BRCA2 c.5953_5955del ;(p.S1985del)

Variant ID: 13-32914445-ATCT-A

NM_000059.3(BRCA2):c.5953_5955del;(p.S1985del)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Landscape of homologous recombination deficiencies in solid tumours: analyses of two independent genomic datasets.

Bmc Cancer
Lai, Zhongwu Z; Brosnan, Matthew M; Sokol, Ethan S ES; Xie, Mingchao M; Dry, Jonathan R JR; Harrington, Elizabeth A EA; Barrett, J Carl JC; Hodgson, Darren D
Publication Date: 2022-01-03

Variant appearance in text: BRCA2: S1985del
PubMed Link: 34979999
Variant Present in the following documents:
  • 12885_2021_9082_MOESM1_ESM.pdf
View BVdb publication page



PARP inhibitor resistance: the underlying mechanisms and clinical implications.

Molecular Cancer
Li, He H; Liu, Zhao-Yi ZY; Wu, Nayiyuan N; Chen, Yong-Chang YC; Cheng, Quan Q; Wang, Jing J
Publication Date: 2020-06-20

Variant appearance in text: BRCA2: S1985del
PubMed Link: 32563252
Variant Present in the following documents:
  • Main text
  • 12943_2020_Article_1227.pdf
View BVdb publication page



Polyclonal BRCA2 mutations following carboplatin treatment confer resistance to the PARP inhibitor rucaparib in a patient with mCRPC: a case report.

Bmc Cancer
Simmons, Andrew D AD; Nguyen, Minh M; Pintus, Elias E
Publication Date: 2020-03-14

Variant appearance in text: BRCA2: S1985del
PubMed Link: 32171277
Variant Present in the following documents:
  • Main text
  • 12885_2020_Article_6657.pdf
View BVdb publication page