Publications:

---

Immunization with nanovaccines containing mutated K-Ras peptides and imiquimod aggravates heterotopic pancreatic cancer induced in mice.

Frontiers In Immunology

Martínez-Pérez, Amparo A; Diego-González, Lara L; Vilanova, Manuel M; Correia, Alexandra A; Simón-Vázquez, Rosana R; González-Fernández, África Á

Publication Date: 2023

Variant appearance in text: CS: G12V

PubMed Link: 37122717

Variant Present in the following documents:

• Main text
• fimmu-14-1153724.pdf

View BVdb publication page

---

Conserved microRNAs and Flipons Shape Gene Expression during Development by Altering Promoter Conformations.

International Journal Of Molecular Sciences

Herbert, Alan A; Pavlov, Fedor F; Konovalov, Dmitrii D; Poptsova, Maria M

Publication Date: 2023-03-03

Variant appearance in text: CS: G12V

PubMed Link: 36902315

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Increased osteoclastogenesis contributes to bone loss in the Costello syndrome Hras G12V mouse model.

Frontiers In Cell And Developmental Biology

Nandi, Sayantan S; Chennappan, Saravanakkumar S; Andrasch, Yannik Y; Fidan, Miray M; Engler, Melanie M; Ahmad, Mubashir M; Tuckermann, Jan P JP; Zenker, Martin M; Cirstea, Ion Cristian IC

Publication Date: 2022

Variant appearance in text: CS: G12V

PubMed Link: 36330334

Variant Present in the following documents:

• Main text
• fcell-10-1000575.pdf

View BVdb publication page

---

Gradient tracking in mating yeast depends on Bud1 inactivation and actin-independent vesicle delivery.

The Journal Of Cell Biology

Wang, Xin X; Pai, Chih-Yu CY; Stone, David E DE

Publication Date: 2022-12-05

Variant appearance in text: CS: G12V

PubMed Link: 36156058

Variant Present in the following documents:

• Main text
• JCB_202203004.pdf

View BVdb publication page

---

A Phase I-II multicenter trial with Avelumab plus autologous dendritic cell vaccine in pre-treated mismatch repair-proficient (MSS) metastatic colorectal cancer patients; GEMCAD 1602 study.

Cancer Immunology, Immunotherapy : Cii

Español-Rego, Marta M; Fernández-Martos, Carlos C; Elez, Elena E; Foguet, Carles C; Pedrosa, Leire L; Rodríguez, Nuria N; Ruiz-Casado, Ana A; Pineda, Estela E; Cid, Joan J; Cabezón, Raquel R; Oliveres, Helena H; Lozano, Miquel M; Ginés, Angels A; García-Criado, Angeles A; Ayuso, Juan Ramon JR; Pagés, Mario M; Cuatrecasas, Miriam M; Torres, Ferràn F; Thomson, Timothy T; Cascante, Marta M; Benítez-Ribas, Daniel D; Maurel, Joan J

Publication Date: 2022-09-09

Variant appearance in text: CS: G12V

PubMed Link: 36083313

Variant Present in the following documents:

• 262_2022_Article_3283.pdf

View BVdb publication page

---

State of the Art in Carbon Nanomaterials for Photoacoustic Imaging.

Biomedicines

Kang, Moon Sung MS; Lee, Haeni H; Jeong, Seung Jo SJ; Eom, Tae Joong TJ; Kim, Jeesu J; Han, Dong-Wook DW

Publication Date: 2022-06-10

Variant appearance in text: CS: G12V

PubMed Link: 35740396

Variant Present in the following documents:

• Main text
• biomedicines-10-01374.pdf

View BVdb publication page

---

Deletion of Lactate Dehydrogenase-A Impairs Oncogene-Induced Mouse Hepatocellular Carcinoma Development.

Cellular And Molecular Gastroenterology And Hepatology

Serra, Marina M; Di Matteo, Mario M; Serneels, Jens J; Pal, Rajesh R; Cafarello, Sarah Trusso ST; Lanza, Martina M; Sanchez-Martin, Carlos C; Evert, Matthias M; Castegna, Alessandra A; Calvisi, Diego Francesco DF; Mazzone, Massimiliano M; Columbano, Amedeo A

Publication Date: 2022

Variant appearance in text: CS: G12V

PubMed Link: 35714859

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Interactions between EGFR and EphA2 promote tumorigenesis through the action of Ephexin1.

