Publications:

---

Side-by-side comparison of Notch- and C83 binding to γ-secretase in a complete membrane model at physiological temperature.

Rsc Advances

Dehury, Budheswar B; Tang, Ning N; Mehra, Rukmankesh R; Blundell, Tom L TL; Kepp, Kasper P KP

Publication Date: 2020-08-21

Variant appearance in text: PS1: Q112C

PubMed Link: 35520661

Variant Present in the following documents:

• Main text
• RA-010-D0RA04683C.pdf

View BVdb publication page

---

Structural Studies Providing Insights into Production and Conformational Behavior of Amyloid-β Peptide Associated with Alzheimer's Disease Development.

Molecules (Basel, Switzerland)

Urban, Anatoly S AS; Pavlov, Konstantin V KV; Kamynina, Anna V AV; Okhrimenko, Ivan S IS; Arseniev, Alexander S AS; Bocharov, Eduard V EV

Publication Date: 2021-05-13

Variant appearance in text: PSEN1: Q112C

PubMed Link: 34068293

Variant Present in the following documents:

• Main text
• molecules-26-02897.pdf

View BVdb publication page

---

Hydrophilic loop 1 of Presenilin-1 and the APP GxxxG transmembrane motif regulate γ-secretase function in generating Alzheimer-causing Aβ peptides.

The Journal Of Biological Chemistry

Liu, Lei L; Lauro, Bianca M BM; Wolfe, Michael S MS; Selkoe, Dennis J DJ

Publication Date: 2021

Variant appearance in text: PS1: Q112C

PubMed Link: 33571524

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

---

Mechanisms of γ-Secretase Activation and Substrate Processing.

Acs Central Science

Bhattarai, Apurba A; Devkota, Sujan S; Bhattarai, Sanjay S; Wolfe, Michael S MS; Miao, Yinglong Y

Publication Date: 2020-06-24

Variant appearance in text: PS1: Q112C

PubMed Link: 32607444

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Substrate-Enzyme Interactions in Intramembrane Proteolysis: γ-Secretase as the Prototype.

Frontiers In Molecular Neuroscience

Liu, Xinyue X; Zhao, Jing J; Zhang, Yingkai Y; Ubarretxena-Belandia, Iban I; Forth, Scott S; Lieberman, Raquel L RL; Wang, Chunyu C

Publication Date: 2020

Variant appearance in text: PS1: Q112C

PubMed Link: 32508589

Variant Present in the following documents:

• Main text
• fnmol-13-00065.pdf

View BVdb publication page

---

Extracellular interface between APP and Nicastrin regulates Aβ length and response to γ-secretase modulators.

The Embo Journal

Petit, Dieter D; Hitzenberger, Manuel M; Lismont, Sam S; Zoltowska, Katarzyna Marta KM; Ryan, Natalie S NS; Mercken, Marc M; Bischoff, François F; Zacharias, Martin M; Chávez-Gutiérrez, Lucía L

Publication Date: 2019-06-17

Variant appearance in text: PSEN1: Q112C

PubMed Link: 31109937

Variant Present in the following documents:

• Main text
• EMBJ-38-e101494.pdf

View BVdb publication page

---