Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids.
Oncotarget
Devall, Matthew M; Dampier, Christopher H CH; Eaton, Stephen S; Ali, Mourad W MW; Díez-Obrero, Virginia V; Moratalla-Navarro, Ferran F; Bryant, Jennifer J; Jennelle, Lucas T LT; Moreno, Victor V; Powell, Steven M SM; Peters, Ulrike U; Casey, Graham G
Effects of common genetic variants associated with colorectal cancer risk on survival outcomes after diagnosis: A large population-based cohort study.
International Journal Of Cancer
He, Yazhou Y; Theodoratou, Evropi E; Li, Xue X; Din, Farhat V N FVN; Vaughan-Shaw, Peter P; Svinti, Victoria V; Farrington, Susan M SM; Campbell, Harry H; Dunlop, Malcolm G MG; Timofeeva, Maria M
Discovery of common and rare genetic risk variants for colorectal cancer.
Nature Genetics
Huyghe, Jeroen R JR; Bien, Stephanie A SA; Harrison, Tabitha A TA; Kang, Hyun Min HM; Chen, Sai S; Schmit, Stephanie L SL; Conti, David V DV; Qu, Conghui C; Jeon, Jihyoun J; Edlund, Christopher K CK; Greenside, Peyton P; Wainberg, Michael M; Schumacher, Fredrick R FR; Smith, Joshua D JD; Levine, David M DM; Nelson, Sarah C SC; Sinnott-Armstrong, Nasa A NA; Albanes, Demetrius D; Alonso, M Henar MH; Anderson, Kristin K; Arnau-Collell, Coral C; Arndt, Volker V; Bamia, Christina C; Banbury, Barbara L BL; Baron, John A JA; Berndt, Sonja I SI; Bézieau, Stéphane S; Bishop, D Timothy DT; Boehm, Juergen J; Boeing, Heiner H; Brenner, Hermann H; Brezina, Stefanie S; Buch, Stephan S; Buchanan, Daniel D DD; Burnett-Hartman, Andrea A; Butterbach, Katja K; Caan, Bette J BJ; Campbell, Peter T PT; Carlson, Christopher S CS; Castellví-Bel, Sergi S; Chan, Andrew T AT; Chang-Claude, Jenny J; Chanock, Stephen J SJ; Chirlaque, Maria-Dolores MD; Cho, Sang Hee SH; Connolly, Charles M CM; Cross, Amanda J AJ; Cuk, Katarina K; Curtis, Keith R KR; de la Chapelle, Albert A; Doheny, Kimberly F KF; Duggan, David D; Easton, Douglas F DF; Elias, Sjoerd G SG; Elliott, Faye F; English, Dallas R DR; Feskens, Edith J M EJM; Figueiredo, Jane C JC; Fischer, Rocky R; FitzGerald, Liesel M LM; Forman, David D; Gala, Manish M; Gallinger, Steven S; Gauderman, W James WJ; Giles, Graham G GG; Gillanders, Elizabeth E; Gong, Jian J; Goodman, Phyllis J PJ; Grady, William M WM; Grove, John S JS; Gsur, Andrea A; Gunter, Marc J MJ; Haile, Robert W RW; Hampe, Jochen J; Hampel, Heather H; Harlid, Sophia S; Hayes, Richard B RB; Hofer, Philipp P; Hoffmeister, Michael M; Hopper, John L JL; Hsu, Wan-Ling WL; Huang, Wen-Yi WY; Hudson, Thomas J TJ; Hunter, David J DJ; Ibañez-Sanz, Gemma G; Idos, Gregory E GE; Ingersoll, Roxann R; Jackson, Rebecca D RD; Jacobs, Eric J EJ; Jenkins, Mark A MA; Joshi, Amit D AD; Joshu, Corinne E CE; Keku, Temitope O TO; Key, Timothy J TJ; Kim, Hyeong Rok HR; Kobayashi, Emiko E; Kolonel, Laurence N LN; Kooperberg, Charles C; Kühn, Tilman T; Küry, Sébastien S; Kweon, Sun-Seog SS; Larsson, Susanna C SC; Laurie, Cecelia