Cell Death & Disease

Kim, Jeeho J; Chang, In-Youb IY; You, Ho Jin HJ

Publication Date: 2022-06-06

Variant appearance in text: CS: G12V

PubMed Link: 35668076

Variant Present in the following documents:

• 41419_2022_Article_4984.pdf

View BVdb publication page

---

The RASopathies: from pathogenetics to therapeutics.

Disease Models & Mechanisms

Hebron, Katie E KE; Hernandez, Edjay Ralph ER; Yohe, Marielle E ME

Publication Date: 2022-02-01

Variant appearance in text: CS: G12V

PubMed Link: 35178568

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Design and Application of Near-Infrared Nanomaterial-Liposome Hybrid Nanocarriers for Cancer Photothermal Therapy.

Pharmaceutics

Liang, Pan P; Mao, Linshen L; Dong, Yanli Y; Zhao, Zhenwen Z; Sun, Qin Q; Mazhar, Maryam M; Ma, Yining Y; Yang, Sijin S; Ren, Wei W

Publication Date: 2021-12-03

Variant appearance in text: CS: G12V

PubMed Link: 34959351

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Design and Application of Near-Infrared Nanomaterial-Liposome Hybrid Nanocarriers for Cancer Photothermal Therapy.

Pharmaceutics

Liang, Pan P; Mao, Linshen L; Dong, Yanli Y; Zhao, Zhenwen Z; Sun, Qin Q; Mazhar, Maryam M; Ma, Yining Y; Yang, Sijin S; Ren, Wei W

Publication Date: 2021-12-03

Variant appearance in text: CS: G12V

PubMed Link: 34959351

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Two-Way Development of the Genetic Model for Endometrial Tumorigenesis in Mice: Current and Future Perspectives.

Frontiers In Genetics

Maru, Yoshiaki Y; Hippo, Yoshitaka Y

Publication Date: 2021

Variant appearance in text: CS: G12V

PubMed Link: 34956336

Variant Present in the following documents:

• Main text
• fgene-12-798628.pdf

View BVdb publication page

---

Pharmacological effects of Picrasma quassioides (D. Don) Benn for inflammation, cancer and neuroprotection (Review).

Experimental And Therapeutic Medicine

Lee, Jaihyung J; Gong, Yi-Xi YX; Jeong, Hyunjeong H; Seo, Hoyoung H; Xie, Dan-Ping DP; Sun, Hu-Nan HN; Kwon, Taeho T

Publication Date: 2021-12

Variant appearance in text: CS: G12V

PubMed Link: 34659503

Variant Present in the following documents:

• etm-22-06-10792.pdf

View BVdb publication page

---

MEK-inhibitor-mediated rescue of skeletal myopathy caused by activating Hras mutation in a Costello syndrome mouse model.

Disease Models & Mechanisms

Tidyman, William E WE; Goodwin, Alice F AF; Maeda, Yoshiko Y; Klein, Ophir D OD; Rauen, Katherine A KA

Publication Date: 2022-02-01

Variant appearance in text: CS: 35G>T

PubMed Link: 34553752

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Molecular and Metabolic Reprogramming: Pulling the Strings Toward Tumor Metastasis.

Frontiers In Oncology

Hipólito, Ana A; Martins, Filipa F; Mendes, Cindy C; Lopes-Coelho, Filipa F; Serpa, Jacinta J

Publication Date: 2021

Variant appearance in text: CS: G12V

PubMed Link: 34150624

Variant Present in the following documents:

• fonc-11-656851.pdf

View BVdb publication page

---

Costello syndrome with special cutaneous manifestations and HRAS G12D mutation: A case report and literature review.

Molecular Genetics & Genomic Medicine

Qian, Wen W; Zhang, Meijie M; Huang, Hequn H; Chen, Yihe Y; Park, Gajin G; Zeng, Ni N; Li, Yueyue Y; Lu, Qian Q; Luo, Dan D

Publication Date: 2021-06

Variant appearance in text: CS: 35G>T; G12V

PubMed Link: 33932139

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Embryonic Expression of NrasG 12 D Leads to Embryonic Lethality and Cardiac Defects.

Frontiers In Cell And Developmental Biology

You, Xiaona X; Ryu, Myung-Jeom MJ; Cho, Eunjin E; Sang, Yanzhi Y; Damnernsawad, Alisa A; Zhou, Yun Y; Liu, Yangang Y; Zhang, Jing J; Lee, Youngsook Y

Publication Date: 2021

Variant appearance in text: CS: G12V

PubMed Link: 33681212

Variant Present in the following documents:

• Main text
• fcell-09-633661.pdf

View BVdb publication page

---

Indirect cholinergic activation slows down pancreatic cancer growth and tumor-associated inflammation.

