Publications:

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Tracking and blocking interdependencies of cellular BRAF-MEK oncokinase activities.

Pnas Nexus

Fleischmann, Jakob J; Schwaighofer, Selina S; De Falco, Louis L; Enzler, Florian F; Feichtner, Andreas A; Kugler, Valentina V; Tschaikner, Philipp P; Huber, Roland G RG; Stefan, Eduard E

Publication Date: 2023-06

Variant appearance in text: MEK1: K57N

PubMed Link: 37325027

Variant Present in the following documents:

• Main text
• pgad185.pdf

View BVdb publication page

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Dynamic ctDNA Mutational Complexity in Patients with Melanoma Receiving Immunotherapy.

Molecular Diagnosis & Therapy

Fitzgerald, Sandra S; Blenkiron, Cherie C; Stephens, Rosalie R; Mathy, Jon A JA; Somers-Edgar, Tiffany T; Rolfe, Gill G; Martin, Richard R; Jackson, Christopher C; Eccles, Michael M; Robb, Tamsin T; Rodger, Euan E; Lawrence, Ben B; Guilford, Parry P; Lasham, Annette A; Print, Cristin G CG

Publication Date: 2023-04-26

Variant appearance in text: MAP2K1: 171G>T; K57N

PubMed Link: 37099071

Variant Present in the following documents:

• 40291_2023_651_MOESM1_ESM.xlsx, sheet 2

View BVdb publication page

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Corrigendum: Case report: MAP2K1 K57N mutation is associated with primary resistance to anti-EGFR monoclonal antibodies in metastatic colorectal cancer.

Frontiers In Oncology

Mauri, Gianluca G; Patelli, Giorgio G; Gori, Viviana V; Lauricella, Calogero C; Mussolin, Benedetta B; Amatu, Alessio A; Bencardino, Katia K; Tosi, Federica F; Bonazzina, Erica E; Bonoldi, Emanuela E; Bardelli, Alberto A; Siena, Salvatore S; Sartore-Bianchi, Andrea A

Publication Date: 2023

Variant appearance in text: MAP2K1: K57N

PubMed Link: 37056342

Variant Present in the following documents:

• fonc-13-1147497.pdf

View BVdb publication page

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Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA.

Nature

Abbosh, Christopher C; Frankell, Alexander M AM; Harrison, Thomas T; Kisistok, Judit J; Garnett, Aaron A; Johnson, Laura L; Veeriah, Selvaraju S; Moreau, Mike M; Chesh, Adrian A; Chaunzwa, Tafadzwa L TL; Weiss, Jakob J; Schroeder, Morgan R MR; Ward, Sophia S; Grigoriadis, Kristiana K; Shahpurwalla, Aamir A; Litchfield, Kevin K; Puttick, Clare C; Biswas, Dhruva D; Karasaki, Takahiro T; Black, James R M JRM; Martínez-Ruiz, Carlos C; Bakir, Maise Al MA; Pich, Oriol O; Watkins, Thomas B K TBK; Lim, Emilia L EL; Huebner, Ariana A; Moore, David A DA; Godin-Heymann, Nadia N; L'Hernault, Anne A; Bye, Hannah H; Odell, Aaron A; Roberts, Paula P; Gomes, Fabio F; Patel, Akshay J AJ; Manzano, Elizabeth E; Hiley, Crispin T CT; Carey, Nicolas N; Riley, Joan J; Cook, Daniel E DE; Hodgson, Darren D; Stetson, Daniel D; Barrett, J Carl JC; Kortlever, Roderik M RM; Evan, Gerard I GI; Hackshaw, Allan A; Daber, Robert D RD; Shaw, Jacqui A JA; Aerts, Hugo J W L HJWL; Licon, Abel A; Stahl, Josh J; Jamal-Hanjani, Mariam M; , ; Birkbak, Nicolai J NJ; McGranahan, Nicholas N; Swanton, Charles C

Publication Date: 2023-04-13

Variant appearance in text: MAP2K1: K57N

PubMed Link: 37055640

Variant Present in the following documents:

• EMS176197-supplement-Supplementary_Table_1.xlsx, sheet 18

View BVdb publication page

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: MAP2K1: K57N

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
• 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3
• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 3

View BVdb publication page

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Direct GDP-KRASG12C inhibitors and mechanisms of resistance: the tip of the iceberg.

