TPH2 c.608+5263G>T

Variant ID: 12-72348698-G-T

NM_173353.3(TPH2):c.608+5263G>T

This variant was identified in 31 publications

View GRCh38 version.




Publications:


Serotonin-Related Functional Genetic Variants Affect the Occurrence of Psychiatric and Motor Adverse Events of Dopaminergic Treatment in Parkinson's Disease: A Retrospective Cohort Study.

Journal Of Personalized Medicine
Redenšek, Sara S; Blagus, Tanja T; Trošt, Maja M; Dolžan, Vita V
Publication Date: 2022-02-11

Variant appearance in text: TPH2: 608+5263G>T; rs1843809
PubMed Link: 35207756
Variant Present in the following documents:
  • Main text
  • jpm-12-00266.pdf
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The 5-HTTLPR-rs25531 S-A-S-A Haplotype and Chronic Stress Moderate the Association Between Acute Stress and Internalizing Mental Disorders Among HIV+ Children and Adolescents in Uganda.

Frontiers In Genetics
Kalungi, Allan A; Womersley, Jacqueline S JS; Kinyanda, Eugene E; Joloba, Moses L ML; Ssembajjwe, Wilber W; Nsubuga, Rebecca N RN; Seedat, Soraya S; Hemmings, Sian M J SMJ
Publication Date: 2021

Variant appearance in text: rs1843809
PubMed Link: 33968131
Variant Present in the following documents:
  • Main text
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Brazilian Psychiatric Association guidelines for the management of suicidal behavior. Part 1. Risk factors, protective factors, and assessment.

Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999)
Baldaçara, Leonardo L; Rocha, Gislene A GA; Leite, Verônica da S VDS; Porto, Deisy M DM; Grudtner, Roberta R RR; Diaz, Alexandre P AP; Meleiro, Alexandrina A; Correa, Humberto H; Tung, Teng C TC; Quevedo, João J; da Silva, Antônio G AG
Publication Date: 2021

Variant appearance in text: rs1843809
PubMed Link: 33111773
Variant Present in the following documents:
  • bjp-43-05-525-s001.pdf
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Machine learning classification of ADHD and HC by multimodal serotonergic data.

Translational Psychiatry
Kautzky, A A; Vanicek, T T; Philippe, C C; Kranz, G S GS; Wadsak, W W; Mitterhauser, M M; Hartmann, A A; Hahn, A A; Hacker, M M; Rujescu, D D; Kasper, S S; Lanzenberger, R R
Publication Date: 2020-04-07

Variant appearance in text: rs1843809
PubMed Link: 32265436
Variant Present in the following documents:
  • Main text
  • 41398_2020_Article_781.pdf
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Association Analysis of 14 Candidate Gene Polymorphism with Depression and Stress among Gestational Diabetes Mellitus.

Genes
Lee, Kai Wei KW; Ching, Siew Mooi SM; Ramachandran, Vasudevan V; Tusimin, Maiza M; Mohd Nordin, Noraihan N; Chong, Seng Choi SC; Hoo, Fan Kee FK
Publication Date: 2019-11-30

Variant appearance in text: rs1843809
PubMed Link: 31801286
Variant Present in the following documents:
  • Main text
  • genes-10-00988.pdf
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Association between single nucleotide polymorphisms of TPH1 and TPH2 genes, and depressive disorders.

Journal Of Cellular And Molecular Medicine
Wigner, Paulina P; Czarny, Piotr P; Synowiec, Ewelina E; Bijak, Michał M; Białek, Katarzyna K; Talarowska, Monika M; Galecki, Piotr P; Szemraj, Janusz J; Sliwinski, Tomasz T
Publication Date: 2018-03

Variant appearance in text: TPH2: 608+5263G>T; rs1843809
PubMed Link: 29314569
Variant Present in the following documents:
  • Main text
  • JCMM-22-1778.pdf
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No genetic association between attention-deficit/hyperactivity disorder (ADHD) and Parkinson's disease in nine ADHD candidate SNPs.

