Fragmentation patterns and personalized sequencing of cell-free DNA in urine and plasma of glioma patients.
Embo Molecular Medicine
Mouliere, Florent F; Smith, Christopher G CG; Heider, Katrin K; Su, Jing J; van der Pol, Ymke Y; Thompson, Mareike M; Morris, James J; Wan, Jonathan C M JCM; Chandrananda, Dineika D; Hadfield, James J; Grzelak, Marta M; Hudecova, Irena I; Couturier, Dominique-Laurent DL; Cooper, Wendy W; Zhao, Hui H; Gale, Davina D; Eldridge, Matthew M; Watts, Colin C; Brindle, Kevin K; Rosenfeld, Nitzan N; Mair, Richard R
Publication Date: 2021-08-09
Variant appearance in text: LIG4: 1704T>C; Asp568=; rs1805386
Influence of single nucleotide polymorphisms among cigarette smoking and non-smoking patients with coronary artery disease, urinary bladder cancer and lung cancer.
Plos One
Laytragoon Lewin, Nongnit N; Karlsson, Jan-Erik JE; Robinsson, David D; Fagerberg, Matida M; Kentsson, Magnus M; Sayardoust, Shariel S; Nilsson, Mats M; Shamoun, Levar L; Andersson, Bengt-Åke BÅ; Löfgren, Sture S; Rutqvist, Lars Erik LE; Lewin, Freddi F
Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells.
Npj Systems Biology And Applications
Immanuel, Selva Rupa Christinal SRC; Ghanate, Avinash D AD; Parmar, Dharmeshkumar S DS; Yadav, Ritu R; Uthup, Riya R; Panchagnula, Venkateswarlu V; Raghunathan, Anu A
Publication Date: 2021-01-08
Variant appearance in text: LIG4: 1704T>C; rs1805386
Somatic mutations in the DNA repairome in prostate cancers in African Americans and Caucasians.
Oncogene
Yadav, Santosh S; Anbalagan, Muralidharan M; Baddoo, Melody M; Chellamuthu, Vinodh K VK; Mukhopadhyay, Sudurika S; Woods, Carol C; Jiang, Wei W; Moroz, Krzysztof K; Flemington, Erik K EK; Makridakis, Nick N
Publication Date: 2020-05
Variant appearance in text: LIG4: D568D; rs1805386
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines.
Scientific Reports
Skowron, Margaretha A MA; Petzsch, Patrick P; Hardt, Karin K; Wagner, Nicholas N; Beier, Manfred M; Stepanow, Stefanie S; Drechsler, Matthias M; Rieder, Harald H; Köhrer, Karl K; Niegisch, Günter G; Hoffmann, Michèle J MJ; Schulz, Wolfgang A WA
Publication Date: 2019-10-09
Variant appearance in text: LIG4: D568D; rs1805386
Investigation of DNA repair-related SNPs underlying susceptibility to papillary thyroid carcinoma reveals MGMT as a novel candidate gene in Belarusian children exposed to radiation.
Bmc Cancer
Lonjou, Christine C; Damiola, Francesca F; Moissonnier, Monika M; Durand, Geoffroy G; Malakhova, Irina I; Masyakin, Vladimir V; Le Calvez-Kelm, Florence F; Cardis, Elisabeth E; Byrnes, Graham G; Kesminiene, Ausrele A; Lesueur, Fabienne F
Publication Date: 2017-05-12
Variant appearance in text: LIG4: D568D; rs1805386
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Publication Date: 2015-12-08
Variant appearance in text: LIG4: D568D; rs1805386
What's your poison? Impact of individual repair capacity on the outcomes of genotoxic therapies in cancer. Part II - information content and validity of biomarkers for individual repair capacity in the assessment of outcomes of anticancer therapy.
Biotechnology, Biotechnological Equipment
Petkova, Rumena R; Chelenkova, Pavlina P; Georgieva, Elena E; Chakarov, Stoian S
Single nucleotide polymorphisms in DNA repair genes as risk factors associated to prostate cancer progression.
Bmc Medical Genetics
Henríquez-Hernández, Luis Alberto LA; Valenciano, Almudena A; Foro-Arnalot, Palmira P; Álvarez-Cubero, María Jesús MJ; Cozar, José Manuel JM; Suárez-Novo, José Francisco JF; Castells-Esteve, Manel M; Fernández-Gonzalo, Pablo P; De-Paula-Carranza, Belén B; Ferrer, Montse M; Guedea, Ferrán F; Sancho-Pardo, Gemma G; Craven-Bartle, Jordi J; Ortiz-Gordillo, María José MJ; Cabrera-Roldán, Patricia P; Herrera-Ramos, Estefanía E; Rodríguez-Gallego, Carlos C; Rodríguez-Melcón, Juan Ignacio JI; Lara, Pedro C PC
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Publication Date: 2014
Variant appearance in text: LIG4: D568D; rs1805386
The role of single nucleotide polymorphisms in predicting prostate cancer risk and therapeutic decision making.
Biomed Research International
Van den Broeck, Thomas T; Joniau, Steven S; Clinckemalie, Liesbeth L; Helsen, Christine C; Prekovic, Stefan S; Spans, Lien L; Tosco, Lorenzo L; Van Poppel, Hendrik H; Claessens, Frank F
Non-Hodgkin lymphoma risk and variants in genes controlling lymphocyte development.
