Publications:

---

Exploring the Structural and Functional Diversity among FGF Signals: A Comparative Study of Human, Mouse, and Xenopus FGF Ligands in Embryonic Development and Cancer Pathogenesis.

International Journal Of Molecular Sciences

Goutam, Ravi Shankar RS; Kumar, Vijay V; Lee, Unjoo U; Kim, Jaebong J

Publication Date: 2023-04-20

Variant appearance in text: FGF23: R176Q

PubMed Link: 37108717

Variant Present in the following documents:

• ijms-24-07556.pdf

View BVdb publication page

---

Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: FGF23: 527G>A; Arg176Gln

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

---

Aberrant phase separation and nucleolar dysfunction in rare genetic diseases.

Nature

Mensah, Martin A MA; Niskanen, Henri H; Magalhaes, Alexandre P AP; Basu, Shaon S; Kircher, Martin M; Sczakiel, Henrike L HL; Reiter, Alisa M V AMV; Elsner, Jonas J; Meinecke, Peter P; Biskup, Saskia S; Chung, Brian H Y BHY; Dombrowsky, Gregor G; Eckmann-Scholz, Christel C; Hitz, Marc Phillip MP; Hoischen, Alexander A; Holterhus, Paul-Martin PM; Hülsemann, Wiebke W; Kahrizi, Kimia K; Kalscheuer, Vera M VM; Kan, Anita A; Krumbiegel, Mandy M; Kurth, Ingo I; Leubner, Jonas J; Longardt, Ann Carolin AC; Moritz, Jörg D JD; Najmabadi, Hossein H; Skipalova, Karolina K; Snijders Blok, Lot L; Tzschach, Andreas A; Wiedersberg, Eberhard E; Zenker, Martin M; Garcia-Cabau, Carla C; Buschow, René R; Salvatella, Xavier X; Kraushar, Matthew L ML; Mundlos, Stefan S; Caliebe, Almuth A; Spielmann, Malte M; Horn, Denise D; Hnisz, Denes D

Publication Date: 2023-02-08

Variant appearance in text: FGF23: 527G>A; Arg176Gln

PubMed Link: 36755093

Variant Present in the following documents:

• 41586_2022_5682_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

---

Significance of logistic regression scoring model based on natural killer cell-mediated cytotoxic pathway in the diagnosis of colon cancer.

Frontiers In Immunology

Ye, Zhen Z; Zhang, Huanhuan H; Liang, Jianwei J; Yi, Shuying S; Zhan, Xianquan X

Publication Date: 2023

Variant appearance in text: FGF23: R176Q; rs104894347

PubMed Link: 36742322

Variant Present in the following documents:

• Table_8.xlsx, sheet 1

View BVdb publication page

---

Fibroblast growth factor 23 inhibits osteogenic differentiation and mineralization of chicken bone marrow mesenchymal stem cells.

Poultry Science

Lyu, Zhengtian Z; Li, Haifang H; Li, Xin X; Wang, Hui H; Jiao, Hongchao H; Wang, Xiaojuan X; Zhao, Jingpeng J; Lin, Hai H

Publication Date: 2022-10-25

Variant appearance in text: FGF23: R176Q

PubMed Link: 36442309

Variant Present in the following documents:

• main.pdf

View BVdb publication page

---

High sodium reduced the expression of PTH1R and Klotho by inhibiting 1,25(OH)2D3 synthesis in cultured proximal tubule epithelial cells.

Annals Of Translational Medicine

Gu, Jie J; Shi, Jialin J; Chen, Xujiao X; Mao, Jianping J; You, Huaizhou H; Chen, Jing J

Publication Date: 2022-05

Variant appearance in text: FGF23: R176Q

PubMed Link: 35928745

Variant Present in the following documents:

• atm-10-09-506.pdf

View BVdb publication page

---

High phosphate intake induces bone loss in nephrectomized thalassemic mice.

Plos One

Wanna-Udom, Sasithorn S; Luesiripong, Chainarong C; Sakunrangsit, Nithidol N; Metheepakornchai, Piyanuch P; Intharamonthian, Sitthichai S; Svasti, Saovaros S; Greenblatt, Matthew B MB; Leelahavanichkul, Asada A; Lotinun, Sutada S

Publication Date: 2022

Variant appearance in text: FGF23: R176Q

PubMed Link: 35622784

Variant Present in the following documents:

• pone.0268732.pdf

View BVdb publication page

---

Renoprotective effects of ferric citrate in a mouse model of chronic kidney disease.