Journal Of Experimental & Clinical Cancer Research : Cr

Pfitzinger, Paulo L PL; Fangmann, Laura L; Wang, Kun K; Demir, Elke E; Gürlevik, Engin E; Fleischmann-Mundt, Bettina B; Brooks, Jennifer J; D'Haese, Jan G JG; Teller, Steffen S; Hecker, Andreas A; Jesinghaus, Moritz M; Jäger, Carsten C; Ren, Lei L; Istvanffy, Rouzanna R; Kühnel, Florian F; Friess, Helmut H; Ceyhan, Güralp Onur GO; Demir, Ihsan Ekin IE

Publication Date: 2020-12-24

Variant appearance in text: CS: G12V

PubMed Link: 33357230

Variant Present in the following documents:

• 13046_2020_Article_1796.pdf

View BVdb publication page

---

Hyperinsulinemic Hypoglycemia in a Patient with Costello Syndrome: An Etiology to Consider in Hypoglycemia.

Molecular Syndromology

Vuralli, Dogus D; Kosukcu, Can C; Taskiran, Ekim E; Simsek-Kiper, Pelin Ozlem PO; Utine, Gulen Eda GE; Boduroglu, Koray K; Alikasifoglu, Ayfer A; Alikasifoglu, Mehmet M

Publication Date: 2020-11

Variant appearance in text: CS: Gly12Val

PubMed Link: 33224014

Variant Present in the following documents:

• Main text

View BVdb publication page

---

SHP2 mutations induce precocious gliogenesis of Noonan syndrome-derived iPSCs during neural development in vitro.

Stem Cell Research & Therapy

Ju, Younghee Y; Park, Jun Sung JS; Kim, Daejeong D; Kim, Bumsoo B; Lee, Jeong Ho JH; Nam, Yoonkey Y; Yoo, Han-Wook HW; Lee, Beom Hee BH; Han, Yong-Mahn YM

Publication Date: 2020-06-03

Variant appearance in text: CS: G12V

PubMed Link: 32493428

Variant Present in the following documents:

• Main text
• 13287_2020_Article_1709.pdf

View BVdb publication page

---

Germline and sporadic cancers driven by the RAS pathway: parallels and contrasts.

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology

Dunnett-Kane, V V; Burkitt-Wright, E E; Blackhall, F H FH; Malliri, A A; Evans, D G DG; Lindsay, C R CR

Publication Date: 2020-07

Variant appearance in text: CS: Gly12Val

PubMed Link: 32240795

Variant Present in the following documents:

• main.pdf

View BVdb publication page

---

The impact of RASopathy-associated mutations on CNS development in mice and humans.

Molecular Brain

Kang, Minkyung M; Lee, Yong-Seok YS

Publication Date: 2019-11-21

Variant appearance in text: CS: G12V

PubMed Link: 31752929

Variant Present in the following documents:

• Main text
• 13041_2019_Article_517.pdf

View BVdb publication page

---

Costello syndrome: Clinical phenotype, genotype, and management guidelines.

American Journal Of Medical Genetics. Part A

Gripp, Karen W KW; Morse, Lindsey A LA; Axelrad, Marni M; Chatfield, Kathryn C KC; Chidekel, Aaron A; Dobyns, William W; Doyle, Daniel D; Kerr, Bronwyn B; Lin, Angela E AE; Schwartz, David D DD; Sibbles, Barbara J BJ; Siegel, Dawn D; Shankar, Suma P SP; Stevenson, David A DA; Thacker, Mihir M MM; Weaver, K Nicole KN; White, Sue M SM; Rauen, Katherine A KA

Publication Date: 2019-09

Variant appearance in text: CS: G12V

PubMed Link: 31222966

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Arid1a restrains Kras-dependent changes in acinar cell identity.

Elife

Livshits, Geulah G; Alonso-Curbelo, Direna D; Morris, John P JP; Koche, Richard R; Saborowski, Michael M; Wilkinson, John Erby JE; Lowe, Scott W SW

Publication Date: 2018-07-17

Variant appearance in text: CS: G12V

PubMed Link: 30014851

Variant Present in the following documents:

• elife-35216.pdf

View BVdb publication page

---

AMP kinase promotes glioblastoma bioenergetics and tumour growth.

