Publications:

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Multi-omics analysis defines highly refractory RAS burdened immature subgroup of infant acute lymphoblastic leukemia.

Nature Communications

Isobe, Tomoya T; Takagi, Masatoshi M; Sato-Otsubo, Aiko A; Nishimura, Akira A; Nagae, Genta G; Yamagishi, Chika C; Tamura, Moe M; Tanaka, Yosuke Y; Asada, Shuhei S; Takeda, Reina R; Tsuchiya, Akiho A; Wang, Xiaonan X; Yoshida, Kenichi K; Nannya, Yasuhito Y; Ueno, Hiroo H; Akazawa, Ryo R; Kato, Itaru I; Mikami, Takashi T; Watanabe, Kentaro K; Sekiguchi, Masahiro M; Seki, Masafumi M; Kimura, Shunsuke S; Hiwatari, Mitsuteru M; Kato, Motohiro M; Fukuda, Shiro S; Tatsuno, Kenji K; Tsutsumi, Shuichi S; Kanai, Akinori A; Inaba, Toshiya T; Shiozawa, Yusuke Y; Shiraishi, Yuichi Y; Chiba, Kenichi K; Tanaka, Hiroko H; Kotecha, Rishi S RS; Cruickshank, Mark N MN; Ishikawa, Fumihiko F; Morio, Tomohiro T; Eguchi, Mariko M; Deguchi, Takao T; Kiyokawa, Nobutaka N; Arakawa, Yuki Y; Koh, Katsuyoshi K; Aoki, Yuki Y; Ishihara, Takashi T; Tomizawa, Daisuke D; Miyamura, Takako T; Ishii, Eiichi E; Mizutani, Shuki S; Wilson, Nicola K NK; Göttgens, Berthold B; Miyano, Satoru S; Kitamura, Toshio T; Goyama, Susumu S; Yokoyama, Akihiko A; Aburatani, Hiroyuki H; Ogawa, Seishi S; Takita, Junko J

Publication Date: 2022-08-30

Variant appearance in text: FLT3: 2503_2505del

PubMed Link: 36042201

Variant Present in the following documents:

• 41467_2022_32266_MOESM12_ESM.xlsx, sheet 1

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: FLT3: 2503_2505delGAT; D835del

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Selectively targeting FLT3-ITD mutants over FLT3-wt by a novel inhibitor for acute myeloid leukemia.

Haematologica

Wang, Aoli A; Hu, Chen C; Chen, Cheng C; Liang, Xiaofei X; Wang, Beilei B; Zou, Fengming F; Yu, Kailin K; Li, Feng F; Liu, Qingwang Q; Qi, Ziping Z; Wang, Junjie J; Wang, Wenliang W; Wang, Li L; Weisberg, Ellen L EL; Wang, Wenchao W; Li, Lili L; Ge, Jian J; Xia, Ruixiang R; Liu, Jing J; Liu, Qingsong Q

Publication Date: 2021-02-01

Variant appearance in text: FLT3: D835del

PubMed Link: 32299905

Variant Present in the following documents:

• 2019_244186_WANG_SUPPL.pdf

View BVdb publication page

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High incidence of FLT3 mutations in follicular thyroid cancer: potential therapeutic target in patients with advanced disease stage.

Therapeutic Advances In Medical Oncology

Borowczyk, Martyna M; Szczepanek-Parulska, Ewelina E; Dębicki, Szymon S; Budny, Bartłomiej B; Janicka-Jedyńska, Małgorzata M; Gil, Lidia L; Verburg, Frederik A FA; Filipowicz, Dorota D; Wrotkowska, Elżbieta E; Majchrzycka, Blanka B; Marszałek, Andrzej A; Ziemnicka, Katarzyna K; Ruchała, Marek M

Publication Date: 2020

Variant appearance in text: FLT3: 2503_2505delGAT; rs121913486

PubMed Link: 32180839

Variant Present in the following documents:

• Main text

View BVdb publication page

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Comprehensive diagnostics of acute myeloid leukemia by whole transcriptome RNA sequencing.

