carcinomas.

International Journal Of Molecular Sciences
Martianov, Aleksandr S AS; Mitiushkina, Natalia V NV; Ershova, Anastasia N AN; Martynenko, Darya E DE; Bubnov, Mikhail G MG; Amankwah, Priscilla P; Yanus, Grigory A GA; Aleksakhina, Svetlana N SN; Tiurin, Vladislav I VI; Venina, Aigul R AR; Anuskina, Aleksandra A AA; Gorgul, Yuliy A YA; Shestakova, Anna D AD; Maidin, Mikhail A MA; Belyaev, Alexey M AM; Baboshkina, Liliya S LS; Iyevleva, Aglaya G AG; Imyanitov, Evgeny N EN
Publication Date: 2023-03-02

Variant appearance in text: KRAS: G12F
PubMed Link: 36902296
Variant Present in the following documents:
  • Main text
  • ijms-24-04868.pdf
View BVdb publication page



Novel mutant KRAS addiction signature predicts response to the combination of ERBB and MEK inhibitors in lung and pancreatic cancers.

Iscience
Tyc, Katarzyna M KM; Kazi, Aslamuzzaman A; Ranjan, Alok A; Wang, Rui R; Sebti, Said M SM
Publication Date: 2023-03-17

Variant appearance in text: KRAS: G12F
PubMed Link: 36852277
Variant Present in the following documents:
  • mmc2.xlsx, sheet 2
View BVdb publication page



Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications
Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI
Publication Date: 2023-02-08

Variant appearance in text: KRAS: 34_35delinsTT
PubMed Link: 36755027
Variant Present in the following documents:
  • 41467_2023_36328_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors.

Cell Reports. Medicine
Álvarez-Prado, Ángel F ÁF; Maas, Roeltje R RR; Soukup, Klara K; Klemm, Florian F; Kornete, Mara M; Krebs, Fanny S FS; Zoete, Vincent V; Berezowska, Sabina S; Brouland, Jean-Philippe JP; Hottinger, Andreas F AF; Daniel, Roy T RT; Hegi, Monika E ME; Joyce, Johanna A JA
Publication Date: 2023-01-17

Variant appearance in text: KRAS: G12F
PubMed Link: 36652909
Variant Present in the following documents:
  • mmc3.xlsx, sheet 31
View BVdb publication page



KRAS G12D targeted therapies for pancreatic cancer: Has the fortress been conquered?

Frontiers In Oncology
Bannoura, Sahar F SF; Khan, Husain Yar HY; Azmi, Asfar S AS
Publication Date: 2022

Variant appearance in text: KRAS: G12F
PubMed Link: 36531078
Variant Present in the following documents:
  • Main text
  • fonc-12-1013902.pdf
View BVdb publication page



Spatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients.

Cell Genomics
Wu, Hua-Jun HJ; Temko, Daniel D; Maliga, Zoltan Z; Moreira, Andre L AL; Sei, Emi E; Minussi, Darlan Conterno DC; Dean, Jamie J; Lee, Charlotte C; Xu, Qiong Q; Hochart, Guillaume G; Jacobson, Connor A CA; Yapp, Clarence C; Schapiro, Denis D; Sorger, Peter K PK; Seeley, Erin H EH; Navin, Nicholas N; Downey, Robert J RJ; Michor, Franziska F
Publication Date: 2022-08-10

Variant appearance in text: KRAS: G12F
PubMed Link: 36419822
Variant Present in the following documents:
  • NIHMS1829514-supplement-2.xlsx, sheet 1
View BVdb publication page



Up-front mutation detection in circulating tumor DNA by droplet digital PCR has added diagnostic value in lung cancer.

Translational Oncology
Visser, Esther E; de Kock, Remco R; Genet, Sylvia S; Borne, Ben van den BVD; Soud, Maggy Youssef-El MY; Belderbos, Huub H; Stege, Gerben G; de Saegher, Marleen M; 't Westeinde, Susan van SV; Broeren, Maarten M; Eduati, Federica F; Deiman, Birgit B; Scharnhorst, Volkher V
Publication Date: 2022-11-19

Variant appearance in text: KRAS: G12F
PubMed Link: 36413862
Variant Present in the following documents:
  • mmc1.pdf
View BVdb publication page



Molecular characterization of acquired resistance to KRAS G12C-EGFR inhibition in colorectal cancer.

