Evaluating the Potential of Polygenic Risk Score to Improve Colorectal Cancer Screening.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Arnau-Collell, Coral C; Díez-Villanueva, Anna A; Bellosillo, Beatriz B; Augé, Josep M JM; Muñoz, Jenifer J; Guinó, Elisabet E; Moreira, Leticia L; Serradesanferm, Anna A; Pozo, Àngels À; Torà-Rocamora, Isabel I; Bonjoch, Laia L; Ibañez-Sanz, Gemma G; Obon-Santacana, Mireia M; Moratalla-Navarro, Ferran F; Sanz-Pamplona, Rebeca R; Márquez Márquez, Carmen C; Rueda Miret, Rebeca R; Pérez Berbegal, Rocio R; Piquer Velasco, Gabriel G; Hernández Rodríguez, Cristina C; Grau, Jaume J; Castells, Antoni A; Borràs, Josep M JM; Bessa, Xavier X; Moreno, Victor V; Castellví-Bel, Sergi S
Non-Lynch Familial and Early-Onset Colorectal Cancer Explained by Accumulation of Low-Risk Genetic Variants.
Cancers
Mur, Pilar P; Bonifaci, Nuria N; Díez-Villanueva, Anna A; Munté, Elisabet E; Alonso, Maria Henar MH; Obón-Santacana, Mireia M; Aiza, Gemma G; Navarro, Matilde M; Piñol, Virginia V; Brunet, Joan J; Tomlinson, Ian I; Capellá, Gabriel G; Moreno, Victor V; Valle, Laura L
Colorectal cancer risk variants rs10161980 and rs7495132 are associated with cancer survival outcome by a recessive mode of inheritance.
International Journal Of Cancer
He, Yazhou Y; Timofeeva, Maria M; Zhang, Xiaomeng X; Xu, Wei W; Li, Xue X; Din, Farhat V N FVN; Svinti, Victoria V; Farrington, Susan M SM; Campbell, Harry H; Dunlop, Malcolm G MG; Theodoratou, Evropi E
Colorectal cancer genetic variants are also associated with serrated polyposis syndrome susceptibility.
Journal Of Medical Genetics
Arnau-Collell, Coral C; Soares de Lima, Yasmin Y; Díaz-Gay, Marcos M; Muñoz, Jenifer J; Carballal, Sabela S; Bonjoch, Laia L; Moreira, Leticia L; Lozano, Juan José JJ; Ocaña, Teresa T; Cuatrecasas, Miriam M; Díaz de Bustamante, Aranzazu A; Castells, Antoni A; Capellà, Gabriel G; Bujanda, Luis L; Cubiella, Joaquin J; Rodríguez-Alcalde, Daniel D; Balaguer, Francesc F; Ruiz-Ponte, Clara C; Valle, Laura L; Moreno, Victor V; Castellvi-Bel, Sergi S
Single nucleotide polymorphisms associated with susceptibility for development of colorectal cancer: Case-control study in a Basque population.
Plos One
Alegria-Lertxundi, Iker I; Aguirre, Carmelo C; Bujanda, Luis L; Fernández, Francisco Javier FJ; Polo, Francisco F; Ordovás, José M JM; Etxezarraga, M Carmen MC; Zabalza, Iñaki I; Larzabal, Mikel M; Portillo, Isabel I; de Pancorbo, Marian M MM; Palencia-Madrid, Leire L; Rocandio, Ana M AM; Arroyo-Izaga, Marta M
Effects of common genetic variants associated with colorectal cancer risk on survival outcomes after diagnosis: A large population-based cohort study.
International Journal Of Cancer
He, Yazhou Y; Theodoratou, Evropi E; Li, Xue X; Din, Farhat V N FVN; Vaughan-Shaw, Peter P; Svinti, Victoria V; Farrington, Susan M SM; Campbell, Harry H; Dunlop, Malcolm G MG; Timofeeva, Maria M
Association analyses identify 31 new risk loci for colorectal cancer susceptibility.