Scientific Reports

Hanudel, Mark R MR; Czaya, Brian B; Wong, Shirley S; Jung, Grace G; Chua, Kristine K; Qiao, Bo B; Gabayan, Victoria V; Ganz, Tomas T

Publication Date: 2022-04-23

Variant appearance in text: FGF23: R176Q

PubMed Link: 35461329

Variant Present in the following documents:

• 41598_2022_Article_10842.pdf

View BVdb publication page

---

Are transient protein-protein interactions more dispensable?

Plos Computational Biology

Ghadie, Mohamed Ali MA; Xia, Yu Y

Publication Date: 2022-04

Variant appearance in text: FGF23: 527G>A; Arg176Gln

PubMed Link: 35404956

Variant Present in the following documents:

• pcbi.1010013.s002.xlsx, sheet 4

View BVdb publication page

---

Identification of a Novel Missense Mutation of the PHEX Gene in a Large Chinese Family with X-Linked Hypophosphataemia.

Frontiers In Genetics

Yang, Yanting Y; Wang, Yuanda Y; Shen, Ying Y; Liu, Mohan M; Dai, Siyu S; Wang, Xiaodong X; Liu, Hongqian H

Publication Date: 2022

Variant appearance in text: FGF23: R176q

PubMed Link: 35251124

Variant Present in the following documents:

• fgene-13-792183.pdf

View BVdb publication page

---

A review of ferric citrate clinical studies, and the rationale and design of the Ferric Citrate and Chronic Kidney Disease in Children (FIT4KiD) trial.

Pediatric Nephrology (Berlin, Germany)

Hanudel, Mark R MR; Laster, Marciana L ML; Portale, Anthony A AA; Dokras, Aditi A; Quigley, Raymond P RP; Guzman, German A Lozano GAL; Zaritsky, Joshua J JJ; Hayde, Nicole A NA; Kaskel, Frederick J FJ; Mitsnefes, Mark M MM; Ramirez, Jorge A JA; Imani, Peace D PD; Srivaths, Poyyapakkam R PR; Kogon, Amy J AJ; Denburg, Michelle R MR; Blydt-Hansen, Tom D TD; Reyes, Loretta Z LZ; Greenbaum, Larry A LA; Weidemann, Darcy K DK; Warady, Bradley A BA; Elashoff, David A DA; Mendley, Susan R SR; Isakova, Tamara T; Salusky, Isidro B IB

Publication Date: 2022-11

Variant appearance in text: FGF23: R176Q

PubMed Link: 35237863

Variant Present in the following documents:

• 467_2022_Article_5492.pdf

View BVdb publication page

---

Endocrine Fibroblast Growth Factors in Relation to Stress Signaling.

Cells

Shimizu, Makoto M; Sato, Ryuichiro R

Publication Date: 2022-02-01

Variant appearance in text: FGF23: R176Q

PubMed Link: 35159314

Variant Present in the following documents:

• cells-11-00505.pdf

View BVdb publication page

---

Tumor-induced osteomalacia: a case report.

Journal Of Medical Case Reports

Aligail, Khalid K; Dave, Joel A JA; Ross, Ian Louis IL

Publication Date: 2022-01-12

Variant appearance in text: FGF23: R176Q

PubMed Link: 35016725

Variant Present in the following documents:

• 13256_2021_Article_3220.pdf

View BVdb publication page

---

Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology

Li, Na N; Wang, Jiahong J; Zhan, Xianquan X

Publication Date: 2021

Variant appearance in text: FGF23: 527G>A; Arg176Gln

PubMed Link: 34887858

Variant Present in the following documents:

• Table_4.xlsx, sheet 1

View BVdb publication page

---

Autosomal Dominant Hypophosphatemic Rickets: A Case Report and Review of the Literature.

International Journal Of Environmental Research And Public Health

Mameli, Chiara C; Sangiorgio, Arianna A; Colombo, Valeria V; Gambino, Mirko M; Spaccini, Luigina L; Cattaneo, Elisa E; Zuccotti, Gian Vincenzo GV

Publication Date: 2021-08-19

Variant appearance in text: FGF23: 527G>A; R176Q; rs104894347

PubMed Link: 34444516

Variant Present in the following documents:

• Main text

View BVdb publication page

---

FAM20C Overview: Classic and Novel Targets, Pathogenic Variants and Raine Syndrome Phenotypes.

International Journal Of Molecular Sciences

Palma-Lara, Icela I; Pérez-Ramírez, Monserrat M; García Alonso-Themann, Patricia P; Espinosa-García, Ana María AM; Godinez-Aguilar, Ricardo R; Bonilla-Delgado, José J; López-Ornelas, Adolfo A; Victoria-Acosta, Georgina G; Olguín-García, María Guadalupe MG; Moreno, José J; Palacios-Reyes, Carmen C

Publication Date: 2021-07-27

Variant appearance in text: FGF23: R176Q

PubMed Link: 34360805

Variant Present in the following documents:

• Main text
• ijms-22-08039.pdf

View BVdb publication page

---

TIO Associated with Hyperparathyroidism: A Rarity, a Rule, or a Novel HPT-PMT Syndrome-A Case Study with Literature Review.

