Publications:

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Antiviral Activity and Crystal Structures of HIV-1 gp120 Antagonists.

International Journal Of Molecular Sciences

Curreli, Francesca F; Kwon, Young D YD; Nicolau, Isabella I; Burgos, Giancarla G; Altieri, Andrea A; Kurkin, Alexander V AV; Verardi, Raffaello R; Kwong, Peter D PD; Debnath, Asim K AK

Publication Date: 2022-12-15

Variant appearance in text: CD4: S375Y

PubMed Link: 36555641

Variant Present in the following documents:

• Main text
• ijms-23-15999.pdf

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Enhanced Ability of Plant-Derived PGT121 Glycovariants To Eliminate HIV-1-Infected Cells.

Journal Of Virology

Anand, Sai Priya SP; Ding, Shilei S; Tolbert, William D WD; Prévost, Jérémie J; Richard, Jonathan J; Gil, Hwi Min HM; Gendron-Lepage, Gabrielle G; Cheung, Wing-Fai WF; Wang, Haifeng H; Pastora, Rebecca R; Saxena, Hirak H; Wakarchuk, Warren W; Medjahed, Halima H; Wines, Bruce D BD; Hogarth, Mark M; Shaw, George M GM; Martin, Malcom A MA; Burton, Dennis R DR; Hangartner, Lars L; Evans, David T DT; Pazgier, Marzena M; Cossar, Doug D; McLean, Michael D MD; Finzi, Andrés A

Publication Date: 2021-08-25

Variant appearance in text: CD4: S375Y

PubMed Link: 34232070

Variant Present in the following documents:

• Main text

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T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers.

Nature Medicine

Arunachalam, Prabhu S PS; Charles, Tysheena P TP; Joag, Vineet V; Bollimpelli, Venkata S VS; Scott, Madeleine K D MKD; Wimmers, Florian F; Burton, Samantha L SL; Labranche, Celia C CC; Petitdemange, Caroline C; Gangadhara, Sailaja S; Styles, Tiffany M TM; Quarnstrom, Clare F CF; Walter, Korey A KA; Ketas, Thomas J TJ; Legere, Traci T; Jagadeesh Reddy, Pradeep Babu PB; Kasturi, Sudhir Pai SP; Tsai, Anthony A; Yeung, Bertrand Z BZ; Gupta, Shakti S; Tomai, Mark M; Vasilakos, John J; Shaw, George M GM; Kang, Chil-Yong CY; Moore, John P JP; Subramaniam, Shankar S; Khatri, Purvesh P; Montefiori, David D; Kozlowski, Pamela A PA; Derdeyn, Cynthia A CA; Hunter, Eric E; Masopust, David D; Amara, Rama R RR; Pulendran, Bali B

Publication Date: 2020-06

Variant appearance in text: CD4: S375Y

PubMed Link: 32393800

Variant Present in the following documents:

• 41591_2020_Article_858.pdf

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Selective use of primate CD4 receptors by HIV-1.

Plos Biology

Warren, Cody J CJ; Meyerson, Nicholas R NR; Dirasantha, Obaiah O; Feldman, Emily R ER; Wilkerson, Gregory K GK; Sawyer, Sara L SL

Publication Date: 2019-06

Variant appearance in text: CD4: S375Y

PubMed Link: 31181085

Variant Present in the following documents:

• Main text

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Synthesis, Antiviral Activity, and Structure-Activity Relationship of 1,3-Benzodioxolyl Pyrrole-Based Entry Inhibitors Targeting the Phe43 Cavity in HIV-1 gp120.

Chemmedchem

Curreli, Francesca F; Belov, Dmitry S DS; Ahmed, Shahad S; Ramesh, Ranjith R RR; Kurkin, Alexander V AV; Altieri, Andrea A; Debnath, Asim K AK

Publication Date: 2018-11-06

Variant appearance in text: CD4: S375Y

PubMed Link: 30257071

Variant Present in the following documents:

• Main text

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Structure-based lead optimization to improve antiviral potency and ADMET properties of phenyl-1H-pyrrole-carboxamide entry inhibitors targeted to HIV-1 gp120.

European Journal Of Medicinal Chemistry

Curreli, Francesca F; Belov, Dmitry S DS; Kwon, Young Do YD; Ramesh, Ranjith R; Furimsky, Anna M AM; O'Loughlin, Kathleen K; Byrge, Patricia C PC; Iyer, Lalitha V LV; Mirsalis, Jon C JC; Kurkin, Alexander V AV; Altieri, Andrea A; Debnath, Asim K AK

Publication Date: 2018-06-25

Variant appearance in text: CD4: S375Y

PubMed Link: 29860061

Variant Present in the following documents:

• Main text

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Saturation Mutagenesis of the HIV-1 Envelope CD4 Binding Loop Reveals Residues Controlling Distinct Trimer Conformations.

Plos Pathogens

Duenas-Decamp, Maria M; Jiang, Li L; Bolon, Daniel D; Clapham, Paul R PR

Publication Date: 2016-11

Variant appearance in text: CD4: S375Y

PubMed Link: 27820858

Variant Present in the following documents:

• Main text
• ppat.1005988.pdf

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Synthesis, antiviral activity and resistance of a novel small molecule HIV-1 entry inhibitor.

Bioorganic & Medicinal Chemistry

Curreli, Francesca F; Haque, Kashfia K; Xie, Lihua L; Qiu, Qian Q; Xu, Jinfeng J; Yong, Weizhong W; Tong, Xiaohe X; Debnath, Asim K AK

Publication Date: 2015-12-15

Variant appearance in text: CD4: S375Y

PubMed Link: 26602829

Variant Present in the following documents:

• Main text

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