Nature Cell Biology

Chhipa, Rishi Raj RR; Fan, Qiang Q; Anderson, Jane J; Muraleedharan, Ranjithmenon R; Huang, Yan Y; Ciraolo, Georgianne G; Chen, Xiaoting X; Waclaw, Ronald R; Chow, Lionel M LM; Khuchua, Zaza Z; Kofron, Matthew M; Weirauch, Matthew T MT; Kendler, Ady A; McPherson, Christopher C; Ratner, Nancy N; Nakano, Ichiro I; Dasgupta, Nupur N; Komurov, Kakajan K; Dasgupta, Biplab B

Publication Date: 2018-07

Variant appearance in text: CS: G12V

PubMed Link: 29915361

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination.

Scientific Reports

Acosta, Maria I MI; Urbach, Serge S; Doye, Anne A; Ng, Yuen-Wai YW; Boudeau, Jérôme J; Mettouchi, Amel A; Debant, Anne A; Manser, Edward E; Visvikis, Orane O; Lemichez, Emmanuel E

Publication Date: 2018-01-23

Variant appearance in text: CS: G12V

PubMed Link: 29362425

Variant Present in the following documents:

• Main text
• 41598_2018_Article_19471.pdf

View BVdb publication page

---

Award Winners and Abstracts of the 31st Annual Symposium of The Protein Society, Montreal, Canada, July 24-27, 2017.

Protein Science : A Publication Of The Protein Society

Publication Date: 2017-12

Variant appearance in text: CS: G12V

PubMed Link: 29280217

Variant Present in the following documents:

• Main text

View BVdb publication page

---

MB0 and MBI Are Independent and Distinct Transactivation Domains in MYC that Are Essential for Transformation.

Genes

Zhang, Qin Q; West-Osterfield, Kimberly K; Spears, Erick E; Li, Zhaoliang Z; Panaccione, Alexander A; Hann, Stephen R SR

Publication Date: 2017-05-06

Variant appearance in text: CS: G12V

PubMed Link: 28481271

Variant Present in the following documents:

• Main text
• genes-08-00134.pdf

View BVdb publication page

---

Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma.

Oncotarget

Furuta, Takuya T; Sabit, Hemragul H; Dong, Yu Y; Miyashita, Katsuyoshi K; Kinoshita, Masashi M; Uchiyama, Naoyuki N; Hayashi, Yasuhiko Y; Hayashi, Yutaka Y; Minamoto, Toshinari T; Nakada, Mitsutoshi M

Publication Date: 2017-04-04

Variant appearance in text: CS: G12V

PubMed Link: 28423558

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Phenotypic spectrum of Costello syndrome individuals harboring the rare HRAS mutation p.Gly13Asp.

American Journal Of Medical Genetics. Part A

Bertola, Débora D; Buscarilli, Michelle M; Stabley, Deborah L DL; Baker, Laura L; Doyle, Daniel D; Bartholomew, Dennis W DW; Sol-Church, Katia K; Gripp, Karen W KW

Publication Date: 2017-05

Variant appearance in text: CS: Gly12Val

PubMed Link: 28371260

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Costello Syndrome and Umbilical Ligament Rhabdomyosarcoma in Two Pediatric Patients: Case Reports and Review of the Literature.

Case Reports In Genetics

Sánchez-Montenegro, Carlos C; Vilanova-Sánchez, Alejandra A; Barrena-Delfa, Saturnino S; Tenorio, Jair J; Santos-Simarro, Fernando F; García-Miñaur, Sixto S; Lapunzina, Pablo P; Martínez-Martínez, Leopoldo L

Publication Date: 2017

Variant appearance in text: CS: G12V

PubMed Link: 28203467

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Receptor Signaling Directs Global Recruitment of Pre-existing Transcription Factors to Inducible Elements.

The Yale Journal Of Biology And Medicine

Cockerill, Peter N PN

Publication Date: 2016-12

Variant appearance in text: CS: G12v

PubMed Link: 28018147

Variant Present in the following documents:

• yjbm_89_4_591.pdf

View BVdb publication page

---

Exploring the interactions of the RAS family in the human protein network and their potential implications in RAS-directed therapies.

Oncotarget

Bueno, Anibal A; Morilla, Ian I; Diez, Diego D; Moya-Garcia, Aurelio A AA; Lozano, José J; Ranea, Juan A G JA

Publication Date: 2016-11-15

Variant appearance in text: CS: G12V

PubMed Link: 27713118

Variant Present in the following documents:

• oncotarget-07-75810-s002.xlsx, sheet 11
• oncotarget-07-75810-s002.xlsx, sheet 7

View BVdb publication page

---

Modeling craniofacial and skeletal congenital birth defects to advance therapies.