Case Reports In Endocrinology

Salim, Michael M; Behairy, Mohannad Samy MS; Barengolts, Elena E

Publication Date: 2021

Variant appearance in text: FGF23: R176Q

PubMed Link: 34354845

Variant Present in the following documents:

• CRIE2021-5172131.pdf

View BVdb publication page

---

In Vivo Analysis of the Contribution of Proprotein Convertases to the Processing of FGF23.

Frontiers In Endocrinology

Al Rifai, Omar O; Susan-Resiga, Delia D; Essalmani, Rachid R; Creemers, John W M JWM; Seidah, Nabil G NG; Ferron, Mathieu M

Publication Date: 2021

Variant appearance in text: FGF23: R176Q

PubMed Link: 34149625

Variant Present in the following documents:

• Main text
• fendo-12-690681.pdf

View BVdb publication page

---

The ABCs of the atypical Fam20 secretory pathway kinases.

The Journal Of Biological Chemistry

Worby, Carolyn A CA; Mayfield, Joshua E JE; Pollak, Adam J AJ; Dixon, Jack E JE; Banerjee, Sourav S

Publication Date: 2021

Variant appearance in text: FGF23: R176Q

PubMed Link: 33759783

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

---

Parenteral iron therapy and phosphorus homeostasis: A review.

American Journal Of Hematology

Kalantar-Zadeh, Kamyar K; Ganz, Tomas T; Trumbo, Henry H; Seid, Melvin H MH; Goodnough, Lawrence T LT; Levine, Michael A MA

Publication Date: 2021-05-01

Variant appearance in text: FGF23: R176Q

PubMed Link: 33471363

Variant Present in the following documents:

• AJH-96-606.pdf

View BVdb publication page

---

FGF23 contains two distinct high-affinity binding sites enabling bivalent interactions with α-Klotho.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Suzuki, Yoshihisa Y; Kuzina, Ekaterina E; An, Seong J SJ; Tome, Francisco F; Mohanty, Jyotidarsini J; Li, Wenxue W; Lee, Sangwon S; Liu, Yansheng Y; Lax, Irit I; Schlessinger, Joseph J

Publication Date: 2020-12-15

Variant appearance in text: FGF23: R176Q

PubMed Link: 33257569

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Osteocytic FGF23 and Its Kidney Function.

Frontiers In Endocrinology

Agoro, Rafiou R; Ni, Pu P; Noonan, Megan L ML; White, Kenneth E KE

Publication Date: 2020

Variant appearance in text: FGF23: R176Q

PubMed Link: 32982979

Variant Present in the following documents:

• Main text
• fendo-11-00592.pdf

View BVdb publication page

---

FGF/FGFR signaling in health and disease.

Signal Transduction And Targeted Therapy

Xie, Yangli Y; Su, Nan N; Yang, Jing J; Tan, Qiaoyan Q; Huang, Shuo S; Jin, Min M; Ni, Zhenhong Z; Zhang, Bin B; Zhang, Dali D; Luo, Fengtao F; Chen, Hangang H; Sun, Xianding X; Feng, Jian Q JQ; Qi, Huabing H; Chen, Lin L

Publication Date: 2020-09-02

Variant appearance in text: FGF23: R176Q

PubMed Link: 32879300

Variant Present in the following documents:

• 41392_2020_Article_222.pdf

View BVdb publication page

---

mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports

Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM

Publication Date: 2020-06-23

Variant appearance in text: FGF23: R176Q

PubMed Link: 32579932

Variant Present in the following documents:

• mmc5.xlsx, sheet 3

View BVdb publication page

---

Phosphorus Restriction Changes the Expression of Fibroblast Growth Factor 23 and Its Receptors in Laying Hens.

Frontiers In Physiology

Ren, Zhouzheng Z; Yan, Jiakun J; Hu, Qianli Q; Liu, Xinshuai X; Pan, Chong C; Liu, Yanli Y; Zhang, Xiaozhen X; Yang, Xin X; Yang, Xiaojun X

Publication Date: 2020

Variant appearance in text: FGF23: R176Q

PubMed Link: 32116791

Variant Present in the following documents:

• fphys-11-00085.pdf

View BVdb publication page

---

Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3.

