DICER1 c.2582A>C ;(p.E861A)

Variant ID: 14-95574285-T-G

NM_177438.2(DICER1):c.2582A>C;(p.E861A)

This variant was identified in 14 publications

View GRCh38 version.




Publications:


ADAR1- and ADAR2-mediated regulation of maturation and targeting of miR-376b to modulate GABA neurotransmitter catabolism.

The Journal Of Biological Chemistry
Widmark, Albin A; Sagredo, Eduardo A EA; Karlström, Victor V; Behm, Mikaela M; Biryukova, Inna I; Friedländer, Marc R MR; Daniel, Chammiran C; Öhman, Marie M
Publication Date: 2022-03

Variant appearance in text: Dicer: E861A
PubMed Link: 35124003
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



RNA editing in mesothelioma: a look forward.

Open Biology
Hariharan, Ananya A; Sun, Suna S; Wipplinger, Martin M; Felley-Bosco, Emanuela E
Publication Date: 2020-10

Variant appearance in text: Dicer: E861A
PubMed Link: 33050791
Variant Present in the following documents:
  • Main text
  • rsob-10-200112.pdf
View BVdb publication page



ADAR-deficiency perturbs the global splicing landscape in mouse tissues.

Genome Research
Kapoor, Utkarsh U; Licht, Konstantin K; Amman, Fabian F; Jakobi, Tobias T; Martin, David D; Dieterich, Christoph C; Jantsch, Michael F MF
Publication Date: 2020-08

Variant appearance in text: Dicer: E861A
PubMed Link: 32727871
Variant Present in the following documents:
  • Main text
  • 1107.pdf
View BVdb publication page



Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila.

Nature Communications
Deng, Patricia P; Khan, Anzer A; Jacobson, Dionna D; Sambrani, Nagraj N; McGurk, Leeanne L; Li, Xianghua X; Jayasree, Aswathy A; Hejatko, Jan J; Shohat-Ophir, Galit G; O'Connell, Mary A MA; Li, Jin Billy JB; Keegan, Liam P LP
Publication Date: 2020-03-27

Variant appearance in text: Dicer: E861A
PubMed Link: 32221286
Variant Present in the following documents:
  • Main text
View BVdb publication page



An internal deletion of ADAR rescued by MAVS deficiency leads to a minute phenotype.

Nucleic Acids Research
Bajad, Prajakta P; Ebner, Florian F; Amman, Fabian F; Szabó, Brigitta B; Kapoor, Utkarsh U; Manjali, Greeshma G; Hildebrandt, Alwine A; Janisiw, Michael P MP; Jantsch, Michael F MF
Publication Date: 2020-04-06

Variant appearance in text: Dicer: E861A
PubMed Link: 31956894
Variant Present in the following documents:
  • gkaa025.pdf
View BVdb publication page



Adenosine deaminase acting on RNA (ADAR1), a suppressor of double-stranded RNA-triggered innate immune responses.

The Journal Of Biological Chemistry
Samuel, Charles E CE
Publication Date: 2019-02-01

Variant appearance in text: Dicer: E861A
PubMed Link: 30710018
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Balancing Act: MDA5 in Antiviral Immunity and Autoinflammation.

Trends In Microbiology
Dias Junior, Antonio Gregorio AG; Sampaio, Natalia G NG; Rehwinkel, Jan J
Publication Date: 2019-01

Variant appearance in text: Dicer: E861A
PubMed Link: 30201512
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Rewriting the transcriptome: adenosine-to-inosine RNA editing by ADARs.

Genome Biology
Walkley, Carl R CR; Li, Jin Billy JB
Publication Date: 2017-10-30

Variant appearance in text: Dicer: E861A
PubMed Link: 29084589
Variant Present in the following documents:
  • 13059_2017_Article_1347.pdf
View BVdb publication page



An RNA editing/dsRNA binding-independent gene regulatory mechanism of ADARs and its clinical implication in cancer.

Nucleic Acids Research
Qi, Lihua L; Song, Yangyang Y; Chan, Tim Hon Man THM; Yang, Henry H; Lin, Chi Ho CH; Tay, Daryl Jin Tai DJT; Hong, HuiQi H; Tang, Sze Jing SJ; Tan, Kar Tong KT; Huang, Xi Xiao XX; Lin, Jaymie Siqi JS; Ng, Vanessa Hui En VHE; Maury, Julien Jean Pierre JJP; Tenen, Daniel G DG; Chen, Leilei L
Publication Date: 2017-10-13

Variant appearance in text: Dicer: E861A
PubMed Link: 28985428
Variant Present in the following documents:
  • Main text
View BVdb publication page



Protein recoding by ADAR1-mediated RNA editing is not essential for normal development and homeostasis.

Genome Biology
Heraud-Farlow, Jacki E JE; Chalk, Alistair M AM; Linder, Sandra E SE; Li, Qin Q; Taylor, Scott S; White, Joshua M JM; Pang, Lokman L; Liddicoat, Brian J BJ; Gupte, Ankita A; Li, Jin Billy JB; Walkley, Carl R CR
Publication Date: 2017-09-05

Variant appearance in text: Dicer: E861A
PubMed Link: 28874170
Variant Present in the following documents:
  • 13059_2017_Article_1301.pdf
View BVdb publication page



ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay.

Nature Structural & Molecular Biology
Sakurai, Masayuki M; Shiromoto, Yusuke Y; Ota, Hiromitsu H; Song, Chunzi C; Kossenkov, Andrew V AV; Wickramasinghe, Jayamanna J; Showe, Louise C LC; Skordalakes, Emmanuel E; Tang, Hsin-Yao HY; Speicher, David W DW; Nishikura, Kazuko K
Publication Date: 2017-06

Variant appearance in text: Dicer: E861A
PubMed Link: 28436945
Variant Present in the following documents:
  • Main text
View BVdb publication page



ADAR1 is vital for B cell lineage development in the mouse bone marrow.

Oncotarget
Marcu-Malina, Victoria V; Goldberg, Sanja S; Vax, Einav E; Amariglio, Ninette N; Goldstein, Itamar I; Rechavi, Gideon G
Publication Date: 2016-08-23

Variant appearance in text: Dicer: E861A
PubMed Link: 27494846
Variant Present in the following documents:
  • oncotarget-07-54370.pdf
View BVdb publication page



Reprogramming, Circular Reasoning and Self versus Non-self: One-Stop Shopping with RNA Editing.

Frontiers In Genetics
Savva, Yiannis A YA; Rezaei, Ali A; St Laurent, Georges G; Reenan, Robert A RA
Publication Date: 2016

Variant appearance in text: Dicer: E861A
PubMed Link: 27458478
Variant Present in the following documents:
  • Main text
  • fgene-07-00100.pdf
View BVdb publication page



Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis.

Experimental Hematology
Liddicoat, Brian J BJ; Hartner, Jochen C JC; Piskol, Robert R; Ramaswami, Gokul G; Chalk, Alistair M AM; Kingsley, Paul D PD; Sankaran, Vijay G VG; Wall, Meaghan M; Purton, Louise E LE; Seeburg, Peter H PH; Palis, James J; Orkin, Stuart H SH; Lu, Jun J; Li, Jin Billy JB; Walkley, Carl R CR
Publication Date: 2016-10

Variant appearance in text: Dicer: E861A
PubMed Link: 27373493
Variant Present in the following documents:
  • Main text
View BVdb publication page