Attention Deficit And Hyperactivity Disorders
Geissler, Julia M JM; , ; Romanos, Marcel M; Gerlach, Manfred M; Berg, Daniela D; Schulte, Claudia C
Publication Date: 2017-06

Variant appearance in text: rs1843809
PubMed Link: 28176268
Variant Present in the following documents:
  • Main text
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Common and specific genes and peripheral biomarkers in children and adults with attention-deficit/hyperactivity disorder.

The World Journal Of Biological Psychiatry : The Official Journal Of The World Federation Of Societies Of Biological Psychiatry
Bonvicini, Cristian C; Faraone, Stephen V SV; Scassellati, Catia C
Publication Date: 2018-03

Variant appearance in text: rs1843809
PubMed Link: 28097908
Variant Present in the following documents:
  • Main text
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Neuroimmune Interface in the Comorbidity between Alcohol Use Disorder and Major Depression.

Frontiers In Immunology
Neupane, Sudan Prasad SP
Publication Date: 2016

Variant appearance in text: rs1843809
PubMed Link: 28082989
Variant Present in the following documents:
  • Main text
  • fimmu-07-00655.pdf
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Association of tryptophan hydroxylase-2 polymorphisms with oppositional defiant disorder in a Chinese Han population.

Behavioral And Brain Functions : Bbf
Wang, Chang-Hong CH; Liu, Cong C; Cong, En-Zhao EZ; Xu, Gai-Ling GL; Lv, Ting-Ting TT; Zhang, Ying-Li YL; Ning, Qiu-Fen QF; Wang, Ji-Kang JK; Nie, Hui-Yao HY; Li, Yan Y
Publication Date: 2016-11-21

Variant appearance in text: rs1843809
PubMed Link: 27871272
Variant Present in the following documents:
  • Main text
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Preliminary evidence for association of genetic variants in pri-miR-34b/c and abnormal miR-34c expression with attention deficit and hyperactivity disorder.

Translational Psychiatry
Garcia-Martínez, I I; Sánchez-Mora, C C; Pagerols, M M; Richarte, V V; Corrales, M M; Fadeuilhe, C C; Cormand, B B; Casas, M M; Ramos-Quiroga, J A JA; Ribasés, M M
Publication Date: 2016-08-30

Variant appearance in text: rs1843809
PubMed Link: 27576168
Variant Present in the following documents:
View BVdb publication page



Testing for the mediating role of endophenotypes using molecular genetic data in a twin study of ADHD traits.

American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Pinto, Rebecca R; Asherson, Philip P; Ilott, Nicholas N; Cheung, Celeste H M CH; Kuntsi, Jonna J
Publication Date: 2016-10

Variant appearance in text: rs1843809
PubMed Link: 27230021
Variant Present in the following documents:
  • Main text
  • AJMG-171-982.pdf
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Multiple SNP Set Analysis for Genome-Wide Association Studies Through Bayesian Latent Variable Selection.

Genetic Epidemiology
Lu, Zhao-Hua ZH; Zhu, Hongtu H; Knickmeyer, Rebecca C RC; Sullivan, Patrick F PF; Williams, Stephanie N SN; Zou, Fei F; ,
Publication Date: 2015-12

Variant appearance in text: rs1843809
PubMed Link: 26515609
Variant Present in the following documents:
  • Main text
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Dopamine and serotonin genetic risk scores predicting substance and nicotine use in attention deficit/hyperactivity disorder.

Addiction Biology
Groenman, Annabeth P AP; Greven, Corina U CU; van Donkelaar, Marjolein M J MM; Schellekens, Arnt A; van Hulzen, Kimm J E KJ; Rommelse, Nanda N; Hartman, Catharina A CA; Hoekstra, Pieter J PJ; Luman, Marjolein M; Franke, Barbara B; Faraone, Stephen V SV; Oosterlaan, Jaap J; Buitelaar, Jan K JK
Publication Date: 2016-07

Variant appearance in text: rs1843809
PubMed Link: 25752199
Variant Present in the following documents:
  • Main text
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Genetic prediction of antidepressant drug response and nonresponse in Korean patients.

Plos One
Lim, Shinn-Won SW; Won, Hong-Hee HH; Kim, Hyeran H; Myung, Woojae W; Kim, Seonwoo S; Kim, Ka-Kyung KK; Carroll, Bernard J BJ; Kim, Jong-Won JW; Kim, Doh Kwan DK
Publication Date: 2014

Variant appearance in text: rs1843809
PubMed Link: 25226239
Variant Present in the following documents:
  • Main text
  • pone.0107098.pdf
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Candidate gene associations with withdrawn behavior.