Nature Chemical Biology

de Las Rivas, Matilde M; Paul Daniel, Earnest James EJ; Narimatsu, Yoshiki Y; Compañón, Ismael I; Kato, Kentaro K; Hermosilla, Pablo P; Thureau, Aurélien A; Ceballos-Laita, Laura L; Coelho, Helena H; Bernadó, Pau P; Marcelo, Filipa F; Hansen, Lars L; Maeda, Ryota R; Lostao, Anabel A; Corzana, Francisco F; Clausen, Henrik H; Gerken, Thomas A TA; Hurtado-Guerrero, Ramon R

Publication Date: 2020-03

Variant appearance in text: FGF23: R176Q

PubMed Link: 31932717

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Oral Iron for Prevention and Treatment of Rickets and Osteomalacia in Autosomal Dominant Hypophosphatemia.

Journal Of Bone And Mineral Research : The Official Journal Of The American Society For Bone And Mineral Research

Högler, Wolfgang W; Kapelari, Klaus K

Publication Date: 2020-02

Variant appearance in text: FGF23: R176Q

PubMed Link: 31834957

Variant Present in the following documents:

• Main text
• JBMR-35-0.pdf

View BVdb publication page

---

Oral Iron Replacement Normalizes Fibroblast Growth Factor 23 in Iron-Deficient Patients With Autosomal Dominant Hypophosphatemic Rickets.

Journal Of Bone And Mineral Research : The Official Journal Of The American Society For Bone And Mineral Research

Imel, Erik A EA; Liu, Ziyue Z; Coffman, Melissa M; Acton, Dena D; Mehta, Rakesh R; Econs, Michael J MJ

Publication Date: 2020-02

Variant appearance in text: FGF23: R176Q

PubMed Link: 31652009

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The FGF metabolic axis.

Frontiers Of Medicine

Li, Xiaokun X

Publication Date: 2019-10

Variant appearance in text: FGF23: R176Q

PubMed Link: 31495905

Variant Present in the following documents:

• 11684_2019_Article_711.pdf

View BVdb publication page

---

A G protein-coupled, IP3/protein kinase C pathway controlling the synthesis of phosphaturic hormone FGF23.

Jci Insight

He, Qing Q; Shumate, Lauren T LT; Matthias, Julia J; Aydin, Cumhur C; Wein, Marc N MN; Spatz, Jordan M JM; Goetz, Regina R; Mohammadi, Moosa M; Plagge, Antonius A; Divieti Pajevic, Paola P; Bastepe, Murat M

Publication Date: 2019-09-05

Variant appearance in text: FGF23: R176Q

PubMed Link: 31484825

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Estimating dispensable content in the human interactome.

Nature Communications

Ghadie, Mohamed M; Xia, Yu Y

Publication Date: 2019-07-19

Variant appearance in text: FGF23: 527G>A; Arg176Gln

PubMed Link: 31324802

Variant Present in the following documents:

• 41467_2019_11180_MOESM8_ESM.xlsx, sheet 4
• 41467_2019_11180_MOESM6_ESM.xlsx, sheet 4

View BVdb publication page

---

Regulation of Fibroblast Growth Factor 23 by Iron, EPO, and HIF.

Current Molecular Biology Reports

Wheeler, Jonathan A JA; Clinkenbeard, Erica L EL

Publication Date: 2019-03

Variant appearance in text: FGF23: R176Q

PubMed Link: 31218207

Variant Present in the following documents:

• Main text

View BVdb publication page

---

FGF23 Synthesis and Activity.

Current Molecular Biology Reports

Noonan, Megan L ML; White, Kenneth E KE

Publication Date: 2019-03

Variant appearance in text: FGF23: R176Q

PubMed Link: 31008021

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The EPO-FGF23 Signaling Pathway in Erythroid Progenitor Cells: Opening a New Area of Research.

Frontiers In Physiology

van Vuren, Annelies J AJ; Gaillard, Carlo A J M CAJM; Eisenga, Michele F MF; van Wijk, Richard R; van Beers, Eduard J EJ

Publication Date: 2019

Variant appearance in text: FGF23: R176Q

PubMed Link: 30971944

Variant Present in the following documents:

• Main text
• fphys-10-00304.pdf

View BVdb publication page

---

Autosomal Dominant Hypophosphatemic Rickets Presenting in a Phenotypically Normal Adult Female.

Case Reports In Endocrinology

Mualla, Hala H; Bae, Su Ah SA; Yaqub, Abid A

Publication Date: 2019

Variant appearance in text: FGF23: 527G>A; Arg176Gln

PubMed Link: 30949368

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Levels of Circulating Fibroblast Growth Factor 23 (FGF23) and Prognosis in Cancer Patients with Bone Metastases.