Leukemia

Arindrarto, Wibowo W; Borràs, Daniel M DM; de Groen, Ruben A L RAL; van den Berg, Redmar R RR; Locher, Irene J IJ; van Diessen, Saskia A M E SAME; van der Holst, Rosalie R; van der Meijden, Edith D ED; Honders, M Willy MW; de Leeuw, Rick H RH; Verlaat, Wina W; Jedema, Inge I; Kroes, Wilma G M WGM; Knijnenburg, Jeroen J; van Wezel, Tom T; Vermaat, Joost S P JSP; Valk, Peter J M PJM; Janssen, Bart B; de Knijff, Peter P; van Bergen, Cornelis A M CAM; van den Akker, Erik B EB; Hoen, Peter A C 't PAC'; Kiełbasa, Szymon M SM; Laros, Jeroen F J JFJ; Griffioen, Marieke M; Veelken, Hendrik H

Publication Date: 2021-01

Variant appearance in text: FLT3: 2503_2505del; Asp835del; rs121913486

PubMed Link: 32127641

Variant Present in the following documents:

• 41375_2020_762_MOESM1_ESM.pdf

View BVdb publication page

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Resistance to FLT3 inhibitors in acute myeloid leukemia: Molecular mechanisms and resensitizing strategies.

World Journal Of Clinical Oncology

Zhou, Jianbiao J; Chng, Wee-Joo WJ

Publication Date: 2018-09-14

Variant appearance in text: FLT3: D835del

PubMed Link: 30254964

Variant Present in the following documents:

• Main text
• WJCO-9-90.pdf

View BVdb publication page

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Fibroblast growth factor receptor 3 (FGFR3) aberrations in muscle-invasive urothelial carcinoma.

Bmc Urology

Kim, Young Saing YS; Kim, Kyung K; Kwon, Ghee-Young GY; Lee, Su Jin SJ; Park, Se Hoon SH

Publication Date: 2018-07-31

Variant appearance in text: FLT3: 2503_2505delGAT; D835del

PubMed Link: 30064409

Variant Present in the following documents:

• 12894_2018_380_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Feasibility study of cancer genome alterations identified by next generation sequencing: ABC study.

Japanese Journal Of Clinical Oncology

Naito, Yoichi Y; Takahashi, Hideaki H; Shitara, Kohei K; Okamoto, Wataru W; Bando, Hideaki H; Kuwata, Takeshi T; Kuboki, Yasutoshi Y; Matsumoto, Shingo S; Miki, Izumi I; Yamanaka, Takeharu T; Watanabe, Atsushi A; Kojima, Motohiro M

Publication Date: 2018-06-01

Variant appearance in text: FLT3: 2503_2505delGAT; D835del

PubMed Link: 29659903

Variant Present in the following documents:

• hyy052supplementaltable1ionver1.xls, sheet 1

View BVdb publication page

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The sorafenib anti-relapse effect after alloHSCT is associated with heightened alloreactivity and accumulation of CD8+PD-1+ (CD279+) lymphocytes in marrow.

Plos One

Lange, Andrzej A; Jaskula, Emilia E; Lange, Janusz J; Dworacki, Grzegorz G; Nowak, Dorota D; Simiczyjew, Aleksandra A; Mordak-Domagala, Monika M; Sedzimirska, Mariola M

Publication Date: 2018

Variant appearance in text: FLT3: 2503_2505delGAT; D835del

PubMed Link: 29304116

Variant Present in the following documents:

• pone.0190525.s001.xlsx, sheet 1

View BVdb publication page

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Proximal Aberrant Crypt Foci Associate with Synchronous Neoplasia and Are Primed for Neoplastic Progression.

Molecular Cancer Research : Mcr

Drew, David A DA; Mo, Allen A; Grady, James J JJ; Stevens, Richard G RG; Levine, Joel B JB; Brenner, Bruce M BM; Anderson, Joseph C JC; Forouhar, Faripour F; O'Brien, Michael J MJ; Devers, Thomas J TJ; Rosenberg, Daniel W DW

Publication Date: 2018-03

Variant appearance in text: FLT3: D835del

PubMed Link: 29222172

Variant Present in the following documents:

• Main text

View BVdb publication page

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Molecular Characterization of Urothelial Carcinoma of the Bladder and Upper Urinary Tract.

Translational Oncology

Lee, Ji Yun JY; Kim, Kyung K; Sung, Hyun Hwan HH; Jeon, Hwang Gyun HG; Jeong, Byong Chang BC; Seo, Seong Il SI; Jeon, Seong Soo SS; Lee, Hyun Moo HM; Choi, Han-Yong HY; Kwon, Ghee-Young GY; Kim, Kyoung-Mee KM; Lee, Jeeyun J; Lim, Ho Yeong HY; Park, Se Hoon SH

Publication Date: 2018-02

Variant appearance in text: FLT3: 2503_2505delGAT; D835del

PubMed Link: 29161613

Variant Present in the following documents:

• mmc1.xlsx, sheet 1

View BVdb publication page

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Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo.