Human Molecular Genetics

Neben, Cynthia L CL; Roberts, Ryan R RR; Dipple, Katrina M KM; Merrill, Amy E AE; Klein, Ophir D OD

Publication Date: 2016-10-01

Variant appearance in text: CS: G12V

PubMed Link: 27346519

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Xpg limits the expansion of haematopoietic stem and progenitor cells after ionising radiation.

Nucleic Acids Research

Avila, Alush I AI; Illing, Anett A; Becker, Friedrich F; Maerz, Lars D LD; Morita, Yohei Y; Philipp, Melanie M; Burkhalter, Martin D MD

Publication Date: 2016-07-27

Variant appearance in text: CS: G12V

PubMed Link: 27137888

Variant Present in the following documents:

• Main text
• gkw376.pdf

View BVdb publication page

---

Respiratory system involvement in Costello syndrome.

American Journal Of Medical Genetics. Part A

Gomez-Ospina, Natalia N; Kuo, Christin C; Ananth, Amitha Lakshmi AL; Myers, Angela A; Brennan, Marie-Luise ML; Stevenson, David A DA; Bernstein, Jonathan A JA; Hudgins, Louanne L

Publication Date: 2016-07

Variant appearance in text: CS: G12V

PubMed Link: 27102959

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure induce strong immune responses and display therapeutic effects both in murine TC-1 and TRAMP-C2 tumors when combined with docetaxel chemotherapy.

International Journal Of Oncology

Mikyšková, Romana R; Štěpánek, Ivan I; Indrová, Marie M; Bieblová, Jana J; Šímová, Jana J; Truxová, Iva I; Moserová, Irena I; Fučíková, Jitka J; Bartůňková, Jiřina J; Špíšek, Radek R; Reiniš, Milan M

Publication Date: 2016-03

Variant appearance in text: CS: G12V

PubMed Link: 26718011

Variant Present in the following documents:

• ijo-48-03-0953.pdf

View BVdb publication page

---

The impact of the genetic background in the Noonan syndrome phenotype induced by K-Ras(V14I).

Rare Diseases (Austin, Tex.)

Hernández-Porras, Isabel I; Jiménez-Catalán, Beatriz B; Schuhmacher, Alberto J AJ; Guerra, Carmen C

Publication Date: 2015

Variant appearance in text: CS: G12V

PubMed Link: 26458870

Variant Present in the following documents:

• Main text

View BVdb publication page

---

In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome.

Frontiers In Cellular Neuroscience

Wang, Tiantian T; de Kok, Laura L; Willemsen, Rob R; Elgersma, Ype Y; Borst, J Gerard G JG

Publication Date: 2015

Variant appearance in text: CS: G12V

PubMed Link: 26190969

Variant Present in the following documents:

• Main text

View BVdb publication page

---

The role of p19 and p21 H-Ras proteins and mutants in miRNA expression in cancer and a Costello syndrome cell model.

Bmc Medical Genetics

García-Cruz, Roseli R; Camats, Maria M; Calin, George A GA; Liu, Chang-Gong CG; Volinia, Stefano S; Taccioli, Cristian C; Croce, Carlo M CM; Bach-Elias, Montse M

Publication Date: 2015-07-03

Variant appearance in text: CS: G12V

PubMed Link: 26138095

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Dissecting Genomic Aberrations in Myeloproliferative Neoplasms by Multiplex-PCR and Next Generation Sequencing.

Plos One

Kirschner, Martin M J MM; Schemionek, Mirle M; Schubert, Claudia C; Chatain, Nicolas N; Sontag, Stephanie S; Isfort, Susanne S; Ortiz-Brüchle, Nadina N; Schmitt, Karla K; Krüger, Luisa L; Zerres, Klaus K; Zenke, Martin M; Brümmendorf, Tim H TH; Koschmieder, Steffen S

Publication Date: 2015

Variant appearance in text: CS: 35G>T; G12V

PubMed Link: 25894969

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Integrative analysis of haplotype-resolved epigenomes across human tissues.