International Journal Of Molecular Sciences

Mansinho, André A; Ferreira, Arlindo R AR; Casimiro, Sandra S; Alho, Irina I; Vendrell, Inês I; Costa, Ana Lúcia AL; Sousa, Rita R; Abreu, Catarina C; Pulido, Catarina C; Macedo, Daniela D; Pacheco, Teresa R TR; Correia, Lurdes L; Costa, Luís L

Publication Date: 2019-02-06

Variant appearance in text: FGF23: R176Q

PubMed Link: 30736285

Variant Present in the following documents:

• ijms-20-00695.pdf

View BVdb publication page

---

Physiological regulation of phosphate by vitamin D, parathyroid hormone (PTH) and phosphate (Pi).

Pflugers Archiv : European Journal Of Physiology

Jacquillet, Grégory G; Unwin, Robert J RJ

Publication Date: 2019-01

Variant appearance in text: FGF23: R176Q

PubMed Link: 30393837

Variant Present in the following documents:

• 424_2018_Article_2231.pdf

View BVdb publication page

---

Autoimmune hyperphosphatemic tumoral calcinosis in a patient with FGF23 autoantibodies.

The Journal Of Clinical Investigation

Roberts, Mary Scott MS; Burbelo, Peter D PD; Egli-Spichtig, Daniela D; Perwad, Farzana F; Romero, Christopher J CJ; Ichikawa, Shoji S; Farrow, Emily E; Econs, Michael J MJ; Guthrie, Lori C LC; Collins, Michael T MT; Gafni, Rachel I RI

Publication Date: 2018-12-03

Variant appearance in text: FGF23: R176Q

PubMed Link: 30226830

Variant Present in the following documents:

• Main text

View BVdb publication page

---

FGF23 and Fetuin-A Interaction in the Liver and in the Circulation.

International Journal Of Biological Sciences

Mattinzoli, Deborah D; Ikehata, Masami M; Tsugawa, Koji K; Alfieri, Carlo M CM; Dongiovanni, Paola P; Trombetta, Elena E; Valenti, Luca L; Puliti, Aldamaria A; Lazzari, Lorenza L; Messa, Piergiorgio P

Publication Date: 2018

Variant appearance in text: FGF23: R176Q

PubMed Link: 29904273

Variant Present in the following documents:

• ijbsv14p0586.pdf

View BVdb publication page

---

Genetics of Refractory Rickets: Identification of Novel PHEX Mutations in Indian Patients and a Literature Update.

Journal Of Pediatric Genetics

Marik, Binata B; Bagga, Arvind A; Sinha, Aditi A; Hari, Pankaj P; Sharma, Arundhati A

Publication Date: 2018-06

Variant appearance in text: FGF23: R176Q

PubMed Link: 29707405

Variant Present in the following documents:

• Main text

View BVdb publication page

---

α-Klotho is a non-enzymatic molecular scaffold for FGF23 hormone signalling.

Nature

Chen, Gaozhi G; Liu, Yang Y; Goetz, Regina R; Fu, Lili L; Jayaraman, Seetharaman S; Hu, Ming-Chang MC; Moe, Orson W OW; Liang, Guang G; Li, Xiaokun X; Mohammadi, Moosa M

Publication Date: 2018-01-25

Variant appearance in text: FGF23: R176Q

PubMed Link: 29342138

Variant Present in the following documents:

• NIHMS927628-supplement-Supplementary_Table_1.pdf

View BVdb publication page

---

The metabolic bone disease associated with the Hyp mutation is independent of osteoblastic HIF1α expression.

Bone Reports

Hum, Julia M JM; Clinkenbeard, Erica L EL; Ip, Colin C; Cass, Taryn A TA; Allen, Matt M; White, Kenneth E KE

Publication Date: 2017-06

Variant appearance in text: FGF23: R176Q

PubMed Link: 28377980

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Acute Parathyroid Hormone Injection Increases C-Terminal but Not Intact Fibroblast Growth Factor 23 Levels.

Endocrinology

Knab, Vanessa M VM; Corbin, Braden B; Andrukhova, Olena O; Hum, Julia M JM; Ni, Pu P; Rabadi, Seham S; Maeda, Akira A; White, Kenneth E KE; Erben, Reinhold G RG; Jüppner, Harald H; Christov, Marta M

Publication Date: 2017-05-01

Variant appearance in text: FGF23: R176Q

PubMed Link: 28324013

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Heritable and acquired disorders of phosphate metabolism: Etiologies involving FGF23 and current therapeutics.

Bone

Clinkenbeard, Erica L EL; White, Kenneth E KE

Publication Date: 2017-09

Variant appearance in text: FGF23: R176Q

PubMed Link: 28159712

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Persistent fibroblast growth factor 23 signalling in the parathyroid glands for secondary hyperparathyroidism in mice with chronic kidney disease.