Therapeutic Advances In Medical Oncology

Rosen, Joshua C JC; Sacher, Adrian A; Tsao, Ming-Sound MS

Publication Date: 2023

Variant appearance in text: MEK1: K57N

PubMed Link: 36950276

Variant Present in the following documents:

• Main text
• 10.1177_17588359231160141.pdf

View BVdb publication page

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Development and validation of a mutation-based model to predict immunotherapeutic efficacy in NSCLC.

Frontiers In Oncology

He, Ping P; Liu, Jie J; Xu, Qingyuan Q; Ma, Huaijun H; Niu, Beifang B; Huang, Gang G; Wu, Wei W

Publication Date: 2023

Variant appearance in text: MAP2K1: 171G>T; K57N; rs869025608

PubMed Link: 36910641

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 8

View BVdb publication page

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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery

Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI

Publication Date: 2023-03-02

Variant appearance in text: MAP2K1: 171G>T; K57N; rs869025608

PubMed Link: 36862804

Variant Present in the following documents:

• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 10
• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 6

View BVdb publication page

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Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: MAP2K1: 171G>T; Lys57Asn

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Caspase 3-specific cleavage of MEK1 suppresses ERK signaling and sensitizes cells to stress-induced apoptosis.

Febs Open Bio

Moriizumi, Hisashi H; Kubota, Yuji Y; Tsuchiya, Tomoyuki T; Naka, Ryosuke R; Takekawa, Mutsuhiro M

Publication Date: 2023-02-13

Variant appearance in text: MEK1: K57N

PubMed Link: 36776127

Variant Present in the following documents:

• Main text
• FEB4-13-684.pdf

View BVdb publication page

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Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications

Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI

Publication Date: 2023-02-08

Variant appearance in text: MAP2K1: 171G>T; K57N

PubMed Link: 36755027

Variant Present in the following documents:

• 41467_2023_36328_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Combined KRAS G12C and SOS1 inhibition enhances and extends the anti-tumor response in KRAS G12C -driven cancers by addressing intrinsic and acquired resistance.

Biorxiv : The Preprint Server For Biology

Thatikonda, Venu V; Lu, Hengyu H; Jurado, Sabine S; Kostyrko, Kaja K; Bristow, Christopher A CA; Bosch, Karin K; Feng, Ningping N; Gao, Sisi S; Gerlach, Daniel D; Gmachl, Michael M; Lieb, Simone S; Jeschko, Astrid A; Machado, Annette A AA; Marszalek, Ethan D ED; Mahendra, Mikhila M; Jaeger, Philipp A PA; Sorokin, Alexey A; Strauss, Sandra S; Trapani, Francesca F; Kopetz, Scott S; Vellano, Christopher P CP; Petronczki, Mark M; Kraut, Norbert N; Heffernan, Timothy P TP; Marszalek, Joseph R JR; Pearson, Mark M; Waizenegger, Irene I; Hofmann, Marco H MH

Publication Date: 2023-01-23

Variant appearance in text: MAP2K1: K57N

PubMed Link: 36747713

Variant Present in the following documents:

• media-1.xlsx, sheet 4

View BVdb publication page

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Characterization of driver mutations in Chinese non-small cell lung cancer patients using a novel targeted sequencing panel.

Journal Of Thoracic Disease

Zhao, Jing J; Wu, Yang Y; Chen, Min-Jiang MJ; Xu, Yan Y; Zhong, Wei W; Wang, Meng-Zhao MZ

Publication Date: 2022-12

Variant appearance in text: MAP2K1: K57N

PubMed Link: 36647494

Variant Present in the following documents:

• Main text
• jtd-14-12-4669.pdf

View BVdb publication page

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Clinical utility of liquid biopsy and integrative genomic profiling in early-stage and oligometastatic cancer patients treated with radiotherapy.

British Journal Of Cancer

Cifuentes, Guadalupe A GA; Santiago, Adrián A; Méndez Blanco, Lucía L; Fueyo, María M; López Martínez, Esther E; Soria, Raquel R; Martín López, Irene I; Cucarella Beltrán, Pepa P; Pardo-Coto, Pablo P; Rodriguez-Rubi, David D; Urquilla, Karla K; Durán, Noelia S NS; Álvarez, Rebeca R; Lago, Claudia G CG; Otero, Andrea A; Diñeiro, Marta M; Capín, Raquel R; Cadiñanos, Juan J; Cabanillas, Rubén R

Publication Date: 2022-12-22

Variant appearance in text: MAP2K1: 171G>T; Lys57Asn

PubMed Link: 36550207

Variant Present in the following documents:

• Main text
• 41416_2022_Article_2102.pdf
• 41416_2022_2102_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Molecular pathways, resistance mechanisms and targeted interventions in non-small-cell lung cancer.