Nature

Leung, Danny D; Jung, Inkyung I; Rajagopal, Nisha N; Schmitt, Anthony A; Selvaraj, Siddarth S; Lee, Ah Young AY; Yen, Chia-An CA; Lin, Shin S; Lin, Yiing Y; Qiu, Yunjiang Y; Xie, Wei W; Yue, Feng F; Hariharan, Manoj M; Ray, Pradipta P; Kuan, Samantha S; Edsall, Lee L; Yang, Hongbo H; Chi, Neil C NC; Zhang, Michael Q MQ; Ecker, Joseph R JR; Ren, Bing B

Publication Date: 2015-02-19

Variant appearance in text: CS: G12V

PubMed Link: 25693566

Variant Present in the following documents:

• nihms-654062.pdf

View BVdb publication page

---

miRNA-130b is required for the ERK/FOXM1 pathway activation-mediated protective effects of isosorbide dinitrate against mesenchymal stem cell senescence induced by high glucose.

International Journal Of Molecular Medicine

Xu, Jianfeng J; Huang, Zheyong Z; Lin, Li L; Fu, Mingqiang M; Song, Yanan Y; Shen, Yunli Y; Ren, Daoyuan D; Gao, Yanhua Y; Su, Yangang Y; Zou, Yunzeng Y; Chen, Yueguang Y; Zhang, Dadong D; Hu, Wei W; Qian, Juying J; Ge, Junbo J

Publication Date: 2015-01

Variant appearance in text: CS: G12V

PubMed Link: 25355277

Variant Present in the following documents:

• ijmm-35-01-0059.pdf

View BVdb publication page

---

Ras-mediated deregulation of the circadian clock in cancer.

Plos Genetics

Relógio, Angela A; Thomas, Philippe P; Medina-Pérez, Paula P; Reischl, Silke S; Bervoets, Sander S; Gloc, Ewa E; Riemer, Pamela P; Mang-Fatehi, Shila S; Maier, Bert B; Schäfer, Reinhold R; Leser, Ulf U; Herzel, Hanspeter H; Kramer, Achim A; Sers, Christine C

Publication Date: 2014

Variant appearance in text: CS: G12V

PubMed Link: 24875049

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A novel mechanism by which tissue transglutaminase activates signaling events that promote cell survival.

The Journal Of Biological Chemistry

Boroughs, Lindsey K LK; Antonyak, Marc A MA; Cerione, Richard A RA

Publication Date: 2014-04-04

Variant appearance in text: CS: G12V

PubMed Link: 24569994

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Tumor glycolysis as a target for cancer therapy: progress and prospects.

Molecular Cancer

Ganapathy-Kanniappan, Shanmugasundaram S; Geschwind, Jean-Francois H JF

Publication Date: 2013-12-03

Variant appearance in text: CS: G12V

PubMed Link: 24298908

Variant Present in the following documents:

• 1476-4598-12-152.pdf

View BVdb publication page

---

Contributions of intrinsic mutation rate and selfish selection to levels of de novo HRAS mutations in the paternal germline.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Giannoulatou, Eleni E; McVean, Gilean G; Taylor, Indira B IB; McGowan, Simon J SJ; Maher, Geoffrey J GJ; Iqbal, Zamin Z; Pfeifer, Susanne P SP; Turner, Isaac I; Burkitt Wright, Emma M M EM; Shorto, Jennifer J; Itani, Aysha A; Turner, Karen K; Gregory, Lorna L; Buck, David D; Rajpert-De Meyts, Ewa E; Looijenga, Leendert H J LH; Kerr, Bronwyn B; Wilkie, Andrew O M AO; Goriely, Anne A

Publication Date: 2013-12-10

Variant appearance in text: CS: 35G>T

PubMed Link: 24259709

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Lymphatic vessel abnormalities arising from disorders of Ras signal transduction.

Trends In Cardiovascular Medicine

Sevick-Muraca, Eva M EM; King, Philip D PD

Publication Date: 2014-04

Variant appearance in text: CS: G12V

PubMed Link: 24183794

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Abnormal Ras signaling in Costello syndrome (CS) negatively regulates enamel formation.

Human Molecular Genetics

Goodwin, Alice F AF; Tidyman, William E WE; Jheon, Andrew H AH; Sharir, Amnon A; Zheng, Xu X; Charles, Cyril C; Fagin, James A JA; McMahon, Martin M; Diekwisch, Thomas G H TG; Ganss, Bernhard B; Rauen, Katherine A KA; Klein, Ophir D OD

Publication Date: 2014-02-01

Variant appearance in text: CS: G12V

PubMed Link: 24057668

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesis.

