Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: support for a sequential model of γ-secretase intramembrane proteolysis and regulation by the amyloid β precursor protein (APP) juxtamembrane region.
The Journal Of Biological Chemistry
Kukar, Thomas L TL; Ladd, Thomas B TB; Robertson, Paul P; Pintchovski, Sean A SA; Moore, Brenda B; Bann, Maralyssa A MA; Ren, Zhao Z; Jansen-West, Karen K; Malphrus, Kim K; Eggert, Simone S; Maruyama, Hiroko H; Cottrell, Barbara A BA; Das, Pritam P; Basi, Guriqbal S GS; Koo, Edward H EH; Golde, Todd E TE