Variant ID: 12-25398285-C-A

NM_033360.2(KRAS):c.34G>T;(p.Gly12Cys)

This variant was identified in 1458 publications




Publications:


Patient specific circulating tumor DNA fingerprints to monitor treatment response across multiple tumors.

Journal Of Translational Medicine
J Li, W Jiang, J Wei, J Zhang, L Cai, M Luo, Z Wang, W Sun, S Wang, C Wang, C Dai, J Liu, G Wang, J Wang, Q Xu, Y Deng
Publication Date: 2020-08-01

Variant appearance in text: KRAS: G12C
PMID: 32738923
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Recurrent Neoantigens in Colorectal Cancer as Potential Immunotherapy Targets.

Biomed Research International
C Chen, S Liu, R Qu, B Li
Publication Date: 2020

Variant appearance in text: KRAS: G12C
PMID: 32733937
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Genetic analysis in the clinical management of biliary tract cancer.

Annals Of Gastroenterological Surgery
T Wakai, M Nagahashi, Y Shimada, P Prasoon, J Sakata
Publication Date: 2020-07

Variant appearance in text: KRAS: G12C
PMID: 32724874
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Multitarget stool DNA test compared with fecal occult blood test for colorectal cancer screening.

Oncology Letters
C Yang, W Wu, Y Yang, X Yang, J Sun, W Zhang, K Liu, H Ying, S Jiang, X Yu, Y Shi, Y Zhou, S Zhu, Y Xu, Y Ding, L Xie, B Cai, X Xin, P Chen, R Zhao, Y Wu
Publication Date: 2020-08

Variant appearance in text: KRAS: Gly12Cys
PMID: 32724359
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Glutaminase Inhibition on NSCLC Depends on Extracellular Alanine Exploitation.

Cells
E Caiola, M Colombo, G Sestito, M Lupi, M Marabese, R Pastorelli, M Broggini, L Brunelli
Publication Date: 2020-07-23

Variant appearance in text: KRAS: G12C
PMID: 32718002
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Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer.

Nature Communications
L Aubert, N Nandagopal, Z Steinhart, G Lavoie, S Nourreddine, J Berman, MK Saba-El-Leil, D Papadopoli, S Lin, T Hart, G Macleod, I Topisirovic, L Gaboury, CJ Fahrni, D Schramek, S Meloche, S Angers, PP Roux
Publication Date: 2020-07-24

Variant appearance in text: KRAS: G12C
PMID: 32709883
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Identification of a Clinical Cutoff Value for Multiplex KRASG12/G13 Mutation Detection in Colorectal Adenocarcinoma Patients Using Digital Droplet PCR, and Comparison with Sanger Sequencing and PNA Clamping Assay.

Journal Of Clinical Medicine
KH Lee, TH Lee, MK Choi, IS Kwon, GE Bae, MK Yeo
Publication Date: 2020-07-18

Variant appearance in text: KRAS: G12C
PMID: 32708359
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Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR.

Scientific Reports
Y Ono, A Hayashi, C Maeda, M Suzuki, R Wada, H Sato, H Kawabata, T Okada, T Goto, H Karasaki, Y Mizukami, T Okumura
Publication Date: 2020-07-23

Variant appearance in text: KRAS: G12C
PMID: 32704002
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Characterization of Driver Mutations in Anaplastic Thyroid Carcinoma Identifies RAS and PIK3CA Mutations as Negative Survival Predictors.

Cancers
WA Lai, CY Liu, SY Lin, CC Chen, JF Hang
Publication Date: 2020-07-20

Variant appearance in text: KRAS: G12C
PMID: 32698386
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Ovarian mesonephric-like adenocarcinoma arising in serous borderline tumor: a case report with complex morphological and molecular analysis.

Diagnostic Pathology
P Dundr, M Gregová, K Němejcová, M Bártů, N Hájková, J Hojný, I Stružinská, D Fischerová
Publication Date: 2020-07-21

Variant appearance in text: KRAS: G12C
PMID: 32693840
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KRAS(G12C)-AMG 510 interaction dynamics revealed by all-atom molecular dynamics simulations.

Scientific Reports
T Pantsar
Publication Date: 2020-07-20

Variant appearance in text: KRAS: G12C
PMID: 32686745
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miRNAs-Based Molecular Signature for KRAS Mutated and Wild Type Colorectal Cancer: An Explorative Study.

Journal Of Immunology Research
E Milanesi, M Dobre, AI Bucuroiu, V Herlea, TE Manuc, A Salvi, G De Petro, M Manuc, G Becheanu
Publication Date: 2020

Variant appearance in text: KRAS: G12C
PMID: 32676506
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Personalized post-surgical care?-possible strategies for NSCLCs with EGFR mutation.

Translational Lung Cancer Research
K Suda
Publication Date: 2020-06

Variant appearance in text: KRAS: G12C
PMID: 32676308
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BRAF and KRAS mutations in metastatic colorectal cancer: future perspectives for personalized therapy.

Gastroenterology Report
ZN Li, L Zhao, LF Yu, MJ Wei
Publication Date: 2020-06

Variant appearance in text: KRAS: G12C
PMID: 32665851
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Anti-EGFR therapy in metastatic colorectal cancer: mechanisms and potential regimens of drug resistance.

Gastroenterology Report
QH Li, YZ Wang, J Tu, CW Liu, YJ Yuan, R Lin, WL He, SR Cai, YL He, JN Ye
Publication Date: 2020-06

Variant appearance in text: KRAS: G12C
PMID: 32665850
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Combinatorial Immunotherapies for Metastatic Colorectal Cancer.

Cancers
E Janssen, B Subtil, F de la Jara Ortiz, HMW Verheul, DVF Tauriello
Publication Date: 2020-07-12

Variant appearance in text: KRAS: G12C
PMID: 32664619
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Altering the response to radiation: radiosensitizers and targeted therapies in pancreatic ductal adenocarcinoma: preclinical and emerging clinical evidence.

Annals Of Pancreatic Cancer
AR Wolfe, TM Williams
Publication Date: 2018-08

Variant appearance in text: KRAS: G12C
PMID: 32656528
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Genomic characterization of Chinese ovarian clear cell carcinoma identifies driver genes by whole exome sequencing.

Neoplasia (New York, N.Y.)
Q Yang, C Zhang, Y Ren, H Yi, T Luo, F Xing, X Bai, L Cui, L Zhu, J Ouyang, P Jiang, W Fan, J Qiu, F Wang, X Xing, Z Zhang, X Zhang, R Zhang
Publication Date: 2020-07-07

Variant appearance in text: KRAS: G12C
PMID: 32650224
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Frequency of MET exon 14 skipping mutations in non-small cell lung cancer according to technical approach in routine diagnosis: results from a real-life cohort of 2,369 patients.

Journal Of Thoracic Disease
A Champagnac, PP Bringuier, M Barritault, S Isaac, E Watkin, F Forest, JM Maury, N Girard, M Brevet
Publication Date: 2020-05

Variant appearance in text: KRAS: G12C
PMID: 32642122
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Could Protons and Carbon Ions Be the Silver Bullets Against Pancreatic Cancer?

International Journal Of Molecular Sciences
C Huart, JW Chen, B Le Calvé, C Michiels, AC Wéra
Publication Date: 2020-07-04

Variant appearance in text: KRAS: G12C
PMID: 32635552
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Interleukin-1β and Cancer.

Cancers
C Rébé, F Ghiringhelli
Publication Date: 2020-07-04

Variant appearance in text: KRAS: G12C
PMID: 32635472
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Molecular matching and treatment strategies for advanced stage lung cancer at Dartmouth-Hitchcock Medical Center: A three-year review of a Molecular Tumor Board.

Practical Laboratory Medicine
EB Bernhardt, MD Chamberlin, IP Gorlov, FB de Abreu, KJ Bloch, JD Peterson, GJ Tsongalis, K Shirai, KH Dragnev, TW Miller, LJ Tafe
Publication Date: 2020-08

Variant appearance in text: KRAS: G12C
PMID: 32613070
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Reduced replication origin licensing selectively kills KRAS-mutant colorectal cancer cells via mitotic catastrophe.

Cell Death & Disease
B Gastl, K Klotz-Noack, B Klinger, S Ispasanie, KHF Salib, J Zuber, S Mamlouk, N Bublitz, N Blüthgen, D Horst, M Morkel, R Schäfer, C Sers
Publication Date: 2020-07-01

Variant appearance in text: KRAS: G12C
PMID: 32612138
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Clinical characteristics and prognostic value of the KRAS G12C mutation in Chinese non-small cell lung cancer patients.

Biomarker Research
SY Liu, H Sun, JY Zhou, GL Jie, Z Xie, Y Shao, X Zhang, JY Ye, CX Chen, XC Zhang, Q Zhou, JJ Yang, YL Wu
Publication Date: 2020

Variant appearance in text: KRAS: G12C
PMID: 32607238
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Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes-7.

Molecules (Basel, Switzerland)
M Gütschow, JJV Eynde, J Jampilek, C Kang, AA Mangoni, P Fossa, R Karaman, A Trabocchi, PJH Scott, J Reynisson, S Rapposelli, S Galdiero, JY Winum, C Brullo, K Prokai-Tatrai, AK Sharma, M Schapira, YT Azuma, L Cerchia, M Spetea, G Torri, S Collina, A Geronikaki, AT García-Sosa, MH Vasconcelos, ME Sousa, I Kosalec, T Tuccinardi, IF Duarte, JAR Salvador, M Bertinaria, M Pellecchia, J Amato, G Rastelli, PAC Gomes, RC Guedes, JM Sabatier, A Estévez-Braun, B Pagano, S Mangani, R Ragno, G Kokotos, M Brindisi, FV González, F Borges, M Miloso, J Rautio, D Muñoz-Torrero
Publication Date: 2020-06-28

Variant appearance in text: KRAS: G12C
PMID: 32605268
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Genetic Markers in Lung Cancer Diagnosis: A Review.

International Journal Of Molecular Sciences
K Wadowska, I Bil-Lula, Ł Trembecki, M Śliwińska-Mossoń
Publication Date: 2020-06-27

Variant appearance in text: KRAS: G12C
PMID: 32604993
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A potent KRAS macromolecule degrader specifically targeting tumours with mutant KRAS.

Nature Communications
N Bery, A Miller, T Rabbitts
Publication Date: 2020-06-26

Variant appearance in text: KRAS: G12C
PMID: 32591521
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Development of a cell-free split-luciferase biochemical assay as a tool for screening for inhibitors of challenging protein-protein interaction targets.

Wellcome Open Research
R Cooley, N Kara, NS Hui, J Tart, C Roustan, R George, DC Hancock, BF Binkowski, KV Wood, M Ismail, J Downward
Publication Date: 2020

Variant appearance in text: KRAS: G12C
PMID: 32587898
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Clinicopathological Characteristics and Mutation Spectrum of Colorectal Adenocarcinoma With Mucinous Component in a Chinese Cohort: Comparison With Classical Adenocarcinoma.

Frontiers In Oncology
J Chen, L Zhou, J Gao, T Lu, J Wang, H Wu, Z Liang
Publication Date: 2020

Variant appearance in text: KRAS: G12C
PMID: 32582557
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Small cell transformation of non-small cell lung cancer on immune checkpoint inhibitors: uncommon or under-recognized?

Journal For Immunotherapy Of Cancer
K Sehgal, A Varkaris, H Viray, PA VanderLaan, D Rangachari, DB Costa
Publication Date: 2020-06

Variant appearance in text: KRAS: G12C
PMID: 32581048
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Reassessing the role of high dose cytarabine and mitoxantrone in relapsed/refractory acute myeloid leukemia.

Oncotarget
J Canaani, M Nagar, G Heering, C Gefen, R Yerushalmi, N Shem-Tov, Y Volchek, D Merkel, A Avigdor, A Shimoni, N Amariglio, G Rechavi, A Nagler
Publication Date: 2020-06-09

Variant appearance in text: KRAS: G12C
PMID: 32577167
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Genome-wide DNA methylation analysis of KRAS mutant cell lines.

Scientific Reports
BY Tew, JK Durand, KL Bryant, TK Hayes, S Peng, NL Tran, GC Gooden, DN Buckley, CJ Der, AS Baldwin, B Salhia
Publication Date: 2020-06-23

Variant appearance in text: KRAS: G12C
PMID: 32576853
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FAM83G Is a Novel Inducer of Apoptosis.

Molecules (Basel, Switzerland)
J Okada, N Sunaga, E Yamada, T Saito, A Ozawa, Y Nakajima, K Okada, JE Pessin, S Okada, M Yamada
Publication Date: 2020-06-18

Variant appearance in text: KRAS: G12C
PMID: 32570757
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Hitting KRAS When It's Down.

Journal Of Medicinal Chemistry
R Gabizon, N London
Publication Date: 2020-06-22

Variant appearance in text: KRAS: G12C
PMID: 32568546
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Histology and its prognostic effect on KRAS-mutated colorectal carcinomas in Korea.

Oncology Letters
HS Lee, DY Hwang, HS Han
Publication Date: 2020-07

Variant appearance in text: KRAS: G12C
PMID: 32565990
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Targeting KRAS Mutant Non-Small-Cell Lung Cancer: Past, Present and Future.

International Journal Of Molecular Sciences
IZ Uras, HP Moll, E Casanova
Publication Date: 2020-06-17

Variant appearance in text: KRAS: G12C
PMID: 32560574
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Complex Oncological Decision-Making Utilizing Fast-and-Frugal Trees in a Community Setting-Role of Academic and Hybrid Modeling.

Journal Of Clinical Medicine
R Salgia, I Mambetsariev, T Tan, A Schwer, DP Pearlstein, H Chehabi, A Baroz, J Fricke, R Pharaon, H Romo, T Waddington, R Babikian, L Buck, P Kulkarni, M Cianfrocca, B Djulbegovic, SK Pal
Publication Date: 2020-06-16

Variant appearance in text: KRAS: G12C
PMID: 32560187
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Technical Evaluation of Commercial Mutation Analysis Platforms and Reference Materials for Liquid Biopsy Profiling.

Cancers
S Weber, B Spiegl, SO Perakis, CM Ulz, PM Abuja, K Kashofer, PV Leest, MA Azpurua, M Tamminga, D Brudzewsky, DG Rothwell, S Mohan, A Sartori, R Lampignano, Y Konigshofer, M Sprenger-Haussels, H Wikman, IR Bergheim, V Kloten, E Schuuring, MR Speicher, E Heitzer
Publication Date: 2020-06-16

Variant appearance in text: KRAS: G12C
PMID: 32560092
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Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers.

Cell Reports
I Ozkan-Dagliyan, JN Diehl, SD George, A Schaefer, B Papke, K Klotz-Noack, AM Waters, CM Goodwin, P Gautam, M Pierobon, S Peng, TSK Gilbert, KH Lin, O Dagliyan, K Wennerberg, EF Petricoin, NL Tran, SV Bhagwat, RV Tiu, SB Peng, LE Herring, LM Graves, C Sers, KC Wood, AD Cox, CJ Der
Publication Date: 2020-06-16

Variant appearance in text: KRAS: G12C
PMID: 32553168
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A novel hotspot and rare somatic mutation p.A138V, at TP53 is associated with poor survival of pancreatic ductal and periampullary adenocarcinoma patients.

Molecular Medicine (Cambridge, Mass.)
G Saha, R Singh, A Mandal, S Das, E Chattopadhyay, P Panja, P Roy, N DeSarkar, S Gulati, S Ghatak, S Ghosh, S Banerjee, B Roy, S Ghosh, D Chaudhuri, N Arora, NK Biswas, N Sikdar
Publication Date: 2020-06-17

Variant appearance in text: KRAS: G12C
PMID: 32552660
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Somatic Gain of KRAS Function in the Endothelium is Sufficient to Cause Vascular Malformations that Require MEK but not PI3K Signaling.

Circulation Research
JE Fish, CP Flores-Suarez, E Boudreau, AM Herman, MC Gutierrez, D Gustafson, PV DiStefano, M Cui, Z Chen, K Berman De Ruiz, TS Schexnayder, CS Ward, I Radovanovic, JD Wythe
Publication Date: 2020-06-17

Variant appearance in text: KRAS: G12C
PMID: 32552404
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Oncogenic Ras cooperates with knockdown of the tumor suppressor Lkb1 by RNAi to override organ size limits in Drosophila wing tissue.

Micropublication. Biology
BB Rackley, E Kiely, CS Seong, M Rupji, M Gilbert-Ross
Publication Date: 2020-03-03

Variant appearance in text: KRAS: G12C
PMID: 32550498
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Non-Small Cell Lung Cancer from Genomics to Therapeutics: A Framework for Community Practice Integration to Arrive at Personalized Therapy Strategies.

Journal Of Clinical Medicine
S Rajurkar, I Mambetsariev, R Pharaon, B Leach, T Tan, P Kulkarni, R Salgia
Publication Date: 2020-06-15

Variant appearance in text: KRAS: G12C
PMID: 32549358
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A Driver Never Works Alone-Interplay Networks of Mutant p53, MYC, RAS, and Other Universal Oncogenic Drivers in Human Cancer.

Cancers
M Grzes, M Oron, Z Staszczak, A Jaiswar, M Nowak-Niezgoda, D Walerych
Publication Date: 2020-06-11

Variant appearance in text: KRAS: G12C
PMID: 32545208
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Molecular mechanisms of thalidomide and its derivatives.

Proceedings Of The Japan Academy. Series B, Physical And Biological Sciences
T Ito, H Handa
Publication Date: 2020

Variant appearance in text: KRAS: G12C
PMID: 32522938
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Improved Outcome Prediction for Appendiceal Pseudomyxoma Peritonei by Integration of Cancer Cell and Stromal Transcriptional Profiles.

Cancers
C Isella, M Vaira, M Robella, SE Bellomo, G Picco, A Borsano, A Mignone, C Petti, R Porporato, AA Ulla, A Pisacane, A Sapino, M Simone, E Medico
Publication Date: 2020-06-08

Variant appearance in text: KRAS: G12C
PMID: 32521738
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A novel sensitive detection method for DNA methylation in circulating free DNA of pancreatic cancer.

Plos One
K Shinjo, K Hara, G Nagae, T Umeda, K Katsushima, M Suzuki, Y Murofushi, Y Umezu, I Takeuchi, S Takahashi, Y Okuno, K Matsuo, H Ito, S Tajima, H Aburatani, K Yamao, Y Kondo
Publication Date: 2020

Variant appearance in text: KRAS: G12C
PMID: 32520974
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Detection of Colorectal Cancer and Advanced Adenoma by Liquid Biopsy (Decalib Study): The ddPCR Challenge.

Cancers
A Junca, G Tachon, C Evrard, C Villalva, E Frouin, L Karayan-Tapon, D Tougeron
Publication Date: 2020-06-06

Variant appearance in text: KRAS: G12C
PMID: 32517177
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A first case report of clinical response to targeted therapy in a patient with primary myoepithelial carcinoma of the lung harboring EGFR exon 19 deletion.

Diagnostic Pathology
X Xie, X Lin, M Liu, Y Qin, M Ouyang, S Li, Y Gu, S Chen, J Xiang, C Zhou
Publication Date: 2020-06-06

Variant appearance in text: KRAS: Gly12Cys
PMID: 32505185
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Anti-Tumor Effects of Biomimetic Sulfated Glycosaminoglycans on Lung Adenocarcinoma Cells in 2D and 3D In Vitro Models.

Molecules (Basel, Switzerland)
N Al Matari, G Deeb, H Mshiek, A Sinjab, H Kadara, W Abou-Kheir, R Mhanna
Publication Date: 2020-06-03

Variant appearance in text: KRAS: G12C
PMID: 32503108
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An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer development.

Nature Communications
S Shankar, JC Tien, RF Siebenaler, S Chugh, VL Dommeti, S Zelenka-Wang, XM Wang, IJ Apel, J Waninger, S Eyunni, A Xu, M Mody, A Goodrum, Y Zhang, JJ Tesmer, R Mannan, X Cao, P Vats, S Pitchiaya, SJ Ellison, J Shi, C Kumar-Sinha, HC Crawford, AM Chinnaiyan
Publication Date: 2020-06-04

Variant appearance in text: KRAS: G12C
PMID: 32499547
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Pharmacogenomic Analysis Reveals CCNA2 as a Predictive Biomarker of Sensitivity to Polo-Like Kinase I Inhibitor in Gastric Cancer.

Cancers
Y Lee, CE Lee, S Oh, H Kim, J Lee, SB Kim, HS Kim
Publication Date: 2020-05-30

Variant appearance in text: KRAS: G12C
PMID: 32486290
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A H-REV107 Peptide Inhibits Tumor Growth and Interacts Directly with Oncogenic KRAS Mutants.

Cancers
CW Han, MS Jeong, SC Ha, SB Jang
Publication Date: 2020-05-30

Variant appearance in text: KRAS: G12C
PMID: 32486141
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The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer.

Cancers
SH Lee, Y Jeon, JH Kang, H Jang, H Lee, SY Kim
Publication Date: 2020-05-28

Variant appearance in text: KRAS: G12C
PMID: 32481524
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The Quest for Improving Treatment of Cancer of Unknown Primary (CUP) Through Molecularly-Driven Treatments: A Systematic Review.

Frontiers In Oncology
R Lombardo, F Tosi, A Nocerino, K Bencardino, V Gambi, R Ricotta, F Spina, S Siena, A Sartore-Bianchi
Publication Date: 2020

Variant appearance in text: KRAS: G12C
PMID: 32457826
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Small Molecule KRAS Inhibitors: The Future for Targeted Pancreatic Cancer Therapy?

Cancers
J Gillson, Y Ramaswamy, G Singh, AA Gorfe, N Pavlakis, J Samra, A Mittal, S Sahni
Publication Date: 2020-05-24

Variant appearance in text: KRAS: G12C
PMID: 32456277
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Application of Next-Generation Sequencing for the Genomic Characterization of Patients with Smoldering Myeloma.

Cancers
M Manzoni, V Marchica, P Storti, B Ziccheddu, G Sammarelli, G Todaro, F Pelizzoni, S Salerio, L Notarfranchi, A Pompa, L Baldini, N Bolli, A Neri, N Giuliani, M Lionetti
Publication Date: 2020-05-23

Variant appearance in text: KRAS: G12C
PMID: 32456143
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Emerging therapeutic agents for advanced non-small cell lung cancer.

Journal Of Hematology & Oncology
R Chen, R Manochakian, L James, AG Azzouqa, H Shi, Y Zhang, Y Zhao, K Zhou, Y Lou
Publication Date: 2020-05-24

Variant appearance in text: KRAS: G12C
PMID: 32448366
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Experimental Treatment of Mucinous Peritoneal Metastases Using Patient-Derived Xenograft Models.

Translational Oncology
KG Fleten, C Lund-Andersen, S Waagene, TW Abrahamsen, Y Mørch, K Boye, A Torgunrud, K Flatmark
Publication Date: 2020-05-21

Variant appearance in text: KRAS: G12C
PMID: 32447231
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Sorafenib and everolimus in patients with advanced solid tumors and KRAS-mutated NSCLC: A phase I trial with early pharmacodynamic FDG-PET assessment.

Cancer Medicine
L Nogova, C Mattonet, M Scheffler, M Taubert, M Gardizi, ML Sos, S Michels, RN Fischer, M Limburg, DSY Abdulla, T Persigehl, C Kobe, S Merkelbach-Bruse, J Franklin, H Backes, R Schnell, D Behringer, B Kaminsky, M Eichstaedt, C Stelzer, M Kinzig, F Sörgel, Y Tian, L Junge, AA Suleiman, S Frechen, D Rokitta, D Ouyang, U Fuhr, R Buettner, J Wolf
Publication Date: 2020-05-21

Variant appearance in text: KRAS: G12C
PMID: 32436621
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Predictive molecular pathology in the time of COVID-19.

Journal Of Clinical Pathology
U Malapelle, C De Luca, A Iaccarino, F Pepe, P Pisapia, M Russo, R Sgariglia, M Nacchio, E Vigliar, C Bellevicine, FC Schmitt, G Troncone
Publication Date: 2020-05-19

Variant appearance in text: KRAS: G12C
PMID: 32434770
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NADPH oxidase 1 is highly expressed in human large and small bowel cancers.

Plos One
J Lu, G Jiang, Y Wu, S Antony, JL Meitzler, A Juhasz, H Liu, K Roy, H Makhlouf, R Chuaqui, D Butcher, MM Konaté, JH Doroshow
Publication Date: 2020

Variant appearance in text: KRAS: G12C
PMID: 32428030
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Novel ALK-specific mRNA in situ hybridization assay for non-small-cell lung carcinoma.

Translational Lung Cancer Research
N Hirai, T Sasaki, S Okumura, M Sado, N Akiyama, M Kitada, H Takei, Y Ohsaki
Publication Date: 2020-04

Variant appearance in text: KRAS: G12C
PMID: 32420065
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Metachronous primary lung adenocarcinomas harboring distinct KRAS mutations.

Thoracic Cancer
Y Hu, S Ren, C Chen, Q Liang, F Yu, W Liu
Publication Date: 2020-05-16

Variant appearance in text: KRAS: G12C
PMID: 32415761
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Molecular-Biology-Driven Treatment for Metastatic Colorectal Cancer.

Cancers
E Lai, N Liscia, C Donisi, S Mariani, S Tolu, A Pretta, M Persano, G Pinna, F Balconi, A Pireddu, V Impera, M Dubois, M Migliari, D Spanu, G Saba, S Camera, F Musio, P Ziranu, M Puzzoni, L Demurtas, V Pusceddu, M Dettori, E Massa, F Atzori, M Dessì, G Astara, C Madeddu, M Scartozzi
Publication Date: 2020-05-13

Variant appearance in text: KRAS: G12C
PMID: 32413973
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Phenotypic screening using large-scale genomic libraries to identify drug targets for the treatment of cancer.

Oncology Letters
M Sato
Publication Date: 2020-06

Variant appearance in text: KRAS: G12C
PMID: 32391087
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Transcription and Translation Inhibitors in Cancer Treatment.

Frontiers In Chemistry
N Laham-Karam, GP Pinto, A Poso, P Kokkonen
Publication Date: 2020

Variant appearance in text: KRAS: G12C
PMID: 32373584
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The Roles of Frequently Mutated Genes of Pancreatic Cancer in Regulation of Tumor Microenvironment.

Technology In Cancer Research & Treatment
H Sun, B Zhang, H Li
Publication Date: 2020

Variant appearance in text: KRAS: G12C
PMID: 32372692
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Targeted RNA sequencing with touch imprint cytology samples for non-small cell lung cancer patients.

Thoracic Cancer
K Seto, K Masago, S Fujita, M Haneda, Y Horio, T Hida, H Kuroda, W Hosoda, KI Okubo
Publication Date: 2020-05-05

Variant appearance in text: KRAS: Gly12Cys
PMID: 32372482
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Pancreatic Cancer and Its Microenvironment-Recent Advances and Current Controversies.

International Journal Of Molecular Sciences
KB Stopa, AA Kusiak, MD Szopa, PE Ferdek, MA Jakubowska
Publication Date: 2020-05-01

Variant appearance in text: KRAS: G12C
PMID: 32370075
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Usefulness of Two Independent DNA and RNA Tissue-Based Multiplex Assays for the Routine Care of Advanced NSCLC Patients.

Cancers
E Marin, C Teixido, E Carmona-Rocha, R Reyes, A Arcocha, N Viñolas, M Rodríguez-Mues, C Cabrera, M Sánchez, I Vollmer, S Castillo, S Muñoz, IG Sullivan, A Rodriguez, M Garcia, S Alos, P Jares, A Martinez, A Prat, MÁ Molina-Vila, N Reguart
Publication Date: 2020-04-30

Variant appearance in text: KRAS: G12C
PMID: 32365867
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Targeting GSK3 and Associated Signaling Pathways Involved in Cancer.

Cells
P Duda, SM Akula, SL Abrams, LS Steelman, AM Martelli, L Cocco, S Ratti, S Candido, M Libra, G Montalto, M Cervello, A Gizak, D Rakus, JA McCubrey
Publication Date: 2020-04-30

Variant appearance in text: KRAS: G12C
PMID: 32365809
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Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non-small cell lung cancer: Analysis of over 8000 cases.

Cancer
PC Mack, KC Banks, CR Espenschied, RA Burich, OA Zill, CE Lee, JW Riess, SA Mortimer, A Talasaz, RB Lanman, DR Gandara
Publication Date: 2020-05-04

Variant appearance in text: KRAS: G12C
PMID: 32365229
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Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000256078.4 c.34G>T p.Gly12Cys missense_variant 2/6 -
ENST00000311936.3 c.34G>T p.Gly12Cys missense_variant 2/5 -
ENST00000556131.1 c.34G>T p.Gly12Cys missense_variant 2/3 -
ENST00000557334.1 c.34G>T p.Gly12Cys missense_variant 2/3 -
NM_001369786.1 c.34G>T p.Gly12Cys missense_variant 2/6 -
NM_001369787.1 c.34G>T p.Gly12Cys missense_variant 2/5 -
NM_004985.5 c.34G>T p.Gly12Cys missense_variant 2/5 -
NM_033360.4 c.34G>T p.Gly12Cys missense_variant 2/6 -