Publications:

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Implementation of a Renal Precision Medicine Program: Clinician Attitudes and Acceptance.

Life (Basel, Switzerland)

KM Spiech, PR Tripathy, AM Woodcock, NA Sheth, KS Collins, K Kannegolla, AD Sinha, AA Sharfuddin, VM Pratt, M Khalid, DS Hains, SM Moe, TC Skaar, RN Moorthi, MT Eadon

Publication Date: 2020-03-26

Variant appearance in text: rs6046

PubMed Link: 32224869

Variant Present in the following documents:

• Main text

View BVdb publication page

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Introducing the first whole genomes of nationals from the United Arab Emirates.

Scientific Reports

HS AlSafar, M Al-Ali, GD Elbait, MH Al-Maini, D Ruta, B Peramo, A Henschel, GK Tay

Publication Date: 2019-10-11

Variant appearance in text: rs6046

PubMed Link: 31604968

Variant Present in the following documents:

• 41598_2019_50876_MOESM1_ESM.xlsx

View BVdb publication page

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Sex-Specific Genetic Susceptibility to Adverse Neurodevelopmental Outcome in Offspring of Pregnancies at Risk of Early Preterm Delivery.

American Journal Of Perinatology

MW Varner, MM Costantine, KA Jablonski, DJ Rouse, BM Mercer, KJ Leveno, UM Reddy, C Buhimschi, RJ Wapner, Y Sorokin, JM Thorp, SM Ramin, FD Malone, M Carpenter, MJ O'sullivan, AM Peaceman, DJ Dudley, SN Caritis,

Publication Date: 2020-02

Variant appearance in text: rs6046

PubMed Link: 30731481

Variant Present in the following documents:

• Main text

View BVdb publication page

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Analytical validity of a genotyping assay for use with personalized antihypertensive and chronic kidney disease therapy.

Pharmacogenetics And Genomics

KS Collins, VM Pratt, WM Stansberry, EB Medeiros, K Kannegolla, M Swart, TC Skaar, AB Chapman, BS Decker, RN Moorthi, MT Eadon

Publication Date: 2019-01

Variant appearance in text: rs6046

PubMed Link: 30489456

Variant Present in the following documents:

• Main text
• nihms-1512061.pdf
• NIHMS1512061-supplement-Supplemental_Table_1.docx

View BVdb publication page

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Polymorphism of R353Q (rs6046) in factor VII and the risk of myocardial infarction: A systematic review and meta-analysis.

Medicine

H Huang, W Long, W Zhao, L Zou, Y Song, J Zuo, Z Yang

Publication Date: 2018-09

Variant appearance in text: rs6046

PubMed Link: 30278561

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pharmacogenomic studies of hypertension: paving the way for personalized antihypertensive treatment.

Expert Review Of Precision Medicine And Drug Development

MT Eadon, SH Kanuri, AB Chapman

Publication Date: 2018

Variant appearance in text: rs6046

PubMed Link: 29888336

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic Variation, Magnesium Sulfate Exposure, and Adverse Neurodevelopmental Outcomes Following Preterm Birth.

American Journal Of Perinatology

EAS Clark, SJ Weiner, DJ Rouse, BM Mercer, UM Reddy, JD Iams, RJ Wapner, Y Sorokin, FD Malone, MJ O'Sullivan, AM Peaceman, GDV Hankins, DJ Dudley, SN Caritis,

Publication Date: 2018-08

Variant appearance in text: rs6046

PubMed Link: 29510423

Variant Present in the following documents:

• Main text

View BVdb publication page

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Expanded carrier screening and preimplantation genetic diagnosis in a couple who delivered a baby affected with congenital factor VII deficiency.

Bmc Medical Genetics

WB He, YQ Tan, X Hu, W Li, B Xiong, KL Luo, F Gong, GX Lu, G Lin, J Du

Publication Date: 2018-01-24

Variant appearance in text: F7: 1238G>C

PubMed Link: 29368589

Variant Present in the following documents:

• Main text

View BVdb publication page

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Associations of activated coagulation factor VII and factor VIIa-antithrombin levels with genome-wide polymorphisms and cardiovascular disease risk.