Journal Of Child Psychology And Psychiatry, And Allied Disciplines
Rubin, David H DH; Althoff, Robert R RR; Ehli, Erik A EA; Davies, Gareth E GE; Rettew, David C DC; Crehan, Eileen T ET; Walkup, John T JT; Hudziak, James J JJ
Publication Date: 2013-12

Variant appearance in text: rs1843809
PubMed Link: 23808549
Variant Present in the following documents:
  • Main text
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Personalized medicine in psychiatry: problems and promises.

Bmc Medicine
Ozomaro, Uzoezi U; Wahlestedt, Claes C; Nemeroff, Charles B CB
Publication Date: 2013-05-16

Variant appearance in text: rs1843809
PubMed Link: 23680237
Variant Present in the following documents:
  • Main text
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Associations between prefrontal γ-aminobutyric acid concentration and the tryptophan hydroxylase isoform 2 gene, a panic disorder risk allele in women.

The International Journal Of Neuropsychopharmacology
Preuss, Nora N; Salehi, Basira B; van der Veen, Jan Willem JW; Shen, Jun J; Drevets, Wayne C WC; Hodgkinson, Colin C; Goldman, David D; Hasler, Gregor G
Publication Date: 2013-09

Variant appearance in text: rs1843809
PubMed Link: 23552096
Variant Present in the following documents:
  • Main text
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Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis.

Plos Medicine
Tansey, Katherine E KE; Guipponi, Michel M; Perroud, Nader N; Bondolfi, Guido G; Domenici, Enrico E; Evans, David D; Hall, Stephanie K SK; Hauser, Joanna J; Henigsberg, Neven N; Hu, Xiaolan X; Jerman, Borut B; Maier, Wolfgang W; Mors, Ole O; O'Donovan, Michael M; Peters, Tim J TJ; Placentino, Anna A; Rietschel, Marcella M; Souery, Daniel D; Aitchison, Katherine J KJ; Craig, Ian I; Farmer, Anne A; Wendland, Jens R JR; Malafosse, Alain A; Holmans, Peter P; Lewis, Glyn G; Lewis, Cathryn M CM; Stensbøl, Tine Bryan TB; Kapur, Shitij S; McGuffin, Peter P; Uher, Rudolf R
Publication Date: 2012

Variant appearance in text: rs1843809
PubMed Link: 23091423
Variant Present in the following documents:
  • pmed.1001326.s001.pdf
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TPH2 gene polymorphisms and major depression--a meta-analysis.

Plos One
Gao, Jin J; Pan, Zhenglun Z; Jiao, Zhian Z; Li, Feng F; Zhao, Guoqing G; Wei, Qianqian Q; Pan, Fang F; Evangelou, Evangelos E
Publication Date: 2012

Variant appearance in text: rs1843809
PubMed Link: 22693556
Variant Present in the following documents:
  • Main text
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The genetics of attention deficit/hyperactivity disorder in adults, a review.

Molecular Psychiatry
Franke, B B; Faraone, S V SV; Asherson, P P; Buitelaar, J J; Bau, C H D CH; Ramos-Quiroga, J A JA; Mick, E E; Grevet, E H EH; Johansson, S S; Haavik, J J; Lesch, K-P KP; Cormand, B B; Reif, A A; ,
Publication Date: 2012-10

Variant appearance in text: rs1843809
PubMed Link: 22105624
Variant Present in the following documents:
  • Main text
  • mp2011138a.pdf
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Toward a better understanding of ADHD: LPHN3 gene variants and the susceptibility to develop ADHD.

Attention Deficit And Hyperactivity Disorders
Arcos-Burgos, Mauricio M; Muenke, Maximilian M
Publication Date: 2010-11

Variant appearance in text: rs1843809
PubMed Link: 21432600
Variant Present in the following documents:
  • Main text
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Pharmacogenetics of antidepressant response.

