ABCC4 c.1460G>A ;(p.G487E)

Variant ID: 13-95839040-C-T

NM_005845.3(ABCC4):c.1460G>A;(p.G487E)

This variant was identified in 15 publications

View GRCh38 version.




Publications:


Influence of SULT1A1*2 Polymorphism on Plasma Efavirenz Concentration in Thai HIV-1 Patients.

Pharmacogenomics And Personalized Medicine
Chamnanphon, Monpat M; Sukprasong, Rattanaporn R; Gaedigk, Andrea A; Manosuthi, Weerawat W; Chariyavilaskul, Pajaree P; Wittayalertpanya, Supeecha S; Koomdee, Napatrupron N; Jantararoungtong, Thawinee T; Puangpetch, Apichaya A; Sukasem, Chonlaphat C
Publication Date: 2021

Variant appearance in text: rs11568668
PubMed Link: 34335044
Variant Present in the following documents:
  • Main text
  • pgpm-14-915.pdf
View BVdb publication page



Study of Endogen Substrates, Drug Substrates and Inhibitors Binding Conformations on MRP4 and Its Variants by Molecular Docking and Molecular Dynamics.

Molecules (Basel, Switzerland)
Becerra, Edgardo E; Aguilera-Durán, Giovanny G; Berumen, Laura L; Romo-Mancillas, Antonio A; García-Alcocer, Guadalupe G
Publication Date: 2021-02-17

Variant appearance in text: MRP4: G487E
PubMed Link: 33671368
Variant Present in the following documents:
  • Main text
  • molecules-26-01051.pdf
View BVdb publication page



A Human ABC Transporter ABCC4 Gene SNP (rs11568658, 559 G > T, G187W) Reduces ABCC4-Dependent Drug Resistance.

Cells
Tsukamoto, Megumi M; Yamashita, Miho M; Nishi, Tsuyoshi T; Nakagawa, Hiroshi H
Publication Date: 2019-01-10

Variant appearance in text: ABCC4: G487E; rs11568668
PubMed Link: 30634695
Variant Present in the following documents:
  • Main text
  • cells-08-00039.pdf
View BVdb publication page



Individual susceptibility to arsenic-induced diseases: the role of host genetics, nutritional status, and the gut microbiome.

Mammalian Genome : Official Journal Of The International Mammalian Genome Society
Chi, Liang L; Gao, Bei B; Tu, Pengcheng P; Liu, Chih-Wei CW; Xue, Jingchuan J; Lai, Yunjia Y; Ru, Hongyu H; Lu, Kun K
Publication Date: 2018-02

Variant appearance in text: MRP4: G487E
PubMed Link: 29429126
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic variation in human drug-related genes.

Genome Medicine
Schärfe, Charlotta Pauline Irmgard CPI; Tremmel, Roman R; Schwab, Matthias M; Kohlbacher, Oliver O; Marks, Debora Susan DS
Publication Date: 2017-12-22

Variant appearance in text: rs11568668
PubMed Link: 29273096
Variant Present in the following documents:
  • 13073_2017_502_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Quantitative Evaluation of Drug Resistance Profile of Cells Expressing Wild-Type or Genetic Polymorphic Variants of the Human ABC Transporter ABCC4.

International Journal Of Molecular Sciences
Tsukamoto, Megumi M; Sato, Shiori S; Satake, Kazuhiro K; Miyake, Mizuki M; Nakagawa, Hiroshi H
Publication Date: 2017-07-04

Variant appearance in text: rs11568668
PubMed Link: 28677646
Variant Present in the following documents:
  • Main text
  • ijms-18-01435.pdf
View BVdb publication page



Population-Specific Resequencing Associates the ATP-Binding Cassette Subfamily C Member 4 Gene With Gout in New Zealand Māori and Pacific Men.

Arthritis & Rheumatology (Hoboken, N.J.)
Tanner, Callum C; Boocock, James J; Stahl, Eli A EA; Dobbyn, Amanda A; Mandal, Asim K AK; Cadzow, Murray M; Phipps-Green, Amanda J AJ; Topless, Ruth K RK; Hindmarsh, Jennie Harré JH; Stamp, Lisa K LK; Dalbeth, Nicola N; Choi, Hyon K HK; Mount, David B DB; Merriman, Tony R TR
Publication Date: 2017-07

Variant appearance in text: ABCC4: G487E
PubMed Link: 28371506
Variant Present in the following documents:
  • Main text
View BVdb publication page



Characterization of ADME gene variation in 21 populations by exome sequencing.