Nature Communications
Law, Philip J PJ; Timofeeva, Maria M; Fernandez-Rozadilla, Ceres C; Broderick, Peter P; Studd, James J; Fernandez-Tajes, Juan J; Farrington, Susan S; Svinti, Victoria V; Palles, Claire C; Orlando, Giulia G; Sud, Amit A; Holroyd, Amy A; Penegar, Steven S; Theodoratou, Evropi E; Vaughan-Shaw, Peter P; Campbell, Harry H; Zgaga, Lina L; Hayward, Caroline C; Campbell, Archie A; Harris, Sarah S; Deary, Ian J IJ; Starr, John J; Gatcombe, Laura L; Pinna, Maria M; Briggs, Sarah S; Martin, Lynn L; Jaeger, Emma E; Sharma-Oates, Archana A; East, James J; Leedham, Simon S; Arnold, Roland R; Johnstone, Elaine E; Wang, Haitao H; Kerr, David D; Kerr, Rachel R; Maughan, Tim T; Kaplan, Richard R; Al-Tassan, Nada N; Palin, Kimmo K; Hänninen, Ulrika A UA; Cajuso, Tatiana T; Tanskanen, Tomas T; Kondelin, Johanna J; Kaasinen, Eevi E; Sarin, Antti-Pekka AP; Eriksson, Johan G JG; Rissanen, Harri H; Knekt, Paul P; Pukkala, Eero E; Jousilahti, Pekka P; Salomaa, Veikko V; Ripatti, Samuli S; Palotie, Aarno A; Renkonen-Sinisalo, Laura L; Lepistö, Anna A; Böhm, Jan J; Mecklin, Jukka-Pekka JP; Buchanan, Daniel D DD; Win, Aung-Ko AK; Hopper, John J; Jenkins, Mark E ME; Lindor, Noralane M NM; Newcomb, Polly A PA; Gallinger, Steven S; Duggan, David D; Casey, Graham G; Hoffmann, Per P; Nöthen, Markus M MM; Jöckel, Karl-Heinz KH; Easton, Douglas F DF; Pharoah, Paul D P PDP; Peto, Julian J; Canzian, Federico F; Swerdlow, Anthony A; Eeles, Rosalind A RA; Kote-Jarai, Zsofia Z; Muir, Kenneth K; Pashayan, Nora N; , ; Harkin, Andrea A; Allan, Karen K; McQueen, John J; Paul, James J; Iveson, Timothy T; Saunders, Mark M; Butterbach, Katja K; Chang-Claude, Jenny J; Hoffmeister, Michael M; Brenner, Hermann H; Kirac, Iva I; Matošević, Petar P; Hofer, Philipp P; Brezina, Stefanie S; Gsur, Andrea A; Cheadle, Jeremy P JP; Aaltonen, Lauri A LA; Tomlinson, Ian I; Houlston, Richard S RS; Dunlop, Malcolm G MG
Genetic variant predictors of gene expression provide new insight into risk of colorectal cancer.
Human Genetics
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Nature Genetics
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The added value of genetic information in colorectal cancer risk prediction models: development and evaluation in the UK Biobank prospective cohort study.
British Journal Of Cancer
Smith, Todd T; Gunter, Marc J MJ; Tzoulaki, Ioanna I; Muller, David C DC
Determining Risk of Colorectal Cancer and Starting Age of Screening Based on Lifestyle, Environmental, and Genetic Factors.
Gastroenterology
Jeon, Jihyoun J; Du, Mengmeng M; Schoen, Robert E RE; Hoffmeister, Michael M; Newcomb, Polly A PA; Berndt, Sonja I SI; Caan, Bette B; Campbell, Peter T PT; Chan, Andrew T AT; Chang-Claude, Jenny J; Giles, Graham G GG; Gong, Jian J; Harrison, Tabitha A TA; Huyghe, Jeroen R JR; Jacobs, Eric J EJ; Li, Li L; Lin, Yi Y; Le Marchand, Loïc L; Potter, John D JD; Qu, Conghui C; Bien, Stephanie A SA; Zubair, Niha N; Macinnis, Robert J RJ; Buchanan, Daniel D DD; Hopper, John L JL; Cao, Yin Y; Nishihara, Reiko R; Rennert, Gad G; Slattery, Martha L ML; Thomas, Duncan C DC; Woods, Michael O MO; Prentice, Ross L RL; Gruber, Stephen B SB; Zheng, Yingye Y; Brenner, Hermann H; Hayes, Richard B RB; White, Emily E; Peters, Ulrike U; Hsu, Li L; ,
Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.
Oncotarget
Hofer, Philipp P; Hagmann, Michael M; Brezina, Stefanie S; Dolejsi, Erich E; Mach, Karl K; Leeb, Gernot G; Baierl, Andreas A; Buch, Stephan S; Sutterlüty-Fall, Hedwig H; Karner-Hanusch, Judith J; Bergmann, Michael M MM; Bachleitner-Hofmann, Thomas T; Stift, Anton A; Gerger, Armin A; Rötzer, Katharina K; Karner, Josef J; Stättner, Stefan S; Waldenberger, Melanie M; Meitinger, Thomas T; Strauch, Konstantin K; Linseisen, Jakob J; Gieger, Christian C; Frommlet, Florian F; Gsur, Andrea A
Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants.
