Publications:

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Cardiac calcium regulation in human induced pluripotent stem cell cardiomyocytes: Implications for disease modeling and maturation.

Frontiers In Cell And Developmental Biology

Ernst, Patrick P; Bidwell, Philip A PA; Dora, Michaela M; Thomas, David D DD; Kamdar, Forum F

Publication Date: 2022

Variant appearance in text: MYH7: Arg442Gly

PubMed Link: 36742199

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• Main text
• fcell-10-986107.pdf

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Ventricular arrhythmia and sudden cardiac death in hypertrophic cardiomyopathy: From bench to bedside.

Frontiers In Cardiovascular Medicine

Shen, Hua H; Dong, Shi-Yong SY; Ren, Ming-Shi MS; Wang, Rong R

Publication Date: 2022

Variant appearance in text: MYH7: R442G

PubMed Link: 36061538

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• Main text
• fcvm-09-949294.pdf

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Modeling hypertrophic cardiomyopathy with human cardiomyocytes derived from induced pluripotent stem cells.

Stem Cell Research & Therapy

Li, Jiangtao J; Feng, Xin X; Wei, Xiang X

Publication Date: 2022-06-03

Variant appearance in text: MYH7: Arg442Gly

PubMed Link: 35659761

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• Main text
• 13287_2022_Article_2905.pdf

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Cell cycle defects underlie childhood-onset cardiomyopathy associated with Noonan syndrome.

Iscience

Meier, Anna B AB; Raj Murthi, Sarala S; Rawat, Hilansi H; Toepfer, Christopher N CN; Santamaria, Gianluca G; Schmid, Manuel M; Mastantuono, Elisa E; Schwarzmayr, Thomas T; Berutti, Riccardo R; Cleuziou, Julie J; Ewert, Peter P; Görlach, Agnes A; Klingel, Karin K; Laugwitz, Karl-Ludwig KL; Seidman, Christine E CE; Seidman, Jonathan G JG; Moretti, Alessandra A; Wolf, Cordula M CM

Publication Date: 2022-01-21

Variant appearance in text: MYH7: R442G

PubMed Link: 34988410

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Ion Channel Impairment and Myofilament Ca2+ Sensitization: Two Parallel Mechanisms Underlying Arrhythmogenesis in Hypertrophic Cardiomyopathy.

Cells

Santini, Lorenzo L; Coppini, Raffaele R; Cerbai, Elisabetta E

Publication Date: 2021-10-18

Variant appearance in text: MYH7: R442G

PubMed Link: 34685769

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• Main text
• cells-10-02789.pdf

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Human iPSCs and Genome Editing Technologies for Precision Cardiovascular Tissue Engineering.

Frontiers In Cell And Developmental Biology

Gähwiler, Eric K N EKN; Motta, Sarah E SE; Martin, Marcy M; Nugraha, Bramasta B; Hoerstrup, Simon P SP; Emmert, Maximilian Y MY

Publication Date: 2021

Variant appearance in text: MYH7: R442G

PubMed Link: 34262897

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• Main text
• fcell-09-639699.pdf

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Uncovering Inherited Cardiomyopathy With Human Induced Pluripotent Stem Cells.

Frontiers In Cell And Developmental Biology

Jiang, Xue X; Chen, Yihuan Y; Liu, Xiaofeng X; Ye, Lingqun L; Yu, Miao M; Shen, Zhenya Z; Lei, Wei W; Hu, Shijun S

Publication Date: 2021

Variant appearance in text: MYH7: R442G

PubMed Link: 34079803

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• Main text
• fcell-09-672039.pdf

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Genetic Cardiomyopathies: The Lesson Learned from hiPSCs.

Journal Of Clinical Medicine

My, Ilaria I; Di Pasquale, Elisa E

Publication Date: 2021-03-09

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PubMed Link: 33803477

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• jcm-10-01149.pdf

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Drug Development and the Use of Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Disease Modeling and Drug Toxicity Screening.

International Journal Of Molecular Sciences

Ovics, Paz P; Regev, Danielle D; Baskin, Polina P; Davidor, Mor M; Shemer, Yuval Y; Neeman, Shunit S; Ben-Haim, Yael Y; Binah, Ofer O

Publication Date: 2020-10-03

Variant appearance in text: MYH7: R442G

PubMed Link: 33023024

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• Main text
• ijms-21-07320.pdf

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Preventative therapeutic approaches for hypertrophic cardiomyopathy.

The Journal Of Physiology

Solomon, Tanya T; Filipovska, Aleksandra A; Hool, Livia L; Viola, Helena H

Publication Date: 2021-07

Variant appearance in text: MYH7: Arg442Gly

PubMed Link: 32822065

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INDUCED PLURIPOTENT STEM CELLS FOR MODELLING ENERGETIC ALTERATIONS IN HYPERTROPHIC CARDIOMYOPATHY.

Conditioning Medicine

Ramachandra, Chrishan J A CJA; Mai Ja, K P Myu KPM; Lin, Ying-Hsi YH; Shim, Winston W; Boisvert, William A WA; Hausenloy, Derek J DJ

Publication Date: 2019

Variant appearance in text: MYH7: Arg442Gly

PubMed Link: 32457935

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Human Induced Pluripotent Stem-Cell-Derived Cardiomyocytes as Models for Genetic Cardiomyopathies.

International Journal Of Molecular Sciences

Brodehl, Andreas A; Ebbinghaus, Hans H; Deutsch, Marcus-André MA; Gummert, Jan J; Gärtner, Anna A; Ratnavadivel, Sandra S; Milting, Hendrik H

Publication Date: 2019-09-06

Variant appearance in text: MYH7: R442G

PubMed Link: 31489928

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• Main text
• ijms-20-04381.pdf

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Modelling sarcomeric cardiomyopathies with human cardiomyocytes derived from induced pluripotent stem cells.

