RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia.
The Journal Of Clinical Investigation
Ren, Jian-Gang JG; Xing, Bowen B; Lv, Kaosheng K; O'Keefe, Rachel A RA; Wu, Mengfang M; Wang, Ruoxing R; Bauer, Kaylyn M KM; Ghazaryan, Arevik A; Burslem, George M GM; Zhang, Jing J; O'Connell, Ryan M RM; Pillai, Vinodh V; Hexner, Elizabeth O EO; Philips, Mark R MR; Tong, Wei W
Fibroblast Growth Factor 11 Enables Tumor Cell Immune Escape by Promoting T Cell Exhaustion and Predicts Poor Prognosis in Patients with Lung Adenocarcinoma.
Challenges and Limitations of Endocrine Toxicity Evaluation in Non-Small Cell Lung Cancer Patients Treated with Immunotherapy-Retrospective Study from a Tertiary-Level Hospital in Romania.
Evolution of age-related mutation-driven clonal haematopoiesis over 20 years is associated with metabolic dysfunction in obesity.
Ebiomedicine
Andersson-Assarsson, Johanna C JC; van Deuren, Rosanne C RC; Kristensson, Felipe M FM; Steehouwer, Marloes M; Sjöholm, Kajsa K; Svensson, Per-Arne PA; Pieterse, Marc M; Gilissen, Christian C; Taube, Magdalena M; Jacobson, Peter P; Perkins, Rosie R; Brunner, Han G HG; Netea, Mihai G MG; Peltonen, Markku M; Carlsson, Björn B; Hoischen, Alexander A; Carlsson, Lena M S LMS
The efficacy of immune checkpoint inhibitors in biliary tract cancer with KRAS mutation.
Therapeutic Advances In Gastroenterology
Jeong, Sun Young SY; Hong, Jung Yong JY; Park, Joon Oh JO; Park, Young Suk YS; Lim, Ho Yeong HY; Jang, Jae Yeon JY; Jeon, Youngkyung Y; Kim, Seung Tae ST
Smaller panel, similar results: genomic profiling and molecularly informed therapy in pancreatic cancer.
Esmo Open
Reissig, T M TM; Tzianopoulos, I I; Liffers, S-T ST; Rosery, V K VK; Guyot, M M; Ting, S S; Wiesweg, M M; Kasper, S S; Meister, P P; Herold, T T; Schmidt, H H HH; Schumacher, B B; Albers, D D; Markus, P P; Treckmann, J J; Schuler, M M; Schildhaus, H-U HU; Siveke, J T JT
The immunopeptidome landscape associated with T cell infiltration, inflammation and immune editing in lung cancer.
Nature Cancer
Kraemer, Anne I AI; Chong, Chloe C; Huber, Florian F; Pak, HuiSong H; Stevenson, Brian J BJ; Müller, Markus M; Michaux, Justine J; Altimiras, Emma Ricart ER; Rusakiewicz, Sylvie S; Simó-Riudalbas, Laia L; Planet, Evarist E; Wiznerowicz, Maciej M; Dagher, Julien J; Trono, Didier D; Coukos, George G; Tissot, Stephanie S; Bassani-Sternberg, Michal M
Reactive fragments targeting carboxylate residues employing direct to biology, high-throughput chemistry.
Rsc Medicinal Chemistry
Thomas, Ross P RP; Grant, Emma K EK; Dickinson, Eleanor R ER; Zappacosta, Francesca F; Edwards, Lee J LJ; Hann, Michael M MM; House, David D; Tomkinson, Nicholas C O NCO; Bush, Jacob T JT
DREAMS: deep read-level error model for sequencing data applied to low-frequency variant calling and circulating tumor DNA detection.
Genome Biology
Christensen, Mikkel H MH; Drue, Simon O SO; Rasmussen, Mads H MH; Frydendahl, Amanda A; Lyskjær, Iben I; Demuth, Christina C; Nors, Jesper J; Gotschalck, Kåre A KA; Iversen, Lene H LH; Andersen, Claus L CL; Pedersen, Jakob Skou JS
Dynamics of Sequence and Structural Cell-Free DNA Landscapes in Small-Cell Lung Cancer.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Sivapalan, Lavanya L; Iams, Wade T WT; Belcaid, Zineb Z; Scott, Susan C SC; Niknafs, Noushin N; Balan, Archana A; White, James R JR; Kopparapu, Prasad P; Cann, Christopher C; Landon, Blair V BV; Pereira, Gavin G; Velculescu, Victor E VE; Hann, Christine L CL; Lovly, Christine M CM; Anagnostou, Valsamo V
A Rapid, Functional sgRNA Screening Method for Generating Murine RET and NTRK1 Fusion Oncogenes.
Biorxiv : The Preprint Server For Biology
Schubert, Laura L; Le, Anh T AT; Hinz, Trista K TK; Navarro, Andre A; Nelson-Taylor, Sarah K SK; Nemenoff, Raphael A RA; Heasley, Lynn E LE; Doebele, Robert C RC
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.
Nature
Abbosh, Christopher C; Frankell, Alexander M AM; Harrison, Thomas T; Kisistok, Judit J; Garnett, Aaron A; Johnson, Laura L; Veeriah, Selvaraju S; Moreau, Mike M; Chesh, Adrian A; Chaunzwa, Tafadzwa L TL; Weiss, Jakob J; Schroeder, Morgan R MR; Ward, Sophia S; Grigoriadis, Kristiana K; Shahpurwalla, Aamir A; Litchfield, Kevin K; Puttick, Clare C; Biswas, Dhruva D; Karasaki, Takahiro T; Black, James R M JRM; Martínez-Ruiz, Carlos C; Bakir, Maise Al MA; Pich, Oriol O; Watkins, Thomas B K TBK; Lim, Emilia L EL; Huebner, Ariana A; Moore, David A DA; Godin-Heymann, Nadia N; L'Hernault, Anne A; Bye, Hannah H; Odell, Aaron A; Roberts, Paula P; Gomes, Fabio F; Patel, Akshay J AJ; Manzano, Elizabeth E; Hiley, Crispin T CT; Carey, Nicolas N; Riley, Joan J; Cook, Daniel E DE; Hodgson, Darren D; Stetson, Daniel D; Barrett, J Carl JC; Kortlever, Roderik M RM; Evan, Gerard I GI; Hackshaw, Allan A; Daber, Robert D RD; Shaw, Jacqui A JA; Aerts, Hugo J W L HJWL; Licon, Abel A; Stahl, Josh J; Jamal-Hanjani, Mariam M; , ; Birkbak, Nicolai J NJ; McGranahan, Nicholas N; Swanton, Charles C
MYC activation impairs cell-intrinsic IFNγ signaling and confers resistance to anti-PD1/PD-L1 therapy in lung cancer.
Cell Reports. Medicine
Alburquerque-Bejar, Juan J JJ; Navajas-Chocarro, Pablo P; Saigi, Maria M; Ferrero-Andres, Ana A; Morillas, Juan M JM; Vilarrubi, Andrea A; Gomez, Antonio A; Mate, José L JL; Munoz-Marmol, Ana M AM; Romero, Octavio A OA; Blecua, Pedro P; Davalos, Veronica V; Esteller, Manel M; Pros, Eva E; Llabata, Paula P; Torres-Diz, Manuel M; Esteve-Codina, Anna A; Sanchez-Cespedes, Montse M
Genomic Landscape of Primary Resistance to Osimertinib Among Hispanic Patients with EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC): Results of an Observational Longitudinal Cohort Study.
Targeted Oncology
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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA