Publications:

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Structural Insights and Development of LRRK2 Inhibitors for Parkinson's Disease in the Last Decade.

Genes

Thakur, Gunjan G; Kumar, Vikas V; Lee, Keun Woo KW; Won, Chungkil C

Publication Date: 2022-08-11

Variant appearance in text: LRRK2: S1761R

PubMed Link: 36011337

Variant Present in the following documents:

• Main text
• genes-13-01426.pdf

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Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding.

The Biochemical Journal

Kalogeropulou, Alexia F AF; Purlyte, Elena E; Tonelli, Francesca F; Lange, Sven M SM; Wightman, Melanie M; Prescott, Alan R AR; Padmanabhan, Shalini S; Sammler, Esther E; Alessi, Dario R DR

Publication Date: 2022-09-16

Variant appearance in text: LRRK2: Ser1761Arg

PubMed Link: 35950872

Variant Present in the following documents:

• Main text
• BCJ-479-1759.pdf
• BCJ-479-1759-s1.pdf

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Cognitive Impairment in Genetic Parkinson's Disease.

Parkinson'S Disease

Planas-Ballvé, A A; Vilas, D D

Publication Date: 2021

Variant appearance in text: LRRK2: S1761R

PubMed Link: 35003622

Variant Present in the following documents:

• Main text
• PD2021-8610285.pdf

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Mind the Gap: LRRK2 Phenotypes in the Clinic vs. in Patient Cells.

Cells

Goveas, Liesel L; Mutez, Eugénie E; Chartier-Harlin, Marie-Christine MC; Taymans, Jean-Marc JM

Publication Date: 2021-04-22

Variant appearance in text: LRRK2: S1761R

PubMed Link: 33922322

Variant Present in the following documents:

• Main text

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The Current State-of-the Art of LRRK2-Based Biomarker Assay Development in Parkinson's Disease.

Frontiers In Neuroscience

Rideout, Hardy J HJ; Chartier-Harlin, Marie-Christine MC; Fell, Matthew J MJ; Hirst, Warren D WD; Huntwork-Rodriguez, Sarah S; Leyns, Cheryl E G CEG; Mabrouk, Omar S OS; Taymans, Jean-Marc JM

Publication Date: 2020

Variant appearance in text: LRRK2: Ser1761Arg

PubMed Link: 33013290

Variant Present in the following documents:

• Main text
• fnins-14-00865.pdf

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Genetics in Parkinson disease: Mendelian versus non-Mendelian inheritance.

Journal Of Neurochemistry

Hernandez, Dena G DG; Reed, Xylena X; Singleton, Andrew B AB

Publication Date: 2016-10

Variant appearance in text: LRRK2: S1761R

PubMed Link: 27090875

Variant Present in the following documents:

• Main text

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LRRK2: cause, risk, and mechanism.

Journal Of Parkinson'S Disease

Paisán-Ruiz, Coro C; Lewis, Patrick A PA; Singleton, Andrew B AB

Publication Date: 2013

Variant appearance in text: LRRK2: S1761R

PubMed Link: 23938341

Variant Present in the following documents:

• Main text
• nihms516093.pdf

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Novel Lrrk2-p.S1761R mutation is not a common cause of Parkinson's disease in Spain.

Movement Disorders : Official Journal Of The Movement Disorder Society

Mata, Ignacio F IF; Alvarez, Victoria V; Ribacoba, Renee R; Infante, Jon J; Sierra, María M; Gómez-Garre, Pilar P; Mir, Pablo P; Waldherr, Sarah S; Yearout, Dora D; Zabetian, Cyrus P CP

Publication Date: 2013-02

Variant appearance in text: LRRK2: 5281A>C; S1761R

PubMed Link: 23389884

Variant Present in the following documents:

• Main text

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