CD4 c.780A>T ;(p.E260D)

Variant ID: 12-6925394-A-T

NM_000616.4(CD4):c.780A>T;(p.E260D)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Differential Immunodominance Hierarchy of CD8+ T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection.

Journal Of Virology
Adland, Emily E; Hill, Matilda M; Lavandier, Nora N; Csala, Anna A; Edwards, Anne A; Chen, Fabian F; Radkowski, Marek M; Kowalska, Justyna D JD; Paraskevis, Dimitrios D; Hatzakis, Angelos A; Valenzuela-Ponce, Humberto H; Pfafferott, Katja K; Williams, Ian I; Pellegrino, Pierre P; Borrow, Persephone P; Mori, Masahiko M; Rockstroh, Jürgen J; Prado, Julia G JG; Mothe, Beatriz B; Dalmau, Judith J; Martinez-Picado, Javier J; Tudor-Williams, Gareth G; Frater, John J; Stryhn, Anette A; Buus, Soren S; Teran, Gustavo Reyes GR; Mallal, Simon S; John, Mina M; Buchbinder, Susan S; Kirk, Gregory G; Martin, Jeffrey J; Michael, Nelson N; Fellay, Jacques J; Deeks, Steve S; Walker, Bruce B; Avila-Rios, Santiago S; Cole, David D; Brander, Christian C; Carrington, Mary M; Goulder, Philip P
Publication Date: 2018-02-15

Variant appearance in text: CD4: E260D
PubMed Link: 29167337
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pressure from TRIM5α contributes to control of HIV-1 replication by individuals expressing protective HLA-B alleles.

Journal Of Virology
Granier, Clémence C; Battivelli, Emilie E; Lécuroux, Camille C; Venet, Alain A; Lambotte, Olivier O; Schmitt-Boulanger, Marion M; Delaugerre, Constance C; Molina, Jean-Michel JM; Chakrabarti, Lisa A LA; Clavel, François F; Hance, Allan J AJ
Publication Date: 2013-09

Variant appearance in text: CD4: E260D
PubMed Link: 23864638
Variant Present in the following documents:
  • Main text
View BVdb publication page



Differential clade-specific HLA-B*3501 association with HIV-1 disease outcome is linked to immunogenicity of a single Gag epitope.

Journal Of Virology
Matthews, Philippa C PC; Koyanagi, Madoka M; Kløverpris, Henrik N HN; Harndahl, Mikkel M; Stryhn, Anette A; Akahoshi, Tomohiro T; Gatanaga, Hiroyuki H; Oka, Shinichi S; Juarez Molina, Claudia C; Valenzuela Ponce, Humberto H; Avila Rios, Santiago S; Cole, David D; Carlson, Jonathan J; Payne, Rebecca P RP; Ogwu, Anthony A; Bere, Alfred A; Ndung'u, Thumbi T; Gounder, Kamini K; Chen, Fabian F; Riddell, Lynn L; Luzzi, Graz G; Shapiro, Roger R; Brander, Christian C; Walker, Bruce B; Sewell, Andrew K AK; Reyes Teran, Gustavo G; Heckerman, David D; Hunter, Eric E; Buus, Søren S; Takiguchi, Masafumi M; Goulder, Philip J R PJ
Publication Date: 2012-12

Variant appearance in text: CD4: E260D
PubMed Link: 22973023
Variant Present in the following documents:
  • Main text
View BVdb publication page



Gag cytotoxic T lymphocyte escape mutations can increase sensitivity of HIV-1 to human TRIM5alpha, linking intrinsic and acquired immunity.

Journal Of Virology
Battivelli, Emilie E; Migraine, Julie J; Lecossier, Denise D; Yeni, Patrick P; Clavel, François F; Hance, Allan J AJ
Publication Date: 2011-11

Variant appearance in text: CD4: E260D
PubMed Link: 21917976
Variant Present in the following documents:
  • Main text
View BVdb publication page



Early selection in Gag by protective HLA alleles contributes to reduced HIV-1 replication capacity that may be largely compensated for in chronic infection.

Journal Of Virology
Brockman, Mark A MA; Brumme, Zabrina L ZL; Brumme, Chanson J CJ; Miura, Toshiyuki T; Sela, Jennifer J; Rosato, Pamela C PC; Kadie, Carl M CM; Carlson, Jonathan M JM; Markle, Tristan J TJ; Streeck, Hendrik H; Kelleher, Anthony D AD; Markowitz, Martin M; Jessen, Heiko H; Rosenberg, Eric E; Altfeld, Marcus M; Harrigan, P Richard PR; Heckerman, David D; Walker, Bruce D BD; Allen, Todd M TM
Publication Date: 2010-11

Variant appearance in text: CD4: E260D
PubMed Link: 20810731
Variant Present in the following documents:
  • Main text
View BVdb publication page



Structural and functional constraints limit options for cytotoxic T-lymphocyte escape in the immunodominant HLA-B27-restricted epitope in human immunodeficiency virus type 1 capsid.

Journal Of Virology
Schneidewind, Arne A; Brockman, Mark A MA; Sidney, John J; Wang, Yaoyu E YE; Chen, Huabiao H; Suscovich, Todd J TJ; Li, Bin B; Adam, Rahma I RI; Allgaier, Rachel L RL; Mothé, Bianca R BR; Kuntzen, Thomas T; Oniangue-Ndza, Cesar C; Trocha, Alicja A; Yu, Xu G XG; Brander, Christian C; Sette, Alessandro A; Walker, Bruce D BD; Allen, Todd M TM
Publication Date: 2008-06

Variant appearance in text: CD4: E260D
PubMed Link: 18385228
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clustered mutations in HIV-1 gag are consistently required for escape from HLA-B27-restricted cytotoxic T lymphocyte responses.

The Journal Of Experimental Medicine
Kelleher, A D AD; Long, C C; Holmes, E C EC; Allen, R L RL; Wilson, J J; Conlon, C C; Workman, C C; Shaunak, S S; Olson, K K; Goulder, P P; Brander, C C; Ogg, G G; Sullivan, J S JS; Dyer, W W; Jones, I I; McMichael, A J AJ; Rowland-Jones, S S; Phillips, R E RE
Publication Date: 2001-02-05

Variant appearance in text: CD4: E260D
PubMed Link: 11157057
Variant Present in the following documents:
  • Main text
  • 000111.pdf
View BVdb publication page