CD4 c.958_959delinsCT ;(p.T320L)

Variant ID: 12-6926298-AC-CT

NM_000616.4(CD4):c.958_959delinsCT;(p.T320L)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Structure-guided envelope trimer design in HIV-1 vaccine development: a narrative review.

Journal Of The International Aids Society
Derking, Ronald R; Sanders, Rogier W RW
Publication Date: 2021-11

Variant appearance in text: CD4: T320L
PubMed Link: 34806305
Variant Present in the following documents:
  • Main text
  • JIA2-24-e25797.pdf
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Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses.

Journal Of Virology
Chuang, Gwo-Yu GY; Lai, Yen-Ting YT; Boyington, Jeffrey C JC; Cheng, Cheng C; Geng, Hui H; Narpala, Sandeep S; Rawi, Reda R; Schmidt, Stephen D SD; Tsybovsky, Yaroslav Y; Verardi, Raffaello R; Xu, Kai K; Yang, Yongping Y; Zhang, Baoshan B; Chambers, Michael M; Changela, Anita A; Corrigan, Angela R AR; Kong, Rui R; Olia, Adam S AS; Ou, Li L; Sarfo, Edward K EK; Wang, Shuishu S; Wu, Winston W; Doria-Rose, Nicole A NA; McDermott, Adrian B AB; Mascola, John R JR; Kwong, Peter D PD
Publication Date: 2020-06-16

Variant appearance in text: CD4: T320L
PubMed Link: 32295908
Variant Present in the following documents:
  • Main text
View BVdb publication page



Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements.

Nature Communications
Henderson, Rory R; Lu, Maolin M; Zhou, Ye Y; Mu, Zekun Z; Parks, Robert R; Han, Qifeng Q; Hsu, Allen L AL; Carter, Elizabeth E; Blanchard, Scott C SC; Edwards, R J RJ; Wiehe, Kevin K; Saunders, Kevin O KO; Borgnia, Mario J MJ; Bartesaghi, Alberto A; Mothes, Walther W; Haynes, Barton F BF; Acharya, Priyamvada P; Munir Alam, S S
Publication Date: 2020-01-24

Variant appearance in text: CD4: T320L
PubMed Link: 31980614
Variant Present in the following documents:
  • 41467_2019_14196_MOESM1_ESM.pdf
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Stabilizing HIV-1 envelope glycoprotein trimers to induce neutralizing antibodies.

Retrovirology
Torrents de la Peña, Alba A; Sanders, Rogier W RW
Publication Date: 2018-09-12

Variant appearance in text: CD4: T320L
PubMed Link: 30208933
Variant Present in the following documents:
  • Main text
  • 12977_2018_Article_445.pdf
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Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity.

Journal Of Virology
Chuang, Gwo-Yu GY; Geng, Hui H; Pancera, Marie M; Xu, Kai K; Cheng, Cheng C; Acharya, Priyamvada P; Chambers, Michael M; Druz, Aliaksandr A; Tsybovsky, Yaroslav Y; Wanninger, Timothy G TG; Yang, Yongping Y; Doria-Rose, Nicole A NA; Georgiev, Ivelin S IS; Gorman, Jason J; Joyce, M Gordon MG; O'Dell, Sijy S; Zhou, Tongqing T; McDermott, Adrian B AB; Mascola, John R JR; Kwong, Peter D PD
Publication Date: 2017-05-15

Variant appearance in text: CD4: T320L
PubMed Link: 28275193
Variant Present in the following documents:
  • Main text
View BVdb publication page