Publications:

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Addition of Gallic Acid Overcomes Resistance to Cisplatin in Ovarian Cancer Cell Lines.

Asian Pacific Journal Of Cancer Prevention : Apjcp

Al Balushi, Najwa N; Hassan, Syed Imran SI; Abdullah, Nada N; Al Dhahli, Buthaina B; Al Bahlani, Shadia S; Ahmed, Ikhlas I; Tsang, Benjamin K BK; Dobretsov, Sergey S; Tamimi, Yahya Y; Burney, Ikram A IA

Publication Date: 2022-08-01

Variant appearance in text: BRCA2: A2780S

PubMed Link: 36037120

Variant Present in the following documents:

• Main text
• APJCP-23-2661.pdf

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Combined inhibition of BADSer99 phosphorylation and PARP ablates models of recurrent ovarian carcinoma.

Communications Medicine

Zhang, Xi X; Wang, Liqiong L; Chen, Shu S; Huang, Peng P; Ma, Lan L; Ding, Hui H; Basappa, Basappa B; Zhu, Tao T; Lobie, Peter E PE; Pandey, Vijay V

Publication Date: 2022

Variant appearance in text: BRCA2: A2780S

PubMed Link: 35791346

Variant Present in the following documents:

• 43856_2022_142_MOESM1_ESM.pdf

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Understanding and predicting the functional consequences of missense mutations in BRCA1 and BRCA2.

Scientific Reports

Aljarf, Raghad R; Shen, Mengyuan M; Pires, Douglas E V DEV; Ascher, David B DB

Publication Date: 2022-06-21

Variant appearance in text: BRCA2: A2780S

PubMed Link: 35729312

Variant Present in the following documents:

• 41598_2022_13508_MOESM2_ESM.xlsx, sheet 1

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Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer.

Cell Reports. Medicine

Huang, Dongqing D; Chowdhury, Shrabanti S; Wang, Hong H; Savage, Sara R SR; Ivey, Richard G RG; Kennedy, Jacob J JJ; Whiteaker, Jeffrey R JR; Lin, Chenwei C; Hou, Xiaonan X; Oberg, Ann L AL; Larson, Melissa C MC; Eskandari, Najmeh N; Delisi, Davide A DA; Gentile, Saverio S; Huntoon, Catherine J CJ; Voytovich, Uliana J UJ; Shire, Zahra J ZJ; Yu, Qing Q; Gygi, Steven P SP; Hoofnagle, Andrew N AN; Herbert, Zachary T ZT; Lorentzen, Travis D TD; Calinawan, Anna A; Karnitz, Larry M LM; Weroha, S John SJ; Kaufmann, Scott H SH; Zhang, Bing B; Wang, Pei P; Birrer, Michael J MJ; Paulovich, Amanda G AG

Publication Date: 2021-12-21

Variant appearance in text: BRCA2: A2780s

PubMed Link: 35028612

Variant Present in the following documents:

• Main text
• main.pdf
• mmc6.pdf

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A highly annotated database of genes associated with platinum resistance in cancer.

Oncogene

Huang, Dongqing D; Savage, Sara R SR; Calinawan, Anna P AP; Lin, Chenwei C; Zhang, Bing B; Wang, Pei P; Starr, Timothy K TK; Birrer, Michael J MJ; Paulovich, Amanda G AG

Publication Date: 2021-11

Variant appearance in text: BRCA2: A2780s

PubMed Link: 34645978

Variant Present in the following documents:

• 41388_2021_2055_MOESM1_ESM.xlsx, sheet 1

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Malformin-A1 (MA1) Sensitizes Chemoresistant Ovarian Cancer Cells to Cisplatin-Induced Apoptosis.

Molecules (Basel, Switzerland)

Abdullah, Nada N; Tamimi, Yahya Y; Dobretsov, Sergey S; Balushi, Najwa Al NA; Alshekaili, Jalila J; Al Balushi, Hamed H; Al Kindi, Mahmood M; Hassan, Syed Imran SI; Bahlani, Shadia Al SA; Tsang, Benjamin K BK; Burney, Ikram A IA

Publication Date: 2021-06-13

Variant appearance in text: BRCA2: A2780S

PubMed Link: 34199287

Variant Present in the following documents:

• Main text
• molecules-26-03624.pdf

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Prediction of the functional impact of missense variants in BRCA1 and BRCA2 with BRCA-ML.

Npj Breast Cancer

Hart, Steven N SN; Polley, Eric C EC; Shimelis, Hermella H; Yadav, Siddhartha S; Couch, Fergus J FJ

Publication Date: 2020

Variant appearance in text: BRCA2: 8338G>T; Ala2780Ser

PubMed Link: 32377563

Variant Present in the following documents:

• 41523_2020_159_MOESM3_ESM.xlsx, sheet 1

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Interplay Between MicroRNAs and Oxidative Stress in Ovarian Conditions with a Focus on Ovarian Cancer and Endometriosis.