Scientific Reports

Kawakami, Kazuki K; Takeshita, Ai A; Furushima, Kenryo K; Miyajima, Masayasu M; Hatamura, Ikuji I; Kuro-O, Makoto M; Furuta, Yasuhide Y; Sakaguchi, Kazushige K

Publication Date: 2017-01-17

Variant appearance in text: FGF23: R176Q

PubMed Link: 28094278

Variant Present in the following documents:

• srep40534.pdf

View BVdb publication page

---

Dietary phosphate supplement does not rescue skeletal phenotype in a mouse model for craniometaphyseal dysplasia.

Journal Of Negative Results In Biomedicine

Liu, Yaling Y; Dutra, Eliane H EH; Reichenberger, Ernst J EJ; Chen, I-Ping IP

Publication Date: 2016-10-26

Variant appearance in text: FGF23: R176Q

PubMed Link: 27784318

Variant Present in the following documents:

• 12952_2016_Article_61.pdf

View BVdb publication page

---

A Landscape of Pharmacogenomic Interactions in Cancer.

Cell

Iorio, Francesco F; Knijnenburg, Theo A TA; Vis, Daniel J DJ; Bignell, Graham R GR; Menden, Michael P MP; Schubert, Michael M; Aben, Nanne N; Gonçalves, Emanuel E; Barthorpe, Syd S; Lightfoot, Howard H; Cokelaer, Thomas T; Greninger, Patricia P; van Dyk, Ewald E; Chang, Han H; de Silva, Heshani H; Heyn, Holger H; Deng, Xianming X; Egan, Regina K RK; Liu, Qingsong Q; Mironenko, Tatiana T; Mitropoulos, Xeni X; Richardson, Laura L; Wang, Jinhua J; Zhang, Tinghu T; Moran, Sebastian S; Sayols, Sergi S; Soleimani, Maryam M; Tamborero, David D; Lopez-Bigas, Nuria N; Ross-Macdonald, Petra P; Esteller, Manel M; Gray, Nathanael S NS; Haber, Daniel A DA; Stratton, Michael R MR; Benes, Cyril H CH; Wessels, Lodewyk F A LFA; Saez-Rodriguez, Julio J; McDermott, Ultan U; Garnett, Mathew J MJ

Publication Date: 2016-07-28

Variant appearance in text: FGF23: 527G>A; R176Q

PubMed Link: 27397505

Variant Present in the following documents:

• mmc3.xlsx, sheet 2

View BVdb publication page

---

Multiple faces of fibroblast growth factor-23.

Current Opinion In Nephrology And Hypertension

Han, Xiaobin X; Quarles, L Darryl LD

Publication Date: 2016-07

Variant appearance in text: FGF23: R176Q

PubMed Link: 27219044

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Systemic Control of Bone Homeostasis by FGF23 Signaling.

Current Molecular Biology Reports

Clinkenbeard, Erica L EL; White, Kenneth E KE

Publication Date: 2016-03-01

Variant appearance in text: FGF23: R176Q

PubMed Link: 27134818

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Calcium Extrusion Pump PMCA4: A New Player in Renal Calcium Handling?

Plos One

van Loon, Ellen P M EP; Little, Robert R; Prehar, Sukhpal S; Bindels, René J M RJ; Cartwright, Elizabeth J EJ; Hoenderop, Joost G J JG

Publication Date: 2016

Variant appearance in text: FGF23: R176Q

PubMed Link: 27101128

Variant Present in the following documents:

• pone.0153483.pdf

View BVdb publication page

---

CYP24 inhibition as a therapeutic target in FGF23-mediated renal phosphate wasting disorders.

The Journal Of Clinical Investigation

Bai, Xiuying X; Miao, Dengshun D; Xiao, Sophia S; Qiu, Dinghong D; St-Arnaud, René R; Petkovich, Martin M; Gupta, Ajay A; Goltzman, David D; Karaplis, Andrew C AC

Publication Date: 2016-02

Variant appearance in text: FGF23: R176Q

PubMed Link: 26784541

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Pruning the ricket thicket.

The Journal Of Clinical Investigation

David, Valentin V; Wolf, Myles M

Publication Date: 2016-02

Variant appearance in text: FGF23: R176Q

PubMed Link: 26784540

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Role of FGF/FGFR signaling in skeletal development and homeostasis: learning from mouse models.

Bone Research

Su, Nan N; Jin, Min M; Chen, Lin L

Publication Date: 2014

Variant appearance in text: FGF23: R176Q

PubMed Link: 26273516

Variant Present in the following documents:

• Main text

View BVdb publication page

---

FGF23 and Phosphate Wasting Disorders.