Molecular Biomedicine

Wang, Zixi Z; Xing, Yurou Y; Li, Bingjie B; Li, Xiaoyu X; Liu, Bin B; Wang, Yongsheng Y

Publication Date: 2022-12-12

Variant appearance in text: MEK1: K57N

PubMed Link: 36508072

Variant Present in the following documents:

• Main text
• 43556_2022_Article_107.pdf

View BVdb publication page

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High-throughput functional evaluation of MAP2K1 variants in cancer.

Molecular Cancer Therapeutics

Mizuno, Sho S; Ikegami, Masachika M; Koyama, Takafumi T; Sunami, Kuniko K; Ogata, Dai D; Kage, Hidenori H; Yanagaki, Mitsuru M; Ikeuchi, Hiroshi H; Ueno, Toshihide T; Tanikawa, Michihiro M; Oda, Katsutoshi K; Osuga, Yutaka Y; Mano, Hiroyuki H; Kohsaka, Shinji S

Publication Date: 2022-11-28

Variant appearance in text: MAP2K1: K57N

PubMed Link: 36442478

Variant Present in the following documents:

• Main text
• mct-22-0302_supplementary_tables_suppst.xlsx, sheet 3
• mct-22-0302_supplementary_tables_suppst.xlsx, sheet 7
• mct-22-0302_supplementary_tables_suppst.xlsx, sheet 8
• 227.pdf

View BVdb publication page

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Case Report: MAP2K1 K57N mutation is associated with primary resistance to anti-EGFR monoclonal antibodies in metastatic colorectal cancer.

Frontiers In Oncology

Mauri, Gianluca G; Patelli, Giorgio G; Gori, Viviana V; Lauricella, Calogero C; Mussolin, Benedetta B; Amatu, Alessio A; Bencardino, Katia K; Tosi, Federica F; Bonazzina, Erica E; Bonoldi, Emanuela E; Bardelli, Alberto A; Siena, Salvatore S; Sartore-Bianchi, Andrea A

Publication Date: 2022

Variant appearance in text: MAP2K1: K57N

PubMed Link: 36419886

Variant Present in the following documents:

• Main text
• fonc-12-1030232.pdf

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: MAP2K1: K57N

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Clinical characteristics of 10 Chinese patients with melorheostosis and identification of a somatic MAP2K1 variant in one case.

Molecular Genetics & Genomic Medicine

Han, Xiaojun X; Xu, Yang Y; Wei, Zhanying Z; Wang, Chun C; Yue, Hua H; Zhang, Zhenlin Z

Publication Date: 2022-10

Variant appearance in text: MEK1: Lys57Asn

PubMed Link: 36004822

Variant Present in the following documents:

• Main text
• MGG3-10-e2043.pdf

View BVdb publication page

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Genomic Landscape of RTK/RAS Pathway and Tumor Immune Infiltration as Prognostic Indicator of Lung Adenocarcinoma.

Frontiers In Oncology

Yin, Xiang-Qian XQ; Yin, Xue-Hui XH; Yu, Ya-Qin YQ; Xu, Lang L; Zhang, Mao M

Publication Date: 2022

Variant appearance in text: MAP2K1: 171G>T; K57N

PubMed Link: 35936718

Variant Present in the following documents:

• Table_4.xlsx, sheet 2

View BVdb publication page

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Pediatric-Type Indolent B-Cell Lymphomas With Overlapping Clinical, Pathologic, and Genetic Features.

The American Journal Of Surgical Pathology

Lim, Sojung S; Lim, Ka Young KY; Koh, Jiwon J; Bae, Jeong Mo JM; Yun, Hongseok H; Lee, Cheol C; Kim, Young A YA; Paik, Jin Ho JH; Jeon, Yoon Kyung YK

Publication Date: 2022-10-01

Variant appearance in text: MAP2K1: K57N

PubMed Link: 35834399

Variant Present in the following documents:

• pas-46-1397-s003.xlsx, sheet 1

View BVdb publication page

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Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.

