Variant ID: 15-58724524-A-G

NM_000236.2(LIPC):c.88+205A>G

This variant was identified in 14 publications




Publications:


Genetically Mediated Lipid Metabolism and Risk of Insulin Resistance: Insights from Mendelian Randomization Studies.

Journal Of Lipid And Atherosclerosis
SY Bu
Publication Date: 2019-09

Variant appearance in text: rs6494005
PubMed Link: 32821703
Variant Present in the following documents:
  • Main text
View BVdb publication page



A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context.

Nature Communications
A Gallois, J Mefford, A Ko, A Vaysse, H Julienne, M Ala-Korpela, M Laakso, N Zaitlen, P Pajukanta, H Aschard
Publication Date: 2019-10-21

Variant appearance in text: rs6494005
PubMed Link: 31636271
Variant Present in the following documents:
  • 41467_2019_12703_MOESM3_ESM.xlsx
View BVdb publication page



Genetic architecture of human plasma lipidome and its link to cardiovascular disease.

Nature Communications
R Tabassum, JT Rämö, P Ripatti, JT Koskela, M Kurki, J Karjalainen, P Palta, S Hassan, J Nunez-Fontarnau, TTJ Kiiskinen, S Söderlund, N Matikainen, MJ Gerl, MA Surma, C Klose, NO Stitziel, H Laivuori, AS Havulinna, SK Service, V Salomaa, M Pirinen, , M Jauhiainen, MJ Daly, NB Freimer, A Palotie, MR Taskinen, K Simons, S Ripatti
Publication Date: 2019-09-24

Variant appearance in text: rs6494005
PubMed Link: 31551469
Variant Present in the following documents:
  • 41467_2019_11954_MOESM6_ESM.xlsx
View BVdb publication page



Multiple genotype-phenotype association study reveals intronic variant pair on SIDT2 associated with metabolic syndrome in a Korean population.

Human Genomics
S Moon, Y Lee, S Won, J Lee
Publication Date: 2018-11-01

Variant appearance in text: rs6494005
PubMed Link: 30382898
Variant Present in the following documents:
  • 40246_2018_180_MOESM1_ESM.pdf
  • aaaaaMain text
View BVdb publication page



New Common and Rare Variants Influencing Metabolic Syndrome and Its Individual Components in a Korean Population.

Scientific Reports
HS Lee, Y Kim, T Park
Publication Date: 2018-04-09

Variant appearance in text: rs6494005
PubMed Link: 29632305
Variant Present in the following documents:
  • 41598_2018_23074_MOESM1_ESM.docx
  • aaaaaMain text
View BVdb publication page



Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study.

Plos Genetics
JP Davis, JR Huyghe, AE Locke, AU Jackson, X Sim, HM Stringham, TM Teslovich, RP Welch, C Fuchsberger, N Narisu, PS Chines, AJ Kangas, P Soininen, M Ala-Korpela, J Kuusisto, FS Collins, M Laakso, M Boehnke, KL Mohlke
Publication Date: 2017-10

Variant appearance in text: rs6494005
PubMed Link: 29084231
Variant Present in the following documents:
  • pgen.1007079.s010.xlsx
View BVdb publication page



On the analysis of a repeated measure design in genome-wide association analysis.

International Journal Of Environmental Research And Public Health
Y Lee, S Park, S Moon, J Lee, RC Elston, W Lee, S Won
Publication Date: 2014-11-28

Variant appearance in text: rs6494005
PubMed Link: 25464127
Variant Present in the following documents:
  • Main text
View BVdb publication page



Diplotyper: diplotype-based association analysis.

Bmc Medical Genomics
S Kim, K Park, C Shin, NH Cho, JJ Ko, I Koh, K Kwack
Publication Date: 2013

Variant appearance in text: rs6494005
PubMed Link: 23819435
Variant Present in the following documents:
  • Main text
View BVdb publication page



Genetic variants from lipid-related pathways and risk for incident myocardial infarction.

Plos One
C Song, NL Pedersen, CA Reynolds, M Sabater-Lleal, S Kanoni, C Willenborg, , AC Syvänen, H Watkins, A Hamsten, JA Prince, E Ingelsson
Publication Date: 2013

Variant appearance in text: rs6494005
PubMed Link: 23555974
Variant Present in the following documents:
  • pone.0060454.s001.pdf
View BVdb publication page



Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors.

American Journal Of Human Genetics
OA Andreassen, S Djurovic, WK Thompson, AJ Schork, KS Kendler, MC O'Donovan, D Rujescu, T Werge, M van de Bunt, AP Morris, MI McCarthy, , , , JC Roddey, LK McEvoy, RS Desikan, AM Dale
Publication Date: 2013-02-07

Variant appearance in text: rs6494005
PubMed Link: 23375658
Variant Present in the following documents:
  • mmc1.pdf
View BVdb publication page



Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

American Journal Of Human Genetics
FW Asselbergs, Y Guo, EP van Iperen, S Sivapalaratnam, V Tragante, MB Lanktree, LA Lange, B Almoguera, YE Appelman, J Barnard, J Baumert, AL Beitelshees, TR Bhangale, YD Chen, TR Gaunt, Y Gong, JC Hopewell, T Johnson, ME Kleber, TY Langaee, M Li, YR Li, K Liu, CW McDonough, MF Meijs, RP Middelberg, K Musunuru, CP Nelson, JR O'Connell, S Padmanabhan, JS Pankow, N Pankratz, S Rafelt, R Rajagopalan, SP Romaine, NJ Schork, J Shaffer, H Shen, EN Smith, SE Tischfield, PJ van der Most, JV van Vliet-Ostaptchouk, N Verweij, KA Volcik, L Zhang, KR Bailey, KM Bailey, F Bauer, JM Boer, PS Braund, A Burt, PR Burton, SG Buxbaum, W Chen, RM Cooper-Dehoff, LA Cupples, JS deJong, C Delles, D Duggan, M Fornage, CE Furlong, N Glazer, JG Gums, C Hastie, MV Holmes, T Illig, SA Kirkland, M Kivimaki, R Klein, BE Klein, C Kooperberg, K Kottke-Marchant, M Kumari, AZ LaCroix, L Mallela, G Murugesan, J Ordovas, WH Ouwehand, WS Post, R Saxena, H Scharnagl, PJ Schreiner, T Shah, DC Shields, D Shimbo, SR Srinivasan, RP Stolk, DI Swerdlow, HA Taylor, EJ Topol, E Toskala, JL van Pelt, J van Setten, S Yusuf, JC Whittaker, AH Zwinderman, , SS Anand, AJ Balmforth, GS Berenson, CR Bezzina, BO Boehm, E Boerwinkle, JP Casas, MJ Caulfield, R Clarke, JM Connell, KJ Cruickshanks, KW Davidson, IN Day, PI de Bakker, PA Doevendans, AF Dominiczak, AS Hall, CA Hartman, C Hengstenberg, HL Hillege, MH Hofker, SE Humphries, GP Jarvik, JA Johnson, BM Kaess, S Kathiresan, W Koenig, DA Lawlor, W März, O Melander, BD Mitchell, GW Montgomery, PB Munroe, SS Murray, SJ Newhouse, NC Onland-Moret, N Poulter, B Psaty, S Redline, SS Rich, JI Rotter, H Schunkert, P Sever, AR Shuldiner, RL Silverstein, A Stanton, B Thorand, MD Trip, MY Tsai, P van der Harst, E van der Schoot, YT van der Schouw, WM Verschuren, H Watkins, AA Wilde, BH Wolffenbuttel, JB Whitfield, GK Hovingh, CM Ballantyne, C Wijmenga, MP Reilly, NG Martin, JG Wilson, DJ Rader, NJ Samani, AP Reiner, RA Hegele, JJ Kastelein, AD Hingorani, PJ Talmud, H Hakonarson, CC Elbers, BJ Keating, F Drenos
Publication Date: 2012-11-02

Variant appearance in text: rs6494005
PubMed Link: 23063622
Variant Present in the following documents:
  • mmc4.xls
View BVdb publication page



Dense genotyping of candidate gene loci identifies variants associated with high-density lipoprotein cholesterol.

Circulation. Cardiovascular Genetics
AC Edmondson, PS Braund, IM Stylianou, AV Khera, CP Nelson, ML Wolfe, SL Derohannessian, BJ Keating, L Qu, J He, MD Tobin, M Tomaszewski, J Baumert, N Klopp, A Döring, B Thorand, M Li, MP Reilly, W Koenig, NJ Samani, DJ Rader
Publication Date: 2011-04

Variant appearance in text: rs6494005
PubMed Link: 21303902
Variant Present in the following documents:
  • NIHMS280051-supplement-1.pdf
View BVdb publication page



Genome-wide association of lipid-lowering response to statins in combined study populations.

Plos One
MJ Barber, LM Mangravite, CL Hyde, DI Chasman, JD Smith, CA McCarty, X Li, RA Wilke, MJ Rieder, PT Williams, PM Ridker, A Chatterjee, JI Rotter, DA Nickerson, M Stephens, RM Krauss
Publication Date: 2010-03-22

Variant appearance in text: rs6494005
PubMed Link: 20339536
Variant Present in the following documents:
  • pone.0009763.s007.xls
View BVdb publication page



Genomewide association analysis of coronary artery disease.

The New England Journal Of Medicine
NJ Samani, J Erdmann, AS Hall, C Hengstenberg, M Mangino, B Mayer, RJ Dixon, T Meitinger, P Braund, HE Wichmann, JH Barrett, IR König, SE Stevens, S Szymczak, DA Tregouet, MM Iles, F Pahlke, H Pollard, W Lieb, F Cambien, M Fischer, W Ouwehand, S Blankenberg, AJ Balmforth, A Baessler, SG Ball, TM Strom, I Braenne, C Gieger, P Deloukas, MD Tobin, A Ziegler, JR Thompson, H Schunkert,
Publication Date: 2007-08-02

Variant appearance in text: rs6494005
PubMed Link: 17634449
Variant Present in the following documents:
  • NIHMS4594-supplement-S1.pdf
View BVdb publication page



Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000299022.5 c.88+205A>G - intron_variant - 1/8
ENST00000356113.6 c.88+205A>G - intron_variant - 3/10
ENST00000414170.3 c.88+205A>G - intron_variant - 2/9
ENST00000433326.2 c.88+205A>G - intron_variant - 1/7
ENST00000558239.1 c.-306-12220T>C - intron_variant - 1/3
ENST00000559845.1 n.130+205A>G - intron_variant,non_coding_transcript_variant - 1/6
ENST00000560257.1 n.896A>G - non_coding_transcript_exon_variant 3/3 -
ENST00000560863.1 n.281-12220T>C - intron_variant,non_coding_transcript_variant - 2/4
NM_000236.3 c.88+205A>G - intron_variant - 1/8