Journal Of Thrombosis And Haemostasis : Jth

NC Olson, LM Raffield, LA Lange, EM Lange, WT Longstreth, G Chauhan, S Debette, S Seshadri, AP Reiner, RP Tracy

Publication Date: 2018-01

Variant appearance in text: rs6046

PubMed Link: 29112333

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association between kidney function and genetic polymorphisms in atherosclerotic and chronic kidney diseases: A cross-sectional study in Japanese male workers.

Plos One

Y Kubo, T Imaizumi, M Ando, M Nakatochi, Y Yasuda, H Honda, Y Kuwatsuka, S Kato, K Kikuchi, T Kondo, M Iwata, T Nakashima, H Yasui, H Takamatsu, H Okajima, Y Yoshida, S Maruyama

Publication Date: 2017

Variant appearance in text: rs6046

PubMed Link: 29016630

Variant Present in the following documents:

• pone.0185476.s001.docx
• pone.0185476.s002.docx

View BVdb publication page

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Candidate SNP Markers of Familial and Sporadic Alzheimer's Diseases Are Predicted by a Significant Change in the Affinity of TATA-Binding Protein for Human Gene Promoters.

Frontiers In Aging Neuroscience

P Ponomarenko, I Chadaeva, DA Rasskazov, E Sharypova, EV Kashina, I Drachkova, D Zhechev, MP Ponomarenko, LK Savinkova, N Kolchanov

Publication Date: 2017

Variant appearance in text: rs6046

PubMed Link: 28775688

Variant Present in the following documents:

• Main text

View BVdb publication page

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Inherited Variation in Cytokine, Acute Phase Response, and Calcium Metabolism Genes Affects Susceptibility to Infective Endocarditis.

Mediators Of Inflammation

AV Ponasenko, AG Kutikhin, MV Khutornaya, NV Rutkovskaya, NV Kondyukova, YN Odarenko, YV Kazachek, AV Tsepokina, LS Barbarash, AE Yuzhalin

Publication Date: 2017

Variant appearance in text: rs6046

PubMed Link: 28659664

Variant Present in the following documents:

• Main text

View BVdb publication page

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Warfarin Dose Model for the Prediction of Stable Maintenance Dose in Indian Patients.

Clinical And Applied Thrombosis/Hemostasis : Official Journal Of The International Academy Of Clinical And Applied Thrombosis/Hemostasis

T Gaikwad, K Ghosh, P Avery, F Kamali, S Shetty

Publication Date: 2018-03

Variant appearance in text: rs6046

PubMed Link: 28049362

Variant Present in the following documents:

• 10.1177_1076029616683046.pdf
• aaaaaMain text
• supplementary_file.pdf

View BVdb publication page

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A Genomics-Based Model for Prediction of Severe Bioprosthetic Mitral Valve Calcification.

International Journal Of Molecular Sciences

AV Ponasenko, MV Khutornaya, AG Kutikhin, NV Rutkovskaya, AV Tsepokina, NV Kondyukova, AE Yuzhalin, LS Barbarash

Publication Date: 2016-08-31

Variant appearance in text: rs6046

PubMed Link: 27589735

Variant Present in the following documents:

• Main text

View BVdb publication page

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Common Genetic Polymorphisms Influence Blood Biomarker Measurements in COPD.

Plos Genetics

W Sun, K Kechris, S Jacobson, MB Drummond, GA Hawkins, J Yang, TH Chen, PM Quibrera, W Anderson, RG Barr, PV Basta, ER Bleecker, T Beaty, R Casaburi, P Castaldi, MH Cho, A Comellas, JD Crapo, G Criner, D Demeo, SA Christenson, DJ Couper, JL Curtis, CM Doerschuk, CM Freeman, NA Gouskova, MK Han, NA Hanania, NN Hansel, CP Hersh, EA Hoffman, RJ Kaner, RE Kanner, EC Kleerup, S Lutz, FJ Martinez, DA Meyers, SP Peters, EA Regan, SI Rennard, MB Scholand, EK Silverman, PG Woodruff, WK O'Neal, RP Bowler, ,

Publication Date: 2016-08

Variant appearance in text: rs6046

PubMed Link: 27532455

Variant Present in the following documents:

• pgen.1006011.s004.xlsx
• pgen.1006011.s008.xls

View BVdb publication page

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Exome-wide Association Study Identifies CLEC3B Missense Variant p.S106G as Being Associated With Extreme Longevity in East Asian Populations.

