Mucosal HPV E6/E7 Peptide Vaccination in Combination with Immune Checkpoint Modulation Induces Regression of HPV+ Oral Cancers.
Cancer Research
Dorta-Estremera, Stephanie S; Chin, Renee L RL; Sierra, Gloria G; Nicholas, Courtney C; Yanamandra, Ananta V AV; Nookala, Sita M K SMK; Yang, Guojun G; Singh, Shail S; Curran, Michael A MA; Sastry, K Jagannadha KJ
Mitigating SOX2-potentiated Immune Escape of Head and Neck Squamous Cell Carcinoma with a STING-inducing Nanosatellite Vaccine.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Tan, Yee Sun YS; Sansanaphongpricha, Kanokwan K; Xie, Yuying Y; Donnelly, Christopher R CR; Luo, Xiaobo X; Heath, Blake R BR; Zhao, Xinyi X; Bellile, Emily E; Hu, Hongxiang H; Chen, Hongwei H; Polverini, Peter J PJ; Chen, Qianming Q; Young, Simon S; Carey, Thomas E TE; Nör, Jacques E JE; Ferris, Robert L RL; Wolf, Gregory T GT; Sun, Duxin D; Lei, Yu L YL
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV+ tumors when combined with an E6/E7 peptide vaccine.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Bartkowiak, Todd T; Singh, Shailbala S; Yang, Guojun G; Galvan, Gloria G; Haria, Dhwani D; Ai, Midan M; Allison, James P JP; Sastry, K Jagannadha KJ; Curran, Michael A MA
Intranasal immunization with synthetic peptides corresponding to the E6 and E7 oncoproteins of human papillomavirus type 16 induces systemic and mucosal cellular immune responses and tumor protection.
Vaccine
Manuri, Pallavi R PR; Nehete, Bharti B; Nehete, Pramod N PN; Reisenauer, Rose R; Wardell, Seth S; Courtney, Amy N AN; Gambhira, Ratish R; Lomada, Dakshyani D; Chopra, Ashok K AK; Sastry, K Jagannadha KJ