Cancer Research

Arendt, Lisa M LM; McCready, Jessica J; Keller, Patricia J PJ; Baker, Dana D DD; Naber, Stephen P SP; Seewaldt, Victoria V; Kuperwasser, Charlotte C

Publication Date: 2013-10-01

Variant appearance in text: CS: G12V

PubMed Link: 23959857

Variant Present in the following documents:

• Main text

View BVdb publication page

---

RIP1 potentiates BPDE-induced transformation in human bronchial epithelial cells through catalase-mediated suppression of excessive reactive oxygen species.

Carcinogenesis

Wang, Qiong Q; Chen, Wenshu W; Xu, Xiuling X; Li, Bilan B; He, Weiyang W; Padilla, Mabel T MT; Jang, Jun-Ho JH; Nyunoya, Toru T; Amin, Shantu S; Wang, Xia X; Lin, Yong Y

Publication Date: 2013-09

Variant appearance in text: CS: G12V

PubMed Link: 23633517

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Cross-complementation study of the flagellar type III export apparatus membrane protein FlhB.

Plos One

Barker, Clive S CS; Samatey, Fadel A FA

Publication Date: 2012

Variant appearance in text: CS: Gly12Val

PubMed Link: 22952860

Variant Present in the following documents:

• pone.0044030.pdf

View BVdb publication page

---

Glycosaminoglycan-dependent restriction of FGF diffusion is necessary for lacrimal gland development.

Development (Cambridge, England)

Qu, Xiuxia X; Pan, Yi Y; Carbe, Christian C; Powers, Andrea A; Grobe, Kay K; Zhang, Xin X

Publication Date: 2012-08

Variant appearance in text: CS: G12V

PubMed Link: 22745308

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Group I and II mammalian PAKs have different modes of activation by Cdc42.

Embo Reports

Baskaran, Yohendran Y; Ng, Yuen-Wai YW; Selamat, Widyawilis W; Ling, Felicia Tay Pei FT; Manser, Ed E

Publication Date: 2012-06-29

Variant appearance in text: CS: G12V

PubMed Link: 22653441

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A SUMOylation Motif in Aurora-A: Implications for Spindle Dynamics and Oncogenesis.

Frontiers In Oncology

Pérez de Castro, Ignacio I; Aguirre-Portolés, Cristina C; Martin, Benedicte B; Fernández-Miranda, Gonzalo G; Klotzbucher, Andrea A; Kubbutat, Michael H G MH; Megías, Diego D; Arlot-Bonnemains, Yannick Y; Malumbres, Marcos M

Publication Date: 2011

Variant appearance in text: CS: G12V

PubMed Link: 22649767

Variant Present in the following documents:

• Main text

View BVdb publication page

---

PEA-15 potentiates H-Ras-mediated epithelial cell transformation through phospholipase D.

Oncogene

Sulzmaier, F J FJ; Valmiki, M K G MK; Nelson, D A DA; Caliva, M J MJ; Geerts, D D; Matter, M L ML; White, E P EP; Ramos, J W JW

Publication Date: 2012-07-26

Variant appearance in text: CS: G12V

PubMed Link: 22105357

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Effects of integrin-mediated cell adhesion on plasma membrane lipid raft components and signaling.

Molecular Biology Of The Cell

Norambuena, Andrés A; Schwartz, Martin A MA

Publication Date: 2011-09

Variant appearance in text: CS: G12V

PubMed Link: 21795400

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Ras in cancer and developmental diseases.

Genes & Cancer

Fernández-Medarde, Alberto A; Santos, Eugenio E

Publication Date: 2011-03

Variant appearance in text: CS: G12V

PubMed Link: 21779504

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines.

Nature

Murakoshi, Hideji H; Wang, Hong H; Yasuda, Ryohei R

Publication Date: 2011-04-07

Variant appearance in text: CS: G12V

PubMed Link: 21423166

Variant Present in the following documents:

• nihms264522.pdf

View BVdb publication page

---

MEK-ERK pathway modulation ameliorates disease phenotypes in a mouse model of Noonan syndrome associated with the Raf1(L613V) mutation.

The Journal Of Clinical Investigation

Wu, Xue X; Simpson, Jeremy J; Hong, Jenny H JH; Kim, Kyoung-Han KH; Thavarajah, Nirusha K NK; Backx, Peter H PH; Neel, Benjamin G BG; Araki, Toshiyuki T

Publication Date: 2011-03

Variant appearance in text: CS: G12V

PubMed Link: 21339642

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Phosphorylation of Lte1 by Cdk prevents polarized growth during mitotic arrest in S. cerevisiae.

