Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival.
Nature Communications
Anderson, Nathaniel D ND; Babichev, Yael Y; Fuligni, Fabio F; Comitani, Federico F; Layeghifard, Mehdi M; Venier, Rosemarie E RE; Dentro, Stefan C SC; Maheshwari, Anant A; Guram, Sheena S; Wunker, Claire C; Thompson, J Drew JD; Yuki, Kyoko E KE; Hou, Huayun H; Zatzman, Matthew M; Light, Nicholas N; Bernardini, Marcus Q MQ; Wunder, Jay S JS; Andrulis, Irene L IL; Ferguson, Peter P; Razak, Albiruni R Abdul ARA; Swallow, Carol J CJ; Dowling, James J JJ; Al-Awar, Rima S RS; Marcellus, Richard R; Rouzbahman, Marjan M; Gerstung, Moritz M; Durocher, Daniel D; Alexandrov, Ludmil B LB; Dickson, Brendan C BC; Gladdy, Rebecca A RA; Shlien, Adam A
Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.
Cancer Medicine
Sivapiragasam, Abirami A; Ashok Kumar, Prashanth P; Sokol, Ethan S ES; Albacker, Lee A LA; Killian, Jonathan K JK; Ramkissoon, Shakti H SH; Huang, Richard S P RSP; Severson, Eric A EA; Brown, Charlotte A CA; Danziger, Natalie N; McGregor, Kimberly K; Ross, Jeffrey S JS
Identification of relevant genetic alterations in cancer using topological data analysis.
Nature Communications
Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG
mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.
Cell Reports
Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM
Pan-urologic cancer genomic subtypes that transcend tissue of origin.
Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Meta-Analysis of the Luminal and Basal Subtypes of Bladder Cancer and the Identification of Signature Immunohistochemical Markers for Clinical Use.
Ebiomedicine
Dadhania, Vipulkumar V; Zhang, Miao M; Zhang, Li L; Bondaruk, Jolanta J; Majewski, Tadeusz T; Siefker-Radtke, Arlene A; Guo, Charles C CC; Dinney, Colin C; Cogdell, David E DE; Zhang, Shizhen S; Lee, Sangkyou S; Lee, June G JG; Weinstein, John N JN; Baggerly, Keith K; McConkey, David D; Czerniak, Bogdan B