Bone Research

Huang, Xianglan X; Jiang, Yan Y; Xia, Weibo W

Publication Date: 2013-06

Variant appearance in text: FGF23: R176Q

PubMed Link: 26273497

Variant Present in the following documents:

• Main text

View BVdb publication page

---

GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: FGF23: R176Q

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 4

View BVdb publication page

---

Functional diversity of fibroblast growth factors in bone formation.

International Journal Of Endocrinology

Takei, Yuichiro Y; Minamizaki, Tomoko T; Yoshiko, Yuji Y

Publication Date: 2015

Variant appearance in text: FGF23: R176Q

PubMed Link: 25873956

Variant Present in the following documents:

• Main text
• IJE2015-729352.pdf

View BVdb publication page

---

The secretory pathway kinases.

Biochimica Et Biophysica Acta

Sreelatha, Anju A; Kinch, Lisa N LN; Tagliabracci, Vincent S VS

Publication Date: 2015-10

Variant appearance in text: FGF23: R176Q

PubMed Link: 25862977

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Age-related mutations associated with clonal hematopoietic expansion and malignancies.

Nature Medicine

Xie, Mingchao M; Lu, Charles C; Wang, Jiayin J; McLellan, Michael D MD; Johnson, Kimberly J KJ; Wendl, Michael C MC; McMichael, Joshua F JF; Schmidt, Heather K HK; Yellapantula, Venkata V; Miller, Christopher A CA; Ozenberger, Bradley A BA; Welch, John S JS; Link, Daniel C DC; Walter, Matthew J MJ; Mardis, Elaine R ER; Dipersio, John F JF; Chen, Feng F; Wilson, Richard K RK; Ley, Timothy J TJ; Ding, Li L

Publication Date: 2014-12

Variant appearance in text: FGF23: R176Q

PubMed Link: 25326804

Variant Present in the following documents:

• NIHMS630249-supplement-6.xlsx, sheet 1

View BVdb publication page

---

FGF23 is endogenously phosphorylated in bone cells.

Journal Of Bone And Mineral Research : The Official Journal Of The American Society For Bone And Mineral Research

Lindberg, Iris I; Pang, Hong Weng HW; Stains, Joseph P JP; Clark, David D; Yang, Austin J AJ; Bonewald, Lynda L; Li, Kevin Z KZ

Publication Date: 2015-03

Variant appearance in text: FGF23: R176Q

PubMed Link: 25195776

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Genetic rescue of glycosylation-deficient Fgf23 in the Galnt3 knockout mouse.

Endocrinology

Ichikawa, Shoji S; Gray, Amie K AK; Padgett, Leah R LR; Allen, Matthew R MR; Clinkenbeard, Erica L EL; Sarpa, Nicole M NM; White, Kenneth E KE; Econs, Michael J MJ

Publication Date: 2014-10

Variant appearance in text: FGF23: R176Q

PubMed Link: 25051439

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Hypophosphatemic rickets: revealing novel control points for phosphate homeostasis.

Current Osteoporosis Reports

White, Kenneth E KE; Hum, Julia M JM; Econs, Michael J MJ

Publication Date: 2014-09

Variant appearance in text: FGF23: R176Q

PubMed Link: 24980542

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Coupling fibroblast growth factor 23 production and cleavage: iron deficiency, rickets, and kidney disease.

Current Opinion In Nephrology And Hypertension

Wolf, Myles M; White, Kenneth E KE

Publication Date: 2014-07

Variant appearance in text: FGF23: R176Q

PubMed Link: 24867675

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Molecular bases of diseases characterized by hypophosphatemia and phosphaturia: new understanding.

Clinical Pediatric Endocrinology : Case Reports And Clinical Investigations : Official Journal Of The Japanese Society For Pediatric Endocrinology

Ozono, Keiichi K; Michigami, Toshimi T; Namba, Noriyuki N; Nakajima, Shigeo S; Yamamoto, Takehisa T

Publication Date: 2006

Variant appearance in text: FGF23: R176Q

PubMed Link: 24790333

Variant Present in the following documents:

• Main text
• cpe-15-129.pdf

View BVdb publication page

---

Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Tagliabracci, Vincent S VS; Engel, James L JL; Wiley, Sandra E SE; Xiao, Junyu J; Gonzalez, David J DJ; Nidumanda Appaiah, Hitesh H; Koller, Antonius A; Nizet, Victor V; White, Kenneth E KE; Dixon, Jack E JE

Publication Date: 2014-04-15

Variant appearance in text: FGF23: R176Q

PubMed Link: 24706917

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Reduced renal α-Klotho expression in CKD patients and its effect on renal phosphate handling and vitamin D metabolism.

