Publications:

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Targeting Glucose Metabolism of Cancer Cells with Dichloroacetate to Radiosensitize High-Grade Gliomas.

International Journal Of Molecular Sciences

Cook, Kristina M KM; Shen, Han H; McKelvey, Kelly J KJ; Gee, Harriet E HE; Hau, Eric E

Publication Date: 2021-07-06

Variant appearance in text: rs7160195

PubMed Link: 34298883

Variant Present in the following documents:

• Main text
• ijms-22-07265.pdf

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Ethnicity-Dependent Effects of Schizophrenia Risk Variants of the OLIG2 Gene on OLIG2 Transcription and White Matter Integrity.

Schizophrenia Bulletin

Komatsu, Hiroshi H; Takeuchi, Hikaru H; Kikuchi, Yoshie Y; Ono, Chiaki C; Yu, Zhiqian Z; Iizuka, Kunio K; Takano, Yuji Y; Kakuto, Yoshihisa Y; Funakoshi, Shunichi S; Ono, Takashi T; Ito, Junko J; Kunii, Yasuto Y; Hino, Mizuki M; Nagaoka, Atsuko A; Iwasaki, Yasushi Y; Yamamori, Hidenaga H; Yasuda, Yuka Y; Fujimoto, Michiko M; Azechi, Hirotsugu H; Kudo, Noriko N; Hashimoto, Ryota R; Yabe, Hirooki H; Yoshida, Mari M; Saito, Yuko Y; Kakita, Akiyoshi A; Fuse, Nobuo N; Kawashima, Ryuta R; Taki, Yasuyuki Y; Tomita, Hiroaki H

Publication Date: 2020-12-01

Variant appearance in text: rs7160195

PubMed Link: 32285113

Variant Present in the following documents:

• Main text

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GSTZ1 genotypes correlate with dichloroacetate pharmacokinetics and chronic side effects in multiple myeloma patients in a pilot phase 2 clinical trial.

Pharmacology Research & Perspectives

Tian, Dan Dan DD; Bennett, Samuel K SK; Coupland, Lucy A LA; Forwood, Kathryn K; Lwin, Yadanar Y; Pooryousef, Niloofar N; Tea, Illa I; Truong, Thy T TT; Neeman, Teresa T; Crispin, Philip P; D'Rozario, James J; Blackburn, Anneke C AC

Publication Date: 2019-12

Variant appearance in text: rs7160195

PubMed Link: 31624634

Variant Present in the following documents:

• Main text
• PRP2-7-e00526.pdf

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Age-Related Changes in Expression and Activity of Human Hepatic Mitochondrial Glutathione Transferase Zeta1.

Drug Metabolism And Disposition: The Biological Fate Of Chemicals

Zhong, Guo G; James, Margaret O MO; Smeltz, Marci G MG; Jahn, Stephan C SC; Langaee, Taimour T; Simpson, Pippa P; Stacpoole, Peter W PW

Publication Date: 2018-08

Variant appearance in text: rs7160195

PubMed Link: 29853471

Variant Present in the following documents:

• Main text

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Therapeutic applications of dichloroacetate and the role of glutathione transferase zeta-1.

Pharmacology & Therapeutics

James, Margaret O MO; Jahn, Stephan C SC; Zhong, Guo G; Smeltz, Marci G MG; Hu, Zhiwei Z; Stacpoole, Peter W PW

Publication Date: 2017-02

Variant appearance in text: rs7160195

PubMed Link: 27771434

Variant Present in the following documents:

• Main text

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Pharmacogenetic considerations with dichloroacetate dosing.

Pharmacogenomics

James, Margaret O MO; Stacpoole, Peter W PW

Publication Date: 2016-05

Variant appearance in text: rs7160195

PubMed Link: 27143230

Variant Present in the following documents:

• Main text

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The influence of human GSTZ1 gene haplotype variations on GSTZ1 expression.

Pharmacogenetics And Genomics

Langaee, Taimour Y TY; Zhong, Guo G; Li, Wenjun W; Hamadeh, Issam I; Solayman, Mohamed Hassan M MH; McDonough, Caitrin W CW; Stacpoole, Peter W PW; James, Margaret O MO

Publication Date: 2015-05

Variant appearance in text: rs7160195

PubMed Link: 25738370

Variant Present in the following documents:

• Main text

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Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children.

Journal Of Clinical Pharmacology

Shroads, A L AL; Coats, B S BS; McDonough, C W CW; Langaee, T T; Stacpoole, P W PW

Publication Date: 2015-01

Variant appearance in text: rs7160195

PubMed Link: 25079374

Variant Present in the following documents:

• Main text

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Phase 1 trial of dichloroacetate (DCA) in adults with recurrent malignant brain tumors.

Investigational New Drugs

Dunbar, E M EM; Coats, B S BS; Shroads, A L AL; Langaee, T T; Lew, A A; Forder, J R JR; Shuster, J J JJ; Wagner, D A DA; Stacpoole, P W PW

Publication Date: 2014-06

Variant appearance in text: rs7160195

PubMed Link: 24297161

Variant Present in the following documents:

• Main text

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Long-term safety of dichloroacetate in congenital lactic acidosis.

Molecular Genetics And Metabolism

Abdelmalak, Monica M; Lew, Alicia A; Ramezani, Ryan R; Shroads, Albert L AL; Coats, Bonnie S BS; Langaee, Taimour T; Shankar, Meena N MN; Neiberger, Richard E RE; Subramony, S H SH; Stacpoole, Peter W PW

Publication Date: 2013-06

Variant appearance in text: rs7160195

PubMed Link: 23611579

Variant Present in the following documents:

• Main text

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