Publications:

Activation of γ-Secretase Trimming Activity by Topological Changes of Transmembrane Domain 1 of Presenilin 1.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience

Cai, Tetsuo T; Yonaga, Masahiro M; Tomita, Taisuke T

Publication Date: 2017-12-13

Variant appearance in text: PS1: I100C

PubMed Link: 29118109

Variant Present in the following documents:

• Main text

View BVdb publication page

Cooperative roles of hydrophilic loop 1 and the C-terminus of presenilin 1 in the substrate-gating mechanism of γ-secretase.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience

Takagi-Niidome, Shizuka S; Sasaki, Tomoki T; Osawa, Satoko S; Sato, Takeshi T; Morishima, Kanan K; Cai, Tetsuo T; Iwatsubo, Takeshi T; Tomita, Taisuke T

Publication Date: 2015-02-11

Variant appearance in text: PS1: I100C

PubMed Link: 25673856

Variant Present in the following documents:

• Main text

View BVdb publication page

Participation of transmembrane domain 1 of presenilin 1 in the catalytic pore structure of the γ-secretase.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience

Takagi, Shizuka S; Tominaga, Aya A; Sato, Chihiro C; Tomita, Taisuke T; Iwatsubo, Takeshi T

Publication Date: 2010-11-24

Variant appearance in text: PS1: I100C

PubMed Link: 21106832

Variant Present in the following documents:

• Main text

View BVdb publication page