Journal Of Psychiatry & Neuroscience : Jpn
Porcelli, Stefano S; Drago, Antonio A; Fabbri, Chiara C; Gibiino, Sara S; Calati, Raffaella R; Serretti, Alessandro A
Publication Date: 2011-03

Variant appearance in text: rs1843809
PubMed Link: 21172166
Variant Present in the following documents:
  • Main text
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A candidate gene association study of alcohol consumption in young women.

Alcoholism, Clinical And Experimental Research
Agrawal, Arpana A; Lynskey, Michael T MT; Todorov, Alexandre A AA; Schrage, Andrew J AJ; Littlefield, Andrew K AK; Grant, Julia D JD; Zhu, Qin Q; Nelson, Elliot C EC; Madden, Pamela A F PA; Bucholz, Kathleen K KK; Sher, Kenneth J KJ; Heath, Andrew C AC
Publication Date: 2011-03

Variant appearance in text: rs1843809
PubMed Link: 21143251
Variant Present in the following documents:
  • Main text
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Genetic influences on attention deficit hyperactivity disorder symptoms from age 2 to 3: a quantitative and molecular genetic investigation.

Bmc Psychiatry
Ilott, Nicholas E NE; Saudino, Kimberly J KJ; Asherson, Philip P
Publication Date: 2010-12-01

Variant appearance in text: rs1843809
PubMed Link: 21122117
Variant Present in the following documents:
  • Main text
  • 1471-244X-10-102.pdf
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Measured gene-by-environment interaction in relation to attention-deficit/hyperactivity disorder.

Journal Of The American Academy Of Child And Adolescent Psychiatry
Nigg, Joel J; Nikolas, Molly M; Burt, S Alexandra SA
Publication Date: 2010-09

Variant appearance in text: rs1843809
PubMed Link: 20732623
Variant Present in the following documents:
  • Main text
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Molecular genetics of attention deficit hyperactivity disorder.

The Psychiatric Clinics Of North America
Faraone, Stephen V SV; Mick, Eric E
Publication Date: 2010-03

Variant appearance in text: rs1843809
PubMed Link: 20159345
Variant Present in the following documents:
  • Main text
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Risk-taking behavior in a gambling task associated with variations in the tryptophan hydroxylase 2 gene: relevance to psychiatric disorders.

Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
Juhasz, Gabriella G; Downey, Darragh D; Hinvest, Neal N; Thomas, Emma E; Chase, Diana D; Toth, Zoltan G ZG; Lloyd-Williams, Kathryn K; Mekli, Krisztina K; Platt, Hazel H; Payton, Antony A; Bagdy, Gyorgy G; Elliott, Rebecca R; Deakin, J F William JF; Anderson, Ian M IM
Publication Date: 2010-04

Variant appearance in text: rs1843809
PubMed Link: 20043001
Variant Present in the following documents:
  • Main text
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Epistasis between IL1A, IL1B, TNF, HTR2A, 5-HTTLPR and TPH2 variations does not impact alcohol dependence disorder features.

International Journal Of Environmental Research And Public Health
Drago, Antonio A; Liappas, Ioannis I; Petio, Carmine C; Albani, Diego D; Forloni, Gianluigi G; Malitas, Petros P; Piperi, Christina C; Politis, Antonis A; Tzavellas, Elias O EO; Zisaki, Katerina K KK; Prato, Francesca F; Batelli, Sara S; Polito, Letizia L; De Ronchi, Diana D; Paparrigopoulos, Thomas T; Kalofoutis, Anastasios A; Serretti, Alessandro A
Publication Date: 2009-07

Variant appearance in text: rs1843809
PubMed Link: 19742166
Variant Present in the following documents:
  • Main text
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Preferential transmission of paternal alleles at risk genes in attention-deficit/hyperactivity disorder.

American Journal Of Human Genetics
Hawi, Ziarih Z; Segurado, Ricardo R; Conroy, Judith J; Sheehan, Karen K; Lowe, Naomi N; Kirley, Aiveen A; Shields, Denis D; Fitzgerald, Michael M; Gallagher, Louise L; Gill, Michael M
Publication Date: 2005-12

Variant appearance in text: rs1843809
PubMed Link: 16380908
Variant Present in the following documents:
  • Main text
View BVdb publication page