Cancer Discovery
Yaeger, Rona R; Mezzadra, Riccardo R; Sinopoli, Jenna J; Bian, Yu Y; Marasco, Michelangelo M; Kaplun, Esther E; Gao, Yijun Y; Zhao, HuiYong H; Da Cruz Paula, Arnaud A; Zhu, Yingjie Y; Chaves Perez, Almudena A; Chadalavada, Kalyani K; Tse, Edison E; Chowdhry, Sudhir S; Bowker, Sydney S; Chang, Qing Q; Qeriqi, Besnik B; Weigelt, Britta B; Nanjangud, Gouri J GJ; Berger, Michael F MF; Der-Torossian, Hirak H; Anderes, Kenna K; Socci, Nicholas D ND; Shia, Jinru J; Riely, Gregory J GJ; Murciano-Goroff, Yonina R YR; Li, Bob T BT; Christensen, James G JG; Reis-Filho, Jorge S JS; Solit, David B DB; de Stanchina, Elisa E; Lowe, Scott W SW; Rosen, Neal N; Misale, Sandra S
Publication Date: 2022-11-10

Variant appearance in text: KRAS: G12F
PubMed Link: 36355783
Variant Present in the following documents:
  • 41.pdf
View BVdb publication page



Sotorasib: A Review in KRAS G12C Mutation-Positive Non-small Cell Lung Cancer.

Targeted Oncology
Lee, Arnold A
Publication Date: 2022-11

Variant appearance in text: KRAS: G12F
PubMed Link: 36315377
Variant Present in the following documents:
  • Main text
  • 11523_2022_Article_922.pdf
View BVdb publication page



A comparison of DNA sequencing and gene expression profiling to assist tissue of origin diagnosis in cancer of unknown primary.

The Journal Of Pathology
Posner, Atara A; Prall, Owen Wj OW; Sivakumaran, Tharani T; Etemadamoghadam, Dariush D; Thio, Niko N; Pattison, Andrew A; Balachander, Shiva S; Fisher, Krista K; Webb, Samantha S; Wood, Colin C; DeFazio, Anna A; Wilcken, Nicholas N; Gao, Bo B; Karapetis, Christos S CS; Singh, Madhu M; Collins, Ian M IM; Richardson, Gary G; Steer, Christopher C; Warren, Mark M; Karanth, Narayan N; Wright, Gavin G; Williams, Scott S; George, Joshy J; Hicks, Rodney J RJ; Boussioutas, Alex A; Gill, Anthony J AJ; Solomon, Benjamin J BJ; Xu, Huiling H; Fellowes, Andrew A; Fox, Stephen B SB; Schofield, Penelope P; Bowtell, David D; Mileshkin, Linda L; Tothill, Richard W RW
Publication Date: 2022-10-26

Variant appearance in text: KRAS: G12F
PubMed Link: 36287571
Variant Present in the following documents:
  • PATH-259-81-s011.xlsx, sheet 2
View BVdb publication page



Drugging KRAS: current perspectives and state-of-art review.

Journal Of Hematology & Oncology
Parikh, Kaushal K; Banna, Giuseppe G; Liu, Stephen V SV; Friedlaender, Alex A; Desai, Aakash A; Subbiah, Vivek V; Addeo, Alfredo A
Publication Date: 2022-10-25

Variant appearance in text: KRAS: G12F
PubMed Link: 36284306
Variant Present in the following documents:
  • Main text
  • 13045_2022_Article_1375.pdf
View BVdb publication page



EV-ADD, a database for EV-associated DNA in human liquid biopsy samples.

