Publications:

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The IL-3, IL-5, and GM-CSF common receptor beta chain mediates oncogenic activity of FLT3-ITD-positive AML.

Leukemia

Charlet, Anne A; Kappenstein, Max M; Keye, Philip P; Kläsener, Kathrin K; Endres, Cornelia C; Poggio, Teresa T; Gorantla, Sivahari P SP; Kreutmair, Stefanie S; Sänger, Jana J; Illert, Anna L AL; Miething, Cornelius C; Reth, Michael M; Duyster, Justus J; Rummelt, Christoph C; von Bubnoff, Nikolas N

Publication Date: 2022-03

Variant appearance in text: FLT3: K602R

PubMed Link: 34750506

Variant Present in the following documents:

• 41375_2021_Article_1462.pdf

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Effective Treatment With Afatinib of Lung Adenocarcinoma With Leptomeningeal Metastasis Harboring the Exon 18 p.G719A Mutation in the EGFR Gene Was Detected in Cerebrospinal Fluid: A Case Report.

Frontiers In Oncology

Ma, Chunhua C; Wang, Shuyuan S; Mu, Ning N; Li, Jinduo J; Liu, Mei M; Li, Lin L; Jiang, Rong R

Publication Date: 2020

Variant appearance in text: FLT3: K602R

PubMed Link: 33014823

Variant Present in the following documents:

• Main text
• fonc-10-01635.pdf

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High incidence of FLT3 mutations in follicular thyroid cancer: potential therapeutic target in patients with advanced disease stage.

Therapeutic Advances In Medical Oncology

Borowczyk, Martyna M; Szczepanek-Parulska, Ewelina E; Dębicki, Szymon S; Budny, Bartłomiej B; Janicka-Jedyńska, Małgorzata M; Gil, Lidia L; Verburg, Frederik A FA; Filipowicz, Dorota D; Wrotkowska, Elżbieta E; Majchrzycka, Blanka B; Marszałek, Andrzej A; Ziemnicka, Katarzyna K; Ruchała, Marek M

Publication Date: 2020

Variant appearance in text: FLT3: 1805A>G

PubMed Link: 32180839

Variant Present in the following documents:

• Main text
• 10.1177_1758835920907534.pdf

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The target landscape of clinical kinase drugs.

Science (New York, N.Y.)

Klaeger, Susan S; Heinzlmeir, Stephanie S; Wilhelm, Mathias M; Polzer, Harald H; Vick, Binje B; Koenig, Paul-Albert PA; Reinecke, Maria M; Ruprecht, Benjamin B; Petzoldt, Svenja S; Meng, Chen C; Zecha, Jana J; Reiter, Katrin K; Qiao, Huichao H; Helm, Dominic D; Koch, Heiner H; Schoof, Melanie M; Canevari, Giulia G; Casale, Elena E; Depaolini, Stefania Re SR; Feuchtinger, Annette A; Wu, Zhixiang Z; Schmidt, Tobias T; Rueckert, Lars L; Becker, Wilhelm W; Huenges, Jan J; Garz, Anne-Kathrin AK; Gohlke, Bjoern-Oliver BO; Zolg, Daniel Paul DP; Kayser, Gian G; Vooder, Tonu T; Preissner, Robert R; Hahne, Hannes H; Tõnisson, Neeme N; Kramer, Karl K; Götze, Katharina K; Bassermann, Florian F; Schlegl, Judith J; Ehrlich, Hans-Christian HC; Aiche, Stephan S; Walch, Axel A; Greif, Philipp A PA; Schneider, Sabine S; Felder, Eduard Rudolf ER; Ruland, Juergen J; Médard, Guillaume G; Jeremias, Irmela I; Spiekermann, Karsten K; Kuster, Bernhard B

Publication Date: 2017-12-01

Variant appearance in text: FLT3: K602R

PubMed Link: 29191878

Variant Present in the following documents:

• Main text

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Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia.

Leukemia

Reiter, K K; Polzer, H H; Krupka, C C; Maiser, A A; Vick, B B; Rothenberg-Thurley, M M; Metzeler, K H KH; Dörfel, D D; Salih, H R HR; Jung, G G; Nößner, E E; Jeremias, I I; Hiddemann, W W; Leonhardt, H H; Spiekermann, K K; Subklewe, M M; Greif, P A PA

Publication Date: 2018-02

Variant appearance in text: FLT3: K602R

PubMed Link: 28895560

Variant Present in the following documents:

• Main text
• leu2017257a.pdf

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Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples.

Journal Of Translational Medicine

Dallol, Ashraf A; Buhmeida, Abdelbaset A; Al-Ahwal, Mahmoud Shaheen MS; Al-Maghrabi, Jaudah J; Bajouh, Osama O; Al-Khayyat, Shadi S; Alam, Rania R; Abusanad, Atlal A; Turki, Rola R; Elaimi, Aisha A; Alhadrami, Hani A HA; Abuzenadah, Mohammed M; Banni, Huda H; Al-Qahtani, Mohammed H MH; Abuzenadah, Adel M AM

Publication Date: 2016-05-04

Variant appearance in text: FLT3: Lys602Arg

PubMed Link: 27146902

Variant Present in the following documents:

• Main text
• 12967_2016_Article_878.pdf

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