Plos One
Schuetz, Johanna M JM; Daley, Denise D; Leach, Stephen S; Conde, Lucia L; Berry, Brian R BR; Gallagher, Richard P RP; Connors, Joseph M JM; Gascoyne, Randy D RD; Bracci, Paige M PM; Skibola, Christine F CF; Spinelli, John J JJ; Brooks-Wilson, Angela R AR
Polymorphisms in DNA-repair genes in a cohort of prostate cancer patients from different areas in Spain: heterogeneity between populations as a confounding factor in association studies.
Plos One
Henríquez-Hernández, Luis Alberto LA; Valenciano, Almudena A; Foro-Arnalot, Palmira P; Alvarez-Cubero, María Jesús MJ; Cozar, José Manuel JM; Suárez-Novo, José Francisco JF; Castells-Esteve, Manel M; Ayala-Gil, Adriana A; Fernández-Gonzalo, Pablo P; Ferrer, Montse M; Guedea, Ferrán F; Sancho-Pardo, Gemma G; Craven-Bartle, Jordi J; Ortiz-Gordillo, María José MJ; Cabrera-Roldán, Patricia P; Herrera-Ramos, Estefanía E; Lara, Pedro C PC
Genome-wide association study identifies a region on chromosome 11q14.3 associated with late rectal bleeding following radiation therapy for prostate cancer.
Radiotherapy And Oncology : Journal Of The European Society For Therapeutic Radiology And Oncology
Kerns, Sarah L SL; Stock, Richard G RG; Stone, Nelson N NN; Blacksburg, Seth R SR; Rath, Lynda L; Vega, Ana A; Fachal, Laura L; Gómez-Caamaño, Antonio A; De Ruysscher, Dirk D; Lammering, Guido G; Parliament, Matthew M; Blackshaw, Michael M; Sia, Michael M; Cesaretti, Jamie J; Terk, Mitchell M; Hixson, Rosetta R; Rosenstein, Barry S BS; Ostrer, Harry H
Genetic variation in radiation and platinum pathways predicts severe acute radiation toxicity in patients with esophageal adenocarcinoma treated with cisplatin-based preoperative radiochemotherapy: results from the Eastern Cooperative Oncology Group.
Cancer Chemotherapy And Pharmacology
Yoon, H H HH; Catalano, P P; Gibson, M K MK; Skaar, T C TC; Philips, S S; Montgomery, E A EA; Hafez, M J MJ; Powell, M M; Liu, G G; Forastiere, A A AA; Benson, A B AB; Kleinberg, L R LR; Murphy, K M KM
Publication Date: 2011-10
Variant appearance in text: LIG4: D568D; rs1805386
Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer.
Plos One
Schildkraut, Joellen M JM; Iversen, Edwin S ES; Wilson, Melanie A MA; Clyde, Merlise A MA; Moorman, Patricia G PG; Palmieri, Rachel T RT; Whitaker, Regina R; Bentley, Rex C RC; Marks, Jeffrey R JR; Berchuck, Andrew A
DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma.
Neuro-Oncology
Rajaraman, Preetha P; Hutchinson, Amy A; Wichner, Sara S; Black, Peter M PM; Fine, Howard A HA; Loeffler, Jay S JS; Selker, Robert G RG; Shapiro, William R WR; Rothman, Nathaniel N; Linet, Martha S MS; Inskip, Peter D PD
Publication Date: 2010-01
Variant appearance in text: LIG4: D568D; rs1805386
Role of genetic polymorphisms and ovarian cancer susceptibility.
Molecular Oncology
Fasching, Peter A PA; Gayther, Simon S; Pearce, Leigh L; Schildkraut, Joellen M JM; Goode, Ellen E; Thiel, Falk F; Chenevix-Trench, Georgia G; Chang-Claude, Jenny J; Wang-Gohrke, Shan S; Ramus, Susan S; Pharoah, Paul P; Berchuck, Andrew A; ,
Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium.
British Journal Of Cancer
Pearce, C L CL; Near, A M AM; Van Den Berg, D J DJ; Ramus, S J SJ; Gentry-Maharaj, A A; Menon, U U; Gayther, S A SA; Anderson, A R AR; Edlund, C K CK; Wu, A H AH; Chen, X X; Beesley, J J; Webb, P M PM; Holt, S K SK; Chen, C C; Doherty, J A JA; Rossing, M A MA; Whittemore, A S AS; McGuire, V V; DiCioccio, R A RA; Goodman, M T MT; Lurie, G G; Carney, M E ME; Wilkens, L R LR; Ness, R B RB; Moysich, K B KB; Edwards, R R; Jennison, E E; Kjaer, S K SK; Hogdall, E E; Hogdall, C K CK; Goode, E L EL; Sellers, T A TA; Vierkant, R A RA; Cunningham, J M JM; Cunningham, J C JC; Schildkraut, J M JM; Berchuck, A A; Moorman, P G PG; Iversen, E S ES; Cramer, D W DW; Terry, K L KL; Vitonis, A F AF; Titus-Ernstoff, L L; Song, H H; Pharoah, P D P PD; Spurdle, A B AB; Anton-Culver, H H; Ziogas, A A; Brewster, W W; Galitovskiy, V V; Chenevix-Trench, G G; , ; ,