Nature Communications

Kubota, Yuji Y; Fujioka, Yuko Y; Patil, Ashwini A; Takagi, Yusuke Y; Matsubara, Daisuke D; Iijima, Masatomi M; Momose, Isao I; Naka, Ryosuke R; Nakai, Kenta K; Noda, Nobuo N NN; Takekawa, Mutsuhiro M

Publication Date: 2022-07-13

Variant appearance in text: MEK1: K57N

PubMed Link: 35831322

Variant Present in the following documents:

• Main text
• 41467_2022_31690_MOESM7_ESM.xlsx, sheet 50
• 41467_2022_31690_MOESM7_ESM.xlsx, sheet 22
• 41467_2022_31690_MOESM7_ESM.xlsx, sheet 4
• 41467_2022_31690_MOESM7_ESM.xlsx, sheet 14
• 41467_2022_31690_MOESM7_ESM.xlsx, sheet 21
• 41467_2022_31690_MOESM7_ESM.xlsx, sheet 17
• 41467_2022_31690_MOESM7_ESM.xlsx, sheet 52
• 41467_2022_31690_MOESM7_ESM.xlsx, sheet 92
• 41467_2022_31690_MOESM1_ESM.pdf
• 41467_2022_31690_MOESM7_ESM.xlsx, sheet 16
• 41467_2022_31690_MOESM7_ESM.xlsx, sheet 19
• 41467_2022_Article_31690.pdf
• 41467_2022_31690_MOESM7_ESM.xlsx, sheet 15
• 41467_2022_31690_MOESM7_ESM.xlsx, sheet 78
• 41467_2022_31690_MOESM7_ESM.xlsx, sheet 20

View BVdb publication page

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Nosological and Theranostic Approach to Vascular Malformation through cfDNA NGS Liquid Biopsy.

Journal Of Clinical Medicine

Serio, Viola Bianca VB; Palmieri, Maria M; Loberti, Lorenzo L; Granata, Stefania S; Fallerini, Chiara C; Vaghi, Massimo M; Renieri, Alessandra A; Pinto, Anna Maria AM

Publication Date: 2022-06-28

Variant appearance in text: MAP2K1: 171G>T; Lys57Asn

PubMed Link: 35807022

Variant Present in the following documents:

• Main text
• jcm-11-03740.pdf

View BVdb publication page

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Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells.

Nature Communications

Robinson, Philip S PS; Thomas, Laura E LE; Abascal, Federico F; Jung, Hyunchul H; Harvey, Luke M R LMR; West, Hannah D HD; Olafsson, Sigurgeir S; Lee, Bernard C H BCH; Coorens, Tim H H THH; Lee-Six, Henry H; Butlin, Laura L; Lander, Nicola N; Truscott, Rebekah R; Sanders, Mathijs A MA; Lensing, Stefanie V SV; Buczacki, Simon J A SJA; Ten Hoopen, Rogier R; Coleman, Nicholas N; Brunton-Sim, Roxanne R; Rushbrook, Simon S; Saeb-Parsy, Kourosh K; Lalloo, Fiona F; Campbell, Peter J PJ; Martincorena, Iñigo I; Sampson, Julian R JR; Stratton, Michael R MR

Publication Date: 2022-07-08

Variant appearance in text: MAP2K1: K57N

PubMed Link: 35803914

Variant Present in the following documents:

• 41467_2022_31341_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: MAP2K1: 171G>T; K57N

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

View BVdb publication page

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A unifying hypothesis for PNMZL and PTFL: morphological variants with a common molecular profile.

Blood Advances

Salmeron-Villalobos, Julia J; Egan, Caoimhe C; Borgmann, Vanessa V; Müller, Inga I; Gonzalez-Farre, Blanca B; Ramis-Zaldivar, Joan Enric JE; Nann, Dominik D; Balagué, Olga O; López-Guerra, Mónica M; Colomer, Dolors D; Oschlies, Ilske I; Klapper, Wolfram W; Glaser, Selina S; Ko, Young Hyeh YH; Bonzheim, Irina I; Siebert, Reiner R; Fend, Falko F; Pittaluga, Stefania S; Campo, Elias E; Salaverria, Itziar I; Jaffe, Elaine S ES; Quintanilla-Martinez, Leticia L

Publication Date: 2022-08-23

Variant appearance in text: MAP2K1: 171G>T; K57N

PubMed Link: 35609565

Variant Present in the following documents:

• advancesADV2022007322-suppl1.pdf

View BVdb publication page

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Feasibility and clinical utility of comprehensive genomic profiling of hematological malignancies.

