Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors.
Cell Reports
Vigilante, Alessandra A; Laddach, Anna A; Moens, Nathalie N; Meleckyte, Ruta R; Leha, Andreas A; Ghahramani, Arsham A; Culley, Oliver J OJ; Kathuria, Annie A; Hurling, Chloe C; Vickers, Alice A; Wiseman, Erika E; Tewary, Mukul M; Zandstra, Peter W PW; , ; Durbin, Richard R; Fraternali, Franca F; Stegle, Oliver O; Birney, Ewan E; Luscombe, Nicholas M NM; Danovi, Davide D; Watt, Fiona M FM
Exemestane potency is unchanged by common nonsynonymous polymorphisms in CYP19A1: results of a novel anti-aromatase activity assay examining exemestane and its derivatives.
Pharmacology Research & Perspectives
Peterson, Amity A; Xia, Zuping Z; Chen, Gang G; Lazarus, Philip P
The New Immortalized Uroepithelial Cell Line HBLAK Contains Defined Genetic Aberrations Typical of Early Stage Urothelial Tumors.
Bladder Cancer (Amsterdam, Netherlands)
Hoffmann, Michèle J MJ; Koutsogiannouli, Evangelia E; Skowron, Margaretha A MA; Pinkerneil, Maria M; Niegisch, Günter G; Brandt, Artur A; Stepanow, Stefanie S; Rieder, Harald H; Schulz, Wolfgang A WA
Publication Date: 2016-10-27
Variant appearance in text: CYP19A1: T201M; rs28757184
Generation of a High Number of Healthy Erythroid Cells from Gene-Edited Pyruvate Kinase Deficiency Patient-Specific Induced Pluripotent Stem Cells.
Stem Cell Reports
Garate, Zita Z; Quintana-Bustamante, Oscar O; Crane, Ana M AM; Olivier, Emmanuel E; Poirot, Laurent L; Galetto, Roman R; Kosinski, Penelope P; Hill, Collin C; Kung, Charles C; Agirre, Xabi X; Orman, Israel I; Cerrato, Laura L; Alberquilla, Omaira O; Rodriguez-Fornes, Fatima F; Fusaki, Noemi N; Garcia-Sanchez, Felix F; Maia, Tabita M TM; Ribeiro, Maria L ML; Sevilla, Julian J; Prosper, Felipe F; Jin, Shengfang S; Mountford, Joanne J; Guenechea, Guillermo G; Gouble, Agnes A; Bueren, Juan A JA; Davis, Brian R BR; Segovia, Jose C JC
Publication Date: 2015-12-08
Variant appearance in text: CYP19A1: T201M; rs28757184
Whole-genome sequencing of the world's oldest people.
Plos One
Gierman, Hinco J HJ; Fortney, Kristen K; Roach, Jared C JC; Coles, Natalie S NS; Li, Hong H; Glusman, Gustavo G; Markov, Glenn J GJ; Smith, Justin D JD; Hood, Leroy L; Coles, L Stephen LS; Kim, Stuart K SK
Publication Date: 2014
Variant appearance in text: CYP19A1: T201M; rs28757184
NCI-60 whole exome sequencing and pharmacological CellMiner analyses.
Plos One
Reinhold, William C WC; Varma, Sudhir S; Sousa, Fabricio F; Sunshine, Margot M; Abaan, Ogan D OD; Davis, Sean R SR; Reinhold, Spencer W SW; Kohn, Kurt W KW; Morris, Joel J; Meltzer, Paul S PS; Doroshow, James H JH; Pommier, Yves Y
Publication Date: 2014
Variant appearance in text: CYP19A1: T201M; rs28757184
Impact of aromatase genetic variation on hormone levels and global outcome after severe TBI.
Journal Of Neurotrauma
Garringer, Julie A JA; Niyonkuru, Christian C; McCullough, Emily H EH; Loucks, Tammy T; Dixon, C Edward CE; Conley, Yvette P YP; Berga, Sarah S; Wagner, Amy K AK
Publication Date: 2013-08-15
Variant appearance in text: aromatase: Thr201Met; rs28757184
A non-synonymous coding change in the CYP19A1 gene Arg264Cys (rs700519) does not affect circulating estradiol, bone structure or fracture.
Bmc Medical Genetics
Wang, Jenny Z JZ; Deogan, Mandeep S MS; Lewis, Joshua R JR; Chew, Shelby S; Mullin, Ben H BH; McNab, Tegan J TJ; Wilson, Scott G SG; Ingley, Evan E; Prince, Richard L RL
CYP19A1 genetic variation in relation to prostate cancer risk and circulating sex hormone concentrations in men from the Breast and Prostate Cancer Cohort Consortium.
Cancer Epidemiology, Biomarkers & Prevention : A Publication Of The American Association For Cancer Research, Cosponsored By The American Society Of Preventive Oncology
Travis, Ruth C RC; Schumacher, Fredrick F; Hirschhorn, Joel N JN; Kraft, Peter P; Allen, Naomi E NE; Albanes, Demetrius D; Berglund, Goran G; Berndt, Sonja I SI; Boeing, Heiner H; Bueno-de-Mesquita, H Bas HB; Calle, Eugenia E EE; Chanock, Stephen S; Dunning, Alison M AM; Hayes, Richard R; Feigelson, Heather Spencer HS; Gaziano, J Michael JM; Giovannucci, Edward E; Haiman, Christopher A CA; Henderson, Brian E BE; Kaaks, Rudolf R; Kolonel, Laurence N LN; Ma, Jing J; Rodriguez, Laudina L; Riboli, Elio E; Stampfer, Meir M; Stram, Daniel O DO; Thun, Michael J MJ; Tjønneland, Anne A; Trichopoulos, Dimitrios D; Vineis, Paolo P; Virtamo, Jarmo J; Le Marchand, Loïc L; Hunter, David J DJ
Publication Date: 2009-10
Variant appearance in text: CYP19A1: Thr201Met; rs28757184
Polymorphisms in estrogen biosynthesis and metabolism-related genes, ionizing radiation exposure, and risk of breast cancer among US radiologic technologists.
Breast Cancer Research And Treatment
Sigurdson, Alice J AJ; Bhatti, Parveen P; Chang, Shih-Chen SC; Rajaraman, Preetha P; Doody, Michele M MM; Bowen, Laura L; Simon, Steven L SL; Weinstock, Robert M RM; Linet, Martha S MS; Rosenstein, Marvin M; Stovall, Marilyn M; Alexander, Bruce H BH; Preston, Dale L DL; Struewing, Jeffery P JP
Publication Date: 2009-11
Variant appearance in text: CYP19A1: T201M; rs28757184
A comprehensive examination of CYP19 variation and risk of breast cancer using two haplotype-tagging approaches.
Breast Cancer Research And Treatment
Olson, Janet E JE; Ingle, James N JN; Ma, Cynthia X CX; Pelleymounter, Linda L LL; Schaid, Daniel J DJ; Pankratz, V Shane VS; Vierkant, Robert A RA; Fredericksen, Zachary S ZS; Wu, Yanhong Y; Couch, Fergus J FJ; Vachon, Celine M CM; Sellers, Thomas A TA; Weinshilboum, Richard M RM