Journal Of Extracellular Vesicles
Tsering, Thupten T; Li, Mingyang M; Chen, Yunxi Y; Nadeau, Amélie A; Laskaris, Alexander A; Abdouh, Mohamed M; Bustamante, Prisca P; Burnier, Julia V JV
Publication Date: 2022-10

Variant appearance in text: KRAS: G12F
PubMed Link: 36271888
Variant Present in the following documents:
  • JEV2-11-e12270-s002.xlsx, sheet 1
View BVdb publication page



The mutational landscape of cancer's vulnerability to ionizing radiation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Gopal, Priyanka P; Yard, Brian D BD; Petty, Aaron A; Lal, Jessica C JC; Bera, Titas K TK; Hoang, Trung Q TQ; Buhimschi, Alexandru B AB; Abazeed, Mohamed E ME
Publication Date: 2022-10-12

Variant appearance in text: KRAS: G12F
PubMed Link: 36222846
Variant Present in the following documents:
  • ccr-22-1914_supplementary_data_3_suppds3.xlsx, sheet 1
  • ccr-22-1914_supplementary_data_2_suppds2.xlsx, sheet 1
View BVdb publication page



Utilization of cytologic cell blocks for targeted sequencing of solid tumors.

Cancer Medicine
Vormittag-Nocito, Erica E; Kumar, Ravindra R; Narayan, Kunwar Digvijay KD; Chen, Zhengjia Z; David, Odile O; Behm, Frederick F; Mohapatra, Gayatry G
Publication Date: 2022-09-20

Variant appearance in text: KRAS: G12F
PubMed Link: 36125633
Variant Present in the following documents:
  • Main text
  • CAM4-12-4042.pdf
View BVdb publication page



Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology
Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M
Publication Date: 2022

Variant appearance in text: KRAS: G12F
PubMed Link: 35936718
Variant Present in the following documents:
  • Table_4.xlsx, sheet 2
View BVdb publication page



The circulating tumor DNA (ctDNA) alteration level predicts therapeutic response in metastatic breast cancer: Novel prognostic indexes based on ctDNA.

Breast (Edinburgh, Scotland)
Liu, Binliang B; Hu, Zheyu Z; Ran, Jialu J; Xie, Ning N; Tian, Can C; Tang, Yu Y; Ouyang, Quchang Q
Publication Date: 2022-10

Variant appearance in text: KRAS: G12F
PubMed Link: 35926241
Variant Present in the following documents:
  • mmc1.xlsx, sheet 1
View BVdb publication page



Characteristics and Treatment Outcomes in Advanced-Stage Non-Small Cell Lung Cancer Patients with a KRAS G12C Mutation: A Real-World Study.

Journal Of Clinical Medicine
Illini, Oliver O; Fabikan, Hannah H; Hochmair, Maximilian Johannes MJ; Weinlinger, Christoph C; Krenbek, Dagmar D; Brcic, Luka L; Setinek, Ulrike U; Terbuch, Angelika A; Absenger, Gudrun G; Konjić, Selma S; Valipour, Arschang A
Publication Date: 2022-07-15

Variant appearance in text: KRAS: G12F
PubMed Link: 35887862
Variant Present in the following documents:
  • jcm-11-04098.pdf
View BVdb publication page



Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer.

Nature Communications
Bartolacci, Caterina C; Andreani, Cristina C; Vale, Gonçalo G; Berto, Stefano S; Melegari, Margherita M; Crouch, Anna Colleen AC; Baluya, Dodge L DL; Kemble, George G; Hodges, Kurt K; Starrett, Jacqueline J; Politi, Katerina K; Starnes, Sandra L SL; Lorenzini, Daniele D; Raso, Maria Gabriela MG; Solis Soto, Luisa M LM; Behrens, Carmen C; Kadara, Humam H; Gao, Boning B; Wistuba, Ignacio I II; Minna, John D JD; McDonald, Jeffrey G JG; Scaglioni, Pier Paolo PP
Publication Date: 2022-07-26

Variant appearance in text: KRAS: G12F
PubMed Link: 35882862
Variant Present in the following documents:
  • 41467_2022_31963_MOESM11_ESM.xlsx, sheet 2
View BVdb publication page



Targeting KRAS G12C-Mutated Advanced Colorectal Cancer: Research and Clinical Developments.

Oncotargets And Therapy
Ji, Jingran J; Wang, Chongkai C; Fakih, Marwan M
Publication Date: 2022

Variant appearance in text: KRAS: G12F
PubMed Link: 35837349
Variant Present in the following documents:
  • Main text
  • ott-15-747.pdf
View BVdb publication page



The treatment of advanced non-small cell lung cancer harboring KRAS mutation: a new class of drugs for an old target-a narrative review.