Cancer Science

Fukuhara, Suguru S; Oshikawa-Kumade, Yuji Y; Kogure, Yasunori Y; Shingaki, Sumito S; Kariyazono, Hirokazu H; Kikukawa, Yoshiya Y; Koya, Junji J; Saito, Yuki Y; Tabata, Mariko M; Yoshifuji, Kota K; Mizuno, Kota K; Miyagi-Maeshima, Akiko A; Matsushita, Hiromichi H; Sugiyama, Masanaka M; Ogawa, Chitose C; Inamoto, Yoshihiro Y; Fukuda, Takahiro T; Sugano, Masato M; Yamauchi, Nobuhiko N; Minami, Yosuke Y; Hirata, Makoto M; Yoshida, Teruhiko T; Kohno, Takashi T; Kohsaka, Shinji S; Mano, Hiroyuki H; Shiraishi, Yuichi Y; Ogawa, Seishi S; Izutsu, Koji K; Kataoka, Keisuke K

Publication Date: 2022-08

Variant appearance in text: MEK1: K57N

PubMed Link: 35579198

Variant Present in the following documents:

• CAS-113-2763-s003.xlsx, sheet 6

View BVdb publication page

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Author Correction: Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11.21 to metastasis.

Nature Communications

Farshidfar, Farshad F; Rhrissorrakrai, Kahn K; Levovitz, Chaya C; Peng, Cong C; Knight, James J; Bacchiocchi, Antonella A; Su, Juan J; Yin, Mingzhu M; Sznol, Mario M; Ariyan, Stephan S; Clune, James J; Olino, Kelly K; Parida, Laxmi L; Nikolaus, Joerg J; Zhang, Meiling M; Zhao, Shuang S; Wang, Yan Y; Huang, Gang G; Wan, Miaojian M; Li, Xianan X; Cao, Jian J; Yan, Qin Q; Chen, Xiang X; Newman, Aaron M AM; Halaban, Ruth R

Publication Date: 2022-05-10

Variant appearance in text: MAP2K1: K57N

PubMed Link: 35538087

Variant Present in the following documents:

• 41467_2022_30446_MOESM1_ESM.xlsx, sheet 2

View BVdb publication page

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Deciphering Genetic Alterations of Hairy Cell Leukemia and Hairy Cell Leukemia-like Disorders in 98 Patients.

Cancers

Maitre, Elsa E; Tomowiak, Cécile C; Lebecque, Benjamin B; Bijou, Fontanet F; Benabed, Khaled K; Naguib, Dina D; Kerneves, Pauline P; Cornet, Edouard E; Viailly, Pierre-Julien PJ; Arsham, Jeffrey J; Sola, Brigitte B; Jardin, Fabrice F; Troussard, Xavier X

Publication Date: 2022-04-10

Variant appearance in text: MAP2K1: K57N

PubMed Link: 35454811

Variant Present in the following documents:

• Main text

View BVdb publication page

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Custom multi‑tumor next‑generation sequencing panel for routine molecular diagnosis of solid tumors: Validation and results from three‑year clinical use.

International Journal Of Molecular Medicine

Chevrier, Sandy S; Brasselet, Astrid A; Carnet, Marion M; Chevriaux, Angélique A; Gibeaud, Anne A; Jourdain, Marine M; Mananet, Hugo H; Truntzer, Caroline C; Beltjens, Françoise F; Charon-Barra, Céline C; Arnould, Laurent L; Albuisson, Juliette J; Comte, Anthony A; Derangère, Valentin V; Goussot, Vincent V; Boidot, Romain R

Publication Date: 2022-05

Variant appearance in text: MAP2K1: 171G>T; Lys57Asn

PubMed Link: 35244186

Variant Present in the following documents:

• Supplementary_Data2.xlsx, sheet 1
• Supplementary_Data3.xlsx, sheet 1

View BVdb publication page

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: MAP2K1: Lys57Asn

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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ISSVA Classification of Vascular Anomalies and Molecular Biology.

International Journal Of Molecular Sciences

Kunimoto, Kayo K; Yamamoto, Yuki Y; Jinnin, Masatoshi M

Publication Date: 2022-02-21

Variant appearance in text: MAP2K1: K57N

PubMed Link: 35216474

Variant Present in the following documents:

• Main text
• ijms-23-02358.pdf

View BVdb publication page

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Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11.21 to metastasis.