Plos One
Du, Mengmeng M; Jiao, Shuo S; Bien, Stephanie A SA; Gala, Manish M; Abecasis, Goncalo G; Bezieau, Stephane S; Brenner, Hermann H; Butterbach, Katja K; Caan, Bette J BJ; Carlson, Christopher S CS; Casey, Graham G; Chang-Claude, Jenny J; Conti, David V DV; Curtis, Keith R KR; Duggan, David D; Gallinger, Steven S; Haile, Robert W RW; Harrison, Tabitha A TA; Hayes, Richard B RB; Hoffmeister, Michael M; Hopper, John L JL; Hudson, Thomas J TJ; Jenkins, Mark A MA; Küry, Sébastien S; Le Marchand, Loic L; Leal, Suzanne M SM; Newcomb, Polly A PA; Nickerson, Deborah A DA; Potter, John D JD; Schoen, Robert E RE; Schumacher, Fredrick R FR; Seminara, Daniela D; Slattery, Martha L ML; Hsu, Li L; Chan, Andrew T AT; White, Emily E; Berndt, Sonja I SI; Peters, Ulrike U
Genome-wide association study of colorectal cancer in Hispanics.
Carcinogenesis
Schmit, Stephanie L SL; Schumacher, Fredrick R FR; Edlund, Christopher K CK; Conti, David V DV; Ihenacho, Ugonna U; Wan, Peggy P; Van Den Berg, David D; Casey, Graham G; Fortini, Barbara K BK; Lenz, Heinz-Josef HJ; Tusié-Luna, Teresa T; Aguilar-Salinas, Carlos A CA; Moreno-Macías, Hortensia H; Huerta-Chagoya, Alicia A; Ordóñez-Sánchez, María Luisa ML; Rodríguez-Guillén, Rosario R; Cruz-Bautista, Ivette I; Rodríguez-Torres, Maribel M; Muñóz-Hernández, Linda Liliana LL; Arellano-Campos, Olimpia O; Gómez, Donají D; Alvirde, Ulices U; González-Villalpando, Clicerio C; González-Villalpando, María Elena ME; Le Marchand, Loic L; Haiman, Christopher A CA; Figueiredo, Jane C JC
Genetic Variants Associated with Colorectal Adenoma Susceptibility.
Plos One
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Quantifying the utility of single nucleotide polymorphisms to guide colorectal cancer screening.
Future Oncology (London, England)
Jenkins, Mark A MA; Makalic, Enes E; Dowty, James G JG; Schmidt, Daniel F DF; Dite, Gillian S GS; MacInnis, Robert J RJ; Ait Ouakrim, Driss D; Clendenning, Mark M; Flander, Louisa B LB; Stanesby, Oliver K OK; Hopper, John L JL; Win, Aung K AK; Buchanan, Daniel D DD
Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.
Scientific Reports
Cheng, Timothy H T TH; Thompson, Deborah D; Painter, Jodie J; O'Mara, Tracy T; Gorman, Maggie M; Martin, Lynn L; Palles, Claire C; Jones, Angela A; Buchanan, Daniel D DD; Win, Aung Ko AK; Hopper, John J; Jenkins, Mark M; Lindor, Noralane M NM; Newcomb, Polly A PA; Gallinger, Steve S; Conti, David D; Schumacher, Fred F; Casey, Graham G; Giles, Graham G GG; Pharoah, Paul P; Peto, Julian J; Cox, Angela A; Swerdlow, Anthony A; Couch, Fergus F; Cunningham, Julie M JM; Goode, Ellen L EL; Winham, Stacey J SJ; Lambrechts, Diether D; Fasching, Peter P; Burwinkel, Barbara B; Brenner, Hermann H; Brauch, Hiltrud H; Chang-Claude, Jenny J; Salvesen, Helga B HB; Kristensen, Vessela V; Darabi, Hatef H; Li, Jingmei J; Liu, Tao T; Lindblom, Annika A; Hall, Per P; de Polanco, Magdalena Echeverry ME; Sans, Monica M; Carracedo, Angel A; Castellvi-Bel, Sergi S; Rojas-Martinez, Augusto A; Aguiar Jnr, Samuel S; Teixeira, Manuel R MR; Dunning, Alison M AM; Dennis, Joe J; Otton, Geoffrey G; Proietto, Tony T; Holliday, Elizabeth E; Attia, John J; Ashton, Katie K; Scott, Rodney J RJ; McEvoy, Mark M; Dowdy, Sean C SC; Fridley, Brooke L BL; Werner, Henrica M J HM; Trovik, Jone J; Njolstad, Tormund S TS; Tham, Emma E; Mints, Miriam M; Runnebaum, Ingo I; Hillemanns, Peter P; Dörk, Thilo T; Amant, Frederic