Translational Lung Cancer Research
Spagnuolo, Alessia A; Maione, Paolo P; Gridelli, Cesare C
Publication Date: 2022-06

Variant appearance in text: KRAS: G12F
PubMed Link: 35832439
Variant Present in the following documents:
  • tlcr-11-06-1199.pdf
View BVdb publication page



Surgical Treatment of Intraductal Papillary Neoplasm of the Bile Duct: A Report of Two Cases and Review of the Literature.

Frontiers In Oncology
Li, Binjie B; Liu, Zhiqiang Z; Meng, Zhuo Z; Li, Mingyang M; Tian, Weijun W; Liu, Quanyan Q
Publication Date: 2022

Variant appearance in text: KRAS: G12F
PubMed Link: 35814451
Variant Present in the following documents:
  • Main text
  • fonc-12-916457.pdf
View BVdb publication page



Whole-Exome Sequencing Could Distinguish Primary Pulmonary Squamous Cell Carcinoma From Lung Metastases in Individuals With Cervical Squamous Cell Carcinoma.

Pathology Oncology Research : Por
Li, Lihong L; Song, Qianqian Q; Cao, Dandan D; Jiao, Yuchen Y; Yuan, Guangwen G; Song, Yan Y
Publication Date: 2022

Variant appearance in text: KRAS: G12f
PubMed Link: 35645619
Variant Present in the following documents:
  • DataSheet1.xlsx, sheet 3
  • DataSheet1.xlsx, sheet 2
View BVdb publication page



Analytical validation and initial clinical testing of quantitative microscopic evaluation for PD-L1 and HLA I expression on circulating tumor cells from patients with non-small cell lung cancer.

Biomarker Research
Schehr, Jennifer L JL; Sethakorn, Nan N; Schultz, Zachery D ZD; Hernandez, Camila I CI; Bade, Rory M RM; Eyzaguirre, Diego D; Singh, Anupama A; Niles, David J DJ; Henderson, Leslie L; Warrick, Jay W JW; Berry, Scott M SM; Sundling, Kaitlin E KE; Beebe, David J DJ; Leal, Ticiana A TA; Lang, Joshua M JM
Publication Date: 2022-04-25

Variant appearance in text: KRAS: G12F
PubMed Link: 35468853
Variant Present in the following documents:
  • 40364_2022_370_MOESM1_ESM.pdf
View BVdb publication page



KRAS Mutation in Rare Tumors: A Landscape Analysis of 3453 Chinese Patients.

Frontiers In Molecular Biosciences
Wang, Shuhang S; Li, Qin Q; Ma, Peiwen P; Fang, Yuan Y; Yu, Yue Y; Jiang, Ning N; Miao, Huilei H; Tang, Qiyu Q; Yang, Yuqi Y; Xing, Shujun S; Chen, Rongrong R; Yi, Xin X; Li, Ning N
Publication Date: 2022

Variant appearance in text: KRAS: G12F
PubMed Link: 35359599
Variant Present in the following documents:
  • Main text
View BVdb publication page



Response prediction and risk stratification of patients with rectal cancer after neoadjuvant therapy through an analysis of circulating tumour DNA.

Ebiomedicine
Liu, Wenyang W; Li, Yifei Y; Tang, Yuan Y; Song, Qianqian Q; Wang, Jingjing J; Li, Ning N; Chen, Silin S; Shi, Jinming J; Wang, Shulian S; Li, Yexiong Y; Jiao, Yuchen Y; Zeng, Yixin Y; Jin, Jing J
Publication Date: 2022-04

Variant appearance in text: KRAS: G12f
PubMed Link: 35306340
Variant Present in the following documents:
  • mmc3.xlsx, sheet 2
View BVdb publication page



Targeting KRAS Mutant in Non-Small Cell Lung Cancer: Novel Insights Into Therapeutic Strategies.

Frontiers In Oncology
Désage, Anne-Laure AL; Léonce, Camille C; Swalduz, Aurélie A; Ortiz-Cuaran, Sandra S
Publication Date: 2022

Variant appearance in text: KRAS: G12F
PubMed Link: 35251972
Variant Present in the following documents:
  • Main text
  • fonc-12-796832.pdf
View BVdb publication page



Concomitant KRAS mutations attenuate sensitivity of non-small cell lung cancer cells to KRAS G12C inhibition.