Plos One

Sakan, Hirokazu H; Nakatani, Kimihiko K; Asai, Osamu O; Imura, Akihiro A; Tanaka, Tomohiro T; Yoshimoto, Shuhei S; Iwamoto, Noriyuki N; Kurumatani, Norio N; Iwano, Masayuki M; Nabeshima, Yo-Ichi Y; Konishi, Noboru N; Saito, Yoshihiko Y

Publication Date: 2014

Variant appearance in text: FGF23: R176Q

PubMed Link: 24466013

Variant Present in the following documents:

• Main text
• pone.0086301.pdf

View BVdb publication page

---

FGF-23 regulates CYP27B1 transcription in the kidney and in extra-renal tissues.

Plos One

Chanakul, Ankanee A; Zhang, Martin Y H MY; Louw, Andrew A; Armbrecht, Harvey J HJ; Miller, Walter L WL; Portale, Anthony A AA; Perwad, Farzana F

Publication Date: 2013

Variant appearance in text: FGF23: R176Q

PubMed Link: 24019880

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Neonatal iron deficiency causes abnormal phosphate metabolism by elevating FGF23 in normal and ADHR mice.

Journal Of Bone And Mineral Research : The Official Journal Of The American Society For Bone And Mineral Research

Clinkenbeard, Erica L EL; Farrow, Emily G EG; Summers, Lelia J LJ; Cass, Taryn A TA; Roberts, Jessica L JL; Bayt, Christine A CA; Lahm, Tim T; Albrecht, Marjorie M; Allen, Matthew R MR; Peacock, Munro M; White, Kenneth E KE

Publication Date: 2014-02

Variant appearance in text: FGF23: R176Q

PubMed Link: 23873717

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Exome and whole-genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity.

Nature Genetics

Dulak, Austin M AM; Stojanov, Petar P; Peng, Shouyong S; Lawrence, Michael S MS; Fox, Cameron C; Stewart, Chip C; Bandla, Santhoshi S; Imamura, Yu Y; Schumacher, Steven E SE; Shefler, Erica E; McKenna, Aaron A; Carter, Scott L SL; Cibulskis, Kristian K; Sivachenko, Andrey A; Saksena, Gordon G; Voet, Douglas D; Ramos, Alex H AH; Auclair, Daniel D; Thompson, Kristin K; Sougnez, Carrie C; Onofrio, Robert C RC; Guiducci, Candace C; Beroukhim, Rameen R; Zhou, Zhongren Z; Lin, Lin L; Lin, Jules J; Reddy, Rishindra R; Chang, Andrew A; Landrenau, Rodney R; Pennathur, Arjun A; Ogino, Shuji S; Luketich, James D JD; Golub, Todd R TR; Gabriel, Stacey B SB; Lander, Eric S ES; Beer, David G DG; Godfrey, Tony E TE; Getz, Gad G; Bass, Adam J AJ

Publication Date: 2013-05

Variant appearance in text: FGF23: 527G>A; R176Q

PubMed Link: 23525077

Variant Present in the following documents:

• NIHMS474888-supplement-5.xlsx, sheet 1

View BVdb publication page

---

Osteocyte regulation of phosphate homeostasis and bone mineralization underlies the pathophysiology of the heritable disorders of rickets and osteomalacia.

Bone

Feng, Jian Q JQ; Clinkenbeard, Erica L EL; Yuan, Baozhi B; White, Kenneth E KE; Drezner, Marc K MK

Publication Date: 2013-06

Variant appearance in text: FGF23: R176Q

PubMed Link: 23403405

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Fibroblast growth factor 23 is not associated with and does not induce arterial calcification.

Kidney International

Scialla, Julia J JJ; Lau, Wei Ling WL; Reilly, Muredach P MP; Isakova, Tamara T; Yang, Hsueh-Ying HY; Crouthamel, Matthew H MH; Chavkin, Nicholas W NW; Rahman, Mahboob M; Wahl, Patricia P; Amaral, Ansel P AP; Hamano, Takayuki T; Master, Stephen R SR; Nessel, Lisa L; Chai, Boyang B; Xie, Dawei D; Kallem, Radhakrishna R RR; Chen, Jing J; Lash, James P JP; Kusek, John W JW; Budoff, Matthew J MJ; Giachelli, Cecilia M CM; Wolf, Myles M; ,

Publication Date: 2013-06

Variant appearance in text: FGF23: R176Q

PubMed Link: 23389416

Variant Present in the following documents:

• Main text

View BVdb publication page

---