A CA; Le Marchand, Loic L; Leal, Suzanne M SM; Lee, Soo Chin SC; Lejbkowicz, Flavio F; Lemire, Mathieu M; Li, Christopher I CI; Li, Li L; Lieb, Wolfgang W; Lin, Yi Y; Lindblom, Annika A; Lindor, Noralane M NM; Ling, Hua H; Louie, Tin L TL; Männistö, Satu S; Markowitz, Sanford D SD; Martín, Vicente V; Masala, Giovanna G; McNeil, Caroline E CE; Melas, Marilena M; Milne, Roger L RL; Moreno, Lorena L; Murphy, Neil N; Myte, Robin R; Naccarati, Alessio A; Newcomb, Polly A PA; Offit, Kenneth K; Ogino, Shuji S; Onland-Moret, N Charlotte NC; Pardini, Barbara B; Parfrey, Patrick S PS; Pearlman, Rachel R; Perduca, Vittorio V; Pharoah, Paul D P PDP; Pinchev, Mila M; Platz, Elizabeth A EA; Prentice, Ross L RL; Pugh, Elizabeth E; Raskin, Leon L; Rennert, Gad G; Rennert, Hedy S HS; Riboli, Elio E; Rodríguez-Barranco, Miguel M; Romm, Jane J; Sakoda, Lori C LC; Schafmayer, Clemens C; Schoen, Robert E RE; Seminara, Daniela D; Shah, Mitul M; Shelford, Tameka T; Shin, Min-Ho MH; Shulman, Katerina K; Sieri, Sabina S; Slattery, Martha L ML; Southey, Melissa C MC; Stadler, Zsofia K ZK; Stegmaier, Christa C; Su, Yu-Ru YR; Tangen, Catherine M CM; Thibodeau, Stephen N SN; Thomas, Duncan C DC; Thomas, Sushma S SS; Toland, Amanda E AE; Trichopoulou, Antonia A; Ulrich, Cornelia M CM; Van Den Berg, David J DJ; van Duijnhoven, Franzel J B FJB; Van Guelpen, Bethany B; van Kranen, Henk H; Vijai, Joseph J; Visvanathan, Kala K; Vodicka, Pavel P; Vodickova, Ludmila L; Vymetalkova, Veronika V; Weigl, Korbinian K; Weinstein, Stephanie J SJ; White, Emily E; Win, Aung Ko AK; Wolf, C Roland CR; Wolk, Alicja A; Woods, Michael O MO; Wu, Anna H AH; Zaidi, Syed H SH; Zanke, Brent W BW; Zhang, Qing Q; Zheng, Wei W; Scacheri, Peter C PC; Potter, John D JD; Bassik, Michael C MC; Kundaje, Anshul A; Casey, Graham G; Moreno, Victor V; Abecasis, Goncalo R GR; Nickerson, Deborah A DA; Gruber, Stephen B SB; Hsu, Li L; Peters, Ulrike U
Genome-wide meta-analysis identifies new susceptibility loci for migraine.
Nature Genetics
Anttila, Verneri V; Winsvold, Bendik S BS; Gormley, Padhraig P; Kurth, Tobias T; Bettella, Francesco F; McMahon, George G; Kallela, Mikko M; Malik, Rainer R; de Vries, Boukje B; Terwindt, Gisela G; Medland, Sarah E SE; Todt, Unda U; McArdle, Wendy L WL; Quaye, Lydia L; Koiranen, Markku M; Ikram, M Arfan MA; Lehtimäki, Terho T; Stam, Anine H AH; Ligthart, Lannie L; Wedenoja, Juho J; Dunham, Ian I; Neale, Benjamin M BM; Palta, Priit P; Hamalainen, Eija E; Schürks, Markus M; Rose, Lynda M LM; Buring, Julie E JE; Ridker, Paul M PM; Steinberg, Stacy S; Stefansson, Hreinn H; Jakobsson, Finnbogi F; Lawlor, Debbie A DA; Evans, David M DM; Ring, Susan M SM; Färkkilä, Markus M; Artto, Ville V; Kaunisto, Mari A MA; Freilinger, Tobias T; Schoenen, Jean J; Frants, Rune R RR; Pelzer, Nadine N; Weller, Claudia M CM; Zielman, Ronald R; Heath, Andrew C AC; Madden, Pamela A F PAF; Montgomery, Grant