Scientific Reports
Vaclova, Tereza T; Chakraborty, Atanu A; Sherwood, James J; Ross, Sarah S; Carroll, Danielle D; Barrett, J Carl JC; Downward, Julian J; de Bruin, Elza C EC
Publication Date: 2022-02-17

Variant appearance in text: KRAS: G12F
PubMed Link: 35177674
Variant Present in the following documents:
  • Main text
  • 41598_2022_Article_6369.pdf
  • 41598_2022_6369_MOESM1_ESM.pdf
View BVdb publication page



Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics
Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y
Publication Date: 2022-01-15

Variant appearance in text: KRAS: 34_35delinsTT
PubMed Link: 35031014
Variant Present in the following documents:
  • 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics
Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y
Publication Date: 2022-01-15

Variant appearance in text: KRAS: 34_35delinsTT
PubMed Link: 35031014
Variant Present in the following documents:
  • 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Targeting KRAS in NSCLC: Old Failures and New Options for "Non-G12c" Patients.

Cancers
Jacobs, Francesca F; Cani, Massimiliano M; Malapelle, Umberto U; Novello, Silvia S; Napoli, Valerio Maria VM; Bironzo, Paolo P
Publication Date: 2021-12-16

Variant appearance in text: KRAS: G12F
PubMed Link: 34944952
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeting KRAS in NSCLC: Old Failures and New Options for "Non-G12c" Patients.

Cancers
Jacobs, Francesca F; Cani, Massimiliano M; Malapelle, Umberto U; Novello, Silvia S; Napoli, Valerio Maria VM; Bironzo, Paolo P
Publication Date: 2021-12-16

Variant appearance in text: KRAS: G12F
PubMed Link: 34944952
Variant Present in the following documents:
  • Main text
View BVdb publication page



Comparison of Two Blood-Based Genotyping Tests to Investigate the KRAS G12C Mutation in Patients with Non-Small-Cell Lung Cancer at Failure of First-Line Treatments.

Diagnostics (Basel, Switzerland)
Nicolazzo, Chiara C; Gelibter, Alain A; Bottillo, Irene I; Belardinilli, Francesca F; Pisegna, Simona S; De Renzi, Gianluigi G; Marinelli, Daniele D; Grammatico, Paola P; Cortesi, Enrico E; Giannini, Giuseppe G; Gazzaniga, Paola P
Publication Date: 2021-11-25

Variant appearance in text: KRAS: G12F
PubMed Link: 34943432
Variant Present in the following documents:
  • Main text
View BVdb publication page



Local tumor microbial signatures and response to checkpoint blockade in non-small cell lung cancer.

Oncoimmunology
Boesch, Maximilian M; Baty, Florent F; Albrich, Werner C WC; Flatz, Lukas L; Rodriguez, Regulo R; Rothschild, Sacha I SI; Joerger, Markus M; Früh, Martin M; Brutsche, Martin H MH
Publication Date: 2021

Variant appearance in text: KRAS: G12F
PubMed Link: 34912592
Variant Present in the following documents:
  • Main text
  • KONI_10_1988403.pdf
View BVdb publication page



Local tumor microbial signatures and response to checkpoint blockade in non-small cell lung cancer.

Oncoimmunology
Boesch, Maximilian M; Baty, Florent F; Albrich, Werner C WC; Flatz, Lukas L; Rodriguez, Regulo R; Rothschild, Sacha I SI; Joerger, Markus M; Früh, Martin M; Brutsche, Martin H MH
Publication Date: 2021

Variant appearance in text: KRAS: G12F
PubMed Link: 34912592
Variant Present in the following documents:
  • Main text
  • KONI_10_1988403.pdf
View BVdb publication page



Targeting Oncogenic KRAS in Non-Small-Cell Lung Cancer.

Cancers
Sunaga, Noriaki N; Miura, Yosuke Y; Kasahara, Norimitsu N; Sakurai, Reiko R
Publication Date: 2021-11-26

Variant appearance in text: KRAS: G12F
PubMed Link: 34885068
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeting Oncogenic KRAS in Non-Small-Cell Lung Cancer.

