Sequences in glycoprotein gp41, the CD4 binding site, and the V2 domain regulate sensitivity and resistance of HIV-1 to broadly neutralizing antibodies.
Journal Of Virology
O'Rourke, Sara M SM; Schweighardt, Becky B; Phung, Pham P; Mesa, Kathryn A KA; Vollrath, Aaron L AL; Tatsuno, Gwen P GP; To, Briana B; Sinangil, Faruk F; Limoli, Kay K; Wrin, Terri T; Berman, Phillip W PW
In vivo patterns of resistance to the HIV attachment inhibitor BMS-488043.
Antimicrobial Agents And Chemotherapy
Zhou, Nannan N; Nowicka-Sans, Beata B; Zhang, Sharon S; Fan, Li L; Fang, Jie J; Fang, Hua H; Gong, Yi-Fei YF; Eggers, Betsy B; Langley, David R DR; Wang, Tao T; Kadow, John J; Grasela, Dennis D; Hanna, George J GJ; Alexander, Louis L; Colonno, Richard R; Krystal, Mark M; Lin, Pin-Fang PF
Human immunodeficiency virus type 1 escape from cyclotriazadisulfonamide-induced CD4-targeted entry inhibition is associated with increased neutralizing antibody susceptibility.
Journal Of Virology
Vermeire, Kurt K; Van Laethem, Kristel K; Janssens, Wouter W; Bell, Thomas W TW; Schols, Dominique D
Biochemical and genetic characterizations of a novel human immunodeficiency virus type 1 inhibitor that blocks gp120-CD4 interactions.
Journal Of Virology
Guo, Qi Q; Ho, Hsu-Tso HT; Dicker, Ira I; Fan, Li L; Zhou, Nannan N; Friborg, Jacques J; Wang, Tao T; McAuliffe, Brian V BV; Wang, Hwei-Gene Heidi HG; Rose, Ronald E RE; Fang, Hua H; Scarnati, Helen T HT; Langley, David R DR; Meanwell, Nicholas A NA; Abraham, Ralph R; Colonno, Richard J RJ; Lin, Pin-Fang PF