A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene.
Plos Genetics
Wong, Cavin C; Chen, Fei F; Alirezaie, Najmeh N; Wang, Yifan Y; Cuggia, Adeline A; Borgida, Ayelet A; Holter, Spring S; Lenko, Tatiana T; Domecq, Celine C; , ; Petersen, Gloria M GM; Syngal, Sapna S; Brand, Randall R; Rustgi, Anil K AK; Cote, Michele L ML; Stoffel, Elena E; Olson, Sara H SH; Roberts, Nicholas J NJ; Akbari, Mohammad R MR; Majewski, Jacek J; Klein, Alison P AP; Greenwood, Celia M T CMT; Gallinger, Steven S; Zogopoulos, George G
Publication Date: 2019-08
Variant appearance in text: BRCA2: 8279G>T; G2760V
Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models.
Genetics In Medicine : Official Journal Of The American College Of Medical Genetics
Hart, Steven N SN; Hoskin, Tanya T; Shimelis, Hermela H; Moore, Raymond M RM; Feng, Bingjian B; Thomas, Abigail A; Lindor, Noralane M NM; Polley, Eric C EC; Goldgar, David E DE; Iversen, Edwin E; Monteiro, Alvaro N A ANA; Suman, Vera J VJ; Couch, Fergus J FJ