Nature Communications

Farshidfar, Farshad F; Rhrissorrakrai, Kahn K; Levovitz, Chaya C; Peng, Cong C; Knight, James J; Bacchiocchi, Antonella A; Su, Juan J; Yin, Mingzhu M; Sznol, Mario M; Ariyan, Stephan S; Clune, James J; Olino, Kelly K; Parida, Laxmi L; Nikolaus, Joerg J; Zhang, Meiling M; Zhao, Shuang S; Wang, Yan Y; Huang, Gang G; Wan, Miaojian M; Li, Xianan X; Cao, Jian J; Yan, Qin Q; Chen, Xiang X; Newman, Aaron M AM; Halaban, Ruth R

Publication Date: 2022-02-23

Variant appearance in text: MAP2K1: K57N

PubMed Link: 35197475

Variant Present in the following documents:

• 41467_2022_28566_MOESM5_ESM.xlsx, sheet 2

View BVdb publication page

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RAS Mutation Conversion in Bevacizumab-Treated Metastatic Colorectal Cancer Patients: A Liquid Biopsy Based Study.

Cancers

Nicolazzo, Chiara C; Belardinilli, Francesca F; Vestri, Annarita A; Magri, Valentina V; De Renzi, Gianluigi G; De Meo, Michela M; Caponnetto, Salvatore S; Di Nicolantonio, Federica F; Cortesi, Enrico E; Giannini, Giuseppe G; Gazzaniga, Paola P

Publication Date: 2022-02-04

Variant appearance in text: MAP2K1: 171G>T; K57N

PubMed Link: 35159069

Variant Present in the following documents:

• Main text

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RAS Mutation Conversion in Bevacizumab-Treated Metastatic Colorectal Cancer Patients: A Liquid Biopsy Based Study.

Cancers

Nicolazzo, Chiara C; Belardinilli, Francesca F; Vestri, Annarita A; Magri, Valentina V; De Renzi, Gianluigi G; De Meo, Michela M; Caponnetto, Salvatore S; Di Nicolantonio, Federica F; Cortesi, Enrico E; Giannini, Giuseppe G; Gazzaniga, Paola P

Publication Date: 2022-02-04

Variant appearance in text: MAP2K1: 171G>T; K57N

PubMed Link: 35159069

Variant Present in the following documents:

• Main text

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The Genomics of Hairy Cell Leukaemia and Splenic Diffuse Red Pulp Lymphoma.

Cancers

Oscier, David D; Stamatopoulos, Kostas K; Mirandari, Amatta A; Strefford, Jonathan J

Publication Date: 2022-01-29

Variant appearance in text: MAP2K1: K57N

PubMed Link: 35158965

Variant Present in the following documents:

• Main text

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The Genomics of Hairy Cell Leukaemia and Splenic Diffuse Red Pulp Lymphoma.

Cancers

Oscier, David D; Stamatopoulos, Kostas K; Mirandari, Amatta A; Strefford, Jonathan J

Publication Date: 2022-01-29

Variant appearance in text: MAP2K1: K57N

PubMed Link: 35158965

Variant Present in the following documents:

• Main text

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KRAS and RAS-MAPK Pathway Deregulation in Mature B Cell Lymphoproliferative Disorders.

Cancers

Vendramini, Elena E; Bomben, Riccardo R; Pozzo, Federico F; Bittolo, Tamara T; Tissino, Erika E; Gattei, Valter V; Zucchetto, Antonella A

Publication Date: 2022-01-28

Variant appearance in text: MAP2K1: K57N

PubMed Link: 35158933

Variant Present in the following documents:

• cancers-14-00666.pdf

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KRAS and RAS-MAPK Pathway Deregulation in Mature B Cell Lymphoproliferative Disorders.

Cancers

Vendramini, Elena E; Bomben, Riccardo R; Pozzo, Federico F; Bittolo, Tamara T; Tissino, Erika E; Gattei, Valter V; Zucchetto, Antonella A

Publication Date: 2022-01-28

Variant appearance in text: MAP2K1: K57N

PubMed Link: 35158933

Variant Present in the following documents:

• cancers-14-00666.pdf

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Resistance to KRASG12C Inhibitors in Non-Small Cell Lung Cancer.

Frontiers In Oncology

Blaquier, Juan Bautista JB; Cardona, Andrés Felipe AF; Recondo, Gonzalo G

Publication Date: 2021

Variant appearance in text: MAP2K1: K57N

PubMed Link: 35004309

Variant Present in the following documents:

• Main text

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