F; Schrauwen, Stefanie S; Hein, Alexander A; Beckmann, Matthias W MW; Ekici, Arif A; Czene, Kamila K; Meindl, Alfons A; Bolla, Manjeet K MK; Michailidou, Kyriaki K; Tyrer, Jonathan P JP; Wang, Qin Q; Ahmed, Shahana S; Healey, Catherine S CS; Shah, Mitul M; Annibali, Daniela D; Depreeuw, Jeroen J; Al-Tassan, Nada A NA; Harris, Rebecca R; Meyer, Brian F BF; Whiffin, Nicola N; Hosking, Fay J FJ; Kinnersley, Ben B; Farrington, Susan M SM; Timofeeva, Maria M; Tenesa, Albert A; Campbell, Harry H; Haile, Robert W RW; Hodgson, Shirley S; Carvajal-Carmona, Luis L; Cheadle, Jeremy P JP; Easton, Douglas D; Dunlop, Malcolm M; Houlston, Richard R; Spurdle, Amanda A; Tomlinson, Ian I
A model to determine colorectal cancer risk using common genetic susceptibility loci.
Gastroenterology
Hsu, Li L; Jeon, Jihyoun J; Brenner, Hermann H; Gruber, Stephen B SB; Schoen, Robert E RE; Berndt, Sonja I SI; Chan, Andrew T AT; Chang-Claude, Jenny J; Du, Mengmeng M; Gong, Jian J; Harrison, Tabitha A TA; Hayes, Richard B RB; Hoffmeister, Michael M; Hutter, Carolyn M CM; Lin, Yi Y; Nishihara, Reiko R; Ogino, Shuji S; Prentice, Ross L RL; Schumacher, Fredrick R FR; Seminara, Daniela D; Slattery, Martha L ML; Thomas, Duncan C DC; Thornquist, Mark M; Newcomb, Polly A PA; Potter, John D JD; Zheng, Yingye Y; White, Emily E; Peters, Ulrike U; , ; ,
Gene-environment interaction involving recently identified colorectal cancer susceptibility Loci.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Kantor, Elizabeth D ED; Hutter, Carolyn M CM; Minnier, Jessica J; Berndt, Sonja I SI; Brenner, Hermann H; Caan, Bette J BJ; Campbell, Peter T PT; Carlson, Christopher S CS; Casey, Graham G; Chan, Andrew T AT; Chang-Claude, Jenny J; Chanock, Stephen J SJ; Cotterchio, Michelle M; Du, Mengmeng M; Duggan, David D; Fuchs, Charles S CS; Giovannucci, Edward L EL; Gong, Jian J; Harrison, Tabitha A TA; Hayes, Richard B RB; Henderson, Brian E BE; Hoffmeister, Michael M; Hopper, John L JL; Jenkins, Mark A MA; Jiao, Shuo S; Kolonel, Laurence N LN; Le Marchand, Loic L; Lemire, Mathieu M; Ma, Jing J; Newcomb, Polly A PA; Ochs-Balcom, Heather M HM; Pflugeisen, Bethann M BM; Potter, John D JD; Rudolph, Anja A; Schoen, Robert E RE; Seminara, Daniela D; Slattery, Martha L ML; Stelling, Deanna L DL; Thomas, Fridtjof F; Thornquist, Mark M; Ulrich, Cornelia M CM; Warnick, Greg S GS; Zanke, Brent W BW; Peters, Ulrike U; Hsu, Li L; White, Emily E
Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis.
Human Molecular Genetics
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Joint effects of colorectal cancer susceptibility loci, circulating 25-hydroxyvitamin D and risk of colorectal cancer.
Plos One
Hiraki, Linda T LT; Joshi, Amit D AD; Ng, Kimmie K; Fuchs, Charles S CS; Ma, Jing J; Hazra, Aditi A; Peters, Ulrike U; Karlson, Elizabeth W EW; Giovannucci, Edward E; Kraft, Peter P; Chan, Andrew T AT
New genes emerging for colorectal cancer predisposition.
World Journal Of Gastroenterology
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Germline variants and advanced colorectal adenomas: adenoma prevention with celecoxib trial genome-wide association study.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
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Identification of Genetic Susceptibility Loci for Colorectal Tumors in a Genome-Wide Meta-analysis.
Gastroenterology
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