Leukemia

Chaturvedi, A A; Herbst, L L; Pusch, S S; Klett, L L; Goparaju, R R; Stichel, D D; Kaulfuss, S S; Panknin, O O; Zimmermann, K K; Toschi, L L; Neuhaus, R R; Haegebarth, A A; Rehwinkel, H H; Hess-Stumpp, H H; Bauser, M M; Bochtler, T T; Struys, E A EA; Sharma, A A; Bakkali, A A; Geffers, R R; Araujo-Cruz, M M MM; Thol, F F; Gabdoulline, R R; Ganser, A A; Ho, A D AD; von Deimling, A A; Rippe, K K; Heuser, M M; Krämer, A A

Publication Date: 2017-10

Variant appearance in text: FLT3: D835del

PubMed Link: 28232670

Variant Present in the following documents:

• Main text
• leu201746a.pdf

View BVdb publication page

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Mutational profiling of brain metastasis from breast cancer: matched pair analysis of targeted sequencing between brain metastasis and primary breast cancer.

Oncotarget

Lee, Ji Yun JY; Park, Kyunghee K; Lim, Sung Hee SH; Kim, Hae Su HS; Yoo, Kwai Han KH; Jung, Ki Sun KS; Song, Haa-Na HN; Hong, Mineui M; Do, In-Gu IG; Ahn, TaeJin T; Lee, Se Kyung SK; Bae, Soo Youn SY; Kim, Seok Won SW; Lee, Jeong Eon JE; Nam, Seok Jin SJ; Kim, Duk-Hwan DH; Jung, Hae Hyun HH; Kim, Ji-Yeon JY; Ahn, Jin Seok JS; Im, Young-Hyuck YH; Park, Yeon Hee YH

Publication Date: 2015-12-22

Variant appearance in text: FLT3: 2503_2505delGAT; D835del

PubMed Link: 26527317

Variant Present in the following documents:

• oncotarget-06-43731-s002.xlsx, sheet 1

View BVdb publication page

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Patient-derived cell models as preclinical tools for genome-directed targeted therapy.

Oncotarget

Lee, Ji Yun JY; Kim, Sun Young SY; Park, Charny C; Kim, Nayoung K D NK; Jang, Jiryeon J; Park, Kyunghee K; Yi, Jun Ho JH; Hong, Mineui M; Ahn, Taejin T; Rath, Oliver O; Schueler, Julia J; Kim, Seung Tae ST; Do, In-Gu IG; Lee, Sujin S; Park, Se Hoon SH; Ji, Yong Ick YI; Kim, Dukwhan D; Park, Joon Oh JO; Park, Young Suk YS; Kang, Won Ki WK; Kim, Kyoung-Mee KM; Park, Woong-Yang WY; Lim, Ho Yeong HY; Lee, Jeeyun J

Publication Date: 2015-09-22

Variant appearance in text: FLT3: 2503_2505delGAT; D835del

PubMed Link: 26296973

Variant Present in the following documents:

• oncotarget-06-25619-s003.xls, sheet 1

View BVdb publication page

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Molecular characterization of patients with pathologic complete response or early failure after neoadjuvant chemotherapy for locally advanced breast cancer using next generation sequencing and nCounter assay.

Oncotarget

Park, Kyunghee K; Choi, Moon Ki MK; Jung, Hae Hyun HH; Do, In-Gu IG; Lee, Kwang Hee KH; Ahn, TaeJin T; Kil, Won Ho WH; Kim, Seok Won SW; Lee, Jeong Eon JE; Nam, Seok Jin SJ; Kim, Duk-Hwan DH; Ahn, Jin Seok JS; Im, Young-Hyuck YH; Park, Yeon Hee YH

Publication Date: 2015-09-15

Variant appearance in text: FLT3: 2503_2505delGAT; D835del

PubMed Link: 26009992

Variant Present in the following documents:

• oncotarget-06-24499-s002.xlsx, sheet 1

View BVdb publication page

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High-throughput sequencing and copy number variation detection using formalin fixed embedded tissue in metastatic gastric cancer.