International Journal Of Molecular Sciences

Marí-Alexandre, Josep J; Carcelén, Antonio Pellín AP; Agababyan, Cristina C; Moreno-Manuel, Andrea A; García-Oms, Javier J; Calabuig-Fariñas, Silvia S; Gilabert-Estellés, Juan J

Publication Date: 2019-10-25

Variant appearance in text: BRCA2: A2780S

PubMed Link: 31731537

Variant Present in the following documents:

• Main text
• ijms-20-05322.pdf

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Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics

Hart, Steven N SN; Hoskin, Tanya T; Shimelis, Hermela H; Moore, Raymond M RM; Feng, Bingjian B; Thomas, Abigail A; Lindor, Noralane M NM; Polley, Eric C EC; Goldgar, David E DE; Iversen, Edwin E; Monteiro, Alvaro N A ANA; Suman, Vera J VJ; Couch, Fergus J FJ

Publication Date: 2019-01

Variant appearance in text: BRCA2: A2780S

PubMed Link: 29884841

Variant Present in the following documents:

• NIHMS953431-supplement-Table_S2.xls, sheet 1

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The RNA binding protein SORBS2 suppresses metastatic colonization of ovarian cancer by stabilizing tumor-suppressive immunomodulatory transcripts.

Genome Biology

Zhao, Linjie L; Wang, Wei W; Huang, Shuang S; Yang, Zhengnan Z; Xu, Lian L; Yang, Qilian Q; Zhou, Xiu X; Wang, Jinjin J; Shen, Qiuhong Q; Wang, Chenlu C; Le, Xiaobing X; Feng, Min M; Zhou, Nianxin N; Lau, Wayne Bond WB; Lau, Bonnie B; Yao, Shaohua S; Yi, Tao T; Wang, Xin X; Zhao, Xia X; Wei, Yuquan Y; Zhou, Shengtao S

Publication Date: 2018-03-16

Variant appearance in text: BRCA2: A2780s

PubMed Link: 29548303

Variant Present in the following documents:

• Main text
• 13059_2018_Article_1412.pdf

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The temporal dynamics of chromosome instability in ovarian cancer cell lines and primary patient samples.

Plos Genetics

Penner-Goeke, Signe S; Lichtensztejn, Zelda Z; Neufeld, Megan M; Ali, Jennifer L JL; Altman, Alon D AD; Nachtigal, Mark W MW; McManus, Kirk J KJ

Publication Date: 2017-04

Variant appearance in text: BRCA2: A2780s

PubMed Link: 28376088

Variant Present in the following documents:

• Main text
• pgen.1006707.pdf

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Ovarian epithelial cancer stem cells.

Thescientificworldjournal

Conic, Irena I; Dimov, Irena I; Tasic-Dimov, Desanka D; Djordjevic, Biljana B; Stefanovic, Vladisav V

Publication Date: 2011-06-09

Variant appearance in text: BRCA2: A2780s

PubMed Link: 21666993

Variant Present in the following documents:

• TSWJ-2011-11-847350.pdf

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LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer.

Cancer Research

Permuth-Wey, Jennifer J; Kim, Donghwa D; Tsai, Ya-Yu YY; Lin, Hui-Yi HY; Chen, Y Ann YA; Barnholtz-Sloan, Jill J; Birrer, Michael J MJ; Bloom, Gregory G; Chanock, Stephen J SJ; Chen, Zhihua Z; Cramer, Daniel W DW; Cunningham, Julie M JM; Dagne, Getachew G; Ebbert-Syfrett, Judith J; Fenstermacher, David D; Fridley, Brooke L BL; Garcia-Closas, Montserrat M; Gayther, Simon A SA; Ge, William W; Gentry-Maharaj, Aleksandra A; Gonzalez-Bosquet, Jesus J; Goode, Ellen L EL; Iversen, Edwin E; Jim, Heather H; Kong, William W; McLaughlin, John J; Menon, Usha U; Monteiro, Alvaro N A AN; Narod, Steven A SA; Pharoah, Paul D P PD; Phelan, Catherine M CM; Qu, Xiaotao X; Ramus, Susan J SJ; Risch, Harvey H; Schildkraut, Joellen M JM; Song, Honglin H; Stockwell, Heather H; Sutphen, Rebecca R; Terry, Kathryn L KL; Tyrer, Jonathan J; Vierkant, Robert A RA; Wentzensen, Nicolas N; Lancaster, Johnathan M JM; Cheng, Jin Q JQ; Sellers, Thomas A TA; ,

Publication Date: 2011-06-01

Variant appearance in text: BRCA2: A2780S

PubMed Link: 21482675

Variant Present in the following documents:

• Main text

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BRCA1 as a Therapeutic Target in Sporadic Epithelial Ovarian Cancer.

Journal Of Oncology

Clark-Knowles, Katherine V KV; O'Brien, Anna M AM; Weberpals, Johanne I JI

Publication Date: 2010

Variant appearance in text: BRCA2: A2780s

PubMed Link: 20182637

Variant Present in the following documents:

• Main text
• JO2010-891059.pdf

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