The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences

K Tanisawa, Y Arai, N Hirose, H Shimokata, Y Yamada, H Kawai, M Kojima, S Obuchi, H Hirano, H Yoshida, H Suzuki, Y Fujiwara, K Ihara, M Sugaya, T Arai, S Mori, M Sawabe, N Sato, M Muramatsu, M Higuchi, YW Liu, QP Kong, M Tanaka

Publication Date: 2017-03-01

Variant appearance in text: rs6046

PubMed Link: 27154906

Variant Present in the following documents:

• glw074_suppl_20160228_jgbs_2015_218r1_supplemantary_tables.xlsx

View BVdb publication page

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The effects of genes implicated in cardiovascular disease on blood pressure response to treatment among treatment-naive hypertensive African Americans in the GenHAT study.

Journal Of Human Hypertension

AN Do, AI Lynch, SA Claas, E Boerwinkle, BR Davis, CE Ford, JH Eckfeldt, HK Tiwari, DK Arnett, MR Irvin

Publication Date: 2016-09

Variant appearance in text: rs6046

PubMed Link: 26791477

Variant Present in the following documents:

• Main text
• NIHMS731953-supplement-2.pdf
• NIHMS731953-supplement-3.pdf

View BVdb publication page

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Can Genetic Analysis of Putative Blood Alzheimer's Disease Biomarkers Lead to Identification of Susceptibility Loci?

Plos One

RC Barber, NR Phillips, JL Tilson, RM Huebinger, SJ Shewale, JL Koenig, JS Mitchel, SE O'Bryant, SC Waring, R Diaz-Arrastia, S Chasse, KC Wilhelmsen, ,

Publication Date: 2015

Variant appearance in text: rs6046

PubMed Link: 26625115

Variant Present in the following documents:

• Main text

View BVdb publication page

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Proinflammatory genotype is associated with the frailty phenotype in the English Longitudinal Study of Ageing.

Aging Clinical And Experimental Research

K Mekli, JY Nazroo, AD Marshall, M Kumari, N Pendleton

Publication Date: 2016-06

Variant appearance in text: rs6046

PubMed Link: 26248682

Variant Present in the following documents:

• 40520_2015_419_MOESM2_ESM.xlsx

View BVdb publication page

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Association of genetic variants with coronary artery disease and ischemic stroke in a longitudinal population-based genetic epidemiological study.

Biomedical Reports

Y Yamada, K Matsui, I Takeuchi, T Fujimaki

Publication Date: 2015-05

Variant appearance in text: rs6046

PubMed Link: 26137247

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association of genetic variants of the α-kinase 1 gene with type 2 diabetes mellitus in a longitudinal population-based genetic epidemiological study.

Biomedical Reports

Y Yamada, K Matsui, I Takeuchi, M Oguri, T Fujimaki

Publication Date: 2015-05

Variant appearance in text: rs6046

PubMed Link: 26137234

Variant Present in the following documents:

• Main text

View BVdb publication page

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Comprehensive gene panels provide advantages over clinical exome sequencing for Mendelian diseases.

Genome Biology

Publication Date: 2015-06-26

Variant appearance in text: rs6046

PubMed Link: 26112015

Variant Present in the following documents:

• 13059_2015_693_MOESM3_ESM.xls

View BVdb publication page

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Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF.

Blood

JE Huffman, PS de Vries, AC Morrison, M Sabater-Lleal, T Kacprowski, PL Auer, JA Brody, DI Chasman, MH Chen, X Guo, LA Lin, RE Marioni, M Müller-Nurasyid, LR Yanek, N Pankratz, ML Grove, MP de Maat, M Cushman, KL Wiggins, L Qi, B Sennblad, SE Harris, O Polasek, H Riess, F Rivadeneira, LM Rose, A Goel, KD Taylor, A Teumer, AG Uitterlinden, D Vaidya, J Yao, W Tang, D Levy, M Waldenberger, DM Becker, AR Folsom, F Giulianini, A Greinacher, A Hofman, CC Huang, C Kooperberg, A Silveira, JM Starr, K Strauch, RJ Strawbridge, AF Wright, B McKnight, OH Franco, N Zakai, RA Mathias, BM Psaty, PM Ridker, GH Tofler, U Völker, H Watkins, M Fornage, A Hamsten, IJ Deary, E Boerwinkle, W Koenig, JI Rotter, C Hayward, A Dehghan, AP Reiner, CJ O'Donnell, NL Smith

Publication Date: 2015-09-10

Variant appearance in text: rs6046

PubMed Link: 26105150

Variant Present in the following documents:

• Main text

View BVdb publication page

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Warfarin dose requirement in Turkish patients: the influences of patient characteristics and polymorphisms in CYP2C9, VKORC1 and factor VII.