Plos One

Kim, Seokhwi S; Lee, Jeeyun J; Hong, Min Eui ME; Do, In-Gu IG; Kang, So Young SY; Ha, Sang Yun SY; Kim, Seung Tae ST; Park, Se Hoon SH; Kang, Won Ki WK; Choi, Min-Gew MG; Lee, Jun Ho JH; Sohn, Tae Sung TS; Bae, Jae Moon JM; Kim, Sung S; Kim, Duk-Hwan DH; Kim, Kyoung-Mee KM

Publication Date: 2014

Variant appearance in text: FLT3: 2503_2505delGAT; D835del

PubMed Link: 25372287

Variant Present in the following documents:

• pone.0111693.s003.xls, sheet 1

View BVdb publication page

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Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

The Journal Of Molecular Diagnostics : Jmd

MacConaill, Laura E LE; Garcia, Elizabeth E; Shivdasani, Priyanka P; Ducar, Matthew M; Adusumilli, Ravali R; Breneiser, Marc M; Byrne, Mark M; Chung, Lawrence L; Conneely, Jodie J; Crosby, Lauren L; Garraway, Levi A LA; Gong, Xin X; Hahn, William C WC; Hatton, Charlie C; Kantoff, Philip W PW; Kluk, Michael M; Kuo, Frank F; Jia, Yonghui Y; Joshi, Ruchi R; Longtine, Janina J; Manning, Allison A; Palescandolo, Emanuele E; Sharaf, Nematullah N; Sholl, Lynette L; van Hummelen, Paul P; Wade, Jacqueline J; Wollinson, Bruce M BM; Zepf, Dimity D; Rollins, Barrett J BJ; Lindeman, Neal I NI

Publication Date: 2014-11

Variant appearance in text: FLT3: D835del

PubMed Link: 25157968

Variant Present in the following documents:

• Main text

View BVdb publication page

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.

Nature

Barretina, Jordi J; Caponigro, Giordano G; Stransky, Nicolas N; Venkatesan, Kavitha K; Margolin, Adam A AA; Kim, Sungjoon S; Wilson, Christopher J CJ; Lehár, Joseph J; Kryukov, Gregory V GV; Sonkin, Dmitriy D; Reddy, Anupama A; Liu, Manway M; Murray, Lauren L; Berger, Michael F MF; Monahan, John E JE; Morais, Paula P; Meltzer, Jodi J; Korejwa, Adam A; Jané-Valbuena, Judit J; Mapa, Felipa A FA; Thibault, Joseph J; Bric-Furlong, Eva E; Raman, Pichai P; Shipway, Aaron A; Engels, Ingo H IH; Cheng, Jill J; Yu, Guoying K GK; Yu, Jianjun J; Aspesi, Peter P; de Silva, Melanie M; Jagtap, Kalpana K; Jones, Michael D MD; Wang, Li L; Hatton, Charles C; Palescandolo, Emanuele E; Gupta, Supriya S; Mahan, Scott S; Sougnez, Carrie C; Onofrio, Robert C RC; Liefeld, Ted T; MacConaill, Laura L; Winckler, Wendy W; Reich, Michael M; Li, Nanxin N; Mesirov, Jill P JP; Gabriel, Stacey B SB; Getz, Gad G; Ardlie, Kristin K; Chan, Vivien V; Myer, Vic E VE; Weber, Barbara L BL; Porter, Jeff J; Warmuth, Markus M; Finan, Peter P; Harris, Jennifer L JL; Meyerson, Matthew M; Golub, Todd R TR; Morrissey, Michael P MP; Sellers, William R WR; Schlegel, Robert R; Garraway, Levi A LA

Publication Date: 2012-03-28

Variant appearance in text: FLT3: 2503_2505delGAT; D835del

PubMed Link: 22460905

Variant Present in the following documents:

• NIHMS361223-supplement-4.xlsx, sheet 3

View BVdb publication page

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Profiling critical cancer gene mutations in clinical tumor samples.

Plos One

MacConaill, Laura E LE; Campbell, Catarina D CD; Kehoe, Sarah M SM; Bass, Adam J AJ; Hatton, Charles C; Niu, Lili L; Davis, Matt M; Yao, Keluo K; Hanna, Megan M; Mondal, Chandrani C; Luongo, Lauren L; Emery, Caroline M CM; Baker, Alissa C AC; Philips, Juliet J; Goff, Deborah J DJ; Fiorentino, Michelangelo M; Rubin, Mark A MA; Polyak, Kornelia K; Chan, Jennifer J; Wang, Yuexiang Y; Fletcher, Jonathan A JA; Santagata, Sandro S; Corso, Gianni G; Roviello, Franco F; Shivdasani, Ramesh R; Kieran, Mark W MW; Ligon, Keith L KL; Stiles, Charles D CD; Hahn, William C WC; Meyerson, Matthew L ML; Garraway, Levi A LA

Publication Date: 2009-11-18

Variant appearance in text: FLT3: D835del

PubMed Link: 19924296

Variant Present in the following documents:

• pone.0007887.s002.xls, sheet 1

View BVdb publication page

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