CD4 c.1333_1334delinsGC ;(p.C445A)

Variant ID: 12-6928067-TG-GC

NM_000616.4(CD4):c.1333_1334delinsGC;(p.C445A)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


Only five of 10 strictly conserved disulfide bonds are essential for folding and eight for function of the HIV-1 envelope glycoprotein.

Molecular Biology Of The Cell
van Anken, Eelco E; Sanders, Rogier W RW; Liscaljet, I Marije IM; Land, Aafke A; Bontjer, Ilja I; Tillemans, Sonja S; Nabatov, Alexey A AA; Paxton, William A WA; Berkhout, Ben B; Braakman, Ineke I
Publication Date: 2008-10

Variant appearance in text: CD4: C445A
PubMed Link: 18653472
Variant Present in the following documents:
  • Main text
View BVdb publication page



The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

Journal Of Virology
Scanlan, Christopher N CN; Pantophlet, Ralph R; Wormald, Mark R MR; Ollmann Saphire, Erica E; Stanfield, Robyn R; Wilson, Ian A IA; Katinger, Hermann H; Dwek, Raymond A RA; Rudd, Pauline M PM; Burton, Dennis R DR
Publication Date: 2002-07

Variant appearance in text: CD4: C445A
PubMed Link: 12072529
Variant Present in the following documents:
  • Main text
View BVdb publication page