Hippokratia

E Yildirim, K Erol, A Birdane

Publication Date: 2014

Variant appearance in text: rs6046

PubMed Link: 26052198

Variant Present in the following documents:

• Main text

View BVdb publication page

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Evidence for Clinical Implementation of Pharmacogenomics in Cardiac Drugs.

Mayo Clinic Proceedings

AL Kaufman, J Spitz, M Jacobs, M Sorrentino, S Yuen, K Danahey, D Saner, TE Klein, RB Altman, MJ Ratain, PH O'Donnell

Publication Date: 2015-06

Variant appearance in text: rs6046

PubMed Link: 26046407

Variant Present in the following documents:

• NIHMS676556-supplement-4.pdf

View BVdb publication page

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Networks in Coronary Heart Disease Genetics As a Step towards Systems Epidemiology.

Plos One

F Drenos, E Grossi, M Buscema, SE Humphries

Publication Date: 2015

Variant appearance in text: rs6046

PubMed Link: 25951190

Variant Present in the following documents:

• Main text
• pone.0125876.s006.xlsx
• pone.0125876.s007.xlsx
• pone.0125876.s008.xlsx

View BVdb publication page

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Association of genetic variants with dyslipidemia and chronic kidney disease in a longitudinal population-based genetic epidemiological study.

International Journal Of Molecular Medicine

Y Yamada, K Matsui, I Takeuchi, T Fujimaki

Publication Date: 2015-05

Variant appearance in text: rs6046

PubMed Link: 25813695

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association of genetic variants with hypertension in a longitudinal population-based genetic epidemiological study.

International Journal Of Molecular Medicine

Y Yamada, K Matsui, I Takeuchi, M Oguri, T Fujimaki

Publication Date: 2015-05

Variant appearance in text: rs6046

PubMed Link: 25813534

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of an interaction between VWF rs7965413 and platelet count as a novel risk marker for metabolic syndrome: an extensive search of candidate polymorphisms in a case-control study.

Plos One

M Nakatochi, Y Ushida, Y Yasuda, Y Yoshida, S Kawai, R Kato, T Nakashima, M Iwata, Y Kuwatsuka, M Ando, N Hamajima, T Kondo, H Oda, M Hayashi, S Kato, M Yamaguchi, S Maruyama, S Matsuo, H Honda

Publication Date: 2015

Variant appearance in text: rs6046

PubMed Link: 25646961

Variant Present in the following documents:

• pone.0117591.s001.docx
• pone.0117591.s002.xlsx
• pone.0117591.s003.xlsx
• pone.0117591.s004.xlsx

View BVdb publication page

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Association of CVD candidate gene polymorphisms with ischemic stroke and cerebral hemorrhage in Chinese individuals.

Plos One

W Ou, X Liu, Y Shen, J Li, L He, Y Yuan, X Tan, L Liu, J Zhao, X Wang

Publication Date: 2014

Variant appearance in text: rs6046

PubMed Link: 25144711

Variant Present in the following documents:

• Main text

View BVdb publication page

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Gene-centric association signals for haemostasis and thrombosis traits identified with the HumanCVD BeadChip.

Thrombosis And Haemostasis

TR Gaunt, D Zabaneh, S Shah, A Guyatt, C Ladroue, M Kumari, F Drenos, T Shah, PJ Talmud, JP Casas, G Lowe, A Rumley, DA Lawlor, M Kivimaki, J Whittaker, AD Hingorani, SE Humphries, IN Day

Publication Date: 2013-11

Variant appearance in text: rs6046

PubMed Link: 24178511

Variant Present in the following documents:

• NIHMS58613-supplement-Supplementary_Data.doc

View BVdb publication page

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Using a multi-staged strategy based on machine learning and mathematical modeling to predict genotype-phenotype risk patterns in diabetic kidney disease: a prospective case-control cohort analysis.