The Journal Of Physiology

Sewanan, Lorenzo R LR; Campbell, Stuart G SG

Publication Date: 2020-07

Variant appearance in text: MYH7: Arg442Gly

PubMed Link: 30624779

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Cardiomyopathy phenotypes in human-induced pluripotent stem cell-derived cardiomyocytes-a systematic review.

Pflugers Archiv : European Journal Of Physiology

Eschenhagen, Thomas T; Carrier, Lucie L

Publication Date: 2019-05

Variant appearance in text: MYH7: Arg442Gly

PubMed Link: 30324321

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Concise Review: The Current State of Human In Vitro Cardiac Disease Modeling: A Focus on Gene Editing and Tissue Engineering.

Stem Cells Translational Medicine

Hoes, Martijn F MF; Bomer, Nils N; van der Meer, Peter P

Publication Date: 2019-01

Variant appearance in text: MYH7: R442G

PubMed Link: 30302938

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• Main text
• SCT3-8-66.pdf

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Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation.

Stem Cell Reports

Li, Shishi S; Pan, Huaye H; Tan, Chao C; Sun, Yaping Y; Song, Yanrui Y; Zhang, Xuan X; Yang, Wei W; Wang, Xuexiang X; Li, Dan D; Dai, Yu Y; Ma, Qiang Q; Xu, Chenming C; Zhu, Xufen X; Kang, Lijun L; Fu, Yong Y; Xu, Xuejun X; Shu, Jing J; Zhou, Naiming N; Han, Feng F; Qin, Dajiang D; Huang, Wendong W; Liu, Zhong Z; Yan, Qingfeng Q

Publication Date: 2018-03-13

Variant appearance in text: MYH7: Arg442Gly

PubMed Link: 29456182

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• Main text
• main.pdf
• mmc4.pdf

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Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies.

Disease Models & Mechanisms

Brandão, Karina O KO; Tabel, Viola A VA; Atsma, Douwe E DE; Mummery, Christine L CL; Davis, Richard P RP

Publication Date: 2017-09-01

Variant appearance in text: MYH7: R442G

PubMed Link: 28883014

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Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes.

Cellular And Molecular Life Sciences : Cmls

Giacomelli, E E; Mummery, C L CL; Bellin, M M

Publication Date: 2017-10

Variant appearance in text: MYH7: R442G

PubMed Link: 28573431

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• Main text
• 18_2017_Article_2546.pdf

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Recent Advances in the Molecular Genetics of Familial Hypertrophic Cardiomyopathy in South Asian Descendants.

Frontiers In Physiology

Kraker, Jessica J; Viswanathan, Shiv Kumar SK; Knöll, Ralph R; Sadayappan, Sakthivel S

Publication Date: 2016

Variant appearance in text: MYH7: R442G

PubMed Link: 27840609

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Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine.

Physiological Reviews

Matsa, Elena E; Ahrens, John H JH; Wu, Joseph C JC

Publication Date: 2016-07

Variant appearance in text: MYH7: R442G

PubMed Link: 27335446

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Mutation-Specific Phenotypes in hiPSC-Derived Cardiomyocytes Carrying Either Myosin-Binding Protein C Or α-Tropomyosin Mutation for Hypertrophic Cardiomyopathy.

Stem Cells International

Ojala, Marisa M; Prajapati, Chandra C; Pölönen, Risto-Pekka RP; Rajala, Kristiina K; Pekkanen-Mattila, Mari M; Rasku, Jyrki J; Larsson, Kim K; Aalto-Setälä, Katriina K

Publication Date: 2016

Variant appearance in text: MYH7: R442G

PubMed Link: 27057166

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• Main text
• SCI2016-1684792.pdf

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Induced pluripotent stem cells: at the heart of cardiovascular precision medicine.

Nature Reviews. Cardiology

Chen, Ian Y IY; Matsa, Elena E; Wu, Joseph C JC

Publication Date: 2016-06

Variant appearance in text: MYH7: R442G

PubMed Link: 27009425

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Cardiovascular Disease Modeling Using Patient-Specific Induced Pluripotent Stem Cells.

International Journal Of Molecular Sciences

Tanaka, Atsushi A; Yuasa, Shinsuke S; Node, Koichi K; Fukuda, Keiichi K

Publication Date: 2015-08-12

Variant appearance in text: MYH7: R442G

PubMed Link: 26274955

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• ijms-16-18894-s001.xlsx, sheet 1

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Modelling sarcomeric cardiomyopathies in the dish: from human heart samples to iPSC cardiomyocytes.

Cardiovascular Research

Eschenhagen, Thomas T; Mummery, Christine C; Knollmann, Bjorn C BC

Publication Date: 2015-04-01

Variant appearance in text: MYH7: R442G

PubMed Link: 25618410

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• Main text
• cvv017.pdf

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Study familial hypertrophic cardiomyopathy using patient-specific induced pluripotent stem cells.

Cardiovascular Research

Han, Lu L; Li, Yang Y; Tchao, Jason J; Kaplan, Aaron D AD; Lin, Bo B; Li, You Y; Mich-Basso, Jocelyn J; Lis, Agnieszka A; Hassan, Narmeen N; London, Barry B; Bett, Glenna C L GC; Tobita, Kimimasa K; Rasmusson, Randall L RL; Yang, Lei L

Publication Date: 2014-11-01

Variant appearance in text: MYH7: Arg442Gly

PubMed Link: 25209314

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• Main text
• cvu205.pdf

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