Caspase-1 and Cathepsin B Inhibitors from Marine Invertebrates, Aiming at a Reduction in Neuroinflammation.
Marine Drugs
Moreno, Rafaela Indalecio RI; Zambelli, Vanessa O VO; Picolo, Gisele G; Cury, Yara Y; Morandini, André C AC; Marques, Antonio Carlos AC; Sciani, Juliana Mozer JM
Role of NLRP3 Inflammasome and Its Inhibitors as Emerging Therapeutic Drug Candidate for Alzheimer's Disease: a Review of Mechanism of Activation, Regulation, and Inhibition.
Inflammation
Sharma, Barkha B; Satija, Garvit G; Madan, Anish A; Garg, Mansi M; Alam, M Mumtaz MM; Shaquiquzzaman, M M; Khanna, Suruchi S; Tiwari, Prachi P; Parvez, Suhel S; Iqubal, Ashif A; Haque, Syed Ehtaishamul SE; Khan, Mohammad Ahmed MA
Ovocystatin Induced Changes in Expression of Alzheimer's Disease Relevant Proteins in APP/PS1 Transgenic Mice.
Journal Of Clinical Medicine
Stanczykiewicz, Bartlomiej B; Gburek, Jakub J; Rutkowska, Maria M; Lemieszewska, Marta M; Gołąb, Krzysztof K; Juszczyńska, Katarzyna K; Piotrowska, Aleksandra A; Trziszka, Tadeusz T; Dzięgiel, Piotr P; Podhorska-Okołów, Marzenna M; Zabłocka, Agnieszka A; Rymaszewska, Joanna J
Neuroprotective effects of p62(SQSTM1)-engineered lactic acid bacteria in Alzheimer's disease: a pre-clinical study.
Aging
Cecarini, Valentina V; Bonfili, Laura L; Gogoi, Olee O; Lawrence, Solomon S; Venanzi, Franco M FM; Azevedo, Vasco V; Mancha-Agresti, Pamela P; Drumond, Mariana Martins MM; Rossi, Giacomo G; Berardi, Sara S; Galosi, Livio L; Cuccioloni, Massimiliano M; Angeletti, Mauro M; Suchodolski, Jan S JS; Pilla, Rachel R; Lidbury, Jonathan A JA; Eleuteri, Anna Maria AM
The Role of Lysosomes in a Broad Disease-Modifying Approach Evaluated across Transgenic Mouse Models of Alzheimer's Disease and Parkinson's Disease and Models of Mild Cognitive Impairment.
International Journal Of Molecular Sciences
Hwang, Jeannie J; Estick, Candice M CM; Ikonne, Uzoma S US; Butler, David D; Pait, Morgan C MC; Elliott, Lyndsie H LH; Ruiz, Sarah S; Smith, Kaitlan K; Rentschler, Katherine M KM; Mundell, Cary C; Almeida, Michael F MF; Stumbling Bear, Nicole N; Locklear, James P JP; Abumohsen, Yara Y; Ivey, Cecily M CM; Farizatto, Karen L G KLG; Bahr, Ben A BA
c-Abl and Arg induce cathepsin-mediated lysosomal degradation of the NM23-H1 metastasis suppressor in invasive cancer.
Oncogene
Fiore, Leann S LS; Ganguly, Sourik S SS; Sledziona, James J; Cibull, Michael L ML; Wang, Chi C; Richards, Dana L DL; Neltner, Janna M JM; Beach, Carol C; McCorkle, Joseph R JR; Kaetzel, David M DM; Plattner, Rina R