Cancers
Sunaga, Noriaki N; Miura, Yosuke Y; Kasahara, Norimitsu N; Sakurai, Reiko R
Publication Date: 2021-11-26

Variant appearance in text: KRAS: G12F
PubMed Link: 34885068
Variant Present in the following documents:
  • Main text
View BVdb publication page



STK11/LKB1 Modulation of the Immune Response in Lung Cancer: From Biology to Therapeutic Impact.

Cells
Pons-Tostivint, Elvire E; Lugat, Alexandre A; Fontenau, Jean-François JF; Denis, Marc Guillaume MG; Bennouna, Jaafar J
Publication Date: 2021-11-11

Variant appearance in text: KRAS: G12F
PubMed Link: 34831355
Variant Present in the following documents:
  • Main text
  • cells-10-03129.pdf
View BVdb publication page



Evaluation of KRAS Concomitant Mutations in Advanced Lung Adenocarcinoma Patients.

Medicina (Kaunas, Lithuania)
Aran, Veronica V; Zalis, Mariano M; Montella, Tatiane T; de Sousa, Carlos Augusto Moreira CAM; Ferrari, Bruno L BL; Gil Ferreira, Carlos C
Publication Date: 2021-09-29

Variant appearance in text: KRAS: G12F
PubMed Link: 34684076
Variant Present in the following documents:
  • Main text
  • medicina-57-01039.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: N/A
PubMed Link: 34630336
Variant Present in the following documents:
View BVdb publication page



CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer.

Scientific Reports
Gutiontov, Stanley I SI; Turchan, William Tyler WT; Spurr, Liam F LF; Rouhani, Sherin J SJ; Chervin, Carolina Soto CS; Steinhardt, George G; Lager, Angela M AM; Wanjari, Pankhuri P; Malik, Renuka R; Connell, Philip P PP; Chmura, Steven J SJ; Juloori, Aditya A; Hoffman, Philip C PC; Ferguson, Mark K MK; Donington, Jessica S JS; Patel, Jyoti D JD; Vokes, Everett E EE; Weichselbaum, Ralph R RR; Bestvina, Christine M CM; Segal, Jeremy P JP; Pitroda, Sean P SP
Publication Date: 2021-10-08

Variant appearance in text: KRAS: 34_35delinsTT
PubMed Link: 34625620
Variant Present in the following documents:
  • 41598_2021_99524_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Outcomes of Patients With Advanced NSCLC From the Intergroupe Francophone de Cancérologie Thoracique Biomarkers France Study by KRAS Mutation Subtypes.

Jto Clinical And Research Reports
Ruppert, Anne-Marie AM; Beau-Faller, Michèle M; Debieuvre, Didier D; Ouafik, L'Houcine L; Westeel, Virginie V; Rouquette, Isabelle I; Mazières, Julien J; Bringuier, Pierre-Paul PP; Monnet, Isabelle I; Escande, Fabienne F; Ricordel, Charles C; Merlio, Jean-Philippe JP; Janicot, Henri H; Lemoine, Antoinette A; Foucher, Pascal P; Poudenx, Michel M; Morin, Franck F; Langlais, Alexandra A; Souquet, Pierre-Jean PJ; Barlesi, Fabrice F; Wislez, Marie M
Publication Date: 2020-09

Variant appearance in text: KRAS: G12F
PubMed Link: 34589947
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High SHP2 expression determines the efficacy of PD-1/PD-L1 inhibitors in advanced KRAS mutant non-small cell lung cancer.

Thoracic Cancer
Feng, Hui-Bo HB; Chen, Yu Y; Xie, Zhi Z; Jiang, Jie J; Zhong, Yu-Min YM; Guo, Wei-Bang WB; Yan, Wen-Qing WQ; Lv, Zhi-Yi ZY; Lu, Dan-Xia DX; Liang, Hong-Ling HL; Xu, Fang-Ping FP; Yang, Jin-Ji JJ; Yang, Xue-Ning XN; Zhou, Qing Q; Zhang, Dong-Kun DK; Zhang, Zhou Z; Chuai, Shao-Kun SK; Zhang, Heng-Hui HH; Wu, Yi-Long YL; Zhang, Xu-Chao XC
Publication Date: 2021-10

Variant appearance in text: KRAS: G12F
PubMed Link: 34490728
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  • TCA-12-2564.pdf
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High SHP2 expression determines the efficacy of PD-1/PD-L1 inhibitors in advanced KRAS mutant non-small cell lung cancer.