Pharmacogenetics And Genomics
Hovelson, Daniel H DH; Xue, Zhengyu Z; Zawistowski, Matthew M; Ehm, Margaret G MG; Harris, Elizabeth C EC; Stocker, Sophie L SL; Gross, Annette S AS; Jang, In-Jin IJ; Ieiri, Ichiro I; Lee, Jong-Eun JE; Cardon, Lon R LR; Chissoe, Stephanie L SL; Abecasis, Gonçalo G; Nelson, Matthew R MR
Publication Date: 2017-03

Variant appearance in text: ABCC4: Gly487Glu; rs11568668
PubMed Link: 27984508
Variant Present in the following documents:
  • fpc-27-089-s005.xlsx, sheet 2
View BVdb publication page



Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One
Holehouse, Alex S AS; Naegle, Kristen M KM
Publication Date: 2015

Variant appearance in text: rs11568668
PubMed Link: 26659599
Variant Present in the following documents:
  • pone.0144692.s002.xlsx, sheet 1
View BVdb publication page



Multidrug resistance-associated protein 4 is a determinant of arsenite resistance.

Oncology Reports
Yuan, Bo B; Yoshino, Yuta Y; Fukushima, Hisayo H; Markova, Svetlana S; Takagi, Norio N; Toyoda, Hiroo H; Kroetz, Deanna L DL
Publication Date: 2016-01

Variant appearance in text: MRP4: G487E
PubMed Link: 26497925
Variant Present in the following documents:
  • Main text
  • or-35-01-0147.pdf
View BVdb publication page



GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics
Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J
Publication Date: 2015-07-25

Variant appearance in text: ABCC4: G487E
PubMed Link: 26206375
Variant Present in the following documents:
  • 12859_2015_673_MOESM1_ESM.xls, sheet 4
View BVdb publication page



Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains.

Protein Science : A Publication Of The Protein Society
Kelly, Libusha L; Fukushima, Hisayo H; Karchin, Rachel R; Gow, Jason M JM; Chinn, Leslie W LW; Pieper, Ursula U; Segal, Mark R MR; Kroetz, Deanna L DL; Sali, Andrej A
Publication Date: 2010-11

Variant appearance in text: ABCC4: G487E
PubMed Link: 20799350
Variant Present in the following documents:
  • Main text
View BVdb publication page



Xenobiotic, bile acid, and cholesterol transporters: function and regulation.

Pharmacological Reviews
Klaassen, Curtis D CD; Aleksunes, Lauren M LM
Publication Date: 2010-03

Variant appearance in text: ABCC4: G487E
PubMed Link: 20103563
Variant Present in the following documents:
  • Main text
View BVdb publication page



The pharmacogenomics of membrane transporters project: research at the interface of genomics and transporter pharmacology.

Clinical Pharmacology And Therapeutics
Kroetz, D L DL; Yee, S W SW; Giacomini, K M KM
Publication Date: 2010-01

Variant appearance in text: ABCC4: G487E; rs11568668
PubMed Link: 19940846
Variant Present in the following documents:
  • Main text
View BVdb publication page



The human multidrug resistance protein 4 (MRP4, ABCC4): functional analysis of a highly polymorphic gene.

The Journal Of Pharmacology And Experimental Therapeutics
Abla, Nada N; Chinn, Leslie W LW; Nakamura, Tsutomu T; Liu, Li L; Huang, Conrad C CC; Johns, Susan J SJ; Kawamoto, Michiko M; Stryke, Doug D; Taylor, Travis R TR; Ferrin, Thomas E TE; Giacomini, Kathleen M KM; Kroetz, Deanna L DL
Publication Date: 2008-06

Variant appearance in text: MRP4: G487E; rs11568668
PubMed Link: 18364470
Variant Present in the following documents:
  • Main text
View BVdb publication page