Bmc Nephrology

RK Leung, Y Wang, RC Ma, AO Luk, V Lam, M Ng, WY So, SK Tsui, JC Chan

Publication Date: 2013-07-23

Variant appearance in text: rs6046

PubMed Link: 23879411

Variant Present in the following documents:

• 1471-2369-14-162-S1.doc

View BVdb publication page

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Ischemic stroke is associated with the ABO locus: the EuroCLOT study.

Annals Of Neurology

FM Williams, AM Carter, PG Hysi, G Surdulescu, D Hodgkiss, N Soranzo, M Traylor, S Bevan, M Dichgans, PM Rothwell, C Sudlow, M Farrall, K Silander, M Kaunisto, P Wagner, O Saarela, K Kuulasmaa, J Virtamo, V Salomaa, P Amouyel, D Arveiler, J Ferrieres, PG Wiklund, MA Ikram, A Hofman, GB Boncoraglio, EA Parati, A Helgadottir, S Gretarsdottir, U Thorsteinsdottir, G Thorleifsson, K Stefansson, S Seshadri, A DeStefano, A Gschwendtner, B Psaty, W Longstreth, BD Mitchell, YC Cheng, R Clarke, M Ferrario, JC Bis, C Levi, J Attia, EG Holliday, RJ Scott, M Fornage, P Sharma, KL Furie, J Rosand, M Nalls, J Meschia, TH Mosely, A Evans, A Palotie, HS Markus, PJ Grant, TD Spector, , , , ,

Publication Date: 2013-01

Variant appearance in text: rs6046

PubMed Link: 23381943

Variant Present in the following documents:

• ana0073-0016-SD1.doc

View BVdb publication page

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Epistatic study reveals two genetic interactions in blood pressure regulation.

Bmc Medical Genetics

NC Ndiaye, el S Said, MG Stathopoulou, G Siest, MY Tsai, S Visvikis-Siest

Publication Date: 2013-01-08

Variant appearance in text: rs6046

PubMed Link: 23298194

Variant Present in the following documents:

• 1471-2350-14-2-S1.doc
• aaaaaMain text

View BVdb publication page

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Personalized approach of medication by indirect anticoagulants tailored to the patient-Russian context: what are the prospects?

The Epma Journal

LA Belozerceva, EN Voronina, NV Kokh, GA Tsvetovskay, AP Momot, GI Lifshits, ML Filipenko, AI Shevela, VV Vlasov

Publication Date: 2012-09-27

Variant appearance in text: rs6046

PubMed Link: 23016735

Variant Present in the following documents:

• Main text

View BVdb publication page

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Functional epistatic interaction between rs6046G>A in F7 and rs5355C>T in SELE modifies systolic blood pressure levels.

Plos One

S El Shamieh, NC Ndiaye, MG Stathopoulou, HA Murray, C Masson, JV Lamont, P Fitzgerald, A Benetos, S Visvikis-Siest

Publication Date: 2012

Variant appearance in text: rs6046

PubMed Link: 22815813

Variant Present in the following documents:

• Main text
• pone.0040777.s001.doc

View BVdb publication page

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Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.

American Journal Of Human Genetics

W Tang, C Schwienbacher, LM Lopez, Y Ben-Shlomo, T Oudot-Mellakh, AD Johnson, NJ Samani, S Basu, M Gögele, G Davies, GD Lowe, DA Tregouet, A Tan, JS Pankow, A Tenesa, D Levy, CB Volpato, A Rumley, AJ Gow, C Minelli, JW Yarnell, DJ Porteous, JM Starr, J Gallacher, E Boerwinkle, PM Visscher, PP Pramstaller, M Cushman, V Emilsson, AS Plump, N Matijevic, PE Morange, IJ Deary, AA Hicks, AR Folsom

Publication Date: 2012-07-13

Variant appearance in text: rs6046

PubMed Link: 22703881

Variant Present in the following documents:

• Main text
• mmc1.pdf
• mmc2.xlsx

View BVdb publication page

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A Database of Gene-Environment Interactions Pertaining to Blood Lipid Traits, Cardiovascular Disease and Type 2 Diabetes.