W GW; Martin, Nicholas G NG; Borck, Guntram G; Göbel, Hartmut H; Heinze, Axel A; Heinze-Kuhn, Katja K; Williams, Frances M K FMK; Hartikainen, Anna-Liisa AL; Pouta, Anneli A; van den Ende, Joyce J; Uitterlinden, Andre G AG; Hofman, Albert A; Amin, Najaf N; Hottenga, Jouke-Jan JJ; Vink, Jacqueline M JM; Heikkilä, Kauko K; Alexander, Michael M; Muller-Myhsok, Bertram B; Schreiber, Stefan S; Meitinger, Thomas T; Wichmann, Heinz Erich HE; Aromaa, Arpo A; Eriksson, Johan G JG; Traynor, Bryan B; Trabzuni, Daniah D; , ; , ; Rossin, Elizabeth E; Lage, Kasper K; Jacobs, Suzanne B R SBR; Gibbs, J Raphael JR; Birney, Ewan E; Kaprio, Jaakko J; Penninx, Brenda W BW; Boomsma, Dorret I DI; van Duijn, Cornelia C; Raitakari, Olli O; Jarvelin, Marjo-Riitta MR; Zwart, John-Anker JA; Cherkas, Lynn L; Strachan, David P DP; Kubisch, Christian C; Ferrari, Michel D MD; van den Maagdenberg, Arn M J M AMJM; Dichgans, Martin M; Wessman, Maija M; Smith, George Davey GD; Stefansson, Kari K; Daly, Mark J MJ; Nyholt, Dale R DR; Chasman, Daniel D; Palotie, Aarno A
Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies.
International Journal Of Obesity (2005)
Smith, C E CE; Ngwa, J J; Tanaka, T T; Qi, Q Q; Wojczynski, M K MK; Lemaitre, R N RN; Anderson, J S JS; Manichaikul, A A; Mikkilä, V V; van Rooij, F J A FJ; Ye, Z Z; Bandinelli, S S; Frazier-Wood, A C AC; Houston, D K DK; Hu, F F; Langenberg, C C; McKeown, N M NM; Mozaffarian, D D; North, K E KE; Viikari, J J; Zillikens, M C MC; Djoussé, L L; Hofman, A A; Kähönen, M M; Kabagambe, E K EK; Loos, R J F RJ; Saylor, G B GB; Forouhi, N G NG; Liu, Y Y; Mukamal, K J KJ; Chen, Y-D I YD; Tsai, M Y MY; Uitterlinden, A G AG; Raitakari, O O; van Duijn, C M CM; Arnett, D K DK; Borecki, I B IB; Cupples, L A LA; Ferrucci, L L; Kritchevsky, S B SB; Lehtimäki, T T; Qi, Lu L; Rotter, J I JI; Siscovick, D S DS; Wareham, N J NJ; Witteman, J C M JC; Ordovás, J M JM; Nettleton, J A JA
LRP-1 variation is not associated with risk of Alzheimer's disease.
International Journal Of Molecular Epidemiology And Genetics
Chalmers, Katy A KA; Barker, Rachel R; Passmore, Peter A PA; Panza, Francesco F; Seripa, Davide D; Solfrizzi, Vincenzo V; Love, Seth S; Prince, Jonathan A JA; Kehoe, Patrick G PG
Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus.
Plos Genetics
Weidinger, Stephan S; Gieger, Christian C; Rodriguez, Elke E; Baurecht, Hansjörg H; Mempel, Martin M; Klopp, Norman N; Gohlke, Henning H; Wagenpfeil, Stefan S; Ollert, Markus M; Ring, Johannes J; Behrendt, Heidrun H; Heinrich, Joachim J; Novak, Natalija N; Bieber, Thomas T; Krämer, Ursula U; Berdel, Dietrich D; von Berg, Andrea A; Bauer, Carl Peter CP; Herbarth, Olf O; Koletzko, Sibylle S; Prokisch, Holger H; Mehta, Divya D; Meitinger, Thomas T; Depner, Martin M; von Mutius, Erika E; Liang, Liming L; Moffatt, Miriam M; Cookson, William W; Kabesch, Michael M; Wichmann, H-Erich HE; Illig, Thomas T