DICER1 c.5126A>C ;(p.D1709A)

Variant ID: 14-95560463-T-G

NM_177438.2(DICER1):c.5126A>C;(p.D1709A)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: DICER1: D1709A
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Morphologic, Immunohistochemical, and Genetic Differences Between High-grade and Low-grade Fetal Adenocarcinomas of the Lung.

The American Journal Of Surgical Pathology
Li, Yue Y; Xi, Shao-Yan SY; Yong, Juan-Juan JJ; Wu, Xiao-Yan XY; Yang, Xin-Hua XH; Wang, Fang F
Publication Date: 2021-11-01

Variant appearance in text: DICER1: D1709A
PubMed Link: 34138800
Variant Present in the following documents:
  • Main text
View BVdb publication page



RNA structure probing reveals the structural basis of Dicer binding and cleavage.

Nature Communications
Luo, Qing-Jun QJ; Zhang, Jinsong J; Li, Pan P; Wang, Qing Q; Zhang, Yue Y; Roy-Chaudhuri, Biswajoy B; Xu, Jianpeng J; Kay, Mark A MA; Zhang, Qiangfeng Cliff QC
Publication Date: 2021-06-07

Variant appearance in text: Dicer: D1709A
PubMed Link: 34099665
Variant Present in the following documents:
  • Main text
  • 41467_2021_Article_23607.pdf
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: DICER1: D1709A
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



Hotspot Mutations in DICER1 Causing GLOW Syndrome-Associated Macrocephaly via Modulation of Specific microRNA Populations Result in the Activation of PI3K/ATK/mTOR Signaling.

Microrna (Shariqah, United Arab Emirates)
Klein, Steven D SD; Martinez-Agosto, Julian A JA
Publication Date: 2020

Variant appearance in text: DICER1: D1709A
PubMed Link: 31232238
Variant Present in the following documents:
  • Main text
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: DICER1: D1709A
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



Induction and suppression of antiviral RNA interference by influenza A virus in mammalian cells.

Nature Microbiology
Li, Yang Y; Basavappa, Megha M; Lu, Jinfeng J; Dong, Shuwei S; Cronkite, D Alexander DA; Prior, John T JT; Reinecker, Hans-Christian HC; Hertzog, Paul P; Han, Yanhong Y; Li, Wan-Xiang WX; Cheloufi, Sihem S; Karginov, Fedor V FV; Ding, Shou-Wei SW; Jeffrey, Kate L KL
Publication Date: 2016-12-05

Variant appearance in text: Dicer: D1709A
PubMed Link: 27918527
Variant Present in the following documents:
  • Main text
View BVdb publication page



Ribozyme-enhanced single-stranded Ago2-processed interfering RNA triggers efficient gene silencing with fewer off-target effects.

Nature Communications
Shang, Renfu R; Zhang, Fengjuan F; Xu, Beiying B; Xi, Hairui H; Zhang, Xue X; Wang, Weihua W; Wu, Ligang L
Publication Date: 2015-10-12

Variant appearance in text: Dicer: D1709A
PubMed Link: 26455506
Variant Present in the following documents:
  • ncomms9430-s1.pdf
View BVdb publication page



Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B
Publication Date: 2014-10-28

Variant appearance in text: DICER1: D1709A
PubMed Link: 25348012
Variant Present in the following documents:
  • 13059_2014_484_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs.

Rna (New York, N.Y.)
Gurtan, Allan M AM; Lu, Victoria V; Bhutkar, Arjun A; Sharp, Phillip A PA
Publication Date: 2012-06

Variant appearance in text: Dicer: D1709A
PubMed Link: 22546613
Variant Present in the following documents:
  • Main text
View BVdb publication page