A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Jang, H Josh HJ; Hostetter, Galen G; MacFarlane, Alexander W AW; Madaj, Zachary Z; Ross, Eric A EA; Hinoue, Toshinori T; Kulchycki, Justin R JR; Burgos, Ryan S RS; Tafseer, Mahvish M; Alpaugh, R Katherine RK; Schwebel, Candice L CL; Kokate, Rutika R; Geynisman, Daniel M DM; Zibelman, Matthew R MR; Ghatalia, Pooja P; Nichols, Peter W PW; Chung, Woonbok W; Madzo, Jozef J; Hahn, Noah M NM; Quinn, David I DI; Issa, Jean-Pierre J JJ; Topper, Michael J MJ; Baylin, Stephen B SB; Shen, Hui H; Campbell, Kerry S KS; Jones, Peter A PA; Plimack, Elizabeth R ER
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.
Scientific Reports
Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA
Clonal dynamics of haematopoiesis across the human lifespan.
Nature
Mitchell, Emily E; Spencer Chapman, Michael M; Williams, Nicholas N; Dawson, Kevin J KJ; Mende, Nicole N; Calderbank, Emily F EF; Jung, Hyunchul H; Mitchell, Thomas T; Coorens, Tim H H THH; Spencer, David H DH; Machado, Heather H; Lee-Six, Henry H; Davies, Megan M; Hayler, Daniel D; Fabre, Margarete A MA; Mahbubani, Krishnaa K; Abascal, Federico F; Cagan, Alex A; Vassiliou, George S GS; Baxter, Joanna J; Martincorena, Inigo I; Stratton, Michael R MR; Kent, David G DG; Chatterjee, Krishna K; Parsy, Kourosh Saeb KS; Green, Anthony R AR; Nangalia, Jyoti J; Laurenti, Elisa E; Campbell, Peter J PJ
Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells.
Npj Systems Biology And Applications
Immanuel, Selva Rupa Christinal SRC; Ghanate, Avinash D AD; Parmar, Dharmeshkumar S DS; Yadav, Ritu R; Uthup, Riya R; Panchagnula, Venkateswarlu V; Raghunathan, Anu A
Publication Date: 2021-01-08
Variant appearance in text: DIP2B: T639T; rs11169524
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Publication Date: 2019-10-09
Variant appearance in text: DIP2B: T639T; rs11169524
A likely pathogenic variant putatively affecting splicing of PIGA identified in a multiple congenital anomalies hypotonia-seizures syndrome 2 (MCAHS2) family pedigree via whole-exome sequencing.
Fine-Mapping of Common Genetic Variants Associated with Colorectal Tumor Risk Identified Potential Functional Variants.
Plos One
Du, Mengmeng M; Jiao, Shuo S; Bien, Stephanie A SA; Gala, Manish M; Abecasis, Goncalo G; Bezieau, Stephane S; Brenner, Hermann H; Butterbach, Katja K; Caan, Bette J BJ; Carlson, Christopher S CS; Casey, Graham G; Chang-Claude, Jenny J; Conti, David V DV; Curtis, Keith R KR; Duggan, David D; Gallinger, Steven S; Haile, Robert W RW; Harrison, Tabitha A TA; Hayes, Richard B RB; Hoffmeister, Michael M; Hopper, John L JL; Hudson, Thomas J TJ; Jenkins, Mark A MA; Küry, Sébastien S; Le Marchand, Loic L; Leal, Suzanne M SM; Newcomb, Polly A PA; Nickerson, Deborah A DA; Potter, John D JD; Schoen, Robert E RE; Schumacher, Fredrick R FR; Seminara, Daniela D; Slattery, Martha L ML; Hsu, Li L; Chan, Andrew T AT; White, Emily E; Berndt, Sonja I SI; Peters, Ulrike U
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Publication Date: 2015-12-08
Variant appearance in text: DIP2B: T639T; rs11169524
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Publication Date: 2014
Variant appearance in text: DIP2B: T639T; rs11169524
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.
Nature Genetics
Houlston, Richard S RS; Cheadle, Jeremy J; Dobbins, Sara E SE; Tenesa, Albert A; Jones, Angela M AM; Howarth, Kimberley K; Spain, Sarah L SL; Broderick, Peter P; Domingo, Enric E; Farrington, Susan S; Prendergast, James G D JG; Pittman, Alan M AM; Theodoratou, Evi E; Smith, Christopher G CG; Olver, Bianca B; Walther, Axel A; Barnetson, Rebecca A RA; Churchman, Michael M; Jaeger, Emma E M EE; Penegar, Steven S; Barclay, Ella E; Martin, Lynn L; Gorman, Maggie M; Mager, Rachel R; Johnstone, Elaine E; Midgley, Rachel R; Niittymäki, Iina I; Tuupanen, Sari S; Colley, James J; Idziaszczyk, Shelley S; , ; Thomas, Huw J W HJ; Lucassen, Anneke M AM; Evans, D Gareth R DG; Maher, Eamonn R ER; , ; , ; , ; Maughan, Timothy T; Dimas, Antigone A; Dermitzakis, Emmanouil E; Cazier, Jean-Baptiste JB; Aaltonen, Lauri A LA; Pharoah, Paul P; Kerr, David J DJ; Carvajal-Carmona, Luis G LG; Campbell, Harry H; Dunlop, Malcolm G MG; Tomlinson, Ian P M IP