Journal Of Data Mining In Genomics & Proteomics

YC Lee, CQ Lai, JM Ordovas, LD Parnell

Publication Date: 2011-01-01

Variant appearance in text: rs6046

PubMed Link: 22328972

Variant Present in the following documents:

• NIHMS285264-supplement-Supplementary_Tables.xls

View BVdb publication page

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Large-scale gene-centric analysis identifies novel variants for coronary artery disease.

Plos Genetics

Publication Date: 2011-09

Variant appearance in text: rs6046

PubMed Link: 21966275

Variant Present in the following documents:

• pgen.1002260.s008.pdf

View BVdb publication page

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Relationships of plasma factor VIIa-antithrombin complexes to manifest and future cardiovascular disease.

Thrombosis Research

A Silveira, D Scanavini, S Boquist, CG Ericsson, ML Hellénius, K Leander, U de Faire, J Ohrvik, B Woodhams, JH Morrissey, A Hamsten

Publication Date: 2012-08

Variant appearance in text: rs6046

PubMed Link: 21925715

Variant Present in the following documents:

• Main text

View BVdb publication page

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Multilocus association testing with penalized regression.

Genetic Epidemiology

S Basu, W Pan, X Shen, WS Oetting

Publication Date: 2011-12

Variant appearance in text: rs6046

PubMed Link: 21922539

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic variants and susceptibility to neurological complications following West Nile virus infection.

The Journal Of Infectious Diseases

M Loeb, S Eskandarian, M Rupp, N Fishman, L Gasink, J Patterson, J Bramson, TJ Hudson, M Lemire

Publication Date: 2011-10-01

Variant appearance in text: rs6046

PubMed Link: 21881118

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association between polymorphisms in the coagulation factor VII gene and coronary heart disease risk in different ethnicities: a meta-analysis.

Bmc Medical Genetics

X Mo, Y Hao, X Yang, S Chen, X Lu, D Gu

Publication Date: 2011-08-12

Variant appearance in text: rs6046

PubMed Link: 21838885

Variant Present in the following documents:

• Main text

View BVdb publication page

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A gene-centric association scan for Coagulation Factor VII levels in European and African Americans: the Candidate Gene Association Resource (CARe) Consortium.

Human Molecular Genetics

KC Taylor, LA Lange, D Zabaneh, E Lange, BJ Keating, W Tang, NL Smith, JA Delaney, M Kumari, A Hingorani, KE North, M Kivimaki, RP Tracy, CJ O'Donnell, AR Folsom, D Green, SE Humphries, AP Reiner

Publication Date: 2011-09-01

Variant appearance in text: rs6046

PubMed Link: 21676895

Variant Present in the following documents:

• Main text

View BVdb publication page

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Heterogeneity of the phenotypic definition of coronary artery disease and its impact on genetic association studies.

Circulation. Cardiovascular Genetics

GD Kitsios, IJ Dahabreh, TA Trikalinos, CH Schmid, GS Huggins, DM Kent

Publication Date: 2011-02

Variant appearance in text: rs6046

PubMed Link: 21149552

Variant Present in the following documents:

• NIHMS265927-supplement-1.pdf

View BVdb publication page

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Association of coagulation-related and inflammation-related genes and factor VIIc levels with stroke: the Cardiovascular Health Study.

Journal Of Thrombosis And Haemostasis : Jth

NA Zakai, L Lange, WT Longstreth, ES O'Meara, JL Kelley, M Fornage, D Nikerson, M Cushman, AP Reiner

Publication Date: 2011-02

Variant appearance in text: rs6046

PubMed Link: 21114618

Variant Present in the following documents:

• Main text
• NIHMS253450-supplement-Table_S1.doc
• NIHMS253450-supplement-Table_S2_and_S3.doc

View BVdb publication page

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Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men.

Journal Of Thrombosis And Haemostasis : Jth

G Ken-Dror, F Drenos, SE Humphries, PJ Talmud, AD Hingorani, M Kivimäki, M Kumari, KA Bauer, JH Morrissey, HA Ireland

Publication Date: 2010-11

Variant appearance in text: rs6046

PubMed Link: 20735728

Variant Present in the following documents:

• Main text
• NIHMS280652-supplement-Supp_Table_S1-_S4.doc

View BVdb publication page

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Association of fetal inflammation and coagulation pathway gene polymorphisms with neurodevelopmental delay at age 2 years.