Thoracic Cancer
Feng, Hui-Bo HB; Chen, Yu Y; Xie, Zhi Z; Jiang, Jie J; Zhong, Yu-Min YM; Guo, Wei-Bang WB; Yan, Wen-Qing WQ; Lv, Zhi-Yi ZY; Lu, Dan-Xia DX; Liang, Hong-Ling HL; Xu, Fang-Ping FP; Yang, Jin-Ji JJ; Yang, Xue-Ning XN; Zhou, Qing Q; Zhang, Dong-Kun DK; Zhang, Zhou Z; Chuai, Shao-Kun SK; Zhang, Heng-Hui HH; Wu, Yi-Long YL; Zhang, Xu-Chao XC
Publication Date: 2021-10

Variant appearance in text: KRAS: G12F
PubMed Link: 34490728
Variant Present in the following documents:
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  • TCA-12-2564.pdf
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Clinical Utility of Liquid Biopsy-Based Actionable Mutations Detected via ddPCR.

Biomedicines
Palacín-Aliana, Irina I; García-Romero, Noemí N; Asensi-Puig, Adrià A; Carrión-Navarro, Josefa J; González-Rumayor, Víctor V; Ayuso-Sacido, Ángel Á
Publication Date: 2021-07-28

Variant appearance in text: KRAS: G12F
PubMed Link: 34440110
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Orthogonal MET analysis in a population-representative stage II-III colon cancer cohort: prognostic and potential therapeutic implications.

Molecular Oncology
Craig, Stephanie G SG; Mende, Svenja S; Humphries, Matthew P MP; Bingham, Victoria V; Viratham Pulsawatdi, Amélie A; Loughrey, Maurice B MB; Coleman, Helen G HG; McQuaid, Stephen S; Wilson, Richard H RH; Van Schaeybroeck, Sandra S; James, Jacqueline A JA; Salto-Tellez, Manuel M
Publication Date: 2021-12

Variant appearance in text: KRAS: G12F
PubMed Link: 34428346
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  • MOL2-15-3317.pdf
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Orthogonal MET analysis in a population-representative stage II-III colon cancer cohort: prognostic and potential therapeutic implications.

Molecular Oncology
Craig, Stephanie G SG; Mende, Svenja S; Humphries, Matthew P MP; Bingham, Victoria V; Viratham Pulsawatdi, Amélie A; Loughrey, Maurice B MB; Coleman, Helen G HG; McQuaid, Stephen S; Wilson, Richard H RH; Van Schaeybroeck, Sandra S; James, Jacqueline A JA; Salto-Tellez, Manuel M
Publication Date: 2021-12

Variant appearance in text: KRAS: G12F
PubMed Link: 34428346
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  • MOL2-15-3317.pdf
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Genomic alterations and possible druggable mutations in carcinoma of unknown primary (CUP).

Scientific Reports
Es, Hamidreza Aboulkheyr HA; Mahdizadeh, Hamid H; Asl, Amir Abbas Hedayati AAH; Totonchi, Mehdi M
Publication Date: 2021-07-23

Variant appearance in text: KRAS: G12F
PubMed Link: 34302033
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  • 41598_2021_Article_94678.pdf
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The landscape of driver mutations in cutaneous squamous cell carcinoma.

Npj Genomic Medicine
Chang, Darwin D; Shain, A Hunter AH
Publication Date: 2021-07-16

Variant appearance in text: KRAS: G12F
PubMed Link: 34272401
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Notch1 Deficiency Induces Tumor Cell Accumulation Inside the Bronchiolar Lumen and Increases TAZ Expression in an Autochthonous Kras LSL-G12V Driven Lung Cancer Mouse Model.

Pathology Oncology Research : Por
Meder, Lydia L; Florin, Alexandra A; Ozretić, Luka L; Nill, Marieke M; Koker, Mirjam M; Meemboor, Sonja S; Radtke, Freddy F; Diehl, Linda L; Ullrich, Roland T RT; Odenthal, Margarete M; Büttner, Reinhard R; Heukamp, Lukas C LC
Publication Date: 2021

Variant appearance in text: KRAS: G12F
PubMed Link: 34257546
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