The Journal Of Cell Biology

Geymonat, Marco M; Spanos, Adonis A; Jensen, Sanne S; Sedgwick, Steven G SG

Publication Date: 2010-12-13

Variant appearance in text: CS: G12V

PubMed Link: 21149565

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Enhanced human brain associative plasticity in Costello syndrome.

The Journal Of Physiology

Dileone, M M; Profice, P P; Pilato, F F; Alfieri, P P; Cesarini, L L; Mercuri, E E; Leoni, C C; Tartaglia, M M; Di Iorio, R R; Zampino, G G; Di Lazzaro, V V

Publication Date: 2010-09-15

Variant appearance in text: CS: G12V

PubMed Link: 20660566

Variant Present in the following documents:

• Main text

View BVdb publication page

---

KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA.

The Journal Of Biological Chemistry

Tago, Kenji K; Funakoshi-Tago, Megumi M; Sakinawa, Masaki M; Mizuno, Norikazu N; Itoh, Hiroshi H

Publication Date: 2010-10-01

Variant appearance in text: CS: G12V

PubMed Link: 20639196

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Corticosteroids: way upstream.

Molecular Brain

Riedemann, Therese T; Patchev, Alexandre V AV; Cho, Kwangwook K; Almeida, Osborne F X OF

Publication Date: 2010-01-11

Variant appearance in text: CS: G12V

PubMed Link: 20180948

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Activated Ras alters lens and corneal development through induction of distinct downstream targets.

Bmc Developmental Biology

Burgess, Daniel D; Zhang, Yan Y; Siefker, Ed E; Vaca, Ryan R; Kuracha, Murali R MR; Reneker, Lixing L; Overbeek, Paul A PA; Govindarajan, Venkatesh V

Publication Date: 2010-01-27

Variant appearance in text: CS: G12V

PubMed Link: 20105280

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Modelling oncogenic Ras/Raf signalling in the mouse.

Current Opinion In Genetics & Development

Karreth, Florian A FA; Tuveson, David A DA

Publication Date: 2009-02

Variant appearance in text: CS: G12V

PubMed Link: 19201597

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Kank attenuates actin remodeling by preventing interaction between IRSp53 and Rac1.

The Journal Of Cell Biology

Roy, Badal Chandra BC; Kakinuma, Naoto N; Kiyama, Ryoiti R

Publication Date: 2009-01-26

Variant appearance in text: CS: G12V

PubMed Link: 19171758

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition.

The Journal Of Clinical Investigation

Schuhmacher, Alberto J AJ; Guerra, Carmen C; Sauzeau, Vincent V; Cañamero, Marta M; Bustelo, Xosé R XR; Barbacid, Mariano M

Publication Date: 2008-06

Variant appearance in text: CS: Gly12Val

PubMed Link: 18483625

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Common activation of canonical Wnt signaling in pancreatic adenocarcinoma.

Plos One

Pasca di Magliano, Marina M; Biankin, Andrew V AV; Heiser, Patrick W PW; Cano, David A DA; Gutierrez, Pedro J A PJ; Deramaudt, Therese T; Segara, Davendra D; Dawson, Amanda C AC; Kench, James G JG; Henshall, Susan M SM; Sutherland, Robert L RL; Dlugosz, Andrzej A; Rustgi, Anil K AK; Hebrok, Matthias M

Publication Date: 2007-11-07

Variant appearance in text: CS: G12V

PubMed Link: 17982507

Variant Present in the following documents:

• pone.0001155.pdf

View BVdb publication page

---

Myopathy caused by HRAS germline mutations: implications for disturbed myogenic differentiation in the presence of constitutive HRas activation.

Journal Of Medical Genetics

van der Burgt, Ineke I; Kupsky, William W; Stassou, Stephani S; Nadroo, Ali A; Barroso, Cândida C; Diem, Angelika A; Kratz, Christian P CP; Dvorsky, Radovan R; Ahmadian, Mohammad Reza MR; Zenker, Martin M

Publication Date: 2007-07

Variant appearance in text: CS: G12V

PubMed Link: 17412879

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Focal adhesion kinase mediates the integrin signaling requirement for growth factor activation of MAP kinase.

The Journal Of Cell Biology

Renshaw, M W MW; Price, L S LS; Schwartz, M A MA

Publication Date: 1999-11-01

Variant appearance in text: CS: G12V

PubMed Link: 10545504

Variant Present in the following documents:

• 9901031.pdf

View BVdb publication page

---