American Journal Of Obstetrics And Gynecology

EA Clark, L Mele, RJ Wapner, CY Spong, Y Sorokin, A Peaceman, JD Iams, KJ Leveno, M Harper, SN Caritis, M Miodovnik, BM Mercer, JM Thorp, SM Ramin, M Carpenter, DJ Rouse,

Publication Date: 2010-07

Variant appearance in text: rs6046

PubMed Link: 20417488

Variant Present in the following documents:

• Main text

View BVdb publication page

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Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth.

Plos One

KK Ryckman, NH Morken, MJ White, DR Velez, R Menon, SJ Fortunato, P Magnus, SM Williams, B Jacobsson

Publication Date: 2010-02-03

Variant appearance in text: rs6046

PubMed Link: 20140262

Variant Present in the following documents:

• pone.0009040.s003.doc

View BVdb publication page

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Genetics of atherothrombotic and lacunar stroke.

Circulation. Cardiovascular Genetics

S Debette, S Seshadri

Publication Date: 2009-04

Variant appearance in text: rs6046

PubMed Link: 20031584

Variant Present in the following documents:

• NIHMS126592-supplement-1.pdf

View BVdb publication page

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An evaluation of candidate genes of inflammation and thrombosis in relation to the risk of venous thromboembolism: The Women's Genome Health Study.

Circulation. Cardiovascular Genetics

RY Zee, RJ Glynn, S Cheng, L Steiner, L Rose, PM Ridker

Publication Date: 2009-02

Variant appearance in text: rs6046

PubMed Link: 20031567

Variant Present in the following documents:

• Main text
• NIHMS104124-supplement-Suppl_tables.doc

View BVdb publication page

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Association of congenital cardiovascular malformations with 33 single nucleotide polymorphisms of selected cardiovascular disease-related genes.

Birth Defects Research. Part A, Clinical And Molecular Teratology

K Kuehl, C Loffredo, EJ Lammer, DM Iovannisci, GM Shaw

Publication Date: 2010-02

Variant appearance in text: rs6046

PubMed Link: 19764075

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic and environmental factors determining clinical outcomes and cost of warfarin therapy: a prospective study.

Pharmacogenetics And Genomics

AL Jorgensen, S Al-Zubiedi, JE Zhang, A Keniry, A Hanson, DA Hughes, Dv Eker, L Stevens, K Hawkins, CH Toh, F Kamali, AK Daly, D Fitzmaurice, A Coffey, PR Williamson, BK Park, P Deloukas, M Pirmohamed

Publication Date: 2009-10

Variant appearance in text: rs6046

PubMed Link: 19752777

Variant Present in the following documents:

• NIHMS30438-supplement-Supplementary_Table_B.doc

View BVdb publication page

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Association of genetic variants with the metabolic syndrome in 20,806 white women: The Women's Health Genome Study.

American Heart Journal

AC Goulart, KM Rexrode, S Cheng, L Rose, JE Buring, PM Ridker, RY Zee

Publication Date: 2009-08

Variant appearance in text: rs6046

PubMed Link: 19619703

Variant Present in the following documents:

• NIHMS140113-supplement-Supple.doc

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A candidate gene association study of 77 polymorphisms in migraine.

The Journal Of Pain : Official Journal Of The American Pain Society

M Schürks, T Kurth, JE Buring, RY Zee

Publication Date: 2009-07

Variant appearance in text: rs6046

PubMed Link: 19559392

Variant Present in the following documents:

• Main text

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Common hemostasis and inflammation gene variants and venous thrombosis in older adults from the Cardiovascular Health Study.

Journal Of Thrombosis And Haemostasis : Jth

AP Reiner, LA Lange, NL Smith, NA Zakai, M Cushman, AR Folsom

Publication Date: 2009-09

Variant appearance in text: rs6046

PubMed Link: 19552680

Variant Present in the following documents:

• NIHMS168993-supplement-Supplemental_Table_2.doc

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Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.

Proceedings Of The National Academy Of Sciences Of The United States Of America

LA Hindorff, P Sethupathy, HA Junkins, EM Ramos, JP Mehta, FS Collins, TA Manolio

Publication Date: 2009-06-09

Variant appearance in text: rs6046

PubMed Link: 19474294

Variant Present in the following documents:

• Main text

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The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13 ) on the effectiveness of statins: the GenHAT study.

