DICER1 c.3959A>C ;(p.D1320A)

Variant ID: 14-95569774-T-G

NM_177438.2(DICER1):c.3959A>C;(p.D1320A)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


An unexpected role for Dicer as a reader of the unacetylated DNA binding domain of p53 in transcriptional regulation.

Science Advances
Yang, Xin X; Wang, Xingwu X; Li, Zhiming Z; Duan, Shoufu S; Li, Huan H; Jin, Jian J; Zhang, Zhiguo Z; Gu, Wei W
Publication Date: 2021-10-29

Variant appearance in text: Dicer: D1320A
PubMed Link: 34705508
Variant Present in the following documents:
  • Main text
  • sciadv.abi6684.pdf
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RNA structure probing reveals the structural basis of Dicer binding and cleavage.

Nature Communications
Luo, Qing-Jun QJ; Zhang, Jinsong J; Li, Pan P; Wang, Qing Q; Zhang, Yue Y; Roy-Chaudhuri, Biswajoy B; Xu, Jianpeng J; Kay, Mark A MA; Zhang, Qiangfeng Cliff QC
Publication Date: 2021-06-07

Variant appearance in text: Dicer: D1320A
PubMed Link: 34099665
Variant Present in the following documents:
  • Main text
  • 41467_2021_Article_23607.pdf
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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: DICER1: D1320A
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



High-yield production of human Dicer by transfection of human HEK293-EBNA1 cells grown in suspension.

Bmc Biotechnology
Bouvette, Jonathan J; Korkut, Dursun Nizam DN; Fouillen, Aurélien A; Amellah, Soumiya S; Nanci, Antonio A; Durocher, Yves Y; Omichinski, James G JG; Legault, Pascale P
Publication Date: 2018-12-06

Variant appearance in text: Dicer: D1320A
PubMed Link: 30522464
Variant Present in the following documents:
  • Main text
  • 12896_2018_Article_485.pdf
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The RIG-I-like receptor LGP2 inhibits Dicer-dependent processing of long double-stranded RNA and blocks RNA interference in mammalian cells.

The Embo Journal
van der Veen, Annemarthe G AG; Maillard, Pierre V PV; Schmidt, Jan Marten JM; Lee, Sonia A SA; Deddouche-Grass, Safia S; Borg, Annabel A; Kjær, Svend S; Snijders, Ambrosius P AP; Reis e Sousa, Caetano C
Publication Date: 2018-02-15

Variant appearance in text: Dicer: D1320A
PubMed Link: 29351913
Variant Present in the following documents:
  • Main text
  • EMBJ-37-e97479-s001.pdf
  • EMBJ-37-e97479.pdf
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Induction and suppression of antiviral RNA interference by influenza A virus in mammalian cells.

Nature Microbiology
Li, Yang Y; Basavappa, Megha M; Lu, Jinfeng J; Dong, Shuwei S; Cronkite, D Alexander DA; Prior, John T JT; Reinecker, Hans-Christian HC; Hertzog, Paul P; Han, Yanhong Y; Li, Wan-Xiang WX; Cheloufi, Sihem S; Karginov, Fedor V FV; Ding, Shou-Wei SW; Jeffrey, Kate L KL
Publication Date: 2016-12-05

Variant appearance in text: Dicer: D1320A
PubMed Link: 27918527
Variant Present in the following documents:
  • Main text
View BVdb publication page



Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents.

Nucleic Acids Research
Zhang, Pei-Ying PY; Li, Guiling G; Deng, Zhu-Jun ZJ; Liu, Li-Yuan LY; Chen, Li L; Tang, Jun-Zhou JZ; Wang, Yu-Qun YQ; Cao, Su-Ting ST; Fang, Yu-Xiao YX; Wen, Fuping F; Xu, Yunsheng Y; Chen, Xiaoming X; Shi, Ke-Qing KQ; Li, Wen-Feng WF; Xie, Congying C; Tang, Kai-Fu KF
Publication Date: 2016-05-05

Variant appearance in text: Dicer: D1320A
PubMed Link: 26704979
Variant Present in the following documents:
  • Main text
  • supp_gkv1504_nar-01536-m-2015-File009.pdf
  • gkv1504.pdf
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Ribozyme-enhanced single-stranded Ago2-processed interfering RNA triggers efficient gene silencing with fewer off-target effects.

Nature Communications
Shang, Renfu R; Zhang, Fengjuan F; Xu, Beiying B; Xi, Hairui H; Zhang, Xue X; Wang, Weihua W; Wu, Ligang L
Publication Date: 2015-10-12

Variant appearance in text: Dicer: D1320A
PubMed Link: 26455506
Variant Present in the following documents:
  • Main text
  • ncomms9430.pdf
  • ncomms9430-s1.pdf
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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B
Publication Date: 2014-10-28

Variant appearance in text: DICER1: D1320A
PubMed Link: 25348012
Variant Present in the following documents:
  • 13059_2014_484_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs.

Rna (New York, N.Y.)
Gurtan, Allan M AM; Lu, Victoria V; Bhutkar, Arjun A; Sharp, Phillip A PA
Publication Date: 2012-06

Variant appearance in text: Dicer: D1320A
PubMed Link: 22546613
Variant Present in the following documents:
  • Main text
View BVdb publication page