Pharmacogenetics And Genomics

AH Maitland-van der Zee, BJ Peters, AI Lynch, E Boerwinkle, DK Arnett, S Cheng, BR Davis, C Leiendecker-Foster, CE Ford, JH Eckfeldt

Publication Date: 2009-05

Variant appearance in text: rs6046

PubMed Link: 19415820

Variant Present in the following documents:

• Main text

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Complexity in the genetic architecture of leukoaraiosis in hypertensive sibships from the GENOA Study.

Bmc Medical Genomics

JA Smith, ST Turner, YV Sun, M Fornage, RJ Kelly, TH Mosley, CR Jack, IJ Kullo, SL Kardia

Publication Date: 2009-04-07

Variant appearance in text: rs6046

PubMed Link: 19351393

Variant Present in the following documents:

• 1755-8794-2-16-S1.xls

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Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk.

Human Molecular Genetics

F Drenos, PJ Talmud, JP Casas, L Smeeth, J Palmen, SE Humphries, AD Hingorani

Publication Date: 2009-06-15

Variant appearance in text: rs6046

PubMed Link: 19336475

Variant Present in the following documents:

• Main text

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Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study.

Journal Of Hypertension

D Conen, S Cheng, LL Steiner, JE Buring, PM Ridker, RY Zee

Publication Date: 2009-03

Variant appearance in text: rs6046

PubMed Link: 19330901

Variant Present in the following documents:

• Main text

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Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach.

Clinica Chimica Acta; International Journal Of Clinical Chemistry

RY Zee, V Bubes, S Shrivastava, PM Ridker, RJ Glynn

Publication Date: 2009-04

Variant appearance in text: rs6046

PubMed Link: 19263529

Variant Present in the following documents:

• Main text
• NIHMS91649-supplement-01.doc

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A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.

Stroke

X Wang, S Cheng, VH Brophy, HA Erlich, C Mannhalter, K Berger, W Lalouschek, WS Browner, Y Shi, EB Ringelstein, C Kessler, J Luedemann, K Lindpaintner, L Liu, PM Ridker, RY Zee, NR Cook,

Publication Date: 2009-03

Variant appearance in text: rs6046

PubMed Link: 19131662

Variant Present in the following documents:

• Main text

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Gender differences in genetic risk profiles for cardiovascular disease.

Plos One

K Silander, M Alanne, K Kristiansson, O Saarela, S Ripatti, K Auro, J Karvanen, S Kulathinal, M Niemelä, P Ellonen, E Vartiainen, P Jousilahti, J Saarela, K Kuulasmaa, A Evans, M Perola, V Salomaa, L Peltonen

Publication Date: 2008

Variant appearance in text: rs6046

PubMed Link: 18974842

Variant Present in the following documents:

• pone.0003615.s001.xls

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New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background.

Bmc Bioinformatics

S Penco, M Buscema, MC Patrosso, A Marocchi, E Grossi

Publication Date: 2008-05-30

Variant appearance in text: rs6046

PubMed Link: 18513389

Variant Present in the following documents:

• Main text

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Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study.

Bmc Medical Genetics

Q Yang, S Kathiresan, JP Lin, GH Tofler, CJ O'Donnell

Publication Date: 2007-09-19

Variant appearance in text: rs6046

PubMed Link: 17903294

Variant Present in the following documents:

• Main text

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Alternative transcript annotations:

Transcript	cDNA	Protein	Consequence	Exon	Intron
ENST00000346342.3	c.1172G>C	p.Arg391Pro	missense_variant	8/8	-
ENST00000375581.3	c.1238G>C	p.Arg413Pro	missense_variant	9/9	-
ENST00000541084.1	c.1031G>C	p.Arg344Pro	missense_variant	6/6	-
NM_000131.4	c.1238G>C	p.Arg413Pro	missense_variant	9/9	-
NM_001267554.1	c.986G>C	p.Arg329Pro	missense_variant	6/6	-
NM_019616.3	c.1172G>C	p.Arg391Pro	missense_variant	8/8	-
NR_051961.2	n.1256G